Can NOW Supplements Hyaluronic Acid Help with Bone Pain?
Research Authors
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 25 Reviews
8.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Sodium (from Sodium Hyaluronate)
10 mg
< 1 %
Hyaluronic Acid (from Sodium Hyaluronate)
100 mg
†
L-Proline (Free-Form)
100 mg
†
Alpha Lipoic Acid
50 mg
†
Grape Seed Extract (Vitis vinifera)(Standardized for Polyphenols)
25 mg
†
Top Medical Research Studies
8
Polynucleotide sodium reduces knee pain
Pilot Study to Evaluate the Efficacy of Polynucleotide Sodium Compared to Sodium Hyaluronate and Crosslinked Sodium Hyaluronate in Patients with Knee Osteoarthritis.
We engaged in a pilot study comparing the effectiveness of polynucleotide sodium with sodium hyaluronate for knee osteoarthritis pain relief. With 15 patients divided into three groups, all received ultrasound-guided injections over three weeks.
Our findings showed that those treated with polynucleotide sodium experienced a significant reduction in weight-bearing pain compared to the hyaluronic acid group after six weeks. However, the other measures of pain and quality of life did not exhibit notable differences between the groups.
Overall, polynucleotide sodium proved more effective in alleviating weight-bearing pain in this limited study.
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Most Useful Reviews
10
Maintaining joint health
37 people found this helpful
Great for LMTs with osteoarthritis. As a massage therapist, I faced joint pain in my right thumb due to improper technique, and feared for my career. In my search, I found hyaluronic acid, though opinions on whether articular cartilage can heal itself vary. I've been taking this for a few weeks, and my thumb now feels normal with no pain. While I continue massaging, I'm also undertaking efforts for a low-inflammation diet and additional treatments. I can't find fault with this product, as it's aiding me during this challenging period.
Read More
10
Knee pain eliminated
6 people found this helpful
This REALLY works. I've been taking this supplement for many years. I genuinely believe it has replaced the cushioning in my knee after two surgeries, resulting in bone on bone issues. I can now run again, pain-free, without needing knee support. Previous glucosamine supplements did not help, but this one certainly does!
Read More
9
Knee pain relief
4 people found this helpful
I can't go without it now! Especially in the cold, I no longer experience knee pain. This product has become essential not only for my joints but also for my hair and skin.
Pilot Study to Evaluate the Efficacy of Polynucleotide Sodium Compared to Sodium Hyaluronate and Crosslinked Sodium Hyaluronate in Patients with Knee Osteoarthritis.
We engaged in a pilot study comparing the effectiveness of polynucleotide sodium with sodium hyaluronate for knee osteoarthritis pain relief. With 15 patients divided into three groups, all received ultrasound-guided injections over three weeks.
Our findings showed that those treated with polynucleotide sodium experienced a significant reduction in weight-bearing pain compared to the hyaluronic acid group after six weeks. However, the other measures of pain and quality of life did not exhibit notable differences between the groups.
Overall, polynucleotide sodium proved more effective in alleviating weight-bearing pain in this limited study.
Read More
User Reviews
USERS' SCORE
Good
Based on 25 Reviews
8.2
All Reviews
Positive Reviews
Negative Reviews
10
Maintaining joint health
37 people found this helpful
Great for LMTs with osteoarthritis. As a massage therapist, I faced joint pain in my right thumb due to improper technique, and feared for my career. In my search, I found hyaluronic acid, though opinions on whether articular cartilage can heal itself vary. I've been taking this for a few weeks, and my thumb now feels normal with no pain. While I continue massaging, I'm also undertaking efforts for a low-inflammation diet and additional treatments. I can't find fault with this product, as it's aiding me during this challenging period.
Read More
10
Knee pain eliminated
6 people found this helpful
This REALLY works. I've been taking this supplement for many years. I genuinely believe it has replaced the cushioning in my knee after two surgeries, resulting in bone on bone issues. I can now run again, pain-free, without needing knee support. Previous glucosamine supplements did not help, but this one certainly does!
Read More
9
Knee pain relief
4 people found this helpful
I can't go without it now! Especially in the cold, I no longer experience knee pain. This product has become essential not only for my joints but also for my hair and skin.
Read More
9
Eliminated joint snapping
2 people found this helpful
This hyaluronic acid by Now brand is VERY good. I'm convinced H A is injected into race horses’ joints to reduce pain. I developed snapping in my right ankle, knee, and hip when walking due to diminished natural lubrication. I began taking one 100 mg tablet daily, then increased to three after two weeks. After about six weeks, the snapping stopped. I continued with that intake for another six months and now take two tablets daily for maintenance. I have not experienced any side effects and highly recommend this product.
