Dietary consumption of Echinacea by mice afflicted with autoimmune (type I) diabetes: effect of consuming the herb on hemopoietic and immune cell dynamics.
We investigated how Echinacea, a popular herbal remedy known for its immune-boosting properties, affects mice with autoimmune diabetes, specifically using the NOD mouse model that naturally develops Type 1 diabetes. Our focus was on the herb's impact on NK cells—key players in the immune system that are often deficient in this condition.
Through our study, we discovered that feeding Echinacea to these mice resulted in a significant increase in NK cell numbers in both the spleen and the bone marrow. This enhancement occurred regardless of whether the mice received the herb for a short (days) or long (months) period. Additionally, we observed early changes in other immune cell types, suggesting that Echinacea has an immediate, though temporary, effect on immune dynamics.
Importantly, our findings indicate that Echinacea consumption did not lead to any negative effects on the immune or hemopoietic systems in the mice. This consistent increase in NK cells could represent a new avenue for treating Type 1 diabetes, potentially offering a fresh approach to managing this challenging autoimmune disorder.
Read More
9
Echinacea aids autoimmune uveitis control
Oral Echinacea purpurea extract in low-grade, steroid-dependent, autoimmune idiopathic uveitis: a pilot study.
We focused on the potential benefits of Echinacea purpurea, especially for managing low-grade autoimmune uveitis, a condition that can be tough to control with traditional treatments. In our pilot study, we gathered 51 patients with this specific type of uveitis, ensuring that only those with anterior or intermediate forms were included, while exclusion criteria ruled out posterior cases.
Our patients initially received standard treatments, including steroid eye drops and tapered oral prednisone. In addition, 32 of these patients were given Echinacea extract (150 mg twice a day) for further support, while the remaining 20 continued solely on steroids. We found that at the end of a 9-month follow-up, a significant number of the Echinacea group experienced a settlement of their uveitis symptoms, with many able to reduce their steroid use significantly.
Specifically, 19 out of 21 patients with anterior uveitis and 9 out of 11 with intermediate uveitis who took Echinacea benefited from the treatment. Their best-corrected visual acuity also saw improvement or stability. Perhaps reassuringly, we noticed no adverse side effects from the Echinacea, and those on conventional therapy alone required longer steroid treatment, suggesting that Echinacea may serve as an effective complementary therapy in managing this challenging autoimmune disorder.
Read More
5
Echinacea's Effect on Autoimmunity
Review and Assessment of Medicinal Safety Data of Orally Used Echinacea Preparations.
We examined the effects of Echinacea, a plant often turned to for its medicinal properties, specifically regarding its impact on autoimmune disorders. Our analysis highlighted that while there are various preparations of Echinacea, information about their effects on autoimmune conditions can be inconsistent.
Interestingly, some preparations that contain alkamides—certain compounds in Echinacea—showed a potential to suppress certain immune responses, raising questions about the traditional contraindications for their use in autoimmune diseases. Despite some studies indicating that improvements might be observed, the overall evidence does not strongly support significant benefits specifically for treating autoimmune disorders.
We also looked into the safety profile of Echinacea; adverse effects reported were typically mild and without clear evidence of causality. Moreover, long-term studies of up to six months revealed no serious toxicological concerns, suggesting that Echinacea can generally be well-tolerated.
Our journey through the literature led us to conclude that, while Echinacea preparations are popular and generally safe, they may not provide substantial therapeutic benefits specifically for individuals battling autoimmune issues.
Read More
Most Useful Reviews
9
Preventive benefits
6 people found this helpful
I took echinacea for four months last year, two capsules a day, to combat my chronic sinusitis. Previously, I frequently ended up in hospital due to complications from colds or viruses. However, since using echinacea, I have not needed to go back at all. This year, I plan to continue taking it as a preventative measure.
Read More
9
Quick relief
This product is excellent; I noticed the effects quickly. It significantly improved my stomach condition, and I plan to order more.
Read More
7.5
Improved immunity
6 people found this helpful
I have an autoimmune disorder and usually rely on Chinese herbal medicine when unwell. Echinacea seems to enhance my immune function and has helped alleviate my fatigue over the past week. I plan to keep using it to continue feeling better.
