Intragastric infusion of a liquid diet with low-methoxyl pectin alleviates fecal inconsistency and local proinflammatory cytokine expression in lipopolysaccharide-septic rats.
This study aimed to see if low-methoxyl pectin could help manage diarrhea in severely ill patients, particularly those with sepsis. We looked at how pectin affects stool consistency when added to a liquid diet in rats.
Our findings showed that a diet with low-methoxyl pectin resulted in fewer diarrhea episodes and less inflammation. The liquid diet with pectin improved stool texture and reduced inflammatory markers compared to the diet without fiber. Overall, we learned that pectin could be beneficial in managing diarrhea during critical illness.
Read More
9
Probiotic paste aids diarrhea recovery
Efficacy of an orally administered anti-diarrheal probiotic paste (Pro-Kolin Advanced) in dogs with acute diarrhea: A randomized, placebo-controlled, double-blinded clinical study.
We investigated the effects of an oral probiotic paste designed for dogs with acute diarrhea in a well-structured study. Conducted across 14 veterinary clinics, our research found that dogs receiving the probiotic, which contained Enterococcus faecium, experienced significantly faster recovery from diarrhea compared to those receiving a placebo.
Specifically, the duration of diarrhea was shorter, and fewer dogs needed additional medical interventions. This suggests that probiotic treatment can effectively improve outcomes for dogs suffering from acute diarrhea.
Read More
9
Pectin types affect diarrhea control
Undigested low-methoxy pectin prevents diarrhea and induces colonic contraction during liquid-diet feeding in rats.
We explored how various types of pectin in liquid diets could help prevent diarrhea in rats. Through our study, we observed that low-methoxy (LM) and very low-methoxy amidated pectin (VLMA) were effective in forming a gel that held water, resulting in normal feces.
Interestingly, when we removed pectin or calcium from the diets, the rats experienced looser stools and less colonic contraction. This suggests that these types of pectin not only help manage diarrhea but also stimulate the colon's natural movements.
Read More
Most Useful Reviews
9
Balance restored
45 people found this helpful
Truly a miracle. My husband suffers from microscopic colitis, and this product has finally got his system back in balance. For two years, he had daily diarrhoea, and this is the first product to effectively address the issue outside of prescription medication, which only helped temporarily. He plans to continue taking this for several more months at 3 times a day to see what happens. It has been a godsend, and I always trust the NOW brand for good reason.
Read More
9
Prevents discomfort
1 people found this helpful
It is effective and helps me go to the bathroom after eating. There is no diarrhoea or discomfort.
Read More
7.5
Gut regulation achieved
1 people found this helpful
During the usage period, with sufficient water intake, I experienced no constipation. Conversely, as someone prone to diarrhoea, pectin helped regulate my intestines, making my stomach more comfortable and noticeably reducing diarrhoea.
Intragastric infusion of a liquid diet with low-methoxyl pectin alleviates fecal inconsistency and local proinflammatory cytokine expression in lipopolysaccharide-septic rats.
This study aimed to see if low-methoxyl pectin could help manage diarrhea in severely ill patients, particularly those with sepsis. We looked at how pectin affects stool consistency when added to a liquid diet in rats.
Our findings showed that a diet with low-methoxyl pectin resulted in fewer diarrhea episodes and less inflammation. The liquid diet with pectin improved stool texture and reduced inflammatory markers compared to the diet without fiber. Overall, we learned that pectin could be beneficial in managing diarrhea during critical illness.
Read More
9
Pectin aids in managing diarrhea
Effects of enteral nutrition semi-curing feeding on nutritional diarrhoea improvement in the patients with severe stroke.
We explored how enteral nutrition combined with pectin affects diarrhea among stroke patients. In a well-structured study, 60 patients were divided into two groups: one received enteral nutrition with probiotics and pectin, while the other received only probiotics.
Our findings showed that those who received pectin had fewer stools and better overall stool quality within just a few days. Additionally, improvements in nutritional indicators, like serum pre-albumin levels, were notable. This suggests that adding pectin can effectively manage nutritional diarrhea in stroke patients.
