Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 22 Researches
7.7
USERS' SCORE
Moderately Good
Based on 488 Reviews
7.8
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Biotin
1 mg (1,000 mcg)
3333%
Top Medical Research Studies
9
We encountered a case of a woman suffering from short bowel syndrome, who faced significant hair loss due to biotin deficiency while on home parenteral nutrition. After starting oral biotin supplementation of 10 mg/day for three weeks, we observed that her serum biotin levels increased, leading to noticeable new hair growth and resolution of other symptoms. Further intravenous biotin treatment maintained her on multivitamins that include biotin, preventing any future deficiency symptoms. This case highlights the importance of addressing biotin levels for hair health and overall well-being.
9.5
We explored the effects of biotin treatment on hair loss through a case study of a girl diagnosed with biotinidase deficiency. Despite having no notable family history of the condition, her symptoms included problematic dermatitis, yellow hair, and alopecia.
After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.
Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.
After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.
Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.
2
We investigated the effectiveness of biotin as a treatment for hair loss through a literature review focused on available studies. Our search led us to three specific studies that were relevant to the question of whether oral biotin truly supports hair growth or improves hair quality.
One of these studies stood out due to its rigorous design—a double-blind, placebo-controlled trial—but interestingly, it found no significant difference between participants taking biotin and those receiving a placebo when it came to hair growth. The other two studies we examined involved specific groups of patients, such as those on isotretinoin and women who had undergone sleeve gastrectomy. Despite their unique perspectives, these studies were also limited by potential biases and did not provide strong evidence in favor of biotin.
Overall, while biotin has gained immense popularity as a hair supplement among the public, it appears that if one hopes to find robust scientific support for its effectiveness, the evidence is lacking. High-quality research does not substantiate the common belief that biotin can significantly benefit hair health.
One of these studies stood out due to its rigorous design—a double-blind, placebo-controlled trial—but interestingly, it found no significant difference between participants taking biotin and those receiving a placebo when it came to hair growth. The other two studies we examined involved specific groups of patients, such as those on isotretinoin and women who had undergone sleeve gastrectomy. Despite their unique perspectives, these studies were also limited by potential biases and did not provide strong evidence in favor of biotin.
Overall, while biotin has gained immense popularity as a hair supplement among the public, it appears that if one hopes to find robust scientific support for its effectiveness, the evidence is lacking. High-quality research does not substantiate the common belief that biotin can significantly benefit hair health.
Most Useful Reviews
9
Improved hair quality
94 people found this helpful
Biotin (vitamin B7) was recommended to me by an endocrinologist for hair loss. It increases keratin production, and I've also heard many in the gym recommend it during physical exertion. After a month of taking it alongside Omega-3, I have noticed a significant improvement in the quality of my hair. Hair loss has decreased considerably, and my hair is now growing noticeably quicker! The capsules are transparent, allowing me to see the contents.
9
Dramatic reduction
18 people found this helpful
I've experienced hair loss due to stress and poor diet, seeing clumps in the drain. Since starting 4 biotin pills daily alongside pantothenic acid, the hair loss has dramatically reduced in just two weeks. There are now only a few hairs in the drain compared to clumps before. I’m also seeing healthier nails! The difference is quite noticeable.
10
Problem solved
12 people found this helpful
An excellent product! The hair loss problem disappeared entirely. I take one capsule per day in the morning with meals, and this biotin, which comes in a pack of 100 vegetable capsules, has truly worked wonders. Please like this, as I tried very hard to assist you.
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 22 Researches
7.7
- All Researches
9.5
Biotin serum shows promising results
We investigated the effectiveness of the Dr. SKS Hair Booster Serum, which contains biotin and other micronutrients, for treating androgenetic alopecia in both men and women. This open-label study included 1,000 participants across multiple clinics in India who received the serum through mesotherapy or derma roller techniques for six months.
During the study, we closely monitored various indicators of hair health, including the amount of hair loss, hair growth rates, and overall hair density changes. Our findings revealed a significant reduction in hair fall and a notable improvement in hair density after treatment. Interestingly, 95% of participants reported satisfaction with the results after six months.
