Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.4
USERS' SCORE
Good
Based on 8 Reviews
8.1
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Sodium (from Sodium Hyaluronate)
10 mg
< 1 %
Hyaluronic Acid (from Sodium Hyaluronate)
100 mg
L-Proline (Free-Form)
100 mg
Alpha Lipoic Acid
50 mg
Grape Seed Extract (Vitis vinifera)(Standardized for Polyphenols)
25 mg

Top Medical Research Studies

9
Hyaluronic acid gel shows promise
We examined the effects of a gel containing hyaluronic acid on women experiencing vaginal atrophy symptoms after menopause. The pilot and multicenter studies involved 110 postmenopausal participants using the gel both externally and vaginally. Results showed significant improvements in vaginal dryness, burning, itching, and rash from the first week of treatment, without any reported adverse effects. Overall, the gel was well-accepted and demonstrated promise as a safe alternative to traditional hormone replacement therapies.
Read More
8
Hyaluronic acid enhances skin regeneration
This study investigated how hyaluronic acid (HA) enhances the effects of transfersomal serum containing amniotic mesenchymal stem cells metabolite products on skin regeneration.

We found that adding HA significantly improved skin hydration, collagen density, and fibroblast cell numbers in UV-induced aged mice. Encouragingly, there were no reports of skin rash or irritation after topical application.

This shows that the combination of HA and AMSC-MP can effectively support skin health without causing adverse effects.
Read More
8
COVID-19 exacerbates dermatitis herpetiformis
We observed a compelling case where a 74-year-old woman experienced a severe flare of dermatitis herpetiformis, a rare autoimmune skin condition, following a COVID-19 infection.

Initially, she presented with blisters and oral ulcers. After treatment that included hyaluronic acid mouthwash, her oral lesions showed remarkable improvement over four weeks.

Unfortunately, after contracting COVID-19, she had another flare-up, but again, her symptoms resolved after a month of treatment. This highlights the impact of COVID-19 on existing autoimmune conditions.
Read More

Most Useful Reviews

9
Effective for skin
18 people found this helpful
This product is brilliant! My facial skin improved significantly during usage, with rashes vanishing and joint pain resolving. I alternate between two months of intake and two months of rest. If you found this review helpful, please like it :)
Read More
9
Skin condition improved
1 people found this helpful
Excellent! My facial skin condition improved substantially with no rashes during treatment, and my knee pain disappeared. I follow a cycle of two months on, then two months off. If you found this review helpful, please like it :)
Read More
10
Comprehensive formula
During my intake, my facial skin dramatically improved, and the rashes disappeared, alongside relief from knee pain. Hyaluronic acid is crucial for all body tissues, notably connective tissue. It promotes lubrication in joint fluid and resists compressive forces. The addition of L-Proline, Alpha Lipoic Acid, and Grape Seed Extract enhances the formulation significantly.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.4
  • All Researches
9
Hyaluronic acid gel shows promise
We examined the effects of a gel containing hyaluronic acid on women experiencing vaginal atrophy symptoms after menopause. The pilot and multicenter studies involved 110 postmenopausal participants using the gel both externally and vaginally. Results showed significant improvements in vaginal dryness, burning, itching, and rash from the first week of treatment, without any reported adverse effects. Overall, the gel was well-accepted and demonstrated promise as a safe alternative to traditional hormone replacement therapies.
Read More
9
Effective treatment for atopic dermatitis
We explored the impact of MAS063DP cream on mild to moderate atopic dermatitis in a clinical study involving 218 adults. Patients were randomly assigned to use either the MAS063DP cream or a placebo for 50 days, applying it three times daily to affected skin areas. Our results showed that MAS063DP was significantly more effective in reducing symptoms compared to the vehicle, with lower rates of rash reported in the treatment group. This indicates that MAS063DP cream is a promising option for managing atopic dermatitis.
Read More
8
Hyaluronic acid enhances skin regeneration
This study investigated how hyaluronic acid (HA) enhances the effects of transfersomal serum containing amniotic mesenchymal stem cells metabolite products on skin regeneration.

We found that adding HA significantly improved skin hydration, collagen density, and fibroblast cell numbers in UV-induced aged mice. Encouragingly, there were no reports of skin rash or irritation after topical application.

This shows that the combination of HA and AMSC-MP can effectively support skin health without causing adverse effects.
Read More
8
COVID-19 exacerbates dermatitis herpetiformis
We observed a compelling case where a 74-year-old woman experienced a severe flare of dermatitis herpetiformis, a rare autoimmune skin condition, following a COVID-19 infection.

Initially, she presented with blisters and oral ulcers. After treatment that included hyaluronic acid mouthwash, her oral lesions showed remarkable improvement over four weeks.

Unfortunately, after contracting COVID-19, she had another flare-up, but again, her symptoms resolved after a month of treatment. This highlights the impact of COVID-19 on existing autoimmune conditions.
Read More
8
Hyaluronic acid treatments reduce wrinkles
We explored the effectiveness of two hyaluronic acid fillers in treating superficial wrinkles around the mouth. In a double-blind study involving 48 patients, we compared small-particle hyaluronic acid with lidocaine to cohesive polydensified matrix hyaluronic acid.

