NOW Supplements Glucosamine & Chondroitin with MSM

Supplement Facts

Serving Size: 3 Veg Capsules

Amount Per Serving

%DV

Calories

Total Carbohydrate

2 g

<1%**

Sodium

150 mg

Glucosamine Sulfate(from 1,500 mg Glucosamine PotassiumSulfate Complex)

1.1 g (1,100 mg)

†

Chondroitin Sodium Sulfate(from Bovine Cartilage)

1.2 g (1,200 mg)

†

MSM (Methylsulfonylmethane)

300 mg

†

The product is found useful for the following medical conditions

Collagen-induced arthritis: severity and immune response attenuation using multivalent N-acetyl glucosamine.

Most Relevant Research

We aimed to understand how N-acetyl glucosamine (GlcNAc), a compound known for its anti-inflammatory properties, affects the development and severity of collagen-induced arthritis (CIA). Our investigation involved applying a special multivalent GlcNAc-terminated glycoconjugate and assessing its influence through various methodologies.

The results were promising. We observed that GlcNAc treatment significantly reduced inflammation at the site of arthritis, notably decreasing the presence of immune cells that contribute to the disease. Furthermore, it appeared to hinder the activation of other immune cells, which are often involved in the production of harmful pro-inflammatory molecules.

Additionally, GlcNAc treatment not only delayed the onset of arthritis symptoms but also eased the severity of these symptoms in many cases. We found that about 18% to 31% of participants treated with GlcNAc completely avoided any arthritis symptoms. Overall, our findings support a new approach to managing arthritis by focusing on the glycobiological aspects of treatment, presenting GlcNAc as a potential therapeutic option for those suffering from this debilitating condition.

9.5

Immediate results

Most Useful Review

Noticed a difference the very next day! After experiencing severe pain, I was informed I have onset arthritis. I researched natural supplements and found this product. I took three capsules upon arrival and the next day, my pain reduced significantly from an 8 to a 2, with improved mobility. I am optimistic about further improvements.

Back Pain details

Back pain improvement

Most Useful Review

After a year of high-dose usage, I have experienced a significant reduction in the severity of my back problems, more effective than years of strengthening and chiropractic care alone.

Bursitis details

I take my son. After an injury and subsequent purulent bursitis in the knee joint, the joint hurts during physical exertion. This drug helps him, and there is no pain.

Common Cold details

Helped to cope with knee pain. I acquired this medication on recommendation. In winter, I experienced knee difficulties, unable to bend or straighten, leading to considerable discomfort while walking. The exacerbation period lasted two weeks, but the pain does return occasionally. After a month’s course, I've noticed significant improvement; now, the knee only aches in the cold. Doctors found no issues and prescribed nothing. When I inquired about taking chondroitin, they unanimously deemed it unnecessary. However, I do not regret taking it. In the autumn, I intend to complete the full course, needing three jars. At its initial, non-neglected stage, it proves very effective.

Gout details

SCIENTIFIC SCORE

Moderately Effective

Based on 2 Researches

MSM shows promise for gout treatment

Modified Simiaowan prevents and treats gouty arthritis via the Nrf2/NLRP3 inflammasome signaling pathway.

Most Relevant Research

This study aimed to explore how Modified Simiaowan (MSM), a traditional six-herb formula, can help treat gouty arthritis (GA). We examined its effects on macrophages in the lab, as well as in animal models with induced gout. Using various techniques, we analyzed the inflammation response and the underlying biological pathways affected by MSM.

Through our research, we observed that MSM has strong anti-inflammatory and antioxidant properties. It seems to alleviate the symptoms of gouty arthritis by interacting with specific signaling pathways in the body, particularly the Nrf2/HO-1/ROS/NLRP3 pathway. This means that MSM not only reduces inflammation but also helps the body combat oxidative stress, which is significant in managing gout.

Overall, our findings suggest that MSM could be a promising natural solution for those struggling with gouty arthritis, providing relief through a multi-faceted approach to treatment. The study bridges traditional herbal remedies with modern scientific understanding, highlighting the potential benefits of integrating such treatments into healthcare for gout.

9.5

Quick inflammation relief

Most Useful Review

Fantastic! My father has gout, and this product rapidly reduced the inflammation in his joint when his condition worsened.

Heart Disease details

Preventative joint support

Most Useful Review

100% WORKS, effective both in treatment and prevention! I've encountered much contradictory information regarding Glucosamine & Chondroitin. I, too, have experienced age-related changes whilst participating in sports. After a month on Glucosamine & Chondroitin with MSM, I saw remarkable results; the crunch in my knees diminished, and my joints felt stronger. Additionally, I enjoyed better sleep quality, and it even helped with hemorrhoids. I always aim to provide honest reviews to assist others.

Sleep Apnea details

Improved sleep quality

Most Useful Review

This is not the first time we've taken this with the girls, and all of them have shown very positive results. Those who often suffer from headaches found that the pain has ceased. I now experience vigour during the day and restful sleep at night. My dreams have become more vivid.

