Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 8 Reviews
8.5
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Selenium (elemental)(from 40 mg L-Selenomethionine)
200 mcg
364%
Top Medical Research Studies
8
We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
8
We explored how sweet corn cob polysaccharide selenium nanoparticles (U-SCPSeNPs) might help alleviate symptoms of chronic fatigue syndrome (CFS). In this study, we used mouse models to test the effects of these nanoparticles, which were created using an ultrasound-assisted method.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
7
CoQ10 and selenium may benefit ME/CFS
We explored whether combining Coenzyme Q10 and selenium could improve outcomes for individuals with chronic fatigue syndrome (ME/CFS). In this study, 27 patients took an oral supplement for 8 weeks. While we noted improvements in overall fatigue severity and quality of life, sleep disturbances did not show any significant change. Additionally, we found increased antioxidant capacity and decreased inflammatory markers, indicating potential benefits. However, other key biomarkers did not show significant changes. Overall, this suggests that long-term supplementation might help some symptoms in ME/CFS.
Most Useful Reviews
9
Elevated mood
111 people found this helpful
The product arrived promptly, and the capsules are easy to take. After a month of use, I feel energetic, especially during this typically fatigue-heavy autumn. With Selenium, I am enjoying elevated spirits and less hair loss, which is exceptional for this time of year. I highly recommend it!
9
Fatigue alleviated
5 people found this helpful
The goods arrived on time. Well packed and undamaged. The small Lego-like capsules are easy to swallow with no aftertaste. I have felt good for a month now. Typically in autumn, fatigue and lethargy set in, but with "Selenium", everything is different—no fatigue and my mood is uplifted. My hair falls out less too! Highly recommend.
9
Improved well-being
I received the vitamins and am satisfied with the quality; the packaging is good, and the composition matches the description. After one month of use, I noticed considerable effects: increased energy, reduced fatigue, and improved general well-being. I plan to order more.
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
- All Researches
8
We explored how sweet corn cob polysaccharide selenium nanoparticles (U-SCPSeNPs) might help alleviate symptoms of chronic fatigue syndrome (CFS). In this study, we used mouse models to test the effects of these nanoparticles, which were created using an ultrasound-assisted method.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
8
We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
7
CoQ10 and selenium may benefit ME/CFS
We explored whether combining Coenzyme Q10 and selenium could improve outcomes for individuals with chronic fatigue syndrome (ME/CFS). In this study, 27 patients took an oral supplement for 8 weeks. While we noted improvements in overall fatigue severity and quality of life, sleep disturbances did not show any significant change. Additionally, we found increased antioxidant capacity and decreased inflammatory markers, indicating potential benefits. However, other key biomarkers did not show significant changes. Overall, this suggests that long-term supplementation might help some symptoms in ME/CFS.
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Elevated mood
111 people found this helpful
The product arrived promptly, and the capsules are easy to take. After a month of use, I feel energetic, especially during this typically fatigue-heavy autumn. With Selenium, I am enjoying elevated spirits and less hair loss, which is exceptional for this time of year. I highly recommend it!
9
Fatigue alleviated
5 people found this helpful
The goods arrived on time. Well packed and undamaged. The small Lego-like capsules are easy to swallow with no aftertaste. I have felt good for a month now. Typically in autumn, fatigue and lethargy set in, but with "Selenium", everything is different—no fatigue and my mood is uplifted. My hair falls out less too! Highly recommend.
9
Improved well-being
I received the vitamins and am satisfied with the quality; the packaging is good, and the composition matches the description. After one month of use, I noticed considerable effects: increased energy, reduced fatigue, and improved general well-being. I plan to order more.
7.5
Immune support noted
9 people found this helpful
Great immunostimulator!!! Hello everyone. I'm from Ukraine!!!! 
Autumn and winter are approaching, so we decided to purchase this natural antioxidant to stimulate the immune system, as I frequently experience fatigue and weakness. Thank you iHerb for the wonderful composition of 200 μg. Peace and health to all!!!
Autumn and winter are approaching, so we decided to purchase this natural antioxidant to stimulate the immune system, as I frequently experience fatigue and weakness. Thank you iHerb for the wonderful composition of 200 μg. Peace and health to all!!!7.5
Increased energy
4 people found this helpful
Selenium ordered myself due to a deficiency symptom. My hair began to fall out noticeably, and I felt worse. My attentive doctor recommended that I take selenium, an essential trace element for health. I've been taking one capsule daily for over a month. From this dietary supplement, I noticed increased energy, and my morning fatigue has vanished. The condition of my skin and nails has improved, and my hair has stopped falling out. Excellent selenium; it's very beneficial.