We focused on the potential benefits of Echinacea purpurea, especially for managing low-grade autoimmune uveitis, a condition that can be tough to control with traditional treatments. In our pilot study, we gathered 51 patients with this specific type of uveitis, ensuring that only those with anterior or intermediate forms were included, while exclusion criteria ruled out posterior cases.
Our patients initially received standard treatments, including steroid eye drops and tapered oral prednisone. In addition, 32 of these patients were given Echinacea extract (150 mg twice a day) for further support, while the remaining 20 continued solely on steroids. We found that at the end of a 9-month follow-up, a significant number of the Echinacea group experienced a settlement of their uveitis symptoms, with many able to reduce their steroid use significantly.
Specifically, 19 out of 21 patients with anterior uveitis and 9 out of 11 with intermediate uveitis who took Echinacea benefited from the treatment. Their best-corrected visual acuity also saw improvement or stability. Perhaps reassuringly, we noticed no adverse side effects from the Echinacea, and those on conventional therapy alone required longer steroid treatment, suggesting that Echinacea may serve as an effective complementary therapy in managing this challenging autoimmune disorder.
Read More
8
Echinacea boosts NK cells in mice
Dietary consumption of Echinacea by mice afflicted with autoimmune (type I) diabetes: effect of consuming the herb on hemopoietic and immune cell dynamics.
We investigated how Echinacea, a popular herbal remedy known for its immune-boosting properties, affects mice with autoimmune diabetes, specifically using the NOD mouse model that naturally develops Type 1 diabetes. Our focus was on the herb's impact on NK cells—key players in the immune system that are often deficient in this condition.
Through our study, we discovered that feeding Echinacea to these mice resulted in a significant increase in NK cell numbers in both the spleen and the bone marrow. This enhancement occurred regardless of whether the mice received the herb for a short (days) or long (months) period. Additionally, we observed early changes in other immune cell types, suggesting that Echinacea has an immediate, though temporary, effect on immune dynamics.
Importantly, our findings indicate that Echinacea consumption did not lead to any negative effects on the immune or hemopoietic systems in the mice. This consistent increase in NK cells could represent a new avenue for treating Type 1 diabetes, potentially offering a fresh approach to managing this challenging autoimmune disorder.
Read More
5
Echinacea's Effect on Autoimmunity
Review and Assessment of Medicinal Safety Data of Orally Used Echinacea Preparations.
We examined the effects of Echinacea, a plant often turned to for its medicinal properties, specifically regarding its impact on autoimmune disorders. Our analysis highlighted that while there are various preparations of Echinacea, information about their effects on autoimmune conditions can be inconsistent.
Interestingly, some preparations that contain alkamides—certain compounds in Echinacea—showed a potential to suppress certain immune responses, raising questions about the traditional contraindications for their use in autoimmune diseases. Despite some studies indicating that improvements might be observed, the overall evidence does not strongly support significant benefits specifically for treating autoimmune disorders.
We also looked into the safety profile of Echinacea; adverse effects reported were typically mild and without clear evidence of causality. Moreover, long-term studies of up to six months revealed no serious toxicological concerns, suggesting that Echinacea can generally be well-tolerated.
Our journey through the literature led us to conclude that, while Echinacea preparations are popular and generally safe, they may not provide substantial therapeutic benefits specifically for individuals battling autoimmune issues.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 8 Reviews
6.7
All Reviews
Positive Reviews
Negative Reviews
9
Preventive benefits
6 people found this helpful
I took echinacea for four months last year, two capsules a day, to combat my chronic sinusitis. Previously, I frequently ended up in hospital due to complications from colds or viruses. However, since using echinacea, I have not needed to go back at all. This year, I plan to continue taking it as a preventative measure.
Read More
9
Quick relief
This product is excellent; I noticed the effects quickly. It significantly improved my stomach condition, and I plan to order more.
Read More
7.5
Improved immunity
6 people found this helpful
I have an autoimmune disorder and usually rely on Chinese herbal medicine when unwell. Echinacea seems to enhance my immune function and has helped alleviate my fatigue over the past week. I plan to keep using it to continue feeling better.