Swollen Lymph Nodes details

Joint swelling reduced

Most Useful Review

Great results! My family takes it on the recommendation of our chiropractor. We make sure to take it for at least four weeks, and after eight days of use, my mother noticed her joint swelling had diminished.

Chronic Cough details

This very good product is reputed to be capable of rebuilding joints. Since I have chronic Lyme disease and my joints are always an issue, I take these 3-6 times a day, and they are helping me immensely. I would recommend them to anyone with joint problems; they are truly amazing.

Ear Infection details

My mother, in her early 50s, lamented her knee pain. Unable to afford Japanese products, I searched online and purchased these instead. My mother struggles with pills, but she tolerates the large grains. Interestingly, after consuming about half a bottle, she no longer complains of knee pain! Although she only takes 2 tablets in 2 days, the desired effect is achieved. There are no side effects, and the product is very trustworthy. If you're concerned about your parents, I encourage you to try it.

Athlete’s Foot details

Significant pain reduction

Most Useful Review

I’ve dealt with foot pain for four years with no help from doctors. After taking this supplement for a month, I have drastically reduced my reliance on painkillers. My leg complains much less frequently now, and I will definitely continue purchasing this product in the future.

Blood Clot details

Joint crunching alleviated

Most Useful Review

Glucosamine and chondroitin positively influence joint health, particularly in alleviating knee crunching. I took one capsule twice daily after meals for several months annually. The process improved, as glucosamine helps cartilage recover. I combined this regimen with collagen and vitamin D, while also moderating salt intake to prevent blood pressure issues. There were no side effects noted, and I saw improvements in my joint health. I highly recommend this supplement for its effectiveness.

Chronic Fatigue Syndrome details

The quality is superb. The ingredients in one capsule have an excellent effect on my health. I take courses in the autumn and spring, and as a result, I have stopped suffering from chronic fatigue syndrome. The size of the capsule is standard, and it has no smell. The benefits are noticeable after completing the intake.

High Cholesterol details

Positive joint support

Most Useful Review

Great Product! I’ve been using this for about a year, and I feel it has positively impacted my joints. When I miss doses for about two months, my joints become stiff and slow to move. I highly recommend this product.

Autoimmune Disorder details

Joint health improvement

Most Useful Review

This product effectively maintains joint health. Previously, I had ordered from other companies, but the results diminished. I read the composition carefully and found this one met the ideal glucosamine and chondroitin ratio. After a month, my joints have stopped crackling, and I've noticed improvements in my skin's elasticity as well.

Food Poisoning details

Joint relief experienced

Most Useful Review

I prefer the liquid form from NOW Foods! The results on my daughter's joints were immediate. Her crunching joints decreased after taking it, and it noticeably lifted her mood. Moreover, it aids in restoring damage caused by metabolic issues, supporting cartilage integrity and resilience under pressure. It's an effective health solution!

Frozen Shoulder details

Shoulder pain reduction

Most Useful Review

Compared with pharmacy chondroprotectors, this product is simply excellent in both price and quality. My chronic shoulder pains have nearly subsided, allowing me to press fully on without discomfort.

Rash details

First, I purchased it for my father, who suffers from arthritis, and he subsequently requested it for a friend. There is indeed an effect, but it's noticeable after approximately three weeks. The formulation has a good composition and appropriate dosage of its key ingredients. The inclusion of sulphur (MCM) provided a pleasant side effect; after a week of usage, my face cleared up as I had been experiencing rashes. We’ve concluded that the sulphur is beneficial for this issue, so we continue to buy this supplement during flare-ups.

Allergies details

SCIENTIFIC SCORE

Likely Very Effective

MSM offers allergy symptom relief

Evaluating the Impacts of Methylsulfonylmethane on Allergic Rhinitis After a Standard Allergen Challenge: Randomized Double-Blind Exploratory Study.

Most Relevant Research

We aimed to understand how methylsulfonylmethane (MSM) impacts symptoms of allergic rhinitis through a well-structured randomized, double-blind study.

Participants, who were prone to allergic responses, were tested after taking varying doses of MSM following allergen exposure.

Interestingly, the results showed that MSM significantly eased nasal symptoms and improved airflow, making it a potential alternative to conventional allergy medications.

We’re excited by the findings, as MSM appeared effective without common side effects associated with typical treatments.

9.5

No allergies experienced

Most Useful Review

Glucosamine & Chondroitin with MSM has been a great help for my joints! I opted for this product from Now Foods, having had good experiences with them before. The capsules are large and white, and I found them easy to swallow, even when required three times a day. I didn’t experience any side effects like swelling or stomach issues that some others reported, possibly due to the stabilisation with potassium sulfate. I found this product effective in lubricating my joints with no allergic reactions. Overall, I would recommend it for its quality and effectiveness.