It’s important to note that while biotin is a key ingredient in the serum, the study did not isolate its effects from the other micronutrients, making it challenging to definitively attribute the positive outcomes solely to biotin. No major adverse effects were reported, suggesting a safe treatment profile.
Overall, the study demonstrated that the Dr. SKS Hair Booster Serum could be a viable option for those struggling with hair loss, providing promising results in the context of androgenetic alopecia.
During the study, we closely monitored various indicators of hair health, including the amount of hair loss, hair growth rates, and overall hair density changes. Our findings revealed a significant reduction in hair fall and a notable improvement in hair density after treatment. Interestingly, 95% of participants reported satisfaction with the results after six months.
It’s important to note that while biotin is a key ingredient in the serum, the study did not isolate its effects from the other micronutrients, making it challenging to definitively attribute the positive outcomes solely to biotin. No major adverse effects were reported, suggesting a safe treatment profile.
Overall, the study demonstrated that the Dr. SKS Hair Booster Serum could be a viable option for those struggling with hair loss, providing promising results in the context of androgenetic alopecia.
9.5
Alopecia areata improvement with tofacitinib
We explored the effectiveness of tofacitinib, a treatment showing promise for alopecia areata (AA), particularly in cases that have proven resistant to other therapies. In one instance, a young adult male with resistant AA had not responded to treatments like oral and topical steroids, minoxidil, and oral troxasalen.
In this study, he received tofacitinib at a dose of 5 mg twice a day along with a biotin supplement. Remarkably, hair regrowth was noted just one month into the treatment, and by the three-month mark, over 90% of his hair had regrown. It’s worth mentioning that no side effects were recorded during the treatment period.
Our findings suggest that while biotin was administered alongside tofacitinib, its specific contributions to hair regrowth outcomes cannot be distinctly isolated. Thus, further research would be necessary to clarify the role of biotin in hair loss treatments.
In this study, he received tofacitinib at a dose of 5 mg twice a day along with a biotin supplement. Remarkably, hair regrowth was noted just one month into the treatment, and by the three-month mark, over 90% of his hair had regrown. It’s worth mentioning that no side effects were recorded during the treatment period.
Our findings suggest that while biotin was administered alongside tofacitinib, its specific contributions to hair regrowth outcomes cannot be distinctly isolated. Thus, further research would be necessary to clarify the role of biotin in hair loss treatments.
9.5
We explored the effects of biotin treatment on hair loss through a case study of a girl diagnosed with biotinidase deficiency. Despite having no notable family history of the condition, her symptoms included problematic dermatitis, yellow hair, and alopecia.
After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.
Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.
After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.
Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.
9
We explored the effectiveness of Dr. SKS Hair Booster Serum, which contains biotin among other ingredients, in treating female pattern hair loss (FPHL) in women diagnosed with polycystic ovary syndrome (PCOS). Our study included 1,000 females aged 25-50 who experienced hair loss classified as Ludwig grades I and II.
Over six months, participants received the serum through injections in the scalp. We employed various assessment techniques, such as photography and microscopic evaluations, to measure changes in hair growth, thickness, and overall health before and after treatment.
After the treatment period, we observed significant improvements in several key hair parameters, including hair shaft diameter and terminal hair counts, as well as a decrease in unwanted hair. Notably, while biotin is a component of the formula, the study could not isolate its specific effects on hair loss due to the combination of multiple active ingredients.
Importantly, no adverse events were reported during the study, suggesting that Dr. SKS Hair Booster Serum is a safe option for those seeking to manage FPHL associated with PCOS. Overall, this study highlights a promising approach to treating hair loss in this specific patient population.
Over six months, participants received the serum through injections in the scalp. We employed various assessment techniques, such as photography and microscopic evaluations, to measure changes in hair growth, thickness, and overall health before and after treatment.
