Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.6
USERS' SCORE
Moderately Good
Based on 10 Reviews
7.9
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Selenium (elemental)(from 40 mg L-Selenomethionine)
200 mcg
364%
Top Medical Research Studies
9.5
We explored the effects of ebselen, a selenium compound known for its antioxidant properties, on blood clot formation in rats. Our study demonstrated that ebselen significantly delayed thrombus formation in microvessels.
In particular, animals treated with ebselen showed a marked delay in vessel occlusion compared to those treated with a control substance. In most cases, ebselen entirely prevented blood clot formation in arterioles.
This suggests that ebselen can be effective in reducing the risk of blood clots, particularly in situations characterized by oxidative stress.
In particular, animals treated with ebselen showed a marked delay in vessel occlusion compared to those treated with a control substance. In most cases, ebselen entirely prevented blood clot formation in arterioles.
This suggests that ebselen can be effective in reducing the risk of blood clots, particularly in situations characterized by oxidative stress.
Read More
7
We explored how low-dose antioxidant supplements affect urinary markers linked to blood clotting and cardiovascular health. In this randomized, double-blind, placebo-controlled study with 186 healthy volunteers, one group received supplements while the other received a placebo for two years.
Our findings show that participants who took the multi-antioxidants had significantly lower levels of a specific urinary marker associated with platelet activity. Notably, selenium was particularly linked to these results, suggesting it can help reduce clot formation, which might support heart health.
Our findings show that participants who took the multi-antioxidants had significantly lower levels of a specific urinary marker associated with platelet activity. Notably, selenium was particularly linked to these results, suggesting it can help reduce clot formation, which might support heart health.
Read More
7
Our study explored how selenium influences the interaction between platelets and endothelial cells, especially regarding blood clot formation. We noticed that selenium supplementation increased the activity of protective enzymes in both platelets and endothelial cells.
Interestingly, we found that platelets showed reduced aggregation in the presence of selenium-rich endothelial cells. However, this effect was nullified when we used aspirin, indicating a complex relationship. Ultimately, while selenium shows promise, we did not find significant improvements in nitric oxide levels linked to clot prevention.
Interestingly, we found that platelets showed reduced aggregation in the presence of selenium-rich endothelial cells. However, this effect was nullified when we used aspirin, indicating a complex relationship. Ultimately, while selenium shows promise, we did not find significant improvements in nitric oxide levels linked to clot prevention.
Read More
Most Useful Reviews
9
Essential for wellness
I prefer natural vitamins, but I make an exception for selenium due to its undeniable benefits. Within days, I noticed its antioxidant effects, which are crucial for cardiovascular health. Selenium is vital for the formation and function of red blood cells, and it supports overall immunity. It's remarkable how selenium fulfills numerous biological roles, protecting my body from harmful radicals and bolstering nutrient absorption. It's a necessary addition to my health regimen.
Read More
9
Combats deficiency issues
Selenium is vital for thyroid hormone functionality and a staggering 80% of people suffer from its deficiency, leading to various health issues. Personally, I struggled with lethargy, high blood pressure, and weight gain due to hypothyroidism. After taking selenium combined with natural iodine and L-tyrosine for six months, my metabolism normalised, energy levels surged, and I lost significant weight. This experience has convinced me of selenium's importance in combating health problems associated with deficiencies.
Read More
9
Good quality product
Excellent! Blood tests indicated that the product is of good quality and effectively raised my levels.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.6
- All Researches
9.5
We explored a new approach to treat blood clots using piezoelectric selenene. This study introduced a unique design that combines selenene with platelet membranes, enhancing its ability to target thrombosis.
Under ultrasound, the selenene generates reactive oxygen species, effectively dissolving clots without the bleeding risks associated with traditional therapies.
In both lab and live animal tests, these selenium-based nanosheets demonstrated impressive results, outperforming a standard clinical drug. It's a promising step toward safer, more effective treatments for thrombosis.
Under ultrasound, the selenene generates reactive oxygen species, effectively dissolving clots without the bleeding risks associated with traditional therapies.
In both lab and live animal tests, these selenium-based nanosheets demonstrated impressive results, outperforming a standard clinical drug. It's a promising step toward safer, more effective treatments for thrombosis.
