Last update
10/4/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
5.9
USERS' SCORE
Good
Based on 4 Reviews
8.2
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin A (from Retinyl Palmitate and Fish Liver Oil)
3,000 mcg
333%
Top Medical Research Studies
9
We investigated the impact of vitamin A in treating heart disease, specifically after a myocardial infarction (MI). Our study focused on over 150 cardiac surgery patients, with a particular emphasis on the effects of vitamin A on bone marrow stem cells. We discovered that MI led to harmful changes in these stem cells and that vitamin A, specifically its metabolite 4-oxo-retinoic acid, helps reduce inflammation by calming the stem cells. This approach could improve heart function in the long run after an MI.
Read More
9
We examined how retinoic acid (a form of vitamin A) could promote the repair of heart tissue after injury. Through the use of self-assembling peptides to deliver retinoic acid, we found that it effectively increased the proliferation of heart cells in rats. This treatment also boosted the expression of key genes associated with heart regeneration and improved heart function within four weeks. Overall, our findings suggest that retinoic acid might be a promising strategy to enhance the recovery of damaged heart tissue.
Read More
7
We explored how vitamin A influences heart health in mice with diet-induced obesity. Through a study comparing genetically altered mice with vitamin A deficiencies to normal mice fed a vitamin A-sufficient diet, we found that, despite vitamin A deficiency, the heart's structure, function, and energy production capabilities remained intact after 20 weeks.
Our findings revealed that vitamin A is crucial in maintaining heart-related gene expression linked to energy processes. While the results suggest vitamin A's significant role in preserving cardiac function, they did not indicate a direct benefit in reversing or preventing heart disease in this obesity model.
Our findings revealed that vitamin A is crucial in maintaining heart-related gene expression linked to energy processes. While the results suggest vitamin A's significant role in preserving cardiac function, they did not indicate a direct benefit in reversing or preventing heart disease in this obesity model.
Read More
Most Useful Reviews
9
Relieves heart attacks
2 people found this helpful
I found that after taking this vitamin, my nails strengthened and skin improved within weeks. Although I cannot gauge the effects on my immunity, my heart issues have vanished, especially after I began taking Omega 3. After two packs, I have no regrets about my purchase.
Read More
7.5
Excellent quality
The quality is excellent and very good. The benefits are substantial, particularly for heart health, hair, and overall bodily wellness. It is suitable for all ages.
Read More
6
Helps with skin disease
I take this vitamin as advised by my doctor during skin disease flare-ups, and it seems to aid in my treatment.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
5.9
- All Researches
9
We investigated the impact of vitamin A in treating heart disease, specifically after a myocardial infarction (MI). Our study focused on over 150 cardiac surgery patients, with a particular emphasis on the effects of vitamin A on bone marrow stem cells. We discovered that MI led to harmful changes in these stem cells and that vitamin A, specifically its metabolite 4-oxo-retinoic acid, helps reduce inflammation by calming the stem cells. This approach could improve heart function in the long run after an MI.
Read More
9
We examined how retinoic acid (a form of vitamin A) could promote the repair of heart tissue after injury. Through the use of self-assembling peptides to deliver retinoic acid, we found that it effectively increased the proliferation of heart cells in rats. This treatment also boosted the expression of key genes associated with heart regeneration and improved heart function within four weeks. Overall, our findings suggest that retinoic acid might be a promising strategy to enhance the recovery of damaged heart tissue.
Read More
8
We examined the connection between serum retinol levels, a marker for vitamin A, and long-term mortality over 30 years. Our analysis involved nearly 29,000 men and revealed that those with higher retinol levels had a 17-32% lower risk of dying from heart disease and other causes compared to those with lower levels.
Interestingly, this beneficial effect held true across various groups, regardless of smoking, drinking, or weight. Although higher retinol is linked to lower mortality, it's important to note that factors like smoking and diabetes played a minimal role in mediation through retinol levels.
