Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.8
Supplement Facts
Serving Size:  3 Veg Capsules
Amount Per Serving
%DV
Calories
5
 
Total Carbohydrate
1.5 g
<1%**
Total Sugars
1.5 g
D-Mannose
1.5 g (1,500 mg)

Top Medical Research Studies

We explored the impact of D-mannose on intervertebral disc degeneration (IVDD), a condition often accompanied by significant pain. The study utilized various sophisticated methods to demonstrate that D-mannose acts primarily through a gene called TXNIP, which influences glutamine metabolism.

Though our findings suggest that D-mannose has promise in alleviating IVDD’s symptoms, we also acknowledge that it has not shown significant pain-relieving effects compared to traditional treatments. Further research may be needed to fully understand its therapeutic potential for pain management.
Read More

Most Useful Reviews

9
Relieves bone pain
4 people found this helpful
After a problematic gynaecological exam in Norway, I developed issues including bone pain and was diagnosed with cystitis. I tried antibiotics, but they only helped temporarily. However, after taking D-Mannose for three days, I could finally sleep through the night without needing to urinate, and after a week, all my symptoms, including the bone pain, vanished. If I stop taking D-Mannose, the symptoms do return.
Read More
9
Bone pain relief
4 people found this helpful
D-Mannose has truly felt like a miracle for my recurrent UTIs, pains, and surgeries I've endured for years. A friend recommended it, and after a few weeks, my symptoms disappeared. I feel more energetic and healthier, which I attribute to the absence of bladder pain. I will definitely keep using this product. Thank you!
Read More
9
Relieved bone pain
2 people found this helpful
I took two capsules three times a day alongside cranberry extract for my lower back pain that troubled me for years. I am very thankful for this product and was pleasantly surprised by the results. I will definitely repeat the course.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
We explored the impact of D-mannose on intervertebral disc degeneration (IVDD), a condition often accompanied by significant pain. The study utilized various sophisticated methods to demonstrate that D-mannose acts primarily through a gene called TXNIP, which influences glutamine metabolism.

Though our findings suggest that D-mannose has promise in alleviating IVDD’s symptoms, we also acknowledge that it has not shown significant pain-relieving effects compared to traditional treatments. Further research may be needed to fully understand its therapeutic potential for pain management.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 11 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Relieves bone pain
4 people found this helpful
After a problematic gynaecological exam in Norway, I developed issues including bone pain and was diagnosed with cystitis. I tried antibiotics, but they only helped temporarily. However, after taking D-Mannose for three days, I could finally sleep through the night without needing to urinate, and after a week, all my symptoms, including the bone pain, vanished. If I stop taking D-Mannose, the symptoms do return.
Read More
9
Bone pain relief
4 people found this helpful
D-Mannose has truly felt like a miracle for my recurrent UTIs, pains, and surgeries I've endured for years. A friend recommended it, and after a few weeks, my symptoms disappeared. I feel more energetic and healthier, which I attribute to the absence of bladder pain. I will definitely keep using this product. Thank you!
Read More
9
Relieved bone pain
2 people found this helpful
I took two capsules three times a day alongside cranberry extract for my lower back pain that troubled me for years. I am very thankful for this product and was pleasantly surprised by the results. I will definitely repeat the course.
Read More
9
Effective for bone pain
1 people found this helpful
This supplement works exceptionally well for bladder pain.
Read More
9
Relieved bone pain
After contracting post-COVID syndrome and battling various ailments, including cystitis, I found no respite from antimicrobials or antibiotics. I turned to Mannose, and within two days, the pain while urinating subsided, and my urges decreased. I also enjoyed a positive effect on my intestines and felt significant relief. I am genuinely satisfied with the results.
Read More

Frequently Asked Questions

9
Relieves bone pain
4 people found this helpful
After a problematic gynaecological exam in Norway, I developed issues including bone pain and was diagnosed with cystitis. I tried antibiotics, but they only helped temporarily. However, after taking D-Mannose for three days, I could finally sleep through the night without needing to urinate, and after a week, all my symptoms, including the bone pain, vanished. If I stop taking D-Mannose, the symptoms do return.
9
Relieved bone pain
After contracting post-COVID syndrome and battling various ailments, including cystitis, I found no respite from antimicrobials or antibiotics. I turned to Mannose, and within two days, the pain while urinating subsided, and my urges decreased. I also enjoyed a positive effect on my intestines and felt significant relief. I am genuinely satisfied with the results.
7
Reduced bone pain
4 people found this helpful
I was thoroughly satisfied with this supplement as it’s made from natural ingredients. I noticed significant benefits, with the frequency of my cystitis episodes decreasing. I took three capsules daily for three months, and the pain that used to plague me once a month has been in remission, which I strongly associate with this supplement.
0
No effect on pain
4 people found this helpful
Unfortunately, D-Mannose has not helped me at all, providing zero relief even for one day. Perhaps it's more effective for someone who does not suffer from chronic cystitis. I've faced persistent issues with E-Coli, and none of my previous treatments, including antibiotics, have worked. I had hoped D-Mannose would help based on positive reviews, but it did not make a difference for me, unlike other herbs.
9
Relieved bone pain
2 people found this helpful
I took two capsules three times a day alongside cranberry extract for my lower back pain that troubled me for years. I am very thankful for this product and was pleasantly surprised by the results. I will definitely repeat the course.
We explored the impact of D-mannose on intervertebral disc degeneration (IVDD), a condition often accompanied by significant pain. The study utilized various sophisticated methods to demonstrate that D-mannose acts primarily through a gene called TXNIP, which influences glutamine metabolism.

Though our findings suggest that D-mannose has promise in alleviating IVDD’s symptoms, we also acknowledge that it has not shown significant pain-relieving effects compared to traditional treatments. Further research may be needed to fully understand its therapeutic potential for pain management.

References

  1. Dong ZL, Jiao X, Wang ZG, Yuan K, Yang YQ, et al. D-mannose alleviates intervertebral disc degeneration through glutamine metabolism. Mil Med Res. 2024;11:28. doi:10.1186/s40779-024-00529-4
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