Read More
9.5
We explored the effects of ebselen, a selenium compound known for its antioxidant properties, on blood clot formation in rats. Our study demonstrated that ebselen significantly delayed thrombus formation in microvessels.
In particular, animals treated with ebselen showed a marked delay in vessel occlusion compared to those treated with a control substance. In most cases, ebselen entirely prevented blood clot formation in arterioles.
This suggests that ebselen can be effective in reducing the risk of blood clots, particularly in situations characterized by oxidative stress.
In particular, animals treated with ebselen showed a marked delay in vessel occlusion compared to those treated with a control substance. In most cases, ebselen entirely prevented blood clot formation in arterioles.
This suggests that ebselen can be effective in reducing the risk of blood clots, particularly in situations characterized by oxidative stress.
Read More
9
We explored the effectiveness of a new polymer infused with selenium in tackling blood clots and infections associated with medical devices. This SNAP-Se-1 composite works by releasing nitric oxide (NO), a natural defender against both issues. We found that it remarkably reduced platelet adhesion by 85.5% while also displaying antibacterial properties. Importantly, this innovative approach minimizes the need for traditional antibiotic treatments. Overall, while we see promising results in lab settings, further research is needed to confirm these benefits in real-world applications.
Read More
8
We investigated how selenium-based nanomaterials boost photoacoustic imaging to identify carotid artery blood clots more effectively. By using a thrombosis model in mice, we found that these nanocomposites significantly enhanced imaging signals—up to 5 times greater—which helps diagnose the extent of carotid atherosclerosis.
This research suggests that selenium/polypyrrole nanoparticles may be a promising tool for improving the detection and diagnosis of carotid thrombosis, potentially leading to better stroke prevention strategies.
This research suggests that selenium/polypyrrole nanoparticles may be a promising tool for improving the detection and diagnosis of carotid thrombosis, potentially leading to better stroke prevention strategies.
Read More
7
We explored how low-dose antioxidant supplements affect urinary markers linked to blood clotting and cardiovascular health. In this randomized, double-blind, placebo-controlled study with 186 healthy volunteers, one group received supplements while the other received a placebo for two years.
Our findings show that participants who took the multi-antioxidants had significantly lower levels of a specific urinary marker associated with platelet activity. Notably, selenium was particularly linked to these results, suggesting it can help reduce clot formation, which might support heart health.
Our findings show that participants who took the multi-antioxidants had significantly lower levels of a specific urinary marker associated with platelet activity. Notably, selenium was particularly linked to these results, suggesting it can help reduce clot formation, which might support heart health.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 10 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
Essential for wellness
I prefer natural vitamins, but I make an exception for selenium due to its undeniable benefits. Within days, I noticed its antioxidant effects, which are crucial for cardiovascular health. Selenium is vital for the formation and function of red blood cells, and it supports overall immunity. It's remarkable how selenium fulfills numerous biological roles, protecting my body from harmful radicals and bolstering nutrient absorption. It's a necessary addition to my health regimen.
Read More
9
Combats deficiency issues
Selenium is vital for thyroid hormone functionality and a staggering 80% of people suffer from its deficiency, leading to various health issues. Personally, I struggled with lethargy, high blood pressure, and weight gain due to hypothyroidism. After taking selenium combined with natural iodine and L-tyrosine for six months, my metabolism normalised, energy levels surged, and I lost significant weight. This experience has convinced me of selenium's importance in combating health problems associated with deficiencies.
Read More
9
Good quality product
Excellent! Blood tests indicated that the product is of good quality and effectively raised my levels.
Read More
7.5
Enhanced iodine effect
65 people found this helpful
Selenium was the missing link for my iodine supplements. After two weeks of daily doses of chelated selenium, my overall well-being significantly improved and fatigue diminished. This was a turning point as iodine finally began to work in my body. After seven months, tests for trace elements showed ideal values for both selenium and iodine, with reduced heavy metals. Selenium activated iodine’s effects and enhanced vitamin E's properties, also contributing to the production of glutathione. I learned that selenium's persistent deficiency can be linked to various health issues, and taking it with iodine, vitamin E, and L-Tyrosine provided an even greater positive effect.
