Last update
3/27/2026
Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Good
Based on 8 Reviews
8.3
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Total Carbohydrate
< 1 g
< 1%**
Echinacea Root (Echinacea purpurea)
800 mg
📅 Last updated:

Top Medical Research Studies

We explored how Echinacea purpurea, a plant commonly used in herbal tea, might help relieve allergies by focusing on its effects on mast cells. Mast cells play a significant role in type-I allergies, such as hay fever, by releasing histamine and leukotrienes—substances that cause allergic symptoms.

Our evaluation involved water extracts from the petals, leaves, and stems of Echinacea purpurea. We specifically looked at how these extracts influenced the release of histamine and other chemical mediators from mast cell lines. The results were quite interesting: both petal and leaf extracts significantly reduced histamine release in stimulated cells. However, the stem extract did not show any effect.

Notably, we found that the petal extract was much more effective than the leaf extract. Additionally, all extracts effectively suppressed leukotriene B4 production, which is another mediator involved in allergic reactions. The petal extract also seemed to decrease certain cellular signaling events associated with mast cell activation.

Overall, our findings suggest that Echinacea purpurea petal extract could potentially help alleviate allergic symptoms, particularly in conditions like hay fever.
Read More
We aimed to investigate how Echinacea, a popular herbal remedy, can help with allergic conditions, particularly asthma. To do this, we isolated the active components from Echinacea purpurea flowers and examined their effects on an animal model mimicking allergic asthma.

Over 14 days, guinea pigs exposed to allergens received a daily dose of Echinacea. Our observations were quite promising; we found significant improvements in airway function, showing that Echinacea could reduce airway resistance and help the muscles in the lungs relax.

Furthermore, we noted its anti-inflammatory effects, which were measured through changes in exhaled nitric oxide levels and cytokine concentrations. These findings suggest that Echinacea could act similarly to conventional asthma medications, reinforcing its place in traditional medicine as a complementary treatment for allergic respiratory issues.
Read More
7
Echinacea shows promise for allergies
We explored the effects of Echinacea purpurea, specifically its root extract and a notable component called dodeca-2E,4E-dienoic acid isobutylamide, on mast cells, which play a crucial role in allergy and inflammation.

In our study, we focused on how these elements influence mast cell activation. By using bone marrow-derived mast cells and a specific mast cell line, we assessed how Echinacea extracts and their alkylamides could potentially inhibit mast cell degranulation and calcium influx, crucial processes in allergic reactions.

The findings indicate that both Echinacea extracts and the alkylamide may serve as remedies for conditions arising from allergic responses. This aligns with the traditional use of Echinacea as an anti-inflammatory treatment, offering a natural approach to remedy allergies.

While further research is needed, these results open the door to considering Echinacea and its constituents as potential candidates for alleviating allergic conditions, thanks to their ability to dampen significant cellular responses in mast cells.
Read More

Most Useful Reviews

9
Good allergy relief
4 people found this helpful
Five Stars. Good relief from allergies.
Read More
9
Reduces allergy issues
Good quality echinacea has significantly lessened my allergy problems. It's great value too.
Read More
7.5
Helps respiratory issues
Echinacea enhances my respiratory health and reduces nasal allergy symptoms.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
  • All Researches
We explored how Echinacea purpurea, a plant commonly used in herbal tea, might help relieve allergies by focusing on its effects on mast cells. Mast cells play a significant role in type-I allergies, such as hay fever, by releasing histamine and leukotrienes—substances that cause allergic symptoms.

Our evaluation involved water extracts from the petals, leaves, and stems of Echinacea purpurea. We specifically looked at how these extracts influenced the release of histamine and other chemical mediators from mast cell lines. The results were quite interesting: both petal and leaf extracts significantly reduced histamine release in stimulated cells. However, the stem extract did not show any effect.

Notably, we found that the petal extract was much more effective than the leaf extract. Additionally, all extracts effectively suppressed leukotriene B4 production, which is another mediator involved in allergic reactions. The petal extract also seemed to decrease certain cellular signaling events associated with mast cell activation.