After the treatment period, we observed significant improvements in several key hair parameters, including hair shaft diameter and terminal hair counts, as well as a decrease in unwanted hair. Notably, while biotin is a component of the formula, the study could not isolate its specific effects on hair loss due to the combination of multiple active ingredients.
Importantly, no adverse events were reported during the study, suggesting that Dr. SKS Hair Booster Serum is a safe option for those seeking to manage FPHL associated with PCOS. Overall, this study highlights a promising approach to treating hair loss in this specific patient population.
9
We conducted a study to evaluate how effective biotin, when combined with dexpanthenol injections, is at treating diffuse hair loss. In our research, fifty participants suffering from this condition were divided into two groups to receive six weekly injections of different brands of the treatment—one from Pars Behvarzan and the other from Bayer.
After completing the treatment, we assessed the results through various methods like hair fall counts and hair density tests at one and eight weeks post-treatment. We were pleased to find that both treatments significantly helped in reducing hair loss and improving hair density. Specifically, the hair fall count showed remarkable improvement in both groups, while hair density also saw beneficial changes.
Interestingly, while both treatments were effective, we did notice that the Bayer group had a better improvement in the terminal-to-vellus hair ratio when compared to the Pars group at both follow-ups. Overall, our findings suggest that these injections of biotin and dexpanthenol are effective and safe for individuals experiencing diffuse hair loss, offering a reliable option for those looking to enhance their hair health.
After completing the treatment, we assessed the results through various methods like hair fall counts and hair density tests at one and eight weeks post-treatment. We were pleased to find that both treatments significantly helped in reducing hair loss and improving hair density. Specifically, the hair fall count showed remarkable improvement in both groups, while hair density also saw beneficial changes.
Interestingly, while both treatments were effective, we did notice that the Bayer group had a better improvement in the terminal-to-vellus hair ratio when compared to the Pars group at both follow-ups. Overall, our findings suggest that these injections of biotin and dexpanthenol are effective and safe for individuals experiencing diffuse hair loss, offering a reliable option for those looking to enhance their hair health.
User Reviews
USERS' SCORE
Moderately Good
Based on 488 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improved hair quality
94 people found this helpful
Biotin (vitamin B7) was recommended to me by an endocrinologist for hair loss. It increases keratin production, and I've also heard many in the gym recommend it during physical exertion. After a month of taking it alongside Omega-3, I have noticed a significant improvement in the quality of my hair. Hair loss has decreased considerably, and my hair is now growing noticeably quicker! The capsules are transparent, allowing me to see the contents.
9
Dramatic reduction
18 people found this helpful
I've experienced hair loss due to stress and poor diet, seeing clumps in the drain. Since starting 4 biotin pills daily alongside pantothenic acid, the hair loss has dramatically reduced in just two weeks. There are now only a few hairs in the drain compared to clumps before. I’m also seeing healthier nails! The difference is quite noticeable.
10
Problem solved
12 people found this helpful
An excellent product! The hair loss problem disappeared entirely. I take one capsule per day in the morning with meals, and this biotin, which comes in a pack of 100 vegetable capsules, has truly worked wonders. Please like this, as I tried very hard to assist you.
9
Gorgeous results
7 people found this helpful
An excellent remedy for hair loss! After giving birth, I experienced significant hair loss. On a recommendation, I began taking this supplement alongside omega and vitamins, and the result was stunning. After two weeks, my hair stopped falling out, and new growth appeared in 1.5 months. I suggest a two-month course, repeatable after three months.
9
Quick growth
7 people found this helpful
Great biotin! It has a cumulative effect and doesn't work immediately. The first results can be seen in a month—my hair began to grow quickly, with many new young hairs appearing and reduced hair loss.
Frequently Asked Questions
7.5
Decreased shedding
2 people found this helpful
Good day, I would like to share my experience with vitamin data, which I purchased for my mother due to her hair loss following surgery. Her hair was falling out significantly. After we decided to try biotin at a dosage of 1000mg, we noticed, after about a week, a marked decrease in hair loss. While I cannot confirm new hair growth, I am certain that the shedding has lessened.
