' 
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.6
USERS' SCORE
Good
Based on 1 Review
8.6
Supplement Facts
Serving Size: About 1/4 cup (31 g)
Amount Per Serving
%DV
Calories
180
Total Fat
13 g
17%
Saturated Fat
3 g
15%
Trans Fat
0 g
Cholesterol
0 mg
0%
Sodium
0 mg
0%
Total Carbohydrate
4 g
1%
Dietary Fiber
2 g
7%
Total Sugars
0 g
Includes 0g Added Sugars
0%
Protein
11g
Vit. D
0 mcg
0%
Calcium
8 mg
0%
Iron
4 mg
20%
Potassium
243 mg
6%
Top Medical Research Studies
9
Promising peptides for acne treatment
Novel-designed antimicrobial peptides with dual antimicrobial and anti-inflammatory actions against Cutibacterium acnes for acne vulgaris therapy.
High relevance to acne treatment
We explored the potential of novel antimicrobial peptides (AMPs) designed to combat acne vulgaris, a common skin issue caused by the bacteria Cutibacterium acnes. Traditional treatments often lead to antibiotic resistance and unwanted side effects, prompting the need for alternative solutions.
Our approach involved creating short peptides made up of 13 amino acids. We specifically tweaked these peptides by adjusting the number and position of tryptophan residues to enhance their effectiveness. Among the various peptides synthesized, we found that DAP-7 and DAP-10 stood out for their strong antimicrobial properties against both antibiotic-sensitive and -resistant strains of C. acnes, while causing minimal damage to human cells.
By targeting the bacterial membrane, these peptides can disrupt the bacteria, leading to their breakdown. Additionally, DAP-7 and DAP-10 were effective in reducing the levels of inflammation linked to acne. Remarkably, DAP-7 resulted not only in fewer C. acnes colonies but also significantly decreased swelling in a mouse model of acne.
Our findings indicate that DAP-7 and DAP-10 are promising options for developing new acne treatments, offering a dual action that tackles both the bacteria and the associated inflammation.
Our approach involved creating short peptides made up of 13 amino acids. We specifically tweaked these peptides by adjusting the number and position of tryptophan residues to enhance their effectiveness. Among the various peptides synthesized, we found that DAP-7 and DAP-10 stood out for their strong antimicrobial properties against both antibiotic-sensitive and -resistant strains of C. acnes, while causing minimal damage to human cells.
By targeting the bacterial membrane, these peptides can disrupt the bacteria, leading to their breakdown. Additionally, DAP-7 and DAP-10 were effective in reducing the levels of inflammation linked to acne. Remarkably, DAP-7 resulted not only in fewer C. acnes colonies but also significantly decreased swelling in a mouse model of acne.
Our findings indicate that DAP-7 and DAP-10 are promising options for developing new acne treatments, offering a dual action that tackles both the bacteria and the associated inflammation.
Read More
8
Identifying proteins linked to acne
Unveiling new protein biomarkers and therapeutic targets for acne through integrated analysis of human plasma proteomics and genomics.
Significant findings on acne treatment
We investigated how specific proteins influence the development of acne by analyzing extensive data from a large cohort. In a study involving over 54,000 participants, we examined the relationship between nearly 3,000 serum proteins and the onset of acne.
Our analysis revealed 19 proteins significantly linked to acne risk. Among these, two proteins stood out—FSTL1 and ANXA5. We found that higher levels of these proteins were associated with an increased likelihood of developing acne, with each one-standard deviation rise corresponding to a 24% and 32% increase in acne incidence, respectively.
Using advanced genetic analysis methods, we confirmed these findings and suggested that these proteins could be valuable targets for new acne treatments. This work highlights the potential for protein-based approaches in tackling acne effectively.
Our analysis revealed 19 proteins significantly linked to acne risk. Among these, two proteins stood out—FSTL1 and ANXA5. We found that higher levels of these proteins were associated with an increased likelihood of developing acne, with each one-standard deviation rise corresponding to a 24% and 32% increase in acne incidence, respectively.
Using advanced genetic analysis methods, we confirmed these findings and suggested that these proteins could be valuable targets for new acne treatments. This work highlights the potential for protein-based approaches in tackling acne effectively.
Read More
9
Peptide combination enhances acne treatment
The combination of RL-QN15 and OH-CATH30 promotes the repair of acne via the TLR2/NF-κB pathway.
Combination treatment shows promise
We investigated the impact of two peptides, RL-QN15 and OH-CATH30, on treating acne in mice. Our findings revealed that when applied together, these peptides significantly reduced the growth of Propionibacterium acnes, the bacteria responsible for acne, and decreased the associated swelling.
Alongside tackling the bacteria, this combination also helped lower the production of inflammatory molecules, such as IL-1β and TNF-α, which are known to worsen acne condition. Notably, the treatment encouraged collagen production, promoting better skin repair and healing.
