Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.3
USERS' SCORE
Good
Based on 43 Reviews
8.7
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Coenzyme Q10 (CoQ10)
100 mg
*
Hawthorn Berry (Crataegus laevigata and/or monogyna) (Fruit)
400 mg
*
Top Medical Research Studies
9
We explored the effects of coenzyme Q10 (CoQ-10) on heart failure (HF) patients by analyzing past literature. Our systematic review examined studies from MEDLINE and the Cochrane Library, focusing on how CoQ-10 influences outcomes like HF-related mortality, exercise capacity, and left ventricular ejection fraction (LVEF).
The results from 16 studies showed some promising findings. CoQ-10 was found to significantly lower HF-related mortality by 40%, which is a notable benefit for patients. Additionally, we observed improvements in exercise capacity for those taking CoQ-10. However, when it came to the impact on LVEF, the results were not statistically significant. While there wasn’t a clear-cut improvement in LVEF, we acknowledge that this aspect needs further exploration to fully understand CoQ-10's potential.
In summary, CoQ-10 appears to be effective in reducing mortality rates and enhancing exercise capacity among heart failure patients. Nonetheless, the effect on LVEF is still uncertain and merits additional investigation.
The results from 16 studies showed some promising findings. CoQ-10 was found to significantly lower HF-related mortality by 40%, which is a notable benefit for patients. Additionally, we observed improvements in exercise capacity for those taking CoQ-10. However, when it came to the impact on LVEF, the results were not statistically significant. While there wasn’t a clear-cut improvement in LVEF, we acknowledge that this aspect needs further exploration to fully understand CoQ-10's potential.
In summary, CoQ-10 appears to be effective in reducing mortality rates and enhancing exercise capacity among heart failure patients. Nonetheless, the effect on LVEF is still uncertain and merits additional investigation.
Read More
9
CoQ10 protects against heart injury
We explored the protective effects of Coenzyme Q10 (CoQ10) and its liposomal form on heart health, particularly in response to copper toxicity caused by copper sulfate (CuSO4). In this study, rats received daily doses of CuSO4 to induce heart injury, while some were also treated with CoQ10 or L-CoQ10 to see if these supplements could mitigate the damage.
The results showed that CuSO4 led to elevated cardiac injury markers and increased oxidative stress, which is known to contribute to heart issues. However, the inclusion of CoQ10 and L-CoQ10 helped lower the levels of harmful markers, improve antioxidant capacity, and reduce inflammation. These supplements effectively restored balance and reduced signs of heart injury, highlighting their potential cardioprotective roles.
Overall, the findings suggest that CoQ10 could serve as a valuable defense for individuals at risk of copper toxicity, reinforcing its relevance in supporting cardiovascular health.
The results showed that CuSO4 led to elevated cardiac injury markers and increased oxidative stress, which is known to contribute to heart issues. However, the inclusion of CoQ10 and L-CoQ10 helped lower the levels of harmful markers, improve antioxidant capacity, and reduce inflammation. These supplements effectively restored balance and reduced signs of heart injury, highlighting their potential cardioprotective roles.
Overall, the findings suggest that CoQ10 could serve as a valuable defense for individuals at risk of copper toxicity, reinforcing its relevance in supporting cardiovascular health.
Read More
9
We explored the effectiveness of coenzyme Q10 in treating heart failure through a thorough analysis of various randomized controlled trials. Our investigation involved a comprehensive search across numerous databases, looking specifically for studies that focused on the impact of coenzyme Q10 on heart failure patients.
The findings were quite promising. We observed that coenzyme Q10 not only reduced the rate of all-cause mortality but also decreased hospitalizations due to heart failure. Improvements were noted in several key health metrics such as the New York Heart Association classification and brain natriuretic peptide levels. Furthermore, participants benefited from enhanced left ventricular ejection fraction and better performance on the six-minute walk test.
Importantly, these benefits were achieved without major adverse effects, suggesting that coenzyme Q10 could be a safe and effective option for those managing heart failure. Overall, our analysis indicates that coenzyme Q10 offers significant advantages for heart failure patients, enhancing their quality of life and potentially extending longevity.
The findings were quite promising. We observed that coenzyme Q10 not only reduced the rate of all-cause mortality but also decreased hospitalizations due to heart failure. Improvements were noted in several key health metrics such as the New York Heart Association classification and brain natriuretic peptide levels. Furthermore, participants benefited from enhanced left ventricular ejection fraction and better performance on the six-minute walk test.