7.5
Less hair loss
2 people found this helpful
After drinking biotin for 2 months, my hair loss has decreased. My nails have also become stronger. If you have hair issues, it’s worth trying. I suggest a course of 3 months with a small dosage to start.
9
Quick growth
7 people found this helpful
Great biotin! It has a cumulative effect and doesn't work immediately. The first results can be seen in a month—my hair began to grow quickly, with many new young hairs appearing and reduced hair loss.
9
Gorgeous results
7 people found this helpful
An excellent remedy for hair loss! After giving birth, I experienced significant hair loss. On a recommendation, I began taking this supplement alongside omega and vitamins, and the result was stunning. After two weeks, my hair stopped falling out, and new growth appeared in 1.5 months. I suggest a two-month course, repeatable after three months.
2
We investigated the effectiveness of biotin as a treatment for hair loss through a literature review focused on available studies. Our search led us to three specific studies that were relevant to the question of whether oral biotin truly supports hair growth or improves hair quality.
One of these studies stood out due to its rigorous design—a double-blind, placebo-controlled trial—but interestingly, it found no significant difference between participants taking biotin and those receiving a placebo when it came to hair growth. The other two studies we examined involved specific groups of patients, such as those on isotretinoin and women who had undergone sleeve gastrectomy. Despite their unique perspectives, these studies were also limited by potential biases and did not provide strong evidence in favor of biotin.
Overall, while biotin has gained immense popularity as a hair supplement among the public, it appears that if one hopes to find robust scientific support for its effectiveness, the evidence is lacking. High-quality research does not substantiate the common belief that biotin can significantly benefit hair health.
One of these studies stood out due to its rigorous design—a double-blind, placebo-controlled trial—but interestingly, it found no significant difference between participants taking biotin and those receiving a placebo when it came to hair growth. The other two studies we examined involved specific groups of patients, such as those on isotretinoin and women who had undergone sleeve gastrectomy. Despite their unique perspectives, these studies were also limited by potential biases and did not provide strong evidence in favor of biotin.
Overall, while biotin has gained immense popularity as a hair supplement among the public, it appears that if one hopes to find robust scientific support for its effectiveness, the evidence is lacking. High-quality research does not substantiate the common belief that biotin can significantly benefit hair health.
7
Biotin showed no significant benefits
We explored the effects of biotin on hair growth through a randomized, crossover clinical trial that involved different treatment groups. The trial compared 5% topical minoxidil alone, 5 mg oral biotin alone, and a combination of both treatments to see how they impacted hair growth in men.
Despite the inclusion of biotin in the study, the outcomes did not show a significant benefit for hair growth when biotin was used alone. The results suggest that while topical minoxidil may exhibit effective hair growth stimulation, the isolated effects of oral biotin in conjunction with or without minoxidil warrant further study to clarify its actual role.
Consequently, we can conclude that although biotin is often promoted as a hair growth aid, this particular research did not find strong evidence to support its effectiveness on its own, particularly when compared to the known benefits of topical minoxidil.
Despite the inclusion of biotin in the study, the outcomes did not show a significant benefit for hair growth when biotin was used alone. The results suggest that while topical minoxidil may exhibit effective hair growth stimulation, the isolated effects of oral biotin in conjunction with or without minoxidil warrant further study to clarify its actual role.
Consequently, we can conclude that although biotin is often promoted as a hair growth aid, this particular research did not find strong evidence to support its effectiveness on its own, particularly when compared to the known benefits of topical minoxidil.
7
Biotin's efficacy in combination therapy
We explored the effectiveness of biotin as part of a combination therapy for androgenetic alopecia (AGA) alongside other treatments like Procapil and platelet-rich plasma (PRP). This study was structured as a randomized controlled trial, where we assessed the results among 54 male participants over several sessions.
Participants were divided into two groups: one received Procapil with PRP, while the other received a blend of redensyl, saw palmetto, and biotin with PRP. We closely monitored the changes in hair growth and overall improvement through professional hair photography and grading.