From a biological standpoint, we learned that RL-QN15 and OH-CATH30 work by suppressing the toll-like receptor 2 (TLR2) and the NF-κB signaling pathway, which ultimately reduces inflammation and aids in skin recovery. This points to their potential as a promising strategy for acne therapy, emphasizing the importance of looking at innovative protein combinations.
Overall, our study highlights a new, effective approach in tackling the persistent issue of acne. By focusing on these combined proteins, we are paving the way for advanced treatment options that could significantly improve the quality of life for those suffering from this common skin condition.
Alongside tackling the bacteria, this combination also helped lower the production of inflammatory molecules, such as IL-1β and TNF-α, which are known to worsen acne condition. Notably, the treatment encouraged collagen production, promoting better skin repair and healing.
From a biological standpoint, we learned that RL-QN15 and OH-CATH30 work by suppressing the toll-like receptor 2 (TLR2) and the NF-κB signaling pathway, which ultimately reduces inflammation and aids in skin recovery. This points to their potential as a promising strategy for acne therapy, emphasizing the importance of looking at innovative protein combinations.
Overall, our study highlights a new, effective approach in tackling the persistent issue of acne. By focusing on these combined proteins, we are paving the way for advanced treatment options that could significantly improve the quality of life for those suffering from this common skin condition.
Read More
Most Useful Reviews
9.5
Heals acne scars
GREAT FOR HAIR AND SKIN. I absolutely adore these! I take several daily, and it has significantly improved my very damaged hair while also helping to reduce the acne scarring on my face.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.6
9
Afzelin reduces acne inflammation
Effect of afzelin on inflammation and lipogenesis in particulate matter-stimulated treated SZ95 sebocytes.
Study highlights protein's limited impact
We focused on exploring how afzelin, a natural flavonoid known for its anti-inflammatory effects, influences acne-related inflammation and sebum production in a specific type of skin cell called SZ95 sebocytes. To set the stage for our investigation, we simulated an acne-like condition by introducing heat-killed bacteria into the cells, along with exposure to particulate matter (PM).
We observed that PM may worsen acne by increasing inflammatory responses and promoting sebum secretion. Excitingly, when we treated these cells with afzelin, we found that it significantly reduced the inflammatory cytokine levels and inhibited the processes that lead to excess oil production. This suggests that afzelin could serve as a beneficial treatment option for alleviating PM-related acne.
Overall, our findings highlight the dual role of afzelin in combating acne by addressing both inflammation and sebum overproduction, positioning it as a potential therapeutic agent in skincare treatments.
We observed that PM may worsen acne by increasing inflammatory responses and promoting sebum secretion. Excitingly, when we treated these cells with afzelin, we found that it significantly reduced the inflammatory cytokine levels and inhibited the processes that lead to excess oil production. This suggests that afzelin could serve as a beneficial treatment option for alleviating PM-related acne.
Overall, our findings highlight the dual role of afzelin in combating acne by addressing both inflammation and sebum overproduction, positioning it as a potential therapeutic agent in skincare treatments.
Read More
9
Peptide combination enhances acne treatment
The combination of RL-QN15 and OH-CATH30 promotes the repair of acne via the TLR2/NF-κB pathway.
Combination treatment shows promise
We investigated the impact of two peptides, RL-QN15 and OH-CATH30, on treating acne in mice. Our findings revealed that when applied together, these peptides significantly reduced the growth of Propionibacterium acnes, the bacteria responsible for acne, and decreased the associated swelling.
Alongside tackling the bacteria, this combination also helped lower the production of inflammatory molecules, such as IL-1β and TNF-α, which are known to worsen acne condition. Notably, the treatment encouraged collagen production, promoting better skin repair and healing.
From a biological standpoint, we learned that RL-QN15 and OH-CATH30 work by suppressing the toll-like receptor 2 (TLR2) and the NF-κB signaling pathway, which ultimately reduces inflammation and aids in skin recovery. This points to their potential as a promising strategy for acne therapy, emphasizing the importance of looking at innovative protein combinations.
Overall, our study highlights a new, effective approach in tackling the persistent issue of acne. By focusing on these combined proteins, we are paving the way for advanced treatment options that could significantly improve the quality of life for those suffering from this common skin condition.
Alongside tackling the bacteria, this combination also helped lower the production of inflammatory molecules, such as IL-1β and TNF-α, which are known to worsen acne condition. Notably, the treatment encouraged collagen production, promoting better skin repair and healing.
From a biological standpoint, we learned that RL-QN15 and OH-CATH30 work by suppressing the toll-like receptor 2 (TLR2) and the NF-κB signaling pathway, which ultimately reduces inflammation and aids in skin recovery. This points to their potential as a promising strategy for acne therapy, emphasizing the importance of looking at innovative protein combinations.
Overall, our study highlights a new, effective approach in tackling the persistent issue of acne. By focusing on these combined proteins, we are paving the way for advanced treatment options that could significantly improve the quality of life for those suffering from this common skin condition.
