Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.3
USERS' SCORE
Good
Based on 25 Reviews
8.1
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Selenium (elemental)(from 40 mg L-Selenomethionine)
200 mcg
364%
Top Medical Research Studies
9
We explored the effectiveness of a novel selenium nanocomposite, AANL-SeNPs, in treating lung cancer. This innovative compound, created from a natural ingredient, demonstrated significant inhibition of lung cancer cell growth in various cell lines, showing up to a 67% reduction in viability.
Furthermore, AANL-SeNPs slowed tumor growth in live models and appeared safe for normal cells. While promising, our findings indicate that although AANL-SeNPs upregulate the protein CLK2 and can enhance therapeutic response, further studies are needed to fully understand its potential.
Furthermore, AANL-SeNPs slowed tumor growth in live models and appeared safe for normal cells. While promising, our findings indicate that although AANL-SeNPs upregulate the protein CLK2 and can enhance therapeutic response, further studies are needed to fully understand its potential.
Read More
9
Effective selenium treatment for lung cancer
We aimed to explore the potential of selenium nanoparticles synthesized from Epimedium brevicornum in combating lung cancer. Using various techniques, we characterized these nanoparticles and evaluated their effects in both lab and live models.
Although the nanoparticles were not harmful to healthy liver cells, they effectively triggered cell death in lung cancer cells, reducing tumor growth and suppressing migration.
Our findings suggest that these selenium nanoparticles could be a promising and safe avenue for lung cancer treatment.
Although the nanoparticles were not harmful to healthy liver cells, they effectively triggered cell death in lung cancer cells, reducing tumor growth and suppressing migration.
Our findings suggest that these selenium nanoparticles could be a promising and safe avenue for lung cancer treatment.
Read More
9
Selenium nanoparticles may inhibit lung cancer
We examined how selenium nanoparticles, stabilized by Sargassum fusiforme polysaccharide, affect lung cancer cells. In lab tests, these nanoparticles were shown to inhibit the growth of A549 lung cancer cells and initiate cell apoptosis by increasing reactive oxygen species (ROS).
We also noticed that they impacted the mitochondria, altering important proteins linked to cancer cell survival. While animal studies showed a significant reduction in tumor growth without harming the animals, the potential for these nanoparticles as a viable treatment for non-small cell lung cancer seems promising.
We also noticed that they impacted the mitochondria, altering important proteins linked to cancer cell survival. While animal studies showed a significant reduction in tumor growth without harming the animals, the potential for these nanoparticles as a viable treatment for non-small cell lung cancer seems promising.
Read More
Most Useful Reviews
7.5
Cancer prevention focus
12 people found this helpful
The antioxidant properties of selenium, especially in combination with amino acids, are significant for cancer patients. I decided to purchase it after reading Professor Tokumi Fujikawa's work, highlighting selenium's role beyond vitamin C and E. Its small, easy-to-swallow veggie capsule is advantageous. The higher ingredient content compared to Japanese supplements makes it effective. Though my cancer is nearly in remission, I will continue its use to prevent recurrence.
Read More
9
Natural cancer fighter
5 people found this helpful
Awesome! Selenium is an excellent natural fighter against cancer. These small v-caps are easy to take, and I have no complaints at all.
Read More
9
Post-cancer recovery
4 people found this helpful
My husband has taken Selenium daily for years. It aids in cancer recovery; after battling prostate cancer, he remains cancer-free four years post-treatment. He supplements with vitamin C, B12, cherry for energy, D3, and vitamin E.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.3
- All Researches
9.5
We examined the role of selenium (Se) in treating advanced non-small-cell lung cancer (NSCLC). Our research revealed that a lack of selenium leads to weakened immunity and faster tumor growth in mice. Interestingly, using selenium nanoparticles showed promising results.
These nanoparticles enhanced natural killer cell activity, boosting the immune response against cancer. In a clinical trial, patients receiving selenium nanoparticles alongside standard treatments had an impressive 83.3% response rate and complete disease control.
Overall, selenium shows potential to strengthen lung cancer therapy through immune enhancement.
These nanoparticles enhanced natural killer cell activity, boosting the immune response against cancer. In a clinical trial, patients receiving selenium nanoparticles alongside standard treatments had an impressive 83.3% response rate and complete disease control.
Overall, selenium shows potential to strengthen lung cancer therapy through immune enhancement.
