' 
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 46 Reviews
8.9
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Inositol
500 mg
**
Top Medical Research Studies
9
SCI offers safe anticoagulant potential
A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
Highly relevant to anticoagulant development
We explored the effects of a synthetic heparin mimetic known as sulfated chiro-inositol (SCI) on blood clotting mechanisms. This innovative treatment aims to inhibit human factor XIa (FXIa), a key player in the clotting process, while minimizing bleeding risks typically associated with anticoagulants.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
Read More
Most Useful Reviews
9
Thins blood effectively
Inositol is a vitamin-like substance, a soluble alcohol that normalises the digestive tract, lowers blood pressure, and blood sugar. It activates lipid metabolism, maintains the elasticity of blood vessel walls, thins the blood, and prevents the formation of blood clots. I highly recommend it.
Read More
9.5
Prevents blood clots
Wonderful Inositol is a soluble alcohol that normalises the digestive system, reduces blood pressure, and lowers blood sugar. It activates lipid metabolism, maintains the elasticity of blood vessel walls, thins the blood, and prevents the formation of blood clots. I took it alongside 5-HTP for better absorption.
Read More
9.5
Good combination for health
Inositol is a soluble alcohol that aids in normalising digestion, lowering blood pressure and sugar levels, and preventing blood clots. I took it alongside 5-HTP for better absorption and found the capsules easy to swallow. Shopping was a pleasant experience, and I felt several health benefits.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
SCI offers safe anticoagulant potential
A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
Highly relevant to anticoagulant development
We explored the effects of a synthetic heparin mimetic known as sulfated chiro-inositol (SCI) on blood clotting mechanisms. This innovative treatment aims to inhibit human factor XIa (FXIa), a key player in the clotting process, while minimizing bleeding risks typically associated with anticoagulants.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
Read More
User Reviews
USERS' SCORE
Good
Based on 46 Reviews
8.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
Thins blood effectively
Inositol is a vitamin-like substance, a soluble alcohol that normalises the digestive tract, lowers blood pressure, and blood sugar. It activates lipid metabolism, maintains the elasticity of blood vessel walls, thins the blood, and prevents the formation of blood clots. I highly recommend it.
Read More
9.5
Prevents blood clots
Wonderful Inositol is a soluble alcohol that normalises the digestive system, reduces blood pressure, and lowers blood sugar. It activates lipid metabolism, maintains the elasticity of blood vessel walls, thins the blood, and prevents the formation of blood clots. I took it alongside 5-HTP for better absorption.
Read More
9.5
Good combination for health
Inositol is a soluble alcohol that aids in normalising digestion, lowering blood pressure and sugar levels, and preventing blood clots. I took it alongside 5-HTP for better absorption and found the capsules easy to swallow. Shopping was a pleasant experience, and I felt several health benefits.
Read More
9.5
Prevents blood clots
Inositol is known as the “vitamin of youth” because it aids in fat metabolism, lowers cholesterol levels in the blood, and thereby reduces the risk of developing atherosclerosis and obesity. Vitamin B8 also enhances blood flow, prevents blood clot formation, and helps maintain the elasticity of artery walls.
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9.5
Helpful for fertility
Life-changing! After a few months on inositol, I noticed a difference with my PCOS symptoms—weight loss and blood sugar regulation. After being infertile for 2.5 years, I fell pregnant shortly after starting this. It truly assists women with fertility challenges, more so than metformin with its side effects.
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