Importantly, these benefits were achieved without major adverse effects, suggesting that coenzyme Q10 could be a safe and effective option for those managing heart failure. Overall, our analysis indicates that coenzyme Q10 offers significant advantages for heart failure patients, enhancing their quality of life and potentially extending longevity.
Read More
Most Useful Reviews
9.5
Elderly essential
Coenzyme Q10 positively affects the heart and helps reduce the risk of cardiovascular disease. As we age, our body’s natural production decreases, leading to serious health issues. It's a crucial supplement for the elderly.
Read More
9.5
Cellular energy supplier
After a month of using this coenzyme, I’m thrilled with the results. Coenzyme Q10 supplies energy to cells, vital for cardiovascular health, while also serving as a strong antioxidant, slowing the ageing process.
Read More
9.5
Cellular energy support
Coenzyme Q10, a vitamin-like compound, plays a vital role in cellular energy production. Its levels drop with age, impacting cardiovascular health. CoQ10 effectively neutralises free radicals, supporting heart, liver, and kidney functions and maintaining cardiovascular health.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.3
- All Researches
9
CoQ10 protects against heart injury
We explored the protective effects of Coenzyme Q10 (CoQ10) and its liposomal form on heart health, particularly in response to copper toxicity caused by copper sulfate (CuSO4). In this study, rats received daily doses of CuSO4 to induce heart injury, while some were also treated with CoQ10 or L-CoQ10 to see if these supplements could mitigate the damage.
The results showed that CuSO4 led to elevated cardiac injury markers and increased oxidative stress, which is known to contribute to heart issues. However, the inclusion of CoQ10 and L-CoQ10 helped lower the levels of harmful markers, improve antioxidant capacity, and reduce inflammation. These supplements effectively restored balance and reduced signs of heart injury, highlighting their potential cardioprotective roles.
Overall, the findings suggest that CoQ10 could serve as a valuable defense for individuals at risk of copper toxicity, reinforcing its relevance in supporting cardiovascular health.
The results showed that CuSO4 led to elevated cardiac injury markers and increased oxidative stress, which is known to contribute to heart issues. However, the inclusion of CoQ10 and L-CoQ10 helped lower the levels of harmful markers, improve antioxidant capacity, and reduce inflammation. These supplements effectively restored balance and reduced signs of heart injury, highlighting their potential cardioprotective roles.
Overall, the findings suggest that CoQ10 could serve as a valuable defense for individuals at risk of copper toxicity, reinforcing its relevance in supporting cardiovascular health.
Read More
9
We explored the effectiveness of coenzyme Q10 in treating heart failure through a thorough analysis of various randomized controlled trials. Our investigation involved a comprehensive search across numerous databases, looking specifically for studies that focused on the impact of coenzyme Q10 on heart failure patients.
The findings were quite promising. We observed that coenzyme Q10 not only reduced the rate of all-cause mortality but also decreased hospitalizations due to heart failure. Improvements were noted in several key health metrics such as the New York Heart Association classification and brain natriuretic peptide levels. Furthermore, participants benefited from enhanced left ventricular ejection fraction and better performance on the six-minute walk test.
Importantly, these benefits were achieved without major adverse effects, suggesting that coenzyme Q10 could be a safe and effective option for those managing heart failure. Overall, our analysis indicates that coenzyme Q10 offers significant advantages for heart failure patients, enhancing their quality of life and potentially extending longevity.
The findings were quite promising. We observed that coenzyme Q10 not only reduced the rate of all-cause mortality but also decreased hospitalizations due to heart failure. Improvements were noted in several key health metrics such as the New York Heart Association classification and brain natriuretic peptide levels. Furthermore, participants benefited from enhanced left ventricular ejection fraction and better performance on the six-minute walk test.
Importantly, these benefits were achieved without major adverse effects, suggesting that coenzyme Q10 could be a safe and effective option for those managing heart failure. Overall, our analysis indicates that coenzyme Q10 offers significant advantages for heart failure patients, enhancing their quality of life and potentially extending longevity.
Read More
9
We explored the effects of coenzyme Q10 (CoQ-10) on heart failure (HF) patients by analyzing past literature. Our systematic review examined studies from MEDLINE and the Cochrane Library, focusing on how CoQ-10 influences outcomes like HF-related mortality, exercise capacity, and left ventricular ejection fraction (LVEF).
