Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.9
USERS' SCORE
Good
Based on 6 Reviews
8.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Selenium (elemental)(from 40 mg L-Selenomethionine)
200 mcg
364%
Top Medical Research Studies
9.5
Selenium nanoparticles reduce liver toxicity
We investigated how selenium nanoparticles (Se-NPs) and chitosan-encapsulated selenium nanoparticles (Se-CS-NPs) can mitigate liver toxicity induced by carbon tetrachloride (CCl) in rats. In our study, eighty rats were divided into eight groups, including placebo and control.
The findings indicated that both forms of selenium helped in reducing liver damage by influencing key biological markers. Notably, while selenium was effective, encapsulating it with chitosan did not provide additional benefits. Overall, these nanoparticles could be a valuable treatment option against liver toxicity.
The findings indicated that both forms of selenium helped in reducing liver damage by influencing key biological markers. Notably, while selenium was effective, encapsulating it with chitosan did not provide additional benefits. Overall, these nanoparticles could be a valuable treatment option against liver toxicity.
8
We examined how selenium nanoparticles might help combat liver damage caused by cadmium, a dangerous environmental toxin. By studying both animal models and liver cells, we found that these nanoparticles could reduce cell injuries linked to a damaging process called ferroptosis.
Our findings indicated that achieving this protective effect involves enhancing certain liver enzyme activities and altering several protein levels associated with oxidative stress. Overall, while selenium shows promise in mitigating liver damage, particularly against cadmium toxicity, further research could better clarify its mechanisms and potential benefits.
Our findings indicated that achieving this protective effect involves enhancing certain liver enzyme activities and altering several protein levels associated with oxidative stress. Overall, while selenium shows promise in mitigating liver damage, particularly against cadmium toxicity, further research could better clarify its mechanisms and potential benefits.
9
We explored the potential of selenium in addressing liver damage caused by alcohol. The study employed both in vitro and in vivo methods to assess how selenium affects liver cells exposed to ethanol.
Our findings indicated that selenium improved cell viability, reduced oxidative stress markers, and altered certain protein expressions related to cell death. In particular, selenomethionine showed a notable impact in protecting liver cells.
Overall, selenium appears promising for alleviating ethanol-induced liver injury by regulating important cellular processes. However, results suggest that further research is needed to fully understand its effectiveness.
Our findings indicated that selenium improved cell viability, reduced oxidative stress markers, and altered certain protein expressions related to cell death. In particular, selenomethionine showed a notable impact in protecting liver cells.
Overall, selenium appears promising for alleviating ethanol-induced liver injury by regulating important cellular processes. However, results suggest that further research is needed to fully understand its effectiveness.
Most Useful Reviews
9
Cleanses the body
The ingredients and quantity are adequate, suitable for all ages. This product has wonderful benefits, facilitating radical cleansing in the body. The formula acts as a strong oxidizer for the liver. The taste is neutral and I plan to reorder due to its effectiveness.
7.5
Numerous benefits
52 people found this helpful
Following Dr Berg's advice, I take selenium daily for its many benefits. It aids with indigestion, heart health, diabetes complications, and is crucial for liver enzyme production. It also helps with mercury removal. I feel strong and active with regular use.
7.5
Liver enzyme support
34 people found this helpful
Selenium offers various benefits, notably as an antioxidant and for enhancing liver enzyme production. I take it daily after meals to help expel toxins. Prolonged use leads to increased energy and well-being.
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.9
- All Researches
9.5
Selenium nanoparticles reduce liver toxicity
We investigated how selenium nanoparticles (Se-NPs) and chitosan-encapsulated selenium nanoparticles (Se-CS-NPs) can mitigate liver toxicity induced by carbon tetrachloride (CCl) in rats. In our study, eighty rats were divided into eight groups, including placebo and control.
The findings indicated that both forms of selenium helped in reducing liver damage by influencing key biological markers. Notably, while selenium was effective, encapsulating it with chitosan did not provide additional benefits. Overall, these nanoparticles could be a valuable treatment option against liver toxicity.