Read More
7.5
Immunity shield
5 people found this helpful
During cold season, I've ordered echinacea for four years. This brand offers the best value for price and quality. I take two capsules daily for immunity; if I feel unwell, I increase to eight and add vitamin C. While it may not cure infections, it certainly protects me from colds and illnesses.
Read More
2
Caution advised
62 people found this helpful
This herb is not as harmless as it seems. It can cause side effects like low blood pressure and allergies, especially in larger doses. I recommend starting with a small amount to observe your response. While it can boost immunity, if taken excessively, it may deplete the immune system.
An autoimmune disorder occurs when the body's immune system mistakenly attacks its own healthy cells and tissues, believing them to be foreign invaders, such as bacteria or viruses. This reaction can lead to inflammation, tissue damage, and impaired function of the affected organs. There are over 80 known autoimmune diseases, including rheumatoid arthritis, lupus, multiple sclerosis, and type 1 diabetes, each with its own specific symptoms and treatment options. The exact cause of these disorders is still unclear, but a combination of genetic, environmental, and hormonal factors is believed to play a role in their development.
Diagnosis of autoimmune disorders often involves a combination of physical examinations, assessment of symptoms, blood tests, and imaging studies to evaluate organ involvement. Treatment typically focuses on managing symptoms and controlling the immune response using medications such as corticosteroids, immunosuppressants, and biologics. In addition to medication, lifestyle modifications, such as stress management and a balanced diet, can be beneficial in managing symptoms. If you suspect you have an autoimmune condition, it's important to consult a healthcare professional for proper evaluation and tailored treatment options.
Echinacea is a genus of flowering plants in the daisy family, commonly known for its medicinal properties. There are several species within this genus, but Echinacea purpurea is perhaps the most well-known and widely used, particularly in herbal supplements aimed at supporting immune health. Traditionally, Echinacea has been used by Native American tribes for its purported benefits in fighting infections and reducing symptoms of colds and respiratory illnesses. The plant is characterized by its distinctive purple cone-shaped flowers and is also cultivated for ornamental purposes.
In contemporary use, Echinacea is typically available in various forms, including capsules, teas, extracts, and tinctures. While some studies suggest that Echinacea may help reduce the duration and severity of colds when taken at the first signs of illness, evidence remains mixed, and more research is needed to confirm its effectiveness. As always, it’s advisable to consult with a healthcare professional before starting any new supplement, especially for individuals with allergies to plants in the daisy family or those taking specific medications.
Based on user reviews, the timeframe for seeing results from taking echinacea for an autoimmune disorder varies among individuals. One user reported experiencing an improvement in fatigue within just a week of starting the supplement (Read Review). Others recommend using echinacea consistently over a longer period, with another reviewer mentioning they continue taking it for months to prevent illness (Read Review).
Generally, while some users notice effects quickly, others find it beneficial when used regularly over several months. It’s important to consider individual responses, as some may require more time to gauge its full benefits. Therefore, if you're starting echinacea for an autoimmune disorder, be prepared for a range of experiences, and consider a commitment of at least a few weeks to see how it impacts your symptoms.
The evidence supporting the use of Echinacea for autoimmune disorders is mixed. Research evaluating its efficacy indicates some potential benefits, particularly in managing autoimmune uveitis and autoimmune diabetes. In a pilot study, patients suffering from low-grade autoimmune uveitis who received Echinacea experienced significant relief from symptoms and reduced reliance on steroid treatments, suggesting that Echinacea might serve as a beneficial complementary therapy in managing this particular condition [2]. Another study on mice with autoimmune diabetes showed promising results, revealing that Echinacea increased the number of natural killer (NK) cells without adverse effects on the immune system, indicating a potential therapeutic avenue for Type 1 diabetes [3].
However, it's important to note that the findings are not robust across all autoimmune conditions. A review of multiple Echinacea preparations found that while some had immune-suppressing properties, the overall evidence did not provide strong support for significant therapeutic benefits in treating autoimmune disorders [1]. Therefore, while Echinacea may show promise in certain cases, particularly as a complementary therapy, more extensive research is needed to establish its efficacy across a broader range of autoimmune diseases.
