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During the trials, we observed that the urolithiasis model led to a troubling decrease in essential kidney health indicators such as urinary magnesium levels and specific antioxidant activities, including glutathione and catalase. Additionally, we noted an increase in harmful substances that often contribute to stone formation, like calcium and oxalate crystals.
Interestingly, treatment with either the emulsion or the nanogel significantly improved these kidney indicators. It elevated glutathione levels and reduced the formation of oxalate crystals, all while enhancing kidney function. The nanogel version of the extracts showed even better results compared to the traditional emulsion, suggesting a promising avenue for further research.
In conclusion, our findings indicate that the extracts from C. proximus and P. crispum can indeed assist in protecting against kidney stones by supporting kidney function and minimizing unhealthy kidney changes. While glutathione played a role in this context, it was part of a broader treatment strategy, making its isolated effects harder to pinpoint.
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During the trials, we observed that the urolithiasis model led to a troubling decrease in essential kidney health indicators such as urinary magnesium levels and specific antioxidant activities, including glutathione and catalase. Additionally, we noted an increase in harmful substances that often contribute to stone formation, like calcium and oxalate crystals.
Interestingly, treatment with either the emulsion or the nanogel significantly improved these kidney indicators. It elevated glutathione levels and reduced the formation of oxalate crystals, all while enhancing kidney function. The nanogel version of the extracts showed even better results compared to the traditional emulsion, suggesting a promising avenue for further research.
In conclusion, our findings indicate that the extracts from C. proximus and P. crispum can indeed assist in protecting against kidney stones by supporting kidney function and minimizing unhealthy kidney changes. While glutathione played a role in this context, it was part of a broader treatment strategy, making its isolated effects harder to pinpoint.
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Frequently Asked Questions
Kidney stones are hard deposits made of minerals and salts that form inside your kidneys. While they can vary in size from tiny particles to large stones, they all begin as crystallized substances that develop when urine contains more crystal-forming substances than the fluid in your urine can dilute. When the crystals stick together, they can form stones, which may cause severe pain, especially when they pass through the urinary tract. Common types of kidney stones include calcium stones, struvite stones, uric acid stones, and cystine stones.
The symptoms of kidney stones can include sharp pain in the side and back, pain during urination, pink or red urine, and frequent urination. Various factors can increase the risk of developing kidney stones, including dehydration, certain dietary choices, and genetic predisposition. Preventing kidney stones often involves drinking plenty of water, avoiding excessive salt and animal protein, and ensuring a balanced intake of calcium. For those who suffer from kidney stones, a medical evaluation may be necessary to determine the best management and preventive strategies.
L-glutathione is a powerful antioxidant that plays a crucial role in cellular health by protecting cells from oxidative stress and damage caused by free radicals. It is a tripeptide composed of three amino acids: cysteine, glutamine, and glycine. Naturally produced in the body, L-glutathione is found in higher concentrations in the liver, where it aids in detoxification processes, immune system function, and the metabolism of various compounds. As we age or face various environmental stresses, our body's levels of glutathione may decrease, leading to potential health implications.
This supplement, specifically extracts from Cymbopogon proximus and Petroselinum crispum, shows promising potential in supporting kidney health and reducing the formation of kidney stones, according to a study that rigorously examined its effects in a rat model [1]. The research indicated that treatment with these extracts improved essential kidney indicators, such as urinary magnesium levels and antioxidant activities. This suggests that the extracts may help in mitigating harmful substances that contribute to stone formation, particularly by reducing oxalate crystals.
Moreover, the study highlighted the effectiveness of these supplements in enhancing kidney function, noting that the nanogel form outperformed the emulsion version in its protective roles [1]. While further studies are warranted to fully understand the nuances of their effectiveness and the role of glutathione within a broader treatment strategy, the initial findings are encouraging for those interested in natural approaches to preventing kidney stones.
User reviews indicate that while some individuals have experienced positive outcomes from using the product, particularly when recommended by friends or family, there are significant concerns regarding dosage and side effects. For instance, several users report that taking the recommended dosage led to adverse effects on kidney function, suggesting that careful monitoring and staying hydrated is advisable. One user noted that the results were promising, particularly with a recommendation from a sister, but they also highlighted an experience of negative kidney effects after taking two pills daily (Read Review).
On the other hand, not every user experienced benefits, with some feeling like the product primarily served to cleanse the kidneys without noticeable improvements in their health or symptoms (Read Review). This variance suggests that while there may be potential for symptom improvement, individual experiences can differ widely, with some users advising caution when it comes to dosage and the necessity of hydration to mitigate any adverse effects.
Users report that when combining this supplement with other products for managing kidney stones, careful attention to dosage is essential. Several individuals have highlighted experiences of negative effects on kidney function after taking the recommended dosage of two pills daily, suggesting that it might be beneficial to monitor overall intake closely (Read Review). Additionally, one user specifically mentioned that the results were promising but also cautioned against high dosages, recommending that users stay hydrated to mitigate any adverse impacts on kidney health (Read Review).
Furthermore, not all users have found success with this supplement, with some feeling the product primarily acted as a kidney cleanser without noticeable symptom relief (Read Review). This variance in experiences underscores the need for users to approach combining supplements with caution and to consider the unique responses of their bodies, particularly with respect to kidney function.
Based on user reviews, there seems to be a consensus on the need for caution when determining the right dosage of L Glutathione for treating kidney stones. Many users reported negative impacts on kidney function when taking higher doses, specifically two pills daily, suggesting that overconsumption could lead to undesirable effects. One user mentioned that after taking two pills a day, they experienced issues with their kidneys and advised others to be cautious about dosages and to ensure adequate water intake ((Read Review)). Another reviewer echoed similar sentiments, noting that their kidney health was affected after taking two pills daily ((Read Review)).
On the other hand, while some users reported promising results with L Glutathione, it's clear that more experimentation is necessary to pinpoint an ideal dosage that is both effective and safe for kidney health. One user simply noted that the product seems to clean the kidneys but fails to deliver significant results ((Read Review)). Overall, the evidence suggests starting with a lower dose and monitoring your body's response could be wise until more definitive guidelines are established.
During the trials, we observed that the urolithiasis model led to a troubling decrease in essential kidney health indicators such as urinary magnesium levels and specific antioxidant activities, including glutathione and catalase. Additionally, we noted an increase in harmful substances that often contribute to stone formation, like calcium and oxalate crystals.
Interestingly, treatment with either the emulsion or the nanogel significantly improved these kidney indicators. It elevated glutathione levels and reduced the formation of oxalate crystals, all while enhancing kidney function. The nanogel version of the extracts showed even better results compared to the traditional emulsion, suggesting a promising avenue for further research.
In conclusion, our findings indicate that the extracts from C. proximus and P. crispum can indeed assist in protecting against kidney stones by supporting kidney function and minimizing unhealthy kidney changes. While glutathione played a role in this context, it was part of a broader treatment strategy, making its isolated effects harder to pinpoint.
References
- Essa HA, Ali AM, Saied MA. Cymbopogon proximus and Petroselinum crispum seed ethanolic extract/Gum Arabic nanogel emulsion: Preventing ethylene glycol and ammonium chloride-induced urolithiasis in rats. Urolithiasis. 2024;52:52. doi:10.1007/s00240-024-01559-2