The findings indicated that both forms of selenium helped in reducing liver damage by influencing key biological markers. Notably, while selenium was effective, encapsulating it with chitosan did not provide additional benefits. Overall, these nanoparticles could be a valuable treatment option against liver toxicity.
9
We aimed to investigate the role of selenium and coenzyme Q in addressing liver damage caused by a methionine choline-deficient diet in mice. Over four weeks, mice receiving the combination treatment showed significant reductions in liver inflammation, fibrosis, and oxidative stress.
The results suggested that this combined supplementation might hold therapeutic potential against metabolic dysfunction-associated liver injury. While our findings are promising, they are based on an animal model, and further research is necessary to explore their implications for human liver disease.
The results suggested that this combined supplementation might hold therapeutic potential against metabolic dysfunction-associated liver injury. While our findings are promising, they are based on an animal model, and further research is necessary to explore their implications for human liver disease.
9
Selenium enhances liver health
We set out to investigate if selenium, along with glutathione, can help reduce liver injury caused by a cancer-inducing substance in mice. Over 20 weeks, we divided male mice into different groups, some receiving selenium and others just glutathione, while monitoring their liver function.
Our findings revealed that both supplements significantly improved liver conditions and antioxidant levels. Interestingly, adding selenium to glutathione treatment worked even better, enhancing the liver’s ability to handle oxidative stress. Overall, selenium appears to be a promising ally in supporting liver health and reducing injury.
Our findings revealed that both supplements significantly improved liver conditions and antioxidant levels. Interestingly, adding selenium to glutathione treatment worked even better, enhancing the liver’s ability to handle oxidative stress. Overall, selenium appears to be a promising ally in supporting liver health and reducing injury.
9
We explored the potential of selenium in addressing liver damage caused by alcohol. The study employed both in vitro and in vivo methods to assess how selenium affects liver cells exposed to ethanol.
Our findings indicated that selenium improved cell viability, reduced oxidative stress markers, and altered certain protein expressions related to cell death. In particular, selenomethionine showed a notable impact in protecting liver cells.
Overall, selenium appears promising for alleviating ethanol-induced liver injury by regulating important cellular processes. However, results suggest that further research is needed to fully understand its effectiveness.
Our findings indicated that selenium improved cell viability, reduced oxidative stress markers, and altered certain protein expressions related to cell death. In particular, selenomethionine showed a notable impact in protecting liver cells.
Overall, selenium appears promising for alleviating ethanol-induced liver injury by regulating important cellular processes. However, results suggest that further research is needed to fully understand its effectiveness.
8
We investigated whether selenium-modified Bletilla striata polysaccharide (Se-BSP) could effectively reduce liver fibrosis. Our findings revealed that Se-BSP not only improved its antioxidant properties but also showed greater efficacy in alleviating liver fibrosis compared to its unmodified version at a specific concentration. This study underscores the potential of Se-BSP as a promising treatment for liver fibrosis, a condition that can lead to more severe liver diseases.
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Cleanses the body
The ingredients and quantity are adequate, suitable for all ages. This product has wonderful benefits, facilitating radical cleansing in the body. The formula acts as a strong oxidizer for the liver. The taste is neutral and I plan to reorder due to its effectiveness.
7.5
Numerous benefits
52 people found this helpful
Following Dr Berg's advice, I take selenium daily for its many benefits. It aids with indigestion, heart health, diabetes complications, and is crucial for liver enzyme production. It also helps with mercury removal. I feel strong and active with regular use.
7.5
Liver enzyme support
34 people found this helpful
Selenium offers various benefits, notably as an antioxidant and for enhancing liver enzyme production. I take it daily after meals to help expel toxins. Prolonged use leads to increased energy and well-being.
7.5
Supports liver health
1 people found this helpful
Due to my late nights, I read that selenium is beneficial for the liver and thyroid. This product suits my needs perfectly, and I'm hopeful for improvements in my condition.