Users have reported a variety of improvements in their symptoms after taking echinacea, highlighting its potential as an immune support supplement. A user with chronic sinusitis noted that after four months of use, they avoided hospital visits due to complications from colds or viruses, suggesting a significant preventative effect (Read Review). Another reviewer experienced rapid benefits, claiming improvement in their stomach condition soon after starting the supplement, reinforcing the idea that echinacea may offer quick relief for certain ailments (Read Review).
Additionally, those with autoimmune disorders have found echinacea to enhance immune function and alleviate fatigue, with one user deciding to continue its use for ongoing benefits (Read Review). Other users have reported improvements in throat issues during cold season and a faster recovery from illnesses when combining echinacea with vitamin C (Read Review). It's important to note that individual results can vary, and while many users report positive changes, starting with a lower dose and monitoring one's response is advisable (Read Review).
Users have reported various experiences when combining echinacea with other supplements to address autoimmune disorders. One user found echinacea helpful in enhancing immune function and alleviating fatigue, planning to continue its use for ongoing benefits (Read Review). Another reviewer shared that they typically take echinacea daily but opt to increase their intake to eight capsules when feeling unwell, alongside vitamin C to boost their immunity during cold season, demonstrating a strategic approach to managing their health (Read Review).
Additionally, users have noted improvements in symptoms when echinacea is used in tandem with vitamin C, indicating a combined effect that aids in faster recovery from illnesses (Read Review). However, it's essential for individuals to monitor their responses, as one reviewer cautioned against excessive dosing, which can lead to side effects and may potentially deplete the immune system (Read Review). Overall, users suggest that combining echinacea with vitamin C or increasing its dosage during illness can enhance its protective effects, though individual results may vary.
Based on user reviews, there appears to be a general consensus on the dosing of Echinacea for treating autoimmune disorders, although individual experiences may vary. One user with an autoimmune disorder reported taking two capsules daily, stating it seemed to enhance their immune function and alleviate fatigue (Read Review). Another user, who utilizes Echinacea during cold season, typically takes two capsules daily and has increased that to eight capsules when feeling unwell, indicating a personalized approach based on their condition (Read Review).
While many users found success at lower doses, it’s important to note that some cautioned about potential side effects from larger dosages, suggesting to start small and monitor reactions (Read Review). Furthermore, one user expressed a preference for four doses a day for a more effective immune boost, which highlights the variability in how individuals may reap the benefits of Echinacea (Read Review). Overall, users recommend personalizing the dosage according to individual needs and responses.
7.5
Improved immunity
6 people found this helpful
I have an autoimmune disorder and usually rely on Chinese herbal medicine when unwell. Echinacea seems to enhance my immune function and has helped alleviate my fatigue over the past week. I plan to keep using it to continue feeling better.
9
Preventive benefits
6 people found this helpful
I took echinacea for four months last year, two capsules a day, to combat my chronic sinusitis. Previously, I frequently ended up in hospital due to complications from colds or viruses. However, since using echinacea, I have not needed to go back at all. This year, I plan to continue taking it as a preventative measure.
9
Quick relief
This product is excellent; I noticed the effects quickly. It significantly improved my stomach condition, and I plan to order more.
6
Cold prevention
3 people found this helpful
Echinacea helps me with throat issues when I catch a cold. Since I began taking it, I've avoided serious colds. I don't use it daily to prevent long-term herb intake; I only take it when I feel unwell. Typically, I recover within a day or two, especially with vitamin C.
2
Caution advised
62 people found this helpful
This herb is not as harmless as it seems. It can cause side effects like low blood pressure and allergies, especially in larger doses. I recommend starting with a small amount to observe your response. While it can boost immunity, if taken excessively, it may deplete the immune system.
7.5
Immunity shield
5 people found this helpful
During cold season, I've ordered echinacea for four years. This brand offers the best value for price and quality. I take two capsules daily for immunity; if I feel unwell, I increase to eight and add vitamin C. While it may not cure infections, it certainly protects me from colds and illnesses.
6
Strengthened immunity
I find this form of echinacea much more effective. I take it four times a day to bolster my immune system.