The results from 16 studies showed some promising findings. CoQ-10 was found to significantly lower HF-related mortality by 40%, which is a notable benefit for patients. Additionally, we observed improvements in exercise capacity for those taking CoQ-10. However, when it came to the impact on LVEF, the results were not statistically significant. While there wasn’t a clear-cut improvement in LVEF, we acknowledge that this aspect needs further exploration to fully understand CoQ-10's potential.
In summary, CoQ-10 appears to be effective in reducing mortality rates and enhancing exercise capacity among heart failure patients. Nonetheless, the effect on LVEF is still uncertain and merits additional investigation.
The results from 16 studies showed some promising findings. CoQ-10 was found to significantly lower HF-related mortality by 40%, which is a notable benefit for patients. Additionally, we observed improvements in exercise capacity for those taking CoQ-10. However, when it came to the impact on LVEF, the results were not statistically significant. While there wasn’t a clear-cut improvement in LVEF, we acknowledge that this aspect needs further exploration to fully understand CoQ-10's potential.
In summary, CoQ-10 appears to be effective in reducing mortality rates and enhancing exercise capacity among heart failure patients. Nonetheless, the effect on LVEF is still uncertain and merits additional investigation.
Read More
We conducted a thorough investigation into the effects of coenzyme Q10 on cardiovascular health in patients suffering from Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD). In this well-structured study, we utilized a randomized double-blind approach, dividing sixty participants to receive either 240 mg of coenzyme Q10 or a placebo daily for six months.
Our findings revealed that those taking coenzyme Q10 experienced significant improvements in several cardiovascular and liver health markers. Specifically, we noted reduced liver fat and enhanced endothelial function, indicating healthier blood vessels. Measurements showed positive changes in their vascular and myocardial functions, which are critical indicators of heart health.
Conversely, patients in the placebo group did not show any improvement throughout the study period. The results were compelling, underscoring not only the potential of coenzyme Q10 in mitigating liver steatosis but also its role in significantly boosting cardiovascular health.
Overall, by the end of our six-month research period, we observed a marked connection between improvements in liver function and cardiovascular markers, suggesting that coenzyme Q10 might be a beneficial treatment for those grappling with MASLD and associated cardiovascular risks.
Our findings revealed that those taking coenzyme Q10 experienced significant improvements in several cardiovascular and liver health markers. Specifically, we noted reduced liver fat and enhanced endothelial function, indicating healthier blood vessels. Measurements showed positive changes in their vascular and myocardial functions, which are critical indicators of heart health.
Conversely, patients in the placebo group did not show any improvement throughout the study period. The results were compelling, underscoring not only the potential of coenzyme Q10 in mitigating liver steatosis but also its role in significantly boosting cardiovascular health.
Overall, by the end of our six-month research period, we observed a marked connection between improvements in liver function and cardiovascular markers, suggesting that coenzyme Q10 might be a beneficial treatment for those grappling with MASLD and associated cardiovascular risks.
Read More
9
We aimed to understand how Coenzyme Q10 (CoQ10) might help counteract the damage caused by doxorubicin, a common chemotherapy drug known for its harmful side effects on the heart and lungs. To investigate this, we conducted a study involving 27 rats divided into three groups: one group received CoQ10, another received doxorubicin, and the last group received both.
At the end of the study, we examined the hearts and lungs of the rats. Our findings revealed that doxorubicin led to significant harm to the cellular structures in both organs, confirming the drug's cardiotoxic and pulmonary damaging effects. However, when CoQ10 was administered, it showed a promising ability to alleviate these adverse effects, almost restoring the normal appearance of the tissues.
In summary, our study suggests that CoQ10 could act as a protective agent, helping to maintain healthy lung and heart tissues in the context of doxorubicin treatment. This could potentially offer a valuable strategy for enhancing the safety and efficacy of chemotherapy regimens.
At the end of the study, we examined the hearts and lungs of the rats. Our findings revealed that doxorubicin led to significant harm to the cellular structures in both organs, confirming the drug's cardiotoxic and pulmonary damaging effects. However, when CoQ10 was administered, it showed a promising ability to alleviate these adverse effects, almost restoring the normal appearance of the tissues.
In summary, our study suggests that CoQ10 could act as a protective agent, helping to maintain healthy lung and heart tissues in the context of doxorubicin treatment. This could potentially offer a valuable strategy for enhancing the safety and efficacy of chemotherapy regimens.
