Research on the potential benefits of GABA (gamma-aminobutyric acid) in preventing or alleviating Bone pain is limited, and no conclusive evidence has been found to support its effectiveness. GABA is an inhibitory neurotransmitter in the central nervous system, known for its calming effects and its potential role in pain modulation. While GABA receptors are present in bone tissue, the current understanding of GABA's involvement in Bone pain is still in its early stages.
A review of existing studies in 2017 explored the relationship between GABA and bone health, highlighting the need for further investigation. Some preliminary animal and in vitro studies have suggested that GABA and GABAergic compounds might have a potential role in bone remodeling and pain regulation. However, the effects on Bone pain specifically have not been extensively studied in humans, and no clinical trials have yet been conducted to investigate the efficacy of GABA in the prevention or treatment of Bone pain