Interestingly, this beneficial effect held true across various groups, regardless of smoking, drinking, or weight. Although higher retinol is linked to lower mortality, it's important to note that factors like smoking and diabetes played a minimal role in mediation through retinol levels.
Read More
7
We explored how vitamin A influences heart health in mice with diet-induced obesity. Through a study comparing genetically altered mice with vitamin A deficiencies to normal mice fed a vitamin A-sufficient diet, we found that, despite vitamin A deficiency, the heart's structure, function, and energy production capabilities remained intact after 20 weeks.
Our findings revealed that vitamin A is crucial in maintaining heart-related gene expression linked to energy processes. While the results suggest vitamin A's significant role in preserving cardiac function, they did not indicate a direct benefit in reversing or preventing heart disease in this obesity model.
Our findings revealed that vitamin A is crucial in maintaining heart-related gene expression linked to energy processes. While the results suggest vitamin A's significant role in preserving cardiac function, they did not indicate a direct benefit in reversing or preventing heart disease in this obesity model.
Read More
4
We analyzed data from 7,341 adults aged 65 and older to see how various nutrients affect heart disease.
Our findings revealed that vitamin A, along with other nutrients, was connected with lower heart disease prevalence. Specifically, higher intake of vitamin A was associated with a 5% decrease in risk, among other beneficial effects we noted for different nutrients.
However, while there are some associations, it's crucial to understand that the study found no strong or direct causal relationship between vitamin A and heart disease prevention.
Our findings revealed that vitamin A, along with other nutrients, was connected with lower heart disease prevalence. Specifically, higher intake of vitamin A was associated with a 5% decrease in risk, among other beneficial effects we noted for different nutrients.
However, while there are some associations, it's crucial to understand that the study found no strong or direct causal relationship between vitamin A and heart disease prevention.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Relieves heart attacks
2 people found this helpful
I found that after taking this vitamin, my nails strengthened and skin improved within weeks. Although I cannot gauge the effects on my immunity, my heart issues have vanished, especially after I began taking Omega 3. After two packs, I have no regrets about my purchase.
Read More
7.5
Excellent quality
The quality is excellent and very good. The benefits are substantial, particularly for heart health, hair, and overall bodily wellness. It is suitable for all ages.
Read More
6
Helps with skin disease
I take this vitamin as advised by my doctor during skin disease flare-ups, and it seems to aid in my treatment.
Read More
7.5
Protects heart health
4 people found this helpful
Ensuring an adequate intake of vitamin A is crucial for maintaining eye, skin, and heart health. This product serves its purpose effectively at a reasonable price from a trusted company.
Read More
Frequently Asked Questions
9
Relieves heart attacks
2 people found this helpful
I found that after taking this vitamin, my nails strengthened and skin improved within weeks. Although I cannot gauge the effects on my immunity, my heart issues have vanished, especially after I began taking Omega 3. After two packs, I have no regrets about my purchase.
7.5
Excellent quality
The quality is excellent and very good. The benefits are substantial, particularly for heart health, hair, and overall bodily wellness. It is suitable for all ages.
6
Helps with skin disease
I take this vitamin as advised by my doctor during skin disease flare-ups, and it seems to aid in my treatment.
7.5
Protects heart health
4 people found this helpful
Ensuring an adequate intake of vitamin A is crucial for maintaining eye, skin, and heart health. This product serves its purpose effectively at a reasonable price from a trusted company.
4
We analyzed data from 7,341 adults aged 65 and older to see how various nutrients affect heart disease.
Our findings revealed that vitamin A, along with other nutrients, was connected with lower heart disease prevalence. Specifically, higher intake of vitamin A was associated with a 5% decrease in risk, among other beneficial effects we noted for different nutrients.
However, while there are some associations, it's crucial to understand that the study found no strong or direct causal relationship between vitamin A and heart disease prevention.
Our findings revealed that vitamin A, along with other nutrients, was connected with lower heart disease prevalence. Specifically, higher intake of vitamin A was associated with a 5% decrease in risk, among other beneficial effects we noted for different nutrients.