Read More
6
Strengthened immunity
8 people found this helpful
I've been taking selenium for my autoimmune thyroiditis as prescribed by my doctor, and the results have been fantastic! My immunity feels notably strengthened, and I received my order promptly. Selenium is crucial for converting T4 to T3, and its antioxidant action protects cells from free radicals. It supports white blood cells and contributes to a healthier heart by regulating cholesterol levels. This product reassures me, as I trust in the quality of NOW products. It feels empowering to take one capsule a day, preparing me for whatever health battles lie ahead!
Read More
Frequently Asked Questions
9
Essential for wellness
I prefer natural vitamins, but I make an exception for selenium due to its undeniable benefits. Within days, I noticed its antioxidant effects, which are crucial for cardiovascular health. Selenium is vital for the formation and function of red blood cells, and it supports overall immunity. It's remarkable how selenium fulfills numerous biological roles, protecting my body from harmful radicals and bolstering nutrient absorption. It's a necessary addition to my health regimen.
7.5
Enhanced iodine effect
65 people found this helpful
Selenium was the missing link for my iodine supplements. After two weeks of daily doses of chelated selenium, my overall well-being significantly improved and fatigue diminished. This was a turning point as iodine finally began to work in my body. After seven months, tests for trace elements showed ideal values for both selenium and iodine, with reduced heavy metals. Selenium activated iodine’s effects and enhanced vitamin E's properties, also contributing to the production of glutathione. I learned that selenium's persistent deficiency can be linked to various health issues, and taking it with iodine, vitamin E, and L-Tyrosine provided an even greater positive effect.
9
Combats deficiency issues
Selenium is vital for thyroid hormone functionality and a staggering 80% of people suffer from its deficiency, leading to various health issues. Personally, I struggled with lethargy, high blood pressure, and weight gain due to hypothyroidism. After taking selenium combined with natural iodine and L-tyrosine for six months, my metabolism normalised, energy levels surged, and I lost significant weight. This experience has convinced me of selenium's importance in combating health problems associated with deficiencies.
6
Strengthened immunity
8 people found this helpful
I've been taking selenium for my autoimmune thyroiditis as prescribed by my doctor, and the results have been fantastic! My immunity feels notably strengthened, and I received my order promptly. Selenium is crucial for converting T4 to T3, and its antioxidant action protects cells from free radicals. It supports white blood cells and contributes to a healthier heart by regulating cholesterol levels. This product reassures me, as I trust in the quality of NOW products. It feels empowering to take one capsule a day, preparing me for whatever health battles lie ahead!
7.5
Prevents blood clots
1 people found this helpful
I started taking selenium for its antioxidant properties and its role in preventing blood clots. As an essential amino acid, its benefits became clear right away. I've noticed significant improvements in my overall health since I began this supplement, and I plan to continue taking it long-term. It's vital to my health regimen, and I appreciate its role in detoxification as well. I wholeheartedly recommend selenium for anyone seeking to enhance their health.
0
Caution advised
Caution, it acts as a significant blood thinner! After three weeks, I experienced haemorrhages in my eye; I consulted an ophthalmologist to address this issue.
6
Supports blood flow
I've found selenium to be an outstanding antioxidant. It notably supports healthy blood flow and is beneficial for individuals with asthma. Protecting against oxidative stress, I feel more confident in my health choices after introducing selenium into my routine. It appears to enhance overall vitality and ability to cope with daily challenges, and I'm keen to see how it further benefits my health in the long run. Definitely a supplement I'd recommend to others.
7.5
Effective selenium supplement
The therapeutic dose of chelated selenium is perfectly effective in raising its level in the blood; a single can for two courses is just sufficient.
9.5
We explored the effects of ebselen, a selenium compound known for its antioxidant properties, on blood clot formation in rats. Our study demonstrated that ebselen significantly delayed thrombus formation in microvessels.
In particular, animals treated with ebselen showed a marked delay in vessel occlusion compared to those treated with a control substance. In most cases, ebselen entirely prevented blood clot formation in arterioles.
This suggests that ebselen can be effective in reducing the risk of blood clots, particularly in situations characterized by oxidative stress.
In particular, animals treated with ebselen showed a marked delay in vessel occlusion compared to those treated with a control substance. In most cases, ebselen entirely prevented blood clot formation in arterioles.
This suggests that ebselen can be effective in reducing the risk of blood clots, particularly in situations characterized by oxidative stress.