Read More
9
Pectin types affect diarrhea control
Undigested low-methoxy pectin prevents diarrhea and induces colonic contraction during liquid-diet feeding in rats.
We explored how various types of pectin in liquid diets could help prevent diarrhea in rats. Through our study, we observed that low-methoxy (LM) and very low-methoxy amidated pectin (VLMA) were effective in forming a gel that held water, resulting in normal feces.
Interestingly, when we removed pectin or calcium from the diets, the rats experienced looser stools and less colonic contraction. This suggests that these types of pectin not only help manage diarrhea but also stimulate the colon's natural movements.
Read More
9
Pectin aids digestive symptom relief
Herbal formula improves upper and lower gastrointestinal symptoms and gut health in Australian adults with digestive disorders.
We explored the effectiveness of the NC Gut Relief Formula, which includes pectin among other ingredients, in improving gastrointestinal symptoms in adults with digestive disorders. Over a 16-week study, participants reported significant reductions in symptoms like indigestion, heartburn, and diarrhea.
Notably, the use of pectin contributed to normalized gut health, as evidenced by improved intestinal permeability and better gut microbiota. Most participants saw improvements in their overall well-being, including mood and energy levels, which highlights pectin's promising role in digestive health.
Read More
9
Probiotic paste aids diarrhea recovery
Efficacy of an orally administered anti-diarrheal probiotic paste (Pro-Kolin Advanced) in dogs with acute diarrhea: A randomized, placebo-controlled, double-blinded clinical study.
We investigated the effects of an oral probiotic paste designed for dogs with acute diarrhea in a well-structured study. Conducted across 14 veterinary clinics, our research found that dogs receiving the probiotic, which contained Enterococcus faecium, experienced significantly faster recovery from diarrhea compared to those receiving a placebo.
Specifically, the duration of diarrhea was shorter, and fewer dogs needed additional medical interventions. This suggests that probiotic treatment can effectively improve outcomes for dogs suffering from acute diarrhea.
Truly a miracle. My husband suffers from microscopic colitis, and this product has finally got his system back in balance. For two years, he had daily diarrhoea, and this is the first product to effectively address the issue outside of prescription medication, which only helped temporarily. He plans to continue taking this for several more months at 3 times a day to see what happens. It has been a godsend, and I always trust the NOW brand for good reason.
Read More
9
Prevents discomfort
1 people found this helpful
It is effective and helps me go to the bathroom after eating. There is no diarrhoea or discomfort.
Read More
7.5
Gut regulation achieved
1 people found this helpful
During the usage period, with sufficient water intake, I experienced no constipation. Conversely, as someone prone to diarrhoea, pectin helped regulate my intestines, making my stomach more comfortable and noticeably reducing diarrhoea.
Read More
9
Notable improvements seen
I have a sensitive stomach and greasy food typically triggers diarrhoea. After trying various probiotics with little effect, apple pectin has significantly improved my condition, and I shall continue its use.
Read More
9
Reduces diarrhea frequency
Worth recommending! After eating a row, my stomach feels good, and I don’t experience frequent diarrhoea. Highly recommended.
Diarrhea is a condition characterized by the frequent passage of loose or watery stools, which can occur due to various factors, including infections, dietary choices, and underlying health conditions. It often results from the body's response to an irritation of the gastrointestinal tract, which can be caused by viruses, bacteria, parasites, or certain medications. While most cases tend to be short-lived and resolve on their own, diarrhea can lead to dehydration, especially in vulnerable populations such as young children and the elderly.
Managing diarrhea typically involves staying hydrated by drinking clear fluids and, when necessary, replenishing lost electrolytes. In some cases, over-the-counter medications may provide relief, although it’s essential to consult a healthcare professional for persistent or severe symptoms. A focus on bland, easy-to-digest foods can also help during recovery. Remember, if diarrhea persists for more than a couple of days or is accompanied by other concerning symptoms—like high fever, severe abdominal pain, or blood in stools—seeking medical attention is crucial.