9
Echinacea aids autoimmune uveitis control
Oral Echinacea purpurea extract in low-grade, steroid-dependent, autoimmune idiopathic uveitis: a pilot study.
We focused on the potential benefits of Echinacea purpurea, especially for managing low-grade autoimmune uveitis, a condition that can be tough to control with traditional treatments. In our pilot study, we gathered 51 patients with this specific type of uveitis, ensuring that only those with anterior or intermediate forms were included, while exclusion criteria ruled out posterior cases.
Our patients initially received standard treatments, including steroid eye drops and tapered oral prednisone. In addition, 32 of these patients were given Echinacea extract (150 mg twice a day) for further support, while the remaining 20 continued solely on steroids. We found that at the end of a 9-month follow-up, a significant number of the Echinacea group experienced a settlement of their uveitis symptoms, with many able to reduce their steroid use significantly.
Specifically, 19 out of 21 patients with anterior uveitis and 9 out of 11 with intermediate uveitis who took Echinacea benefited from the treatment. Their best-corrected visual acuity also saw improvement or stability. Perhaps reassuringly, we noticed no adverse side effects from the Echinacea, and those on conventional therapy alone required longer steroid treatment, suggesting that Echinacea may serve as an effective complementary therapy in managing this challenging autoimmune disorder.
8
Echinacea boosts NK cells in mice
Dietary consumption of Echinacea by mice afflicted with autoimmune (type I) diabetes: effect of consuming the herb on hemopoietic and immune cell dynamics.
We investigated how Echinacea, a popular herbal remedy known for its immune-boosting properties, affects mice with autoimmune diabetes, specifically using the NOD mouse model that naturally develops Type 1 diabetes. Our focus was on the herb's impact on NK cells—key players in the immune system that are often deficient in this condition.
Through our study, we discovered that feeding Echinacea to these mice resulted in a significant increase in NK cell numbers in both the spleen and the bone marrow. This enhancement occurred regardless of whether the mice received the herb for a short (days) or long (months) period. Additionally, we observed early changes in other immune cell types, suggesting that Echinacea has an immediate, though temporary, effect on immune dynamics.
Importantly, our findings indicate that Echinacea consumption did not lead to any negative effects on the immune or hemopoietic systems in the mice. This consistent increase in NK cells could represent a new avenue for treating Type 1 diabetes, potentially offering a fresh approach to managing this challenging autoimmune disorder.
5
Echinacea's Effect on Autoimmunity
Review and Assessment of Medicinal Safety Data of Orally Used Echinacea Preparations.
We examined the effects of Echinacea, a plant often turned to for its medicinal properties, specifically regarding its impact on autoimmune disorders. Our analysis highlighted that while there are various preparations of Echinacea, information about their effects on autoimmune conditions can be inconsistent.
Interestingly, some preparations that contain alkamides—certain compounds in Echinacea—showed a potential to suppress certain immune responses, raising questions about the traditional contraindications for their use in autoimmune diseases. Despite some studies indicating that improvements might be observed, the overall evidence does not strongly support significant benefits specifically for treating autoimmune disorders.
We also looked into the safety profile of Echinacea; adverse effects reported were typically mild and without clear evidence of causality. Moreover, long-term studies of up to six months revealed no serious toxicological concerns, suggesting that Echinacea can generally be well-tolerated.
Our journey through the literature led us to conclude that, while Echinacea preparations are popular and generally safe, they may not provide substantial therapeutic benefits specifically for individuals battling autoimmune issues.
References
Ardjomand-Woelkart K, Bauer R. Review and Assessment of Medicinal Safety Data of Orally Used Echinacea Preparations. Planta Med. 2016;82:17. 10.1055/s-0035-1558096
Neri PG, Stagni E, Filippello M, Camillieri G, Giovannini A, et al. Oral Echinacea purpurea extract in low-grade, steroid-dependent, autoimmune idiopathic uveitis: a pilot study. J Ocul Pharmacol Ther. 2006;22:431.
Delorme D, Miller SC. Dietary consumption of Echinacea by mice afflicted with autoimmune (type I) diabetes: effect of consuming the herb on hemopoietic and immune cell dynamics. Autoimmunity. 2005;38:453.