While biotin is a common component in many treatments for hair loss, this study indicates that it may not be effective on its own we reported mixed results regarding the overall benefit of the combination therapies. Our findings suggest that using PRP with redensyl, saw palmetto, and biotin can be a promising alternative, but we can't definitively pinpoint biotin's isolate effects due to its inclusion in a combination treatment.
Participants were divided into two groups: one received Procapil with PRP, while the other received a blend of redensyl, saw palmetto, and biotin with PRP. We closely monitored the changes in hair growth and overall improvement through professional hair photography and grading.
While biotin is a common component in many treatments for hair loss, this study indicates that it may not be effective on its own we reported mixed results regarding the overall benefit of the combination therapies. Our findings suggest that using PRP with redensyl, saw palmetto, and biotin can be a promising alternative, but we can't definitively pinpoint biotin's isolate effects due to its inclusion in a combination treatment.
9.5
We explored the effects of biotin treatment on hair loss through a case study of a girl diagnosed with biotinidase deficiency. Despite having no notable family history of the condition, her symptoms included problematic dermatitis, yellow hair, and alopecia.
After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.
Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.
After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.
Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.
8
Biotin aids hair and skin health
We explored the effects of biotin supplementation in patients undergoing treatment with isotretinoin for acne. In this study, we monitored 60 participants, dividing them into two groups. Both groups received isotretinoin, but one group also took an additional 10 mg of biotin daily. Our goal was to see how this biotin could influence hair health and overall skin condition during treatment.
After four months, we noted significant changes in the group taking biotin. Specifically, the proportion of hair in the anagen (growing) phase increased, while the percentage of hair in the telogen (resting) phase decreased. This suggests that biotin may support hair regrowth during isotretinoin therapy. Additionally, we observed that the skin hydration remained stable in the biotin group, compared to a notable decline in hydration for those not taking the supplement.
Overall, our findings indicate that adding biotin can help mitigate some side effects associated with isotretinoin, especially regarding hair health and skin moisture retention. While it may not be a miracle cure for hair loss, biotin definitely plays a beneficial role in this context.
After four months, we noted significant changes in the group taking biotin. Specifically, the proportion of hair in the anagen (growing) phase increased, while the percentage of hair in the telogen (resting) phase decreased. This suggests that biotin may support hair regrowth during isotretinoin therapy. Additionally, we observed that the skin hydration remained stable in the biotin group, compared to a notable decline in hydration for those not taking the supplement.
Overall, our findings indicate that adding biotin can help mitigate some side effects associated with isotretinoin, especially regarding hair health and skin moisture retention. While it may not be a miracle cure for hair loss, biotin definitely plays a beneficial role in this context.
References
- Yelich A, Jenkins H, Holt S, Miller R. Biotin for Hair Loss: Teasing Out the Evidence. J Clin Aesthet Dermatol. 2024;17:56.
