We observed the effectiveness of Rebixiao granules, which include niacin, in treating patients with repeatedly attacking acute gouty arthritis. In the study, 90 patients were split into two groups. The first group received Rebixiao granule treatment, while the second group was given traditional anti-inflammatory tablets. Both groups also followed standard treatments like dietary changes and hydration.
One interesting aspect was the animal study that involved administering hypoxanthine and niacin to mice. This helped establish a model to see how these treatments affected uric acid levels in the blood. The results showed that Rebixiao granules were effective at reducing blood uric acid and had quicker results than just anti-inflammatory treatments alone. However, while niacin was part of the treatment, the study does not clarify its isolated impact on gout as it was combined with other ingredients.
Overall, we found that Rebixiao granules, possibly aided by niacin, were beneficial for gout patients without significant side effects. This indicates a promising option for managing gout symptoms and preventing future attacks.
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