Read More
9
Effective selenium treatment for lung cancer
We aimed to explore the potential of selenium nanoparticles synthesized from Epimedium brevicornum in combating lung cancer. Using various techniques, we characterized these nanoparticles and evaluated their effects in both lab and live models.
Although the nanoparticles were not harmful to healthy liver cells, they effectively triggered cell death in lung cancer cells, reducing tumor growth and suppressing migration.
Our findings suggest that these selenium nanoparticles could be a promising and safe avenue for lung cancer treatment.
Although the nanoparticles were not harmful to healthy liver cells, they effectively triggered cell death in lung cancer cells, reducing tumor growth and suppressing migration.
Our findings suggest that these selenium nanoparticles could be a promising and safe avenue for lung cancer treatment.
Read More
9
Selenium nanoparticles may inhibit lung cancer
We examined how selenium nanoparticles, stabilized by Sargassum fusiforme polysaccharide, affect lung cancer cells. In lab tests, these nanoparticles were shown to inhibit the growth of A549 lung cancer cells and initiate cell apoptosis by increasing reactive oxygen species (ROS).
We also noticed that they impacted the mitochondria, altering important proteins linked to cancer cell survival. While animal studies showed a significant reduction in tumor growth without harming the animals, the potential for these nanoparticles as a viable treatment for non-small cell lung cancer seems promising.
We also noticed that they impacted the mitochondria, altering important proteins linked to cancer cell survival. While animal studies showed a significant reduction in tumor growth without harming the animals, the potential for these nanoparticles as a viable treatment for non-small cell lung cancer seems promising.
Read More
9
We explored the effectiveness of a novel selenium nanocomposite, AANL-SeNPs, in treating lung cancer. This innovative compound, created from a natural ingredient, demonstrated significant inhibition of lung cancer cell growth in various cell lines, showing up to a 67% reduction in viability.
Furthermore, AANL-SeNPs slowed tumor growth in live models and appeared safe for normal cells. While promising, our findings indicate that although AANL-SeNPs upregulate the protein CLK2 and can enhance therapeutic response, further studies are needed to fully understand its potential.
Furthermore, AANL-SeNPs slowed tumor growth in live models and appeared safe for normal cells. While promising, our findings indicate that although AANL-SeNPs upregulate the protein CLK2 and can enhance therapeutic response, further studies are needed to fully understand its potential.
Read More
9
We explored how selenium-enriched phycocyanin (Se-PC) improves photodynamic therapy for lung cancer. This combination significantly reduced the survival of lung cancer cells in mice compared to traditional treatment methods.
Our findings showed that Se-PC therapy led to a greater decrease in tumor volume and enhanced immune responses in normal tissues. Additionally, Se-PC effectively promoted cell death in cancerous cells.
Overall, while selenium has shown promise in enhancing lung cancer treatments, more research is needed to fully understand its potential benefits.
Our findings showed that Se-PC therapy led to a greater decrease in tumor volume and enhanced immune responses in normal tissues. Additionally, Se-PC effectively promoted cell death in cancerous cells.
Overall, while selenium has shown promise in enhancing lung cancer treatments, more research is needed to fully understand its potential benefits.
Read More
User Reviews
USERS' SCORE
Good
Based on 25 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Cancer prevention focus
12 people found this helpful
The antioxidant properties of selenium, especially in combination with amino acids, are significant for cancer patients. I decided to purchase it after reading Professor Tokumi Fujikawa's work, highlighting selenium's role beyond vitamin C and E. Its small, easy-to-swallow veggie capsule is advantageous. The higher ingredient content compared to Japanese supplements makes it effective. Though my cancer is nearly in remission, I will continue its use to prevent recurrence.
Read More
9
Natural cancer fighter
5 people found this helpful
Awesome! Selenium is an excellent natural fighter against cancer. These small v-caps are easy to take, and I have no complaints at all.
Read More
9
Post-cancer recovery
4 people found this helpful
My husband has taken Selenium daily for years. It aids in cancer recovery; after battling prostate cancer, he remains cancer-free four years post-treatment. He supplements with vitamin C, B12, cherry for energy, D3, and vitamin E.
Read More
9
Successful treatment
2 people found this helpful
During my breast cancer treatment, I took a 200μg selenium tablet daily. This complemented my high-protein diet. The lump diminished significantly, and post-surgery, the cancer cells were undetectable. I attribute my perseverance during chemotherapy to these supplements.
