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NOW Supplements Alpha Lipoic Acid
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.7
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
250 mg
278%
Vitamin E (as d-alpha Tocopheryl Succinate)
20 mg
133%
Alpha Lipoic Acid
100 mg

Top Medical Research Studies

2
Vitamin E links to heart risks
Circulating Vitamin E Levels and Risk of Coronary Artery Disease and Myocardial Infarction: A Mendelian Randomization Study.
Study highlights risks of vitamin E
We explored the relationship between vitamin E and heart attack risk through a two-sample mendelian randomization study. Using genetic variations from nearly 8,000 individuals of European descent, we dug into whether higher levels of vitamin E could protect against coronary artery disease (CAD) and myocardial infarction (MI).

Contrary to some previous beliefs about its benefits, our results suggested that increased vitamin E levels were actually associated with a higher risk of both CAD and MI. This means it's time to rethink the safety and effectiveness of vitamin E supplements for heart health.
Read More
9
Vitamin E reduces heart risks
Vitamin E reduces cardiovascular disease in individuals with diabetes mellitus and the haptoglobin 2-2 genotype.
Highly relevant cardiovascular findings.
We examined how vitamin E affects individuals with diabetes and the specific Haptoglobin 2-2 genotype, who are at greater risk for heart problems. By analyzing data from two trials, we found that taking vitamin E significantly reduced the risk of heart events like strokes and heart attacks in these patients.

The study suggests that screening diabetics for the Haptoglobin genotype and offering vitamin E as treatment could improve heart health and even extend life expectancy by three years for those affected.
Read More
8
Vitamin E reduces heart attack risk
Association between dietary vitamin E intake and incident cardiovascular disease, cardiovascular, and all-cause mortality: A prospective cohort study using NHANES 2003-2018 data.
Study findings are moderately relevant
We explored the effects of dietary vitamin E on heart attack and overall health by analyzing data from over 39,000 participants in the NHANES survey from 2003 to 2018. Our findings indicated that a higher intake of vitamin E was linked to a lower risk of cardiovascular disease and reduced all-cause mortality.

Specifically, those consuming more than 9.86 mg of vitamin E had significantly lower odds of developing cardiovascular issues, including heart attacks. However, the impact on cardiovascular mortality wasn't as strong. This suggests that while vitamin E-rich diets could enhance heart health, further research is necessary for clearer conclusions.
Read More

Most Useful Reviews

8.8
Protects nerves, heart
Very good! My husband and I take alpha lipoic acid every day because, after extensive research, we believe it helps to protect our nerves and heart.
Read More
8.8
Supports heart health
Alpha lipoic acid helps to reduce blood sugar and supports the heart. I enjoy taking it and appreciate the benefits it provides.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.7
  • All Researches
9
Hydrogel with vitamin E aids recovery
Injectable and Conductive Nanomicelle Hydrogel with α-Tocopherol Encapsulation for Enhanced Myocardial Infarction Repair.
Study addresses heart repair issues
We explored how an innovative hydrogel enhanced heart repair after a heart attack. This injectable hydrogel includes α-tocopherol, a form of vitamin E. In our study using a rabbit model, we implanted the hydrogel after inducing a heart attack.

Four weeks later, the results were promising. We noticed improved heart function and reduced damage to heart tissue. This suggests that the hydrogel, enriched with vitamin E, plays a vital role in helping the heart recover better after an injury.
Read More
9
β-Cryptoxanthin outperforming vitamin E
β-Cryptoxanthin exerts greater cardioprotective effects on cardiac ischemia-reperfusion injury than astaxanthin by attenuating mitochondrial dysfunction in mice.
High relevance to heart health
We investigated how three antioxidant compounds—β-cryptoxanthin, astaxanthin, and vitamin E—affect heart damage from ischemia-reperfusion injury in mice.

Mice were treated with these compounds before inducing heart injury.

Results showed that all treatments reduced heart damage, but β-cryptoxanthin was the most effective, shrinking heart injury by 60% compared to vitamin E and astaxanthin.

Ultimately, while vitamin E showed some benefits, β-cryptoxanthin stood out in reducing oxidative stress and cellular damage more effectively.
Read More
9
Vitamin E reduces heart risks
Vitamin E reduces cardiovascular disease in individuals with diabetes mellitus and the haptoglobin 2-2 genotype.
Highly relevant cardiovascular findings.
We examined how vitamin E affects individuals with diabetes and the specific Haptoglobin 2-2 genotype, who are at greater risk for heart problems. By analyzing data from two trials, we found that taking vitamin E significantly reduced the risk of heart events like strokes and heart attacks in these patients.

The study suggests that screening diabetics for the Haptoglobin genotype and offering vitamin E as treatment could improve heart health and even extend life expectancy by three years for those affected.
Read More
9
Combination treatment shows promise
Pretreatment with a combination of quercetin and alpha-tocopherol ameliorates adenosine triphosphatases and lysosomal enzymes in myocardial infarcted rats.
High relevance for cardiac health.
We aimed to explore how a combination of quercetin and vitamin E (alpha-tocopherol) may impact heart function in rats experiencing induced heart attacks. After treatment, all the essential heart enzyme levels returned to normal, suggesting these natural compounds might help stabilize heart membranes and reduce damage.

This is particularly hopeful for patients with heart conditions, as the combination proved to be more effective than either quercetin or vitamin E alone.

However, it’s important to note that while results are promising, further studies are necessary to fully understand these effects in humans.
Read More
8
Vitamin E reduces heart attack risk
Association between dietary vitamin E intake and incident cardiovascular disease, cardiovascular, and all-cause mortality: A prospective cohort study using NHANES 2003-2018 data.
Study findings are moderately relevant
We explored the effects of dietary vitamin E on heart attack and overall health by analyzing data from over 39,000 participants in the NHANES survey from 2003 to 2018. Our findings indicated that a higher intake of vitamin E was linked to a lower risk of cardiovascular disease and reduced all-cause mortality.

Specifically, those consuming more than 9.86 mg of vitamin E had significantly lower odds of developing cardiovascular issues, including heart attacks. However, the impact on cardiovascular mortality wasn't as strong. This suggests that while vitamin E-rich diets could enhance heart health, further research is necessary for clearer conclusions.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8.8
Protects nerves, heart
Very good! My husband and I take alpha lipoic acid every day because, after extensive research, we believe it helps to protect our nerves and heart.
8.8
Supports heart health
Alpha lipoic acid helps to reduce blood sugar and supports the heart. I enjoy taking it and appreciate the benefits it provides.
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