However, while there are some associations, it's crucial to understand that the study found no strong or direct causal relationship between vitamin A and heart disease prevention.
8
We examined the connection between serum retinol levels, a marker for vitamin A, and long-term mortality over 30 years. Our analysis involved nearly 29,000 men and revealed that those with higher retinol levels had a 17-32% lower risk of dying from heart disease and other causes compared to those with lower levels.
Interestingly, this beneficial effect held true across various groups, regardless of smoking, drinking, or weight. Although higher retinol is linked to lower mortality, it's important to note that factors like smoking and diabetes played a minimal role in mediation through retinol levels.
Interestingly, this beneficial effect held true across various groups, regardless of smoking, drinking, or weight. Although higher retinol is linked to lower mortality, it's important to note that factors like smoking and diabetes played a minimal role in mediation through retinol levels.
9
We investigated the impact of vitamin A in treating heart disease, specifically after a myocardial infarction (MI). Our study focused on over 150 cardiac surgery patients, with a particular emphasis on the effects of vitamin A on bone marrow stem cells. We discovered that MI led to harmful changes in these stem cells and that vitamin A, specifically its metabolite 4-oxo-retinoic acid, helps reduce inflammation by calming the stem cells. This approach could improve heart function in the long run after an MI.
2
We assessed how various maternal factors impact the risk of congenital heart defects (CHD) in children using extensive data from the Japan Environment and Children's Study.
Our analysis of over 91,000 births revealed that certain factors, including maternal age over 40 and the use of vitamin A supplements, were related to an increased risk of CHD.
Notably, mothers taking vitamin A supplements showed a significant association with CHD in their offspring, suggesting the need for further scrutiny regarding maternal nutrition and medication during early pregnancy.
Our analysis of over 91,000 births revealed that certain factors, including maternal age over 40 and the use of vitamin A supplements, were related to an increased risk of CHD.
Notably, mothers taking vitamin A supplements showed a significant association with CHD in their offspring, suggesting the need for further scrutiny regarding maternal nutrition and medication during early pregnancy.
References
- Li W, Liu S, Meng X, Liu H. A nutrient wide association study of cardiovascular disease prevalence in older adults from NHANES 2007 to 2018. Sci Rep. 2025;15:12710. 10.1038/s41598-025-97143-8
- Rettkowski J, Romero-Mulero MC, Singh I, Wadle C, Wrobel J, et al. Modulation of bone marrow haematopoietic stem cell activity as a therapeutic strategy after myocardial infarction: a preclinical study. Nat Cell Biol. 2025;27:591. 10.1038/s41556-025-01639-4
- Kawai S, Pak K, Iwamoto S, Kawakami C, Inuzuka R, et al. Association Between Maternal Factors in Early Pregnancy and Congenital Heart Defects in Offspring: The Japan Environment and Children's Study. J Am Heart Assoc. 2023;12:e029268. 10.1161/JAHA.122.029268
- Tan YZ, Shen HR, Wang YL, Wang QL, Wu XP, et al. Retinoic acid released from self-assembling peptide activates cardiomyocyte proliferation and enhances repair of infarcted myocardium. Exp Cell Res. 2023;422:113440. 10.1016/j.yexcr.2022.113440
- Naasner L, Froese N, Hofmann W, Galuppo P, Werlein C, et al. Vitamin A preserves cardiac energetic gene expression in a murine model of diet-induced obesity. Am J Physiol Heart Circ Physiol. 2022;323:H1352. 10.1152/ajpheart.00514.2022
- Huang J. Circulating Concentrations of Nutrition-Related Factors Are Not Causally Associated With Atrial Fibrillation: A Mendelian Randomization Study. J Cardiovasc Pharmacol. 2022;80:210. 10.1097/FJC.0000000000001263
- Huang J, Weinstein SJ, Yu K, Männistö S, Albanes D. Association between serum retinol and overall and cause-specific mortality in a 30-year prospective cohort study. Nat Commun. 2021;12:6418. 10.1038/s41467-021-26639-4