Read More
9
Immunity booster
2 people found this helpful
Excellent for keeping cancer at bay and stimulating immunity. I recommend taking it at night for relaxation and sleep. Since minerals aren't produced naturally, supplements are essential. If you're addicted to sugars, be aware that this affects your mineral levels.
Read More
Frequently Asked Questions
9
Successful treatment
2 people found this helpful
During my breast cancer treatment, I took a 200μg selenium tablet daily. This complemented my high-protein diet. The lump diminished significantly, and post-surgery, the cancer cells were undetectable. I attribute my perseverance during chemotherapy to these supplements.
9
Post-cancer recovery
4 people found this helpful
My husband has taken Selenium daily for years. It aids in cancer recovery; after battling prostate cancer, he remains cancer-free four years post-treatment. He supplements with vitamin C, B12, cherry for energy, D3, and vitamin E.
9
Cancer resistance
1 people found this helpful
Selenium offers many benefits, such as protecting the thymus and enhancing lymphocyte activity, which helps in producing antibodies. It effectively combats various illnesses, including lung cancer, earning the title "King of Anti-Cancer."
7.5
Health food benefits
1 people found this helpful
Selenium is highly beneficial for the thyroid gland, enhances the body's immunity, and possesses anti-cancer properties. It truly is one of the finest health foods!
9
Immunity booster
2 people found this helpful
Excellent for keeping cancer at bay and stimulating immunity. I recommend taking it at night for relaxation and sleep. Since minerals aren't produced naturally, supplements are essential. If you're addicted to sugars, be aware that this affects your mineral levels.
7.5
Nutritional support
12 people found this helpful
Selenium, combined with vitamin A, is effective in preventing lung cancer. This couple takes one selenium daily as part of a high-protein, low-carbohydrate regimen.
9.5
We examined the role of selenium (Se) in treating advanced non-small-cell lung cancer (NSCLC). Our research revealed that a lack of selenium leads to weakened immunity and faster tumor growth in mice. Interestingly, using selenium nanoparticles showed promising results.
These nanoparticles enhanced natural killer cell activity, boosting the immune response against cancer. In a clinical trial, patients receiving selenium nanoparticles alongside standard treatments had an impressive 83.3% response rate and complete disease control.
Overall, selenium shows potential to strengthen lung cancer therapy through immune enhancement.
These nanoparticles enhanced natural killer cell activity, boosting the immune response against cancer. In a clinical trial, patients receiving selenium nanoparticles alongside standard treatments had an impressive 83.3% response rate and complete disease control.
Overall, selenium shows potential to strengthen lung cancer therapy through immune enhancement.
8
This study aimed to investigate how selenium nanoparticles coated with bacterial polysaccharides could work as a treatment for lung cancer. We found that these nanoparticles were effective against lung adenocarcinoma cells in lab tests, showcasing strong cytotoxic effects.
However, while they showed notable antioxidant properties and supported pro-apoptotic activity, we did not find substantial improvements in lung cancer treatment efficacy compared to existing methods. Overall, the findings suggest that these nanoparticles could have potential as antimicrobial and antioxidant agents, though lung cancer benefits remain to be established.
However, while they showed notable antioxidant properties and supported pro-apoptotic activity, we did not find substantial improvements in lung cancer treatment efficacy compared to existing methods. Overall, the findings suggest that these nanoparticles could have potential as antimicrobial and antioxidant agents, though lung cancer benefits remain to be established.
8
We examined an innovative formulation, AAGL-SeNPs, created by stabilizing selenium nanoparticles with AAGL, a protein known for its strong anti-cancer properties.
In our study, this new nanocomposite demonstrated remarkable stability and safety in laboratory settings.
It not only inhibited the growth of lung cancer cells but also improved the efficacy of existing treatments like osimertinib.
Overall, AAGL-SeNPs shows promise as a potential therapeutic option for lung cancer, thanks to its ability to boost immune response and overcome treatment resistance.
In our study, this new nanocomposite demonstrated remarkable stability and safety in laboratory settings.
It not only inhibited the growth of lung cancer cells but also improved the efficacy of existing treatments like osimertinib.
Overall, AAGL-SeNPs shows promise as a potential therapeutic option for lung cancer, thanks to its ability to boost immune response and overcome treatment resistance.