Pectin is a naturally occurring polysaccharide found in the cell walls of fruits and vegetables, playing a crucial role in their structure and texture. Primarily used as a gelling agent in food preservation, pectin is famous for its ability to form gels when combined with sugar and acid. This makes it an essential ingredient in jams, jellies, and fruit preserves, helping them achieve that desirable thick consistency that many home cooks strive for.
In addition to its culinary uses, pectin is also recognized for its health benefits. It can act as a soluble fiber, potentially aiding in digestive health and helping to regulate blood sugar levels and cholesterol. For those interested in cooking or baking, understanding pectin’s properties can elevate your recipes, allowing you to create a variety of thickened sauces and spreads with the perfect texture. If you’re looking to experiment with pectin in your kitchen, you’ll find it sold in powder or liquid form in grocery stores, often located in the baking aisle.
Pectin, a soluble fiber found in many fruits, can indeed help alleviate diarrhea symptoms. It works by absorbing excess water in the intestines, which helps to firm up loose stools. Pectin also has the ability to form a gel-like substance in the gut, coating the digestive tract and potentially easing irritation. This can be especially beneficial in cases of non-infectious diarrhea, such as that caused by dietary issues or irritable bowel syndrome (IBS).
To incorporate pectin into your diet for diarrhea relief, consider consuming foods rich in this fiber, such as apples, bananas, and citrus fruits, or look for pectin supplements. However, it’s essential to stay hydrated when experiencing diarrhea, as your body loses fluids along with the stool. While pectin can be helpful, it’s advisable to consult a healthcare professional if you have ongoing symptoms or if diarrhea persists for more than a couple of days.
Based on user reviews, the time it typically takes to see results from taking this supplement for diarrhea seems to vary. Many users report experiencing noticeable improvements shortly after starting the supplement, with some indicating relief within a few days or even after the first dose. For instance, one user mentioned that after one capsule at night, their digestive system was functioning well and diarrhea was significantly reduced Read Review. Another user who took two capsules before dinner daily noted significant improvements in gastrointestinal sensitivity and a reduction in diarrhea Read Review.
However, some users implied that longer-term use may be necessary to fully benefit, with one user mentioning that after a few months of use, they noticed improved diarrhea issues Read Review. This suggests that while some may find quick relief, it might take a bit longer for others to achieve optimal results. It's essential to monitor individual responses, as users experienced both improvements and some setbacks, including instances of diarrhea after consumption Read Review.
Scientific research presents mixed results regarding the efficacy of pectin for managing diarrhea. For instance, studies involving mice have demonstrated that pectin from comfrey roots and blueberry pectin can alleviate diarrhea symptoms associated with inflammatory conditions, suggesting potential benefits in similar human cases [1][7]. Furthermore, low-methoxyl pectin has shown promise in critically ill patients by reducing diarrhea episodes and improving stool consistency when included in their liquid diets [2][12].
However, not all studies are in favor of pectin’s effectiveness. A comprehensive review indicated that while some fiber types effectively reduce diarrhea in enteral nutrition, pectin did not show significant improvements [3]. Additionally, a study focusing on children with acute diarrhea found that pectin did not yield notable benefits compared to placebo treatments [14]. These findings highlight that while there may be specific contexts where pectin is beneficial, such as in critically ill patients, its overall reliability as a diarrhea treatment remains uncertain and suggests further research is necessary.
Based on user reviews, many individuals report significant improvements in their symptoms after using this supplement. Users have mentioned that it effectively regulates bowel movements, with one individual noting that taking apple pectin helped them go to the bathroom comfortably after meals without experiencing diarrhea or discomfort Read Review. Another reviewer indicated that apple pectin improved their gastrointestinal sensitivity and noticeably reduced diarrhea after a consistent dosage Read Review.
