' 
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 3 Reviews
8.6
Supplement Facts
Serving Size: 3 Veg Capsules
Amount Per Serving
%DV
Calories
10
Total Carbohydrate
2 g
<1%**
Sodium
150 mg
7%
Glucosamine Sulfate(from 1,500 mg Glucosamine PotassiumSulfate Complex)
1.1 g (1,100 mg)
†
Chondroitin Sodium Sulfate(from Bovine Cartilage)
1.2 g (1,200 mg)
†
MSM (Methylsulfonylmethane)
300 mg
†
Top Medical Research Studies
9
MSM shows promise for gout treatment
Modified Simiaowan prevents and treats gouty arthritis via the Nrf2/NLRP3 inflammasome signaling pathway.
Direct investigation of MSM impacts
This study aimed to explore how Modified Simiaowan (MSM), a traditional six-herb formula, can help treat gouty arthritis (GA). We examined its effects on macrophages in the lab, as well as in animal models with induced gout. Using various techniques, we analyzed the inflammation response and the underlying biological pathways affected by MSM.
Through our research, we observed that MSM has strong anti-inflammatory and antioxidant properties. It seems to alleviate the symptoms of gouty arthritis by interacting with specific signaling pathways in the body, particularly the Nrf2/HO-1/ROS/NLRP3 pathway. This means that MSM not only reduces inflammation but also helps the body combat oxidative stress, which is significant in managing gout.
Overall, our findings suggest that MSM could be a promising natural solution for those struggling with gouty arthritis, providing relief through a multi-faceted approach to treatment. The study bridges traditional herbal remedies with modern scientific understanding, highlighting the potential benefits of integrating such treatments into healthcare for gout.
Through our research, we observed that MSM has strong anti-inflammatory and antioxidant properties. It seems to alleviate the symptoms of gouty arthritis by interacting with specific signaling pathways in the body, particularly the Nrf2/HO-1/ROS/NLRP3 pathway. This means that MSM not only reduces inflammation but also helps the body combat oxidative stress, which is significant in managing gout.
Overall, our findings suggest that MSM could be a promising natural solution for those struggling with gouty arthritis, providing relief through a multi-faceted approach to treatment. The study bridges traditional herbal remedies with modern scientific understanding, highlighting the potential benefits of integrating such treatments into healthcare for gout.
Read More
8
Glucosamine linked to lower gout risk
Associations of habitual glucosamine supplementation with incident gout: a large population based cohort study.
Important but incomplete findings
We examined the relationship between glucosamine use and the risk of developing gout among a large population of participants. The study included 436,594 individuals, primarily from the UK Biobank, who were asked about their supplementation habits, specifically focusing on glucosamine. Notably, this analysis targeted those who did not have a history of gout at the start.
Findings revealed that 22% of females and 16% of males reported using glucosamine regularly. Over a follow-up period of about 12 years, we observed that a significant number of participants developed gout. However, the results indicated a fascinating trend: while habitual glucosamine use was linked to a reduced risk of gout in females (with a hazard ratio of 0.81), there was no such association found for males (hazard ratio of 1.05).
What’s particularly interesting is that this protective effect in women was even stronger for those taking diuretics. This suggests that glucosamine supplementation might play a more beneficial role for specific groups within the population. Overall, our findings point towards a potential gender-specific impact of glucosamine on gout, highlighting the need for further research in this area.
Findings revealed that 22% of females and 16% of males reported using glucosamine regularly. Over a follow-up period of about 12 years, we observed that a significant number of participants developed gout. However, the results indicated a fascinating trend: while habitual glucosamine use was linked to a reduced risk of gout in females (with a hazard ratio of 0.81), there was no such association found for males (hazard ratio of 1.05).
What’s particularly interesting is that this protective effect in women was even stronger for those taking diuretics. This suggests that glucosamine supplementation might play a more beneficial role for specific groups within the population. Overall, our findings point towards a potential gender-specific impact of glucosamine on gout, highlighting the need for further research in this area.
Read More
Most Useful Reviews
9.5
Quick inflammation relief
Fantastic! My father has gout, and this product rapidly reduced the inflammation in his joint when his condition worsened.
Read More
8.3
Improved joint mobility
My mother has rheumatoid arthritis and gout. After she took chondroitin, vitamin D3, and calcium citrate, the pain in her joints decreased significantly. She returned to normal mobility. I will definitely reorder as soon as the medication becomes available.
