NOW Supplements Alpha GPC

Supplement Facts

Serving Size: 2 Veg Capsules

Amount Per Serving

%DV

Alpha GPC (L-alpha-glycerylphosphorylcholine)

600 mg

The product is found useful for the following medical conditions

We investigated the potential benefits of alpha-glyceryl-phosphoryl-choline (α-GPC) in tackling the complex challenges of Alzheimer's disease (AD). Using a triple transgenic mouse model known as 3xTg-AD, mice were treated with α-GPC for eight months starting at four months of age. This approach allowed us to assess its impact on both neuroinflammation and memory over a significant timeframe.

Our findings revealed that chronic treatment with α-GPC led to a notable reduction in amyloid deposits, which are often associated with AD. We observed improvements in the balance of the immune response within the brain, especially among important cells like astrocytes and microglia. These changes reflected not just a decrease in inflammation but also an increase in protective, anti-inflammatory molecules.

Furthermore, the treatment positively influenced synaptic function, crucial for memory and learning. Behaviorally, the α-GPC-treated mice demonstrated enhanced cognitive abilities, as evidenced by longer exploration times of new objects—a key indicator of memory function—compared to their untreated counterparts.

In summary, our research supports α-GPC as a promising candidate for therapeutic intervention in the early stages of Alzheimer's. Its ability to reduce inflammation and support brain health could provide new avenues for aiding memory and cognitive function as we age.

8.8

Enhances memory clarity

Most Useful Review

Alpha GPC greatly enhances my nootropic regimen, particularly in improving short-term memory. I incorporate it with a group of B vitamins, DMAE capsules, and magnesium. Memory issues, even in young individuals, can sometimes stem from forgetfulness due to stress. I encourage anyone facing these challenges, including those concerned about Alzheimer’s, to consider it as it has greatly benefitted me.

Atrial Septal Defect details

Improved communication

Most Useful Review

Perfectly! Whether my child has an atrial septal defect or not, he does not speak well yet. The beloved jar has brought so much joy to our home. At the age of 3, my daughter was silent and frequently had tantrums. The doctor prescribed gliatilin (ALPHA GPC) and Cerebrolysin (injections). Although gliatilin is not convenient to administer, the latter is easy to mix with a drink. After starting the treatment, her understanding improved, tantrums lessened, and her speech and communication began to develop. Kindergarten teachers no longer have complaints!

Autism details

Blessings to those who created this supplement for my daughter with autism! It was recommended to us, and we are witnessing significant changes, despite it being accompanied by other treatments. Thank you, iHerb!

Back Pain details

I initially bought this to assist with my ADHD but was disappointed after using most of the bottle without notable changes, leading me to stop. However, after introducing a B-Complex and vitamin D3, I resumed taking it and noticed a significant improvement. About half an hour after ingestion, my mind feels much clearer and sharper, making it much easier to focus and think. It works for me now, provided I complement it with those vitamins.

Blurred Vision details

Improved vision and mood! I have no idea how this supplement works, but it does! I have been taking it for just two weeks, only one capsule a day instead of the recommended two. My vision has become noticeably clearer. Two weeks ago, I thought the house opposite was far enough away, and people couldn't see what was happening in my apartment. Now, I am not so sure! The clarity of my vision has greatly improved. I am delighted; I have more energy, and my mood has brightened. I feel inspired to create and learn new things, all from just one capsule a day! I do take it alongside cod liver oil and sunflower lecithin as well.

Food Poisoning details

Great product for brain support! The quality is excellent, just like all NOW Foods products! The ingredients are natural, without unnecessary additives, and the alpha-GPC is in a well-absorbed form. The capsules are a convenient size and easy to swallow. The dosage of 300 mg is ideal, especially when taken 1-2 times daily. After just a couple of weeks, I noticed an improvement in my concentration and clarity of thought. An excellent supplement for cognitive support!