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9
Mobility restored
1 people found this helpful
Life-Changing Duo: Hyaluronic Acid and Collagen Supplements! I've had dry skin and joint discomfort for years, but after two weeks of taking these supplements, everything changed! My bone pain has disappeared, allowing me to walk comfortably again. Now, I can enjoy long walks without discomfort. This regimen is straightforward: I take Hyaluronic Acid with meals for hydration and Collagen before bedtime for joint comfort. I'm thrilled with the results and will definitely continue purchasing.
Bone pain is a discomfort or ache that originates within the bones themselves and can range from mild to severe. It is different from muscle or joint pain, as it directly affects the skeletal structure. Bone pain can be caused by a variety of factors, including injuries, medical conditions such as osteoarthritis or osteoporosis, infections, or tumors. Symptoms may vary depending on the underlying cause but often include a dull, penetrating ache that may worsen with movement or pressure.
If you're experiencing persistent bone pain, it’s essential to consult with a healthcare professional for a proper diagnosis and treatment plan. Imaging tests like X-rays, MRI, or CT scans may be utilized to determine the root cause of the pain. Treatment can vary widely, ranging from medications to alleviate pain and inflammation to physical therapy or, in some cases, surgical interventions. Understanding the underlying cause is crucial to effectively managing bone pain and ensuring the best path to recovery.
Hyaluronic acid is a naturally occurring substance in the body, particularly abundant in connective tissues, skin, and eyes. It plays a crucial role in retaining moisture, making it vital for maintaining healthy skin hydration and elasticity. As a humectant, hyaluronic acid can hold up to 1,000 times its weight in water, which is why it's a favored ingredient in many skincare products. When applied topically, it helps to draw moisture into the skin, leaving it plump and well-hydrated.
In addition to its hydrating properties, hyaluronic acid has gained popularity for its potential anti-aging benefits. It helps to diminish the appearance of fine lines and wrinkles by creating a smoother skin texture. Many experts recommend incorporating hyaluronic acid into your skincare routine, particularly if you have dry or dehydrated skin, as it can complement other treatments and products effectively. Overall, hyaluronic acid is an essential component for those seeking to enhance their skin’s moisture levels and achieve a youthful glow.
Based on user reviews, the timeline for experiencing relief from bone pain while taking hyaluronic acid and collagen supplements seems to vary, but many users report positive results within a couple of weeks. For instance, one user noted their bone pain disappeared after just two weeks of taking the supplements Read Review. Another review mentioned a significant reduction in discomfort after 15 days of use Read Review.
Interestingly, some users have stated that they felt improvements in as little as a week of starting the supplements Read Review. Overall, while results may differ based on individual circumstances and the severity of bone pain, it's common for users to see noticeable benefits within the first month of taking these supplements, with sustained use potentially amplifying these results over time Read Review.
The research findings suggest a potential benefit of polynucleotide sodium in alleviating bone pain, specifically in the context of knee osteoarthritis. A pilot study indicated that patients receiving polynucleotide sodium injections experienced a significant reduction in weight-bearing pain when compared to those treated with hyaluronic acid. However, it is important to note that other pain measures and quality of life indicators did not show significant differences between the groups [1].
While these results are promising, they stem from a limited sample size and a specific patient population. Therefore, more extensive research is warranted to substantiate the effectiveness of polynucleotide sodium for bone pain relief across broader demographics and different conditions. As such, while there is preliminary evidence supporting its use, consumers should exercise caution and consult healthcare professionals before considering this treatment option.
Users of hyaluronic acid and collagen supplements have reported a range of improvements in their symptoms, particularly concerning joint pain and skin hydration. Many participants indicate that they experienced significant reductions in joint discomfort within a short period. For example, one user noted their knee pain completely vanished after just two weeks of use Read Review. Another user remarked on a remarkable 60-70% reduction in bone pain and was able to stop taking painkillers just a week into their regimen Read Review.
In addition to pain relief, several users have highlighted the products' benefits for skin quality. Increased skin elasticity and hydration were common themes in reviews, with one user sharing that their skin after a month showed noticeable improvement, particularly around the eyes Read Review. While many users report substantial benefits, individual results may vary, with a few noting little to no effect despite continued use Read Review. Overall, many reviewers express satisfaction with their experience, praising the dual benefits for both joints and skin.
Users have reported positive experiences when combining hyaluronic acid with collagen and other supplements to alleviate bone pain. Many individuals have noted significant improvements in their symptoms after integrating these supplements into their daily regimen. For instance, one user experienced a 60-70% reduction in bone pain and was able to stop taking painkillers just a week into their combination use of hyaluronic acid and collagen Read Review. Another reviewer mentioned a notable alleviation of knee pain after two weeks of using both supplements together, leading to a comfortable walking experience for the first time in years Read Review.