However, experiences can vary widely. While many users praised it for helping to prevent diarrhea, others reported experiencing diarrhea after consumption, indicating a need for caution Read Review. One review pointed out that after a few months of use alongside probiotics, an improvement in diarrhea symptoms was observed, suggesting that longer-term use might be beneficial for some Read Review. This reflects the idea that individual results can diverge significantly, and what works well for one person may not necessarily yield the same results for another.
Based on user reviews, the combination of this supplement with other supplements, particularly probiotics, appears to yield favorable results for some individuals dealing with diarrhea. One user noted that after using apple pectin alongside probiotics for several months, they observed significant improvements in their diarrhea symptoms, suggesting that the two may work synergistically to enhance digestive health Read Review. Another reviewer mentioned that they experienced better gastrointestinal sensitivity and a reduction in diarrhea by taking two capsules of apple pectin before dinner daily, indicating a more positive outcome when combined with consistent use Read Review.
However, user experiences can vary widely, and some have reported adverse effects, including diarrhea after consumption of the supplement itself, which raises caution Read Review. This divergence in experiences suggests that while the combination of supplements can be beneficial for some, others may not experience the same positive effects, highlighting the importance of personalized approaches in managing gastrointestinal issues.
Based on user reviews, many individuals appear to have found effective doses of pectin for treating diarrhea, pointing to a range of intake methods. Some users reported positive effects after taking one to two capsules daily, often noting improvements in their gastrointestinal health and a reduction in diarrhea symptoms. For instance, one user mentioned that taking two capsules before dinner significantly improved their gastrointestinal sensitivity and reduced diarrhea Read Review. Another user indicated that a single capsule of modified citrus pectin taken at night helped everything function well in their digestive system Read Review.
Conversely, some users did report experiencing diarrhea after consuming pectin, suggesting that individual responses may vary greatly Read Review. While many praised apple pectin for its benefits in stabilizing bowel movements and preventing diarrhea Read ReviewRead Review, it's clear that there is no one-size-fits-all dose, and users may need to experiment with their intake to find what works best for them.
7.5
Best for diarrhea
As the best form of fibre for me, modified citrus pectin helps with diarrhoea effectively. One capsule at night ensures everything is functioning well, while its properties include heavy metal removal, promoting the growth of beneficial bacteria, and lowering cholesterol and sugar levels.
7.5
Significant improvement noted
1 people found this helpful
I take two capsules before dinner daily, which has significantly improved my gastrointestinal sensitivity. My diarrhoea has reduced, and I'm keen to continue taking it and monitoring my body's response.
7.5
Improved diarrhea issue
My mother and her friend purchased apple pectin to use with probiotics. After a few months of use, they noticed an improvement in their diarrhoea issues and will continue to buy it.
0
Caused diarrhoea
Hmm. I experienced diarrhoea when I consumed it.
9
Prevents discomfort
1 people found this helpful
It is effective and helps me go to the bathroom after eating. There is no diarrhoea or discomfort.
7.5
Gut regulation achieved
1 people found this helpful
During the usage period, with sufficient water intake, I experienced no constipation. Conversely, as someone prone to diarrhoea, pectin helped regulate my intestines, making my stomach more comfortable and noticeably reducing diarrhoea.
9
No more diarrhea
3 people found this helpful
I highly recommend this product as it effectively prevents diarrhoea, unlike many other products I've tried. It also helps with constipation.
8
Pectin benefits intestinal health
Pectin from comfrey roots alleviate DSS-induced ulcerative colitis in mice through modulating the intestinal barrier.
We investigated whether pectin from comfrey roots could help manage diarrhea linked to ulcerative colitis caused by sodium dextran sulfate in mice. The results showed that comfrey root pectin alleviated symptoms such as weight loss and diarrhea by improving the intestinal barrier. It also led to better recovery of colon health by influencing certain immune markers and changing the gut microbiome positively. While pectin appears effective in this context, further research is needed to understand its full potential in humans.