Read More
8.8
Eased gout attacks
I gave this to my stepfather, who suffers from severe gout attacks that can last for weeks. Though the doctor prescribed Arthra, its price and effectiveness were disappointing. Nevertheless, Arthra helped him tolerate the attacks better. We decided to try this new drug and have no regrets. The strongest attack he experienced this year lasted only three days and was managed much more easily than usual. This indicates that the medication works, especially as he takes it alongside cherry extract. I give it a solid rating and will order more.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
- All Researches
9
MSM shows promise for gout treatment
Modified Simiaowan prevents and treats gouty arthritis via the Nrf2/NLRP3 inflammasome signaling pathway.
Direct investigation of MSM impacts
This study aimed to explore how Modified Simiaowan (MSM), a traditional six-herb formula, can help treat gouty arthritis (GA). We examined its effects on macrophages in the lab, as well as in animal models with induced gout. Using various techniques, we analyzed the inflammation response and the underlying biological pathways affected by MSM.
Through our research, we observed that MSM has strong anti-inflammatory and antioxidant properties. It seems to alleviate the symptoms of gouty arthritis by interacting with specific signaling pathways in the body, particularly the Nrf2/HO-1/ROS/NLRP3 pathway. This means that MSM not only reduces inflammation but also helps the body combat oxidative stress, which is significant in managing gout.
Overall, our findings suggest that MSM could be a promising natural solution for those struggling with gouty arthritis, providing relief through a multi-faceted approach to treatment. The study bridges traditional herbal remedies with modern scientific understanding, highlighting the potential benefits of integrating such treatments into healthcare for gout.
Through our research, we observed that MSM has strong anti-inflammatory and antioxidant properties. It seems to alleviate the symptoms of gouty arthritis by interacting with specific signaling pathways in the body, particularly the Nrf2/HO-1/ROS/NLRP3 pathway. This means that MSM not only reduces inflammation but also helps the body combat oxidative stress, which is significant in managing gout.
Overall, our findings suggest that MSM could be a promising natural solution for those struggling with gouty arthritis, providing relief through a multi-faceted approach to treatment. The study bridges traditional herbal remedies with modern scientific understanding, highlighting the potential benefits of integrating such treatments into healthcare for gout.
Read More
8
Glucosamine linked to lower gout risk
Associations of habitual glucosamine supplementation with incident gout: a large population based cohort study.
Important but incomplete findings
We examined the relationship between glucosamine use and the risk of developing gout among a large population of participants. The study included 436,594 individuals, primarily from the UK Biobank, who were asked about their supplementation habits, specifically focusing on glucosamine. Notably, this analysis targeted those who did not have a history of gout at the start.
Findings revealed that 22% of females and 16% of males reported using glucosamine regularly. Over a follow-up period of about 12 years, we observed that a significant number of participants developed gout. However, the results indicated a fascinating trend: while habitual glucosamine use was linked to a reduced risk of gout in females (with a hazard ratio of 0.81), there was no such association found for males (hazard ratio of 1.05).
What’s particularly interesting is that this protective effect in women was even stronger for those taking diuretics. This suggests that glucosamine supplementation might play a more beneficial role for specific groups within the population. Overall, our findings point towards a potential gender-specific impact of glucosamine on gout, highlighting the need for further research in this area.
Findings revealed that 22% of females and 16% of males reported using glucosamine regularly. Over a follow-up period of about 12 years, we observed that a significant number of participants developed gout. However, the results indicated a fascinating trend: while habitual glucosamine use was linked to a reduced risk of gout in females (with a hazard ratio of 0.81), there was no such association found for males (hazard ratio of 1.05).
What’s particularly interesting is that this protective effect in women was even stronger for those taking diuretics. This suggests that glucosamine supplementation might play a more beneficial role for specific groups within the population. Overall, our findings point towards a potential gender-specific impact of glucosamine on gout, highlighting the need for further research in this area.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Quick inflammation relief
Fantastic! My father has gout, and this product rapidly reduced the inflammation in his joint when his condition worsened.
8.3
Improved joint mobility
My mother has rheumatoid arthritis and gout. After she took chondroitin, vitamin D3, and calcium citrate, the pain in her joints decreased significantly. She returned to normal mobility. I will definitely reorder as soon as the medication becomes available.
8.8
Eased gout attacks
I gave this to my stepfather, who suffers from severe gout attacks that can last for weeks. Though the doctor prescribed Arthra, its price and effectiveness were disappointing. Nevertheless, Arthra helped him tolerate the attacks better. We decided to try this new drug and have no regrets. The strongest attack he experienced this year lasted only three days and was managed much more easily than usual. This indicates that the medication works, especially as he takes it alongside cherry extract. I give it a solid rating and will order more.
Read More