Irritable Bowel Syndrome details

Improved bowel function

Most Useful Review

Superb quality product. The ingredients are perfectly selected. There were no allergies or negative reactions. The package size is large, lasting a long time. The capsule size is average, and the taste is neutral. The dietary supplement arrived quickly and undamaged. It contains only useful and natural components, including folic acid. My bowel function and metabolism have improved. I noticed the first results after a week of use, and my nervous system functions better; I’ve become less anxious. I am very pleased, and I have no doubts about the vitamin's effectiveness. Ensure to check the dosage for your age.

Sleep Apnea details

Sleep quality enhancement

Most Useful Review

The quality of my sleep has improved. Initially bought for my child, when I tried it, I noticed an improvement in my own sleep quality. Although it can be tough to consume due to its size and gritty texture, I mix a small amount into yoghurt for my child. I’m hopeful for continued positive effects.

Dizziness details

Alpha GPC from Now is an exceptionally effective brain supplement that saved me from severe dizziness, which doctors could not diagnose. Now, I take GPC, vitamins, bacopa, magnesium, and other supplements to boost brain function. My condition has improved significantly, and after completing the GPC course, I will begin taking GABA. The capsules are of medium size, and the recommendation for adults is to take two per day. I'm very satisfied with the quality and ingredients.

Heart Attack details

For memory, focus, calm, and POTS, read more in my review. Originally, I bought Alpha GPC because I heard it helps with Huperzine A for POTS, increasing choline, which slows the heart rate and calms an overactive nervous system, a significant issue for those with POTS. I’ve tried various types of choline, but this one works best. It also assists with focus, memory, and sleep. I highly recommend it.

Nausea details

The composition is good, with fast delivery and high-quality, convenient packaging, and nothing was damaged. Although the capsules are slightly large, I have had no issues swallowing them, and they taste citrusy, which I enjoy. I take one capsule daily with meals alongside vitamin D3+K2, magnesium, and vitamin B6. After just 10 days, I’ve noticed significant benefits; my headaches have disappeared, my energy levels have increased, and my mood remains excellent throughout the day. I wholeheartedly recommend it, especially for those interested in sports or following a diet, as omega-3 effectively energises and replenishes what my body needs.

Stroke details

SCIENTIFIC SCORE

Possibly Effective

Based on 4 Researches

alpha-GPC enhances stroke recovery

Barbagallo Sangiorgi G, Barbagallo M, Giordano M, Meli M, Panzarasa R. alpha-Glycerophosphocholine in the mental recovery of cerebral ischemic attacks. An Italian multicenter clinical trial. Ann N Y Acad Sci. 1994;717:253.

We investigated how alpha-glycerophosphocholine (alpha-GPC) can aid in recovery for individuals who have recently suffered strokes or transient ischemic attacks. In this multicenter clinical trial involving 2044 patients, alpha-GPC was given after the event—first through injections for 28 days and then as a daily oral supplement for five months.

Throughout the treatment, we measured cognitive recovery using various scales, including the Mathew Scale, Mini Mental State Test, Crichton Rating Scale, and Global Deterioration Scale. Over the course of just 28 days, patients showed significant improvements in their mental recovery, with the Mathew Scale score increasing by an impressive 15.9 points. By the end of the five-month study, we noticed that many participants achieved near-normal cognitive scores, with 71% experiencing no cognitive decline.

While some patients did report mild adverse effects like heartburn and nausea, the overall tolerability was excellent, with only 2.14% needing to discontinue treatment due to side effects. We learned that alpha-GPC has a promising role in supporting cognitive recovery following strokes and transient ischemic attacks, highlighting its potential benefits in rehabilitation settings.

9.5

Restores recovery

Most Useful Review

An excellent remedy for my seriously ill child, helping to restore memory, speech, and mood. We have seen consistent improvement over 1.5 years. It's particularly beneficial for those recovering from stroke or TBI, with no side effects like headaches.