8
Pectin complex treatment shows promise
Anti-inflammatory and intestinal microbiota modulation properties of high hydrostatic pressure treated cyanidin-3-glucoside and blueberry pectin complexes on dextran sodium sulfate-induced ulcerative colitis mice.
We explored how treating mice with high hydrostatic pressure (HHP) complexes of cyanidin-3-glucoside and blueberry pectin affected diarrhea linked to ulcerative colitis.
Our findings revealed that these HHP-treated complexes notably reduced diarrhea and blood loss, while also improving colon health in affected mice.
The treatment worked by lowering inflammation markers and enhancing beneficial gut bacteria.
Overall, this study highlights a promising direction for blueberry pectin in managing intestinal issues like diarrhea in colitis.
9
Pectin aids diarrhea management
Intragastric infusion of a liquid diet with low-methoxyl pectin alleviates fecal inconsistency and local proinflammatory cytokine expression in lipopolysaccharide-septic rats.
This study aimed to see if low-methoxyl pectin could help manage diarrhea in severely ill patients, particularly those with sepsis. We looked at how pectin affects stool consistency when added to a liquid diet in rats.
Our findings showed that a diet with low-methoxyl pectin resulted in fewer diarrhea episodes and less inflammation. The liquid diet with pectin improved stool texture and reduced inflammatory markers compared to the diet without fiber. Overall, we learned that pectin could be beneficial in managing diarrhea during critical illness.
7
PCLEN reduces diarrhea in critical care
Pectin-containing liquid enteral nutrition for critical care: a historical control and propensity score matched study.
We examined how pectin-containing liquid enteral nutrition (PCLEN) influences diarrhea in critically ill patients. By comparing 199 patients taking PCLEN with 199 on traditional liquid nutrition (TLEN), we found that PCLEN reduced the rate of diarrhea from 38.2% to 28.1%.
Additionally, it notably lowered the failure rates for enteral nutrition. Even when patients were on gastric acid inhibitors, PCLEN proved effective. Overall, our findings suggest that incorporating pectin might ease some common complications in critical care settings.
7
Fiber type affects diarrhea outcomes
The effect of fiber supplementation on the prevention of diarrhea in hospitalized patients receiving enteral nutrition: A meta-analysis of randomized controlled trials with the GRADE assessment.
We explored whether adding fiber to enteral nutrition can reduce diarrhea in hospitalized patients. After analyzing data from multiple randomized controlled trials, we found that fiber supplements do generally help decrease diarrhea. However, not all types of fiber were equally effective; while partially hydrolyzed guar gum and mixed soluble/insoluble fibers showed positive results, pectin did not have a significant impact. This suggests that fiber type matters when it comes to managing post-feeding diarrhea.
4
Pectin shows no significant benefit
Comparative effectiveness and safety of interventions for acute diarrhea and gastroenteritis in children: A systematic review and network meta-analysis.
We explored the effectiveness of various interventions for acute diarrhea in children, specifically looking at their ability to reduce diarrhea duration. Surprisingly, pectin and other certain treatments, like vitamin A and prebiotics, did not show significant benefits compared to placebo.
Most other interventions, including zinc and loperamide, proved effective, but loperamide also raised safety concerns. Our findings suggest that interventions like pectin may not be beneficial for treating diarrhea, highlighting the need to focus on those that show clear positive results.