Read More
User Reviews
USERS' SCORE
Good
Based on 43 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Elderly essential
Coenzyme Q10 positively affects the heart and helps reduce the risk of cardiovascular disease. As we age, our body’s natural production decreases, leading to serious health issues. It's a crucial supplement for the elderly.
Read More
9.5
Cellular energy supplier
After a month of using this coenzyme, I’m thrilled with the results. Coenzyme Q10 supplies energy to cells, vital for cardiovascular health, while also serving as a strong antioxidant, slowing the ageing process.
Read More
9.5
Cellular energy support
Coenzyme Q10, a vitamin-like compound, plays a vital role in cellular energy production. Its levels drop with age, impacting cardiovascular health. CoQ10 effectively neutralises free radicals, supporting heart, liver, and kidney functions and maintaining cardiovascular health.
Read More
9.5
Skin and hair improvement
I took one capsule daily for a month, experiencing enhanced complexion, skin elasticity, and shinier hair. My mother also felt less heart discomfort and lower cholesterol after taking this alongside Omega 3-6-9, supporting our cardiovascular health.
Read More
9.5
Daytime energy boost
A fantastic way to start the day! These capsules are easy to swallow and provide energy by replenishing mitochondria. They also support cardiovascular health. I take two in the morning and feel energised throughout the day.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Alghibiwi HK, Alhusiani AM, Sarawi WS, Fadda L, Alomar HA, et al. Coenzyme Q10 and its liposomal form prevent copper cardiotoxicity by attenuating oxidative stress, TLR-4/NF-κB signaling and necroptosis in rats. Cell Mol Biol (Noisy-le-grand). 2025;71:118. doi:10.14715/cmb/2025.70.1.13
- Zhang M, Sun MY, He WY, Yu SF, Ma WC. [Experimental study on the treatment of diabetic cardiomyopathy in rats by using ultrasound-targeted microbubble destruction combined with coenzyme Q10 loaded long-circulating nanoliposomes]. Zhonghua Yi Xue Za Zhi. 2024;104:3765. doi:10.3760/cma.j.cn112137-20240605-01273
- Xu J, Xiang L, Yin X, Song H, Chen C, et al. Efficacy and safety of coenzyme Q10 in heart failure: a meta-analysis of randomized controlled trials. BMC Cardiovasc Disord. 2024;24:592. doi:10.1186/s12872-024-04232-z
- Qazi SU, Bin Naeem MA, Umar M, Zahid MJ, Kan Changez MI, et al. Evaluating the efficacy of ubiquinol in heart failure patients: a systematic review and meta-analysis. Future Cardiol. 2024;20:221. doi:10.1080/14796678.2024.2352308
- Intan RE, Balti DR, Nugraha RA, Alkaff FF, Salamah S, et al. Angiotensin converting enzyme inhibitor and coenzyme Q10 as adjunctive treatment for patients with ventricular septal rupture following late onset myocardial infarction: a case report. J Pak Med Assoc. 2024;74:S81. doi:10.47391/JPMA.S6-ACSA-16
- Vrentzos E, Ikonomidis I, Pavlidis G, Katogiannis K, Korakas E, et al. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial. Cardiovasc Diabetol. 2024;23:245. doi:10.1186/s12933-024-02326-8
- Ali S, Sulaiman E, Dhiaa S. HISTOLOGICAL EFFECTS OF CO ENZYME Q10 ON DOXORUBICIN-INDUCED DEFICITS OF CARDIOPULMONARY AXIS IN WHITE ALBINO RATS. Georgian Med News. 2024.
- Alehagen U, Aaseth J, Schomburg L, Larsson A, Opstad T, et al. Selenoprotein P increases upon selenium and coenzyme Q supplementation and is associated with telomere length, quality of life and reduced inflammation and mortality. Free Radic Biol Med. 2024;222:403. doi:10.1016/j.freeradbiomed.2024.06.027
- Zeng M, Chen Z, Zhang Y, Pang Y. Combination of trimetazidine and coenzyme Q10 for the treatment of acute viral myocarditis: a systematic review and meta-analysis. J Infect Dev Ctries. 2024;18:658. doi:10.3855/jidc.18776
- Du H, Zhao Y, Wen J, Dai B, Hu G, et al. LncRNA DCRT Protects Against Dilated Cardiomyopathy by Preventing NDUFS2 Alternative Splicing by Binding to PTBP1. Circulation. 2024;150:1030. doi:10.1161/CIRCULATIONAHA.123.067861