Read More
9
Promising peptides for acne treatment
Novel-designed antimicrobial peptides with dual antimicrobial and anti-inflammatory actions against Cutibacterium acnes for acne vulgaris therapy.
High relevance to acne treatment
We explored the potential of novel antimicrobial peptides (AMPs) designed to combat acne vulgaris, a common skin issue caused by the bacteria Cutibacterium acnes. Traditional treatments often lead to antibiotic resistance and unwanted side effects, prompting the need for alternative solutions.
Our approach involved creating short peptides made up of 13 amino acids. We specifically tweaked these peptides by adjusting the number and position of tryptophan residues to enhance their effectiveness. Among the various peptides synthesized, we found that DAP-7 and DAP-10 stood out for their strong antimicrobial properties against both antibiotic-sensitive and -resistant strains of C. acnes, while causing minimal damage to human cells.
By targeting the bacterial membrane, these peptides can disrupt the bacteria, leading to their breakdown. Additionally, DAP-7 and DAP-10 were effective in reducing the levels of inflammation linked to acne. Remarkably, DAP-7 resulted not only in fewer C. acnes colonies but also significantly decreased swelling in a mouse model of acne.
Our findings indicate that DAP-7 and DAP-10 are promising options for developing new acne treatments, offering a dual action that tackles both the bacteria and the associated inflammation.
Our approach involved creating short peptides made up of 13 amino acids. We specifically tweaked these peptides by adjusting the number and position of tryptophan residues to enhance their effectiveness. Among the various peptides synthesized, we found that DAP-7 and DAP-10 stood out for their strong antimicrobial properties against both antibiotic-sensitive and -resistant strains of C. acnes, while causing minimal damage to human cells.
By targeting the bacterial membrane, these peptides can disrupt the bacteria, leading to their breakdown. Additionally, DAP-7 and DAP-10 were effective in reducing the levels of inflammation linked to acne. Remarkably, DAP-7 resulted not only in fewer C. acnes colonies but also significantly decreased swelling in a mouse model of acne.
Our findings indicate that DAP-7 and DAP-10 are promising options for developing new acne treatments, offering a dual action that tackles both the bacteria and the associated inflammation.
Read More
8
Combination therapy improves acne scars
Treatment of acne scars using subcision combined with concentrated growth factors versus subcision monotherapy: a retrospective cohort study.
Partially relevant to protein effects
We evaluated the effectiveness of combining concentrated growth factors (CGF) with subcision, a surgical option commonly used to improve acne scars. In our study, sixty patients with noticeable acne scars were treated with either the combination therapy of subcision and CGF or subcision alone.
After analyzing the results, we found that both treatment options led to significant improvements in the appearance of scars. However, those who received the combination of CGF and subcision experienced greater reductions in their scars' severity, as reflected in patient satisfaction scores.
It's worth noting that this combination approach appeared to be safe, with only minor side effects like increased bruising and pain, both of which were temporary and resolved in a reasonable time frame. Overall, integrating CGF with subcision could provide more effective results for treating severe acne scars, offering patients a promising option for clearer skin.
After analyzing the results, we found that both treatment options led to significant improvements in the appearance of scars. However, those who received the combination of CGF and subcision experienced greater reductions in their scars' severity, as reflected in patient satisfaction scores.
It's worth noting that this combination approach appeared to be safe, with only minor side effects like increased bruising and pain, both of which were temporary and resolved in a reasonable time frame. Overall, integrating CGF with subcision could provide more effective results for treating severe acne scars, offering patients a promising option for clearer skin.
Read More
8
Identifying proteins linked to acne
Unveiling new protein biomarkers and therapeutic targets for acne through integrated analysis of human plasma proteomics and genomics.
Significant findings on acne treatment
We investigated how specific proteins influence the development of acne by analyzing extensive data from a large cohort. In a study involving over 54,000 participants, we examined the relationship between nearly 3,000 serum proteins and the onset of acne.
Our analysis revealed 19 proteins significantly linked to acne risk. Among these, two proteins stood out—FSTL1 and ANXA5. We found that higher levels of these proteins were associated with an increased likelihood of developing acne, with each one-standard deviation rise corresponding to a 24% and 32% increase in acne incidence, respectively.
Using advanced genetic analysis methods, we confirmed these findings and suggested that these proteins could be valuable targets for new acne treatments. This work highlights the potential for protein-based approaches in tackling acne effectively.
Our analysis revealed 19 proteins significantly linked to acne risk. Among these, two proteins stood out—FSTL1 and ANXA5. We found that higher levels of these proteins were associated with an increased likelihood of developing acne, with each one-standard deviation rise corresponding to a 24% and 32% increase in acne incidence, respectively.
Using advanced genetic analysis methods, we confirmed these findings and suggested that these proteins could be valuable targets for new acne treatments. This work highlights the potential for protein-based approaches in tackling acne effectively.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Heals acne scars
GREAT FOR HAIR AND SKIN. I absolutely adore these! I take several daily, and it has significantly improved my very damaged hair while also helping to reduce the acne scarring on my face.