7.5
Detoxifies the liver
3 people found this helpful
The package contains selenium mineral at 200 micrograms per pill, using a fast-absorbing selenomethionine formula. I take one capsule each evening, which is vegetarian, halal, soy-free, and gluten-free. With 90 pills sufficient for three months, this concentration is particularly good for regulating thyroid hormones and detoxifying the liver. I also follow strict dietary guidelines to maximise benefits.
Frequently Asked Questions
7.5
Numerous benefits
52 people found this helpful
Following Dr Berg's advice, I take selenium daily for its many benefits. It aids with indigestion, heart health, diabetes complications, and is crucial for liver enzyme production. It also helps with mercury removal. I feel strong and active with regular use.
7.5
Liver enzyme support
34 people found this helpful
Selenium offers various benefits, notably as an antioxidant and for enhancing liver enzyme production. I take it daily after meals to help expel toxins. Prolonged use leads to increased energy and well-being.
7.5
Strengthens immunity
1 people found this helpful
This product is excellent for liver health when used with silymarin and alpha-lipoic acid. I've noticed a significant improvement in my ability to avoid illness around others.
9
Cleanses the body
The ingredients and quantity are adequate, suitable for all ages. This product has wonderful benefits, facilitating radical cleansing in the body. The formula acts as a strong oxidizer for the liver. The taste is neutral and I plan to reorder due to its effectiveness.
7.5
Supports liver health
1 people found this helpful
Due to my late nights, I read that selenium is beneficial for the liver and thyroid. This product suits my needs perfectly, and I'm hopeful for improvements in my condition.
7.5
Detoxifies the liver
3 people found this helpful
The package contains selenium mineral at 200 micrograms per pill, using a fast-absorbing selenomethionine formula. I take one capsule each evening, which is vegetarian, halal, soy-free, and gluten-free. With 90 pills sufficient for three months, this concentration is particularly good for regulating thyroid hormones and detoxifying the liver. I also follow strict dietary guidelines to maximise benefits.
8
We investigated whether selenium-modified Bletilla striata polysaccharide (Se-BSP) could effectively reduce liver fibrosis. Our findings revealed that Se-BSP not only improved its antioxidant properties but also showed greater efficacy in alleviating liver fibrosis compared to its unmodified version at a specific concentration. This study underscores the potential of Se-BSP as a promising treatment for liver fibrosis, a condition that can lead to more severe liver diseases.
9
We aimed to investigate the role of selenium and coenzyme Q in addressing liver damage caused by a methionine choline-deficient diet in mice. Over four weeks, mice receiving the combination treatment showed significant reductions in liver inflammation, fibrosis, and oxidative stress.
The results suggested that this combined supplementation might hold therapeutic potential against metabolic dysfunction-associated liver injury. While our findings are promising, they are based on an animal model, and further research is necessary to explore their implications for human liver disease.
The results suggested that this combined supplementation might hold therapeutic potential against metabolic dysfunction-associated liver injury. While our findings are promising, they are based on an animal model, and further research is necessary to explore their implications for human liver disease.
7
We investigated the connection between selenium levels in the blood and non-alcoholic fatty liver disease (NAFLD), a common liver issue. Analyzing data from over 7,000 participants in the NHANES survey, we found that higher selenium levels were linked to an increased prevalence of NAFLD in both genders. Interestingly, those with higher selenium levels also showed a decreased prevalence of advanced hepatic fibrosis. This suggests that while selenium might be associated with NAFLD, it may also provide some protective benefits against severe liver damage.