Some users reported mixed results, with a few indicating that despite combining hyaluronic acid with other supplements, their bone pain did not improve significantly Read Review. However, on the whole, the majority of feedback suggests that users found this combination beneficial for joint support and pain relief, corroborating the idea that these supplements work synergistically to enhance overall joint health Read Review. Users who also incorporated items like glucosamine noted reduced inflammation and increased mobility, showing that the right combinations could lead to impactful results in managing bone pain.
Users report positive experiences with various doses of Hyaluronic Acid for alleviating bone pain, emphasizing a range of consumption patterns. Many reviewers found significant relief while taking between 1 to 3 capsules daily, often in conjunction with collagen for enhanced effects. For example, one user noted a marked improvement in knee pain after consistently taking 100mg, reporting complete resolution of joint pain Read Review. Another individual mentioned substantial pain reduction—approximately 60-70%—after a month of combined use with collagen Read Review.
Additionally, users shared a gradient of experiences based on the duration of consumption. One reviewer observed significant joint pain relief within just two weeks of taking two pills daily Read Review, while another mentioned achieving comfort after one month of treatment with two capsules a day Read Review. This suggests that while higher doses may enhance effectiveness, individual responses can vary widely, indicating the importance of personalizing dosage.
9
Mobility restored
1 people found this helpful
Life-Changing Duo: Hyaluronic Acid and Collagen Supplements! I've had dry skin and joint discomfort for years, but after two weeks of taking these supplements, everything changed! My bone pain has disappeared, allowing me to walk comfortably again. Now, I can enjoy long walks without discomfort. This regimen is straightforward: I take Hyaluronic Acid with meals for hydration and Collagen before bedtime for joint comfort. I'm thrilled with the results and will definitely continue purchasing.
9
Relief for knees
1 people found this helpful
Bought for my husband who, after 15 days, feels the benefits on his osteoarthritis pain in his knees. He is much more relieved and in less pain than before taking this supplement. I'm going to buy some for my mum to help relieve her where the osteoarthritis is more advanced.
9
Relief from bone pain
1 people found this helpful
I bought a gilauron for my husband for his bones, as he had an issue with the meniscus. He felt relief after just a week.
9
Significant reduction
1 people found this helpful
I have been using this product for a month now alongside collagen, and it reduced my bone pain by 60-70%. I stopped the painkillers after about a week of using it, and I am very pleased with the outcome.
9
Knee pain relief
4 people found this helpful
I can't go without it now! Especially in the cold, I no longer experience knee pain. This product has become essential not only for my joints but also for my hair and skin.
7.5
Improved joint health
Excellent for skin and joints! I have noticed much improvement in my skin, especially around my eyes, and my joints are much less sore. Hyaluronic acid is great for skin health, joint lubrication, and relieving bone pain. All this in a small, easy-to-swallow capsule. I am definitely sold on this product!
0
No improvement noted
It has no effect. Despite taking it alongside other supplements, my bone pain has not improved.
7.5
Improved joint pain
This hyaluronic acid product is of good quality and reasonably priced. At 67 years old, I've noticed a considerable improvement in my joint pain since taking it.
9
Joint pain eradicated
1 people found this helpful
Excellent! This 100mg dose has resolved my joint pain completely.
10
Discomfort vanished
After injuring my knee during a fitness class, I took two pills daily for two weeks, and all discomfort has completely disappeared. I plan to continue taking them.
9
Knee pain relief
I liked the result after taking collagen types 1 and 3 along with hyaluronic acid. I took 2 capsules for two months to relieve aching pain in my knees. After about a month, I felt relief, and then the bone pain stopped entirely. Now, after a year, I plan to repeat the course for 2 to 3 months.
8
Polynucleotide sodium reduces knee pain
Pilot Study to Evaluate the Efficacy of Polynucleotide Sodium Compared to Sodium Hyaluronate and Crosslinked Sodium Hyaluronate in Patients with Knee Osteoarthritis.
We engaged in a pilot study comparing the effectiveness of polynucleotide sodium with sodium hyaluronate for knee osteoarthritis pain relief. With 15 patients divided into three groups, all received ultrasound-guided injections over three weeks.
Our findings showed that those treated with polynucleotide sodium experienced a significant reduction in weight-bearing pain compared to the hyaluronic acid group after six weeks. However, the other measures of pain and quality of life did not exhibit notable differences between the groups.
Overall, polynucleotide sodium proved more effective in alleviating weight-bearing pain in this limited study.
References
Kim JY, Kim YN, Lee YJ, Sim SE, Ko YR, et al. Pilot Study to Evaluate the Efficacy of Polynucleotide Sodium Compared to Sodium Hyaluronate and Crosslinked Sodium Hyaluronate in Patients with Knee Osteoarthritis. J Clin Med. 2021;10. doi:10.3390/jcm10051138