References
- Fu G, Tong J. Synthesis of Epimedium extract selenium nanoparticles and evaluation their efficacy against lung cancer. Gen Physiol Biophys. 2025;44:123. 10.4149/gpb_2024046
- Yu Y, Xie B, Wang J, Luo W, Yang M, et al. Translational Selenium Nanoparticles Promotes Clinical Non-small-cell Lung Cancer Chemotherapy via Activating Selenoprotein-driven Immune Manipulation. Adv Mater. 2025. 10.1002/adma.202415818
- Shehata NS, Elwakil BH, Elshewemi SS, Ghareeb DA, Olama ZA. In vitro and in vivo studies of selenium nanoparticles coated bacterial polysaccharide as anti-lung cancer agents. Microb Cell Fact. 2024;23:339. 10.1186/s12934-024-02601-z
- Chen Y, Jin Y, Wang W, Zhang Y, Sun H, et al. Preparation and antitumor activity of selenium nanocomposite stabilized by AAGL from Agerocybe aegerita. Int J Biol Macromol. 2024;282:137002. 10.1016/j.ijbiomac.2024.137002
- Chen Y, Zhu F, Ou J, Chen J, Liu X, et al. Mitochondrion-targeted selenium nanoparticles stabilized by Sargassum fusiforme polysaccharides increase reactive oxygen species-mediated antitumour activity. Int J Biol Macromol. 2024;281:136545. 10.1016/j.ijbiomac.2024.136545
- Luo X, Wang J, Wang R, Lian J, Guo M, et al. SLL-1A-16 suppresses proliferation and induces autophagy in non-small-cell lung cancer cells the AKT/mTOR signaling pathway. RSC Med Chem. 2024;15:3460. 10.1039/d4md00405a
- Ohlinger J, Vordermark D, Ostheimer C, Bache M, Tzschoppe T, et al. Change in the serum selenium level of patients with non-metastatic and metastatic non-small cell lung cancer (NSCLC) during radiotherapy as a predictive factor for survival. Strahlenther Onkol. 2024. 10.1007/s00066-024-02276-w
- Shi H, Wang B, Ma H, Li Y, Du J, et al. Preparation of Biomimetic Selenium-Baicalein Nanoparticles and Their Targeted Therapeutic Application in Nonsmall Cell Lung Cancer. Mol Pharm. 2024;21:4476. 10.1021/acs.molpharmaceut.4c00390
- Cui B, Cheng X, Zhang X, Chen L, Pang W, et al. Anti-cancer activity and mechanism of flurbiprofen organoselenium compound RY-1-92 in non-small cell lung cancer. RSC Med Chem. 2024;15:1737. 10.1039/d4md00058g
- Zhang Y, Chen Y, Wang B, Cai Y, Zhang M, et al. A novel selenium nanocomposite modified by AANL inhibits tumor growth by upregulating CLK2 in lung cancer. Bioorg Chem. 2024;148:107459. 10.1016/j.bioorg.2024.107459
- Chen Y, Zhu F, Chen J, Liu X, Li R, et al. Selenium nanoparticles stabilized by Sargassum fusiforme polysaccharides: Synthesis, characterization and bioactivity. Int J Biol Macromol. 2024;269:132073. 10.1016/j.ijbiomac.2024.132073
- Shehata NS, Elwakil BH, Elshewemi SS, Ghareeb DA, Olama ZA. Selenium nanoparticles coated bacterial polysaccharide with potent antimicrobial and anti-lung cancer activities. Sci Rep. 2023;13:21871. 10.1038/s41598-023-48921-9
- Shen J, Xia H, Zhou X, Zhang L, Gao Q, et al. Selenium enhances photodynamic therapy of C-phycocyanin against lung cancer via dual regulation of cytotoxicity and antioxidant activity. Acta Biochim Biophys Sin (Shanghai). 2023;55:1925. 10.3724/abbs.2023159
- Zhang K, Zhu T, Quan X, Qian Y, Liu Y, et al. Association between blood heavy metals and lung cancer risk: A case-control study in China. Chemosphere. 2023;343:140200. 10.1016/j.chemosphere.2023.140200
- Zhu Y, Pu Q, Zhang Q, Liu Y, Ma Y, et al. Selenium-binding protein 1 inhibits malignant progression and induces apoptosis via distinct mechanisms in non-small cell lung cancer. Cancer Med. 2023;12:17149. 10.1002/cam4.6309
- Lubiński J, Lener MR, Marciniak W, Pietrzak S, Derkacz R, et al. Serum Essential Elements and Survival after Cancer Diagnosis. Nutrients. 2023;15. 10.3390/nu15112611