References
Liu M, Fu J, Liu Y, Gou W, Yuan W, et al. Pectin from comfrey roots alleviate DSS-induced ulcerative colitis in mice through modulating the intestinal barrier. Int J Biol Macromol. 2024;282:137016. 10.1016/j.ijbiomac.2024.137016
Kagawa T, Yamaoka I. Intragastric infusion of a liquid diet with low-methoxyl pectin alleviates fecal inconsistency and local proinflammatory cytokine expression in lipopolysaccharide-septic rats. Nutrition. 2024;118:112271. 10.1016/j.nut.2023.112271
Kaewdech A, Sripongpun P, Wetwittayakhlang P, Churuangsuk C. The effect of fiber supplementation on the prevention of diarrhea in hospitalized patients receiving enteral nutrition: A meta-analysis of randomized controlled trials with the GRADE assessment. Front Nutr. 2022;9:1008464. 10.3389/fnut.2022.1008464
Hanes D, Nowinski B, Lamb JJ, Larson IA, McDonald D, et al. The gastrointestinal and microbiome impact of a resistant starch blend from potato, banana, and apple fibers: A randomized clinical trial using smart caps. Front Nutr. 2022;9:987216. 10.3389/fnut.2022.987216
Shimizu K, Hirata H, Tokuhira N, Ueda A, Motooka D, et al. A case of massive refractory diarrhea in a patient with COVID-19. Acute Med Surg. 2022;9:e793. 10.1002/ams2.793
Mao HZ, Xiong FT, Hu M, Fu Z. Effects of enteral nutrition semi-curing feeding on nutritional diarrhoea improvement in the patients with severe stroke. Bratisl Lek Listy. 2022;123:214. 10.4149/BLL_2022_035
Tan C, Wang M, Kong Y, Wan M, Deng H, et al. Anti-inflammatory and intestinal microbiota modulation properties of high hydrostatic pressure treated cyanidin-3-glucoside and blueberry pectin complexes on dextran sodium sulfate-induced ulcerative colitis mice. Food Funct. 2022;13:4384. 10.1039/d1fo03376j
Beukema M, Ishisono K, de Waard J, Faas MM, de Vos P, et al. Pectin limits epithelial barrier disruption by Citrobacter rodentium through anti-microbial effects. Food Funct. 2021;12:881. 10.1039/d0fo02605k
Hino K, Miyatake S, Yamada F, Endo N, Akiyama R, et al. Undigested low-methoxy pectin prevents diarrhea and induces colonic contraction during liquid-diet feeding in rats. Nutrition. 2020;78:110804. 10.1016/j.nut.2020.110804
Ried K, Travica N, Dorairaj R, Sali A. Herbal formula improves upper and lower gastrointestinal symptoms and gut health in Australian adults with digestive disorders. Nutr Res. 2020;76:37. 10.1016/j.nutres.2020.02.008
Maruyama M, Goshi S, Kashima Y, Mizuhara A, Higashiguchi T. Clinical Effects of a Pectin-Containing Oligomeric Formula in Tube Feeding Patients: A Multicenter Randomized Clinical Trial. Nutr Clin Pract. 2020;35:464. 10.1002/ncp.10392
Nakamura K, Inokuchi R, Fukushima K, Naraba H, Takahashi Y, et al. Pectin-containing liquid enteral nutrition for critical care: a historical control and propensity score matched study. Asia Pac J Clin Nutr. 2019;28:57. 10.6133/apjcn.201903_28(1).0009
Nixon SL, Rose L, Muller AT. Efficacy of an orally administered anti-diarrheal probiotic paste (Pro-Kolin Advanced) in dogs with acute diarrhea: A randomized, placebo-controlled, double-blinded clinical study. J Vet Intern Med. 2019;33:1286. 10.1111/jvim.15481
Florez ID, Veroniki AA, Al Khalifah R, Yepes-Nuñez JJ, Sierra JM, et al. Comparative effectiveness and safety of interventions for acute diarrhea and gastroenteritis in children: A systematic review and network meta-analysis. PLoS One. 2018;13:e0207701. 10.1371/journal.pone.0207701
Kagawa T, Endo N, Ebisu G, Yamaoka I. Fecal imaging demonstrates that low-methoxyl pectin supplementation normalizes gastro-intestinal transit in mice given a liquid diet. Physiol Rep. 2018;6:e13662. 10.14814/phy2.13662
Tabei I, Tsuchida S, Akashi T, Ookubo K, Hosoda S, et al. Effects of a novel method for enteral nutrition infusion involving a viscosity-regulating pectin solution: A multicenter randomized controlled trial. Clin Nutr ESPEN. 2018;23:34. 10.1016/j.clnesp.2017.11.005