7
We explored the role of selenium in blood clotting, particularly its impact on platelets in people who are selenium-deficient. This research highlights how selenium helps manage the activity of glutathione peroxidase, an important enzyme in the body.
When selenium levels are low, platelets tend to become overly active, leading to increased clotting risks. However, we observed that selenium supplementation can enhance the activity of this enzyme, reducing platelet aggregation and potentially lowering the chances of thrombosis and heart disease.
About 10% of the population in France is selenium-deficient, so increasing selenium intake may provide health benefits in preventing vascular issues for these individuals.
When selenium levels are low, platelets tend to become overly active, leading to increased clotting risks. However, we observed that selenium supplementation can enhance the activity of this enzyme, reducing platelet aggregation and potentially lowering the chances of thrombosis and heart disease.
About 10% of the population in France is selenium-deficient, so increasing selenium intake may provide health benefits in preventing vascular issues for these individuals.
9
We explored the effectiveness of a new polymer infused with selenium in tackling blood clots and infections associated with medical devices. This SNAP-Se-1 composite works by releasing nitric oxide (NO), a natural defender against both issues. We found that it remarkably reduced platelet adhesion by 85.5% while also displaying antibacterial properties. Importantly, this innovative approach minimizes the need for traditional antibiotic treatments. Overall, while we see promising results in lab settings, further research is needed to confirm these benefits in real-world applications.
8
We investigated how selenium-based nanomaterials boost photoacoustic imaging to identify carotid artery blood clots more effectively. By using a thrombosis model in mice, we found that these nanocomposites significantly enhanced imaging signals—up to 5 times greater—which helps diagnose the extent of carotid atherosclerosis.
This research suggests that selenium/polypyrrole nanoparticles may be a promising tool for improving the detection and diagnosis of carotid thrombosis, potentially leading to better stroke prevention strategies.
This research suggests that selenium/polypyrrole nanoparticles may be a promising tool for improving the detection and diagnosis of carotid thrombosis, potentially leading to better stroke prevention strategies.
References
- Hu H, Xia L, Wang J, Huang X, Zhao Q, et al. Bionanoengineered 2D monoelemental selenene for piezothrombolysis. Biomaterials. 2024;305:122468. 10.1016/j.biomaterials.2024.122468
- He F, Hou W, Lan Y, Gao W, Zhou M, et al. High Contrast Detection of Carotid Neothrombus with Strong Near-Infrared Absorption Selenium Nanosphere Enhanced Photoacoustic Imaging. Int J Nanomedicine. 2023;18:4043. 10.2147/IJN.S404743
- Mondal A, Douglass M, Hopkins SP, Singha P, Tran M, et al. Multifunctional Nitroso--acetylpenicillamine-Incorporated Medical-Grade Polymer with Selenium Interface for Biomedical Applications. ACS Appl Mater Interfaces. 2019;11:34652. 10.1021/acsami.9b10610
- Arnaud J, Bost M, Vitoux D, Labarère J, Galan P, et al. Effect of low dose antioxidant vitamin and trace element supplementation on the urinary concentrations of thromboxane and prostacyclin metabolites. J Am Coll Nutr. 2007;26:405.
- Lindenblatt N, Schareck W, Belusa L, Nickels RM, Menger MD, et al. Anti-oxidant ebselen delays microvascular thrombus formation in the rat cremaster muscle by inhibiting platelet P-selectin expression. Thromb Haemost. 2003;90:882.
- Ricetti MM, Guidi GC, Tecchio C, Bellisola G, Rigo A, et al. Effects of sodium selenite on in vitro interactions between platelets and endothelial cells. Int J Clin Lab Res. 1999;29:80.
- Vitoux D, Chappuis P, Arnaud J, Bost M, Accominotti M, et al. [Selenium, glutathione peroxidase, peroxides and platelet functions]. Ann Biol Clin (Paris). 1996;54:181.
- Herrick AL, Rieley F, Schofield D, Hollis S, Braganza JM, et al. Micronutrient antioxidant status in patients with primary Raynaud's phenomenon and systemic sclerosis. J Rheumatol. 1994;21:1477.
- Perona G, Schiavon R, Guidi GC, Veneri D, Minuz P. Selenium dependent glutathione peroxidase: a physiological regulatory system for platelet function. Thromb Haemost. 1990;64:312.