Overall, our findings suggest that Echinacea purpurea petal extract could potentially help alleviate allergic symptoms, particularly in conditions like hay fever.
Read More
We aimed to investigate how Echinacea, a popular herbal remedy, can help with allergic conditions, particularly asthma. To do this, we isolated the active components from Echinacea purpurea flowers and examined their effects on an animal model mimicking allergic asthma.

Over 14 days, guinea pigs exposed to allergens received a daily dose of Echinacea. Our observations were quite promising; we found significant improvements in airway function, showing that Echinacea could reduce airway resistance and help the muscles in the lungs relax.

Furthermore, we noted its anti-inflammatory effects, which were measured through changes in exhaled nitric oxide levels and cytokine concentrations. These findings suggest that Echinacea could act similarly to conventional asthma medications, reinforcing its place in traditional medicine as a complementary treatment for allergic respiratory issues.
Read More
7
Echinacea shows promise for allergies
We explored the effects of Echinacea purpurea, specifically its root extract and a notable component called dodeca-2E,4E-dienoic acid isobutylamide, on mast cells, which play a crucial role in allergy and inflammation.

In our study, we focused on how these elements influence mast cell activation. By using bone marrow-derived mast cells and a specific mast cell line, we assessed how Echinacea extracts and their alkylamides could potentially inhibit mast cell degranulation and calcium influx, crucial processes in allergic reactions.

The findings indicate that both Echinacea extracts and the alkylamide may serve as remedies for conditions arising from allergic responses. This aligns with the traditional use of Echinacea as an anti-inflammatory treatment, offering a natural approach to remedy allergies.

While further research is needed, these results open the door to considering Echinacea and its constituents as potential candidates for alleviating allergic conditions, thanks to their ability to dampen significant cellular responses in mast cells.
Read More
We explored the effects of echinacea on allergies as part of a broader study on phytotherapy in otorhinolaryngology. This investigation aimed to determine whether echinacea could provide relief for allergy sufferers.

Despite some enthusiasm surrounding herbal remedies, the results showed that there was no significant benefit from using echinacea for allergies. Specifically, while various herbal treatments, including echinacea, had been studied, none produced compelling evidence to support their efficacy in managing allergic conditions.

It's important to note that we need to approach herbal treatments with caution. Although echinacea has its supporters, it seems that its role in alleviating allergy symptoms is not substantiated by strong scientific proof at this time.
Read More

User Reviews

USERS' SCORE
Good
Based on 8 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Good allergy relief
4 people found this helpful
Five Stars. Good relief from allergies.
Read More
9
Reduces allergy issues
Good quality echinacea has significantly lessened my allergy problems. It's great value too.
Read More
7.5
Helps respiratory issues
Echinacea enhances my respiratory health and reduces nasal allergy symptoms.
Read More
7.5
Boosted immunity
It’s a beneficial product for health, particularly in strengthening immunity, maintaining general well-being, and easing allergies.
Read More
7.5
Soothing allergies
A product I use to soothe my allergy symptoms—it's very effective.
Read More

Frequently Asked Questions

7.5
Helps with allergies
Echinacea has greatly assisted with my allergies; my nose no longer runs as much.
9
Reduces allergy issues
Good quality echinacea has significantly lessened my allergy problems. It's great value too.
7.5
Helps respiratory issues
Echinacea enhances my respiratory health and reduces nasal allergy symptoms.
7.5
Immunomodulator benefits
Echinacea acts as a broad-spectrum immunomodulator. I take two capsules daily if I feel unwell, and I have no allergies.
We explored how Echinacea purpurea, a plant commonly used in herbal tea, might help relieve allergies by focusing on its effects on mast cells. Mast cells play a significant role in type-I allergies, such as hay fever, by releasing histamine and leukotrienes—substances that cause allergic symptoms.