Frequently Asked Questions
9
Elevated mood
111 people found this helpful
The product arrived promptly, and the capsules are easy to take. After a month of use, I feel energetic, especially during this typically fatigue-heavy autumn. With Selenium, I am enjoying elevated spirits and less hair loss, which is exceptional for this time of year. I highly recommend it!
9
Improved well-being
I received the vitamins and am satisfied with the quality; the packaging is good, and the composition matches the description. After one month of use, I noticed considerable effects: increased energy, reduced fatigue, and improved general well-being. I plan to order more.
7.5
Increased energy
4 people found this helpful
Selenium ordered myself due to a deficiency symptom. My hair began to fall out noticeably, and I felt worse. My attentive doctor recommended that I take selenium, an essential trace element for health. I've been taking one capsule daily for over a month. From this dietary supplement, I noticed increased energy, and my morning fatigue has vanished. The condition of my skin and nails has improved, and my hair has stopped falling out. Excellent selenium; it's very beneficial.
9
Fatigue alleviated
5 people found this helpful
The goods arrived on time. Well packed and undamaged. The small Lego-like capsules are easy to swallow with no aftertaste. I have felt good for a month now. Typically in autumn, fatigue and lethargy set in, but with "Selenium", everything is different—no fatigue and my mood is uplifted. My hair falls out less too! Highly recommend.
6
Combats fatigue
1 people found this helpful
In addition to enhancing the immune system, it also combats mental exhaustion and fatigue! I consume it frequently!
7.5
Immune support noted
9 people found this helpful
Great immunostimulator!!! Hello everyone. I'm from Ukraine!!!! Autumn and winter are approaching, so we decided to purchase this natural antioxidant to stimulate the immune system, as I frequently experience fatigue and weakness. Thank you iHerb for the wonderful composition of 200 μg. Peace and health to all!!!
Autumn and winter are approaching, so we decided to purchase this natural antioxidant to stimulate the immune system, as I frequently experience fatigue and weakness. Thank you iHerb for the wonderful composition of 200 μg. Peace and health to all!!!7.5
Energy boost
I took inferior selenium for three months. I noticed improvements in my thyroid function, though my tests didn’t confirm it. I experienced reduced fatigue and increased energy. There were no side effects, and I recommend it!
8
We explored how sweet corn cob polysaccharide selenium nanoparticles (U-SCPSeNPs) might help alleviate symptoms of chronic fatigue syndrome (CFS). In this study, we used mouse models to test the effects of these nanoparticles, which were created using an ultrasound-assisted method.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
7
CoQ10 and selenium may benefit ME/CFS
We explored whether combining Coenzyme Q10 and selenium could improve outcomes for individuals with chronic fatigue syndrome (ME/CFS). In this study, 27 patients took an oral supplement for 8 weeks. While we noted improvements in overall fatigue severity and quality of life, sleep disturbances did not show any significant change. Additionally, we found increased antioxidant capacity and decreased inflammatory markers, indicating potential benefits. However, other key biomarkers did not show significant changes. Overall, this suggests that long-term supplementation might help some symptoms in ME/CFS.
8
We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
References
- Wang J, Wang X, Xiu W, Li C, Yu S, et al. Ultrasound-assisted preparation of sweet corn cob polysaccharide selenium nanoparticles alleviates symptoms of chronic fatigue syndrome. Food Funct. 2025;16:133. doi:10.1039/d4fo04195j
- Castro-Marrero J, Domingo JC, Cordobilla B, Ferrer R, Giralt M, et al. Does Coenzyme Q10 Plus Selenium Supplementation Ameliorate Clinical Outcomes by Modulating Oxidative Stress and Inflammation in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?. Antioxid Redox Signal. 2022;36:729. doi:10.1089/ars.2022.0018
- Shao C, Song J, Zhao S, Jiang H, Wang B, et al. Therapeutic Effect and Metabolic Mechanism of A Selenium-Polysaccharide from Green Tea on Chronic Fatigue Syndrome. Polymers (Basel). 2018;10. doi:10.3390/polym10111269