- Qiu S, Pan Z, Jiang X, Lv G, Feng A, et al. The synergistic effect of phototherapy and active substances on hair growth. J Photochem Photobiol B. 2024;259:113008. doi:10.1016/j.jphotobiol.2024.113008
- Valentim FO, Miola AC, Miot HA, Schmitt JV. Efficacy of 5% topical minoxidil versus 5 mg oral biotin versus topical minoxidil and oral biotin on hair growth in men: randomized, crossover, clinical trial. An Bras Dermatol. 2024;99:581. doi:10.1016/j.abd.2023.07.008
- Khare S. Efficacy of Dr. SKS Hair Booster Serum in the Treatment of Female Pattern Alopecia in Patients With PCOS: An Open-Label, Non-randomized, Prospective Study. Cureus. 2023;15:e44941. doi:10.7759/cureus.44941
- Tr P, Ts R, K SK, Prasanna H. A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, and Biotin With Platelet-Rich Plasma Therapy in the Treatment of Androgenetic Alopecia. Cureus. 2023;15:e38696. doi:10.7759/cureus.38696
- Khare S. The Efficacy and Safety of Dr. SKS Hair Booster Serum (a Cocktail of Micronutrients and Multivitamins) in Adult Males and Females With Androgenetic Alopecia: An Open-Label, Non-randomized, Prospective Study. Cureus. 2023;15:e37424. doi:10.7759/cureus.37424
- Sahay G. Resistant Alopecia Areata Treated with Tofacitinib. Int J Trichology. 2022;14:181. doi:10.4103/ijt.ijt_63_22
- Jo H, Kim SY, Kang BH, Baek C, Kwon JE, et al. Cicaria, a Novel Strain Derived from the Human Microbiome, and Its Efficacy as a Treatment for Hair Loss. Molecules. 2022;27. doi:10.3390/molecules27165136
- Samadi A, Ketabi Y, Firooz R, Firooz A. Efficacy of intramuscular injections of biotin and dexpanthenol in the treatment of diffuse hair loss: A randomized, double-blind controlled study comparing two brands. Dermatol Ther. 2022;35:e15695. doi:10.1111/dth.15695
- Starace M, Gurioli C, Carpanese MA, Bruni F, Piraccini BM, et al. Short anagen syndrome: A case series and algorithm for diagnosis. Pediatr Dermatol. 2021;38:1157. doi:10.1111/pde.14750
- Aksac SE, Bilgili SG, Yavuz GO, Yavuz IH, Aksac M, et al. Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters. Int J Dermatol. 2021;60:980. doi:10.1111/ijd.15485
- Yang Y, Yang JY, Chen XJ. Biotinidase deficiency characterized by skin and hair findings. Clin Dermatol. 2020;38:477. doi:10.1016/j.clindermatol.2020.03.004
- Şen O, Türkçapar AG. Hair Loss After Sleeve Gastrectomy and Effect of Biotin Supplements. J Laparoendosc Adv Surg Tech A. 2021;31:296. doi:10.1089/lap.2020.0468
- Marotta JC, Patel G, Carvalho M, Blakeney S. Clinical Efficacy of a Topical Compounded Formulation in Male Androgenetic Alopecia: Minoxidil 10%, Finasteride 0.1%, Biotin 0.2%, and Caffeine Citrate 0.05% Hydroalcoholic Solution. Int J Pharm Compd. 2020;24:69.
- Piraccini BM, Berardesca E, Fabbrocini G, Micali G, Tosti A. Biotin: overview of the treatment of diseases of cutaneous appendages and of hyperseborrhea. G Ital Dermatol Venereol. 2019;154:557. doi:10.23736/S0392-0488.19.06434-4
- Sant'Anna Addor FA, Donato LC, Melo CSA. Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium. Clin Cosmet Investig Dermatol. 2018;11:431. doi:10.2147/CCID.S173082
- Hayashi A, Mikami Y, Miyamoto K, Kamada N, Sato T, et al. Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia through Overgrowth of Lactobacillus murinus in Mice. Cell Rep. 2017;20:1513. doi:10.1016/j.celrep.2017.07.057
- Castro-Gago M, Pérez-Gay L, Gómez-Lado C, Castiñeiras-Ramos DE, Otero-Martínez S, et al. The influence of valproic acid and carbamazepine treatment on serum biotin and zinc levels and on biotinidase activity. J Child Neurol. 2011;26:1522. doi:10.1177/0883073811409227
- Castro-Gago M, Gómez-Lado C, Eirís-Puñal J, Díaz-Mayo I, Castiñeiras-Ramos DE. Serum biotinidase activity in children treated with valproic acid and carbamazepine. J Child Neurol. 2010;25:32. doi:10.1177/0883073809336118
- Schulpis KH, Karikas GA, Tjamouranis J, Regoutas S, Tsakiris S. Low serum biotinidase activity in children with valproic acid monotherapy. Epilepsia. 2001;42:1359.
- Khalidi N, Wesley JR, Thoene JG, Whitehouse WM, Baker WL. Biotin deficiency in a patient with short bowel syndrome during home parenteral nutrition. JPEN J Parenter Enteral Nutr. 1984;8:311.