Our evaluation involved water extracts from the petals, leaves, and stems of Echinacea purpurea. We specifically looked at how these extracts influenced the release of histamine and other chemical mediators from mast cell lines. The results were quite interesting: both petal and leaf extracts significantly reduced histamine release in stimulated cells. However, the stem extract did not show any effect.

Notably, we found that the petal extract was much more effective than the leaf extract. Additionally, all extracts effectively suppressed leukotriene B4 production, which is another mediator involved in allergic reactions. The petal extract also seemed to decrease certain cellular signaling events associated with mast cell activation.

Overall, our findings suggest that Echinacea purpurea petal extract could potentially help alleviate allergic symptoms, particularly in conditions like hay fever.
7
Echinacea shows promise for allergies
We explored the effects of Echinacea purpurea, specifically its root extract and a notable component called dodeca-2E,4E-dienoic acid isobutylamide, on mast cells, which play a crucial role in allergy and inflammation.

In our study, we focused on how these elements influence mast cell activation. By using bone marrow-derived mast cells and a specific mast cell line, we assessed how Echinacea extracts and their alkylamides could potentially inhibit mast cell degranulation and calcium influx, crucial processes in allergic reactions.

The findings indicate that both Echinacea extracts and the alkylamide may serve as remedies for conditions arising from allergic responses. This aligns with the traditional use of Echinacea as an anti-inflammatory treatment, offering a natural approach to remedy allergies.

While further research is needed, these results open the door to considering Echinacea and its constituents as potential candidates for alleviating allergic conditions, thanks to their ability to dampen significant cellular responses in mast cells.
We explored the effects of echinacea on allergies as part of a broader study on phytotherapy in otorhinolaryngology. This investigation aimed to determine whether echinacea could provide relief for allergy sufferers.

Despite some enthusiasm surrounding herbal remedies, the results showed that there was no significant benefit from using echinacea for allergies. Specifically, while various herbal treatments, including echinacea, had been studied, none produced compelling evidence to support their efficacy in managing allergic conditions.

It's important to note that we need to approach herbal treatments with caution. Although echinacea has its supporters, it seems that its role in alleviating allergy symptoms is not substantiated by strong scientific proof at this time.
We aimed to investigate how Echinacea, a popular herbal remedy, can help with allergic conditions, particularly asthma. To do this, we isolated the active components from Echinacea purpurea flowers and examined their effects on an animal model mimicking allergic asthma.

Over 14 days, guinea pigs exposed to allergens received a daily dose of Echinacea. Our observations were quite promising; we found significant improvements in airway function, showing that Echinacea could reduce airway resistance and help the muscles in the lungs relax.

Furthermore, we noted its anti-inflammatory effects, which were measured through changes in exhaled nitric oxide levels and cytokine concentrations. These findings suggest that Echinacea could act similarly to conventional asthma medications, reinforcing its place in traditional medicine as a complementary treatment for allergic respiratory issues.

References

  1. Zorig A, Toko R, Sukhbold E, Takasugi M, Arai H. Echinacea purpurea water extracts suppress the release of chemical mediators from mast cells. Biosci Biotechnol Biochem. 2021;85:931. 10.1093/bbb/zbaa125
  2. Gulledge TV, Collette NM, Mackey E, Johnstone SE, Moazami Y, et al. Mast cell degranulation and calcium influx are inhibited by an Echinacea purpurea extract and the alkylamide dodeca-2E,4E-dienoic acid isobutylamide. J Ethnopharmacol. 2018;212:166. 10.1016/j.jep.2017.10.012
  3. Laccourreye O, Werner A, Laccourreye L, Bonfils P. Benefits, pitfalls and risks of phytotherapy in clinical practice in otorhinolaryngology. Eur Ann Otorhinolaryngol Head Neck Dis. 2017;134:95. 10.1016/j.anorl.2016.11.001
  4. Šutovská M, Capek P, Kazimierová I, Pappová L, Jošková M, et al. Echinacea complex--chemical view and anti-asthmatic profile. J Ethnopharmacol. 2015;175:163. 10.1016/j.jep.2015.09.007
Data last updated:
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