References
- Jiang G, Kong H, Wang Y, Wang Y, Zhou J, et al. Antioxidant and hepatic fibrosis-alleviating effects of selenium-modified Bletilla striata polysaccharide. Int J Biol Macromol. 2025;301:140234. doi:10.1016/j.ijbiomac.2025.140234
- Choi H, Choi J, Go Y, Chung J. Coenzyme Q and Selenium Co-Supplementation Alleviate Methionine Choline-Deficient Diet-Induced Metabolic Dysfunction-Associated Steatohepatitis in Mice. Nutrients. 2025;17. doi:10.3390/nu17020229
- Guo W, Weng T, Song Y. Association of serum selenium with MASLD and liver fibrosis: A cross-sectional study. PLoS One. 2024;19:e0314780. doi:10.1371/journal.pone.0314780
- Yang Z, Lian J, Li J, Guo W, Ni L, et al. Intestinal Microbiomics and Liver Metabolomics Insights into the Ameliorative Effects of Selenium-Enriched FZU3103 on Alcohol-Induced Liver Injury in Mice. J Agric Food Chem. 2025;73:3232. doi:10.1021/acs.jafc.4c06072
- Shen Q, Liu Y, Li J, Zhou D. Nano-Selenium Modulates NF-κB/NLRP3 Pathway and Mitochondrial Dynamics to Attenuate Microplastic-Induced Liver Injury. Nutrients. 2024;16. doi:10.3390/nu16223878
- Liu Q, Bi J, Fan G, Wu M, Qin X, et al. Association between multiple metals exposure and metabolic dysfunction-associated fatty liver disease among Chinese adults. J Trace Elem Med Biol. 2024;86:127566. doi:10.1016/j.jtemb.2024.127566
- Chen X, Lin X. Sodium selenite antagonizes trimethyl tin-induced chicken hepatotoxic hepatitis through the RNS/NF-κB/NLRP3 pathway. Poult Sci. 2025;104:104449. doi:10.1016/j.psj.2024.104449
- Mrwad AA, El-Shafey SE, Said NM. Chitosan-encapsulated selenium nanoparticles alleviate CCl induced hepatotoxicity through synergistically modulating NF-κB and Nrf2 signaling pathways and regulating Bcl-2 and Caspase-3 expression: A comprehensive study with multiple regression analysis. J Trace Elem Med Biol. 2024;86:127563. doi:10.1016/j.jtemb.2024.127563
- Hsiao YF, Huang SC, Cheng SB, Hsu CC, Huang YC. Glutathione and Selenium Supplementation Attenuates Liver Injury in Diethylnitrosamine-Induced Hepatocarcinogenic Mice by Enhancing Glutathione-Related Antioxidant Capacities. Int J Mol Sci. 2024;25. doi:10.3390/ijms252111339
- Cengiz M, Gür B, Gür F, Şahintürk V, Bayrakdar A, et al. The protective effects of selenium and boron on cyclophosphamide-induced hepatic oxidative stress, inflammation, and apoptosis in rats. Heliyon. 2024;10:e38713. doi:10.1016/j.heliyon.2024.e38713
- Chen F, Li Q, Xu X, Wang F. Selenium Attenuates Ethanol-induced Hepatocellular Injury by Regulating Ferroptosis and Apoptosis. Turk J Gastroenterol. 2024;35:778. doi:10.5152/tjg.2024.24159
- Abdel-Wahhab KG, Ashry M, Hassan LK, El-Azma MH, Elqattan GM, et al. Hepatic and immune modulatory effectiveness of lactoferrin loaded Selenium nanoparticles on bleomycin induced hepatic injury. Sci Rep. 2024;14:21066. doi:10.1038/s41598-024-70894-6
- Shao C, Luo T, Wang S, Li Z, Yu X, et al. Selenium nanoparticles alleviates cadmium induced hepatotoxicity by inhibiting ferroptosis and oxidative stress in vivo and in vitro. Chemosphere. 2024;364:143004. doi:10.1016/j.chemosphere.2024.143004
- Liu Y, Wang R. Association between serum selenium and non-alcoholic fatty liver disease: Results from NHANES: An observational study. Medicine (Baltimore). 2024;103:e38845. doi:10.1097/MD.0000000000038845
- Huertas-Abril PV, Prieto-Álamo MJ, Jurado J, Pérez J, Molina-Hernández V, et al. Transcriptional and biochemical changes in mouse liver following exposure to a metal/drug cocktail. Attenuating effect of a selenium-enriched diet. Food Chem Toxicol. 2024;191:114845. doi:10.1016/j.fct.2024.114845