Both treatments reduced wrinkling, with notable results maintained for 180 days. However, the small-particle approach showed superior effectiveness as rated by both patients and investigators after the treatment period. While both products had similar safety profiles, adverse reactions included some rash among patients using cohesive matrix fillers.
Read More

User Reviews

USERS' SCORE
Good
Based on 8 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Effective for skin
18 people found this helpful
This product is brilliant! My facial skin improved significantly during usage, with rashes vanishing and joint pain resolving. I alternate between two months of intake and two months of rest. If you found this review helpful, please like it :)
Read More
9
Skin condition improved
1 people found this helpful
Excellent! My facial skin condition improved substantially with no rashes during treatment, and my knee pain disappeared. I follow a cycle of two months on, then two months off. If you found this review helpful, please like it :)
Read More
10
Comprehensive formula
During my intake, my facial skin dramatically improved, and the rashes disappeared, alongside relief from knee pain. Hyaluronic acid is crucial for all body tissues, notably connective tissue. It promotes lubrication in joint fluid and resists compressive forces. The addition of L-Proline, Alpha Lipoic Acid, and Grape Seed Extract enhances the formulation significantly.
Read More
9
Happy skin experience
I'm thrilled! My hair ceased showing, my skin improved with no rashes, and I couldn’t be happier. I took it for my joints, and unexpectedly, new hair started growing. I highly recommend it!
Read More
7.5
Significant skin improvement
19 people found this helpful
Over seven years of struggling with atopic dermatitis post-pregnancy, I experienced numerous exacerbations with no lasting relief despite various treatments. I discovered an article by a doctor who personally dealt with arterial blood pressure issues and researched German studies. Following her advice, I took Hyaluronic acid, collagen, and wheat phytoceramides. The outcome has been remarkable; after such a long time, my red spots have diminished to minor rashes on my arms and neck. I'm overjoyed and hope this information helps others - please consult your doctor!
Read More

Frequently Asked Questions

7.5
Fresh face result
8 people found this helpful
I combined hyaluronic acid with collagen and vitamin C. After a month, my face appears fresher, with fewer rashes and reduced fine wrinkles at age 37. The capsules are quite large and have a snap-on lid that's more convenient for me than a screw-on one. I chose Hyaluronic Acid based on reviews and ratings!
9
Effective for skin
18 people found this helpful
This product is brilliant! My facial skin improved significantly during usage, with rashes vanishing and joint pain resolving. I alternate between two months of intake and two months of rest. If you found this review helpful, please like it :)
9
Skin condition improved
1 people found this helpful
Excellent! My facial skin condition improved substantially with no rashes during treatment, and my knee pain disappeared. I follow a cycle of two months on, then two months off. If you found this review helpful, please like it :)
10
Comprehensive formula
During my intake, my facial skin dramatically improved, and the rashes disappeared, alongside relief from knee pain. Hyaluronic acid is crucial for all body tissues, notably connective tissue. It promotes lubrication in joint fluid and resists compressive forces. The addition of L-Proline, Alpha Lipoic Acid, and Grape Seed Extract enhances the formulation significantly.
9
Happy skin experience
I'm thrilled! My hair ceased showing, my skin improved with no rashes, and I couldn’t be happier. I took it for my joints, and unexpectedly, new hair started growing. I highly recommend it!
7.5
Significant skin improvement
19 people found this helpful
Over seven years of struggling with atopic dermatitis post-pregnancy, I experienced numerous exacerbations with no lasting relief despite various treatments. I discovered an article by a doctor who personally dealt with arterial blood pressure issues and researched German studies. Following her advice, I took Hyaluronic acid, collagen, and wheat phytoceramides. The outcome has been remarkable; after such a long time, my red spots have diminished to minor rashes on my arms and neck. I'm overjoyed and hope this information helps others - please consult your doctor!
2
Allergy caution
1 people found this helpful
I ordered hyaluronic acid for moisturising my nose, eyes, and skin. While it performs well, I developed allergies, likely due to grape seed in the ingredients (which causes a rash for me). I split the capsule to avoid discomfort. I wouldn't recommend taking it without a capsule as the contents can irritate and cause heartburn.
1
Skin rashes occurred
I recognise this is vital for women’s health and youth, but it caused rashes on my back. I haven’t stopped taking it yet, so let's see what happens next.
8
Hyaluronic acid enhances skin regeneration
This study investigated how hyaluronic acid (HA) enhances the effects of transfersomal serum containing amniotic mesenchymal stem cells metabolite products on skin regeneration.

We found that adding HA significantly improved skin hydration, collagen density, and fibroblast cell numbers in UV-induced aged mice. Encouragingly, there were no reports of skin rash or irritation after topical application.

This shows that the combination of HA and AMSC-MP can effectively support skin health without causing adverse effects.
9
Hyaluronic acid gel shows promise
We examined the effects of a gel containing hyaluronic acid on women experiencing vaginal atrophy symptoms after menopause. The pilot and multicenter studies involved 110 postmenopausal participants using the gel both externally and vaginally. Results showed significant improvements in vaginal dryness, burning, itching, and rash from the first week of treatment, without any reported adverse effects. Overall, the gel was well-accepted and demonstrated promise as a safe alternative to traditional hormone replacement therapies.
9
Effective treatment for atopic dermatitis
We explored the impact of MAS063DP cream on mild to moderate atopic dermatitis in a clinical study involving 218 adults. Patients were randomly assigned to use either the MAS063DP cream or a placebo for 50 days, applying it three times daily to affected skin areas. Our results showed that MAS063DP was significantly more effective in reducing symptoms compared to the vehicle, with lower rates of rash reported in the treatment group. This indicates that MAS063DP cream is a promising option for managing atopic dermatitis.

References

  1. Miatmoko A, Dewangga SS, Handoko KK, Legowo D, Purwantari KE, et al. Transfersomal serum loading amniotic mesenchymal stem cells metabolite products with hyaluronic acid addition for skin regeneration in UV aging-induced mice. Int J Pharm. 2024;667:124950. doi:10.1016/j.ijpharm.2024.124950
  2. Shafuria A, Sufiawati I, Usman HA. A Rare Case of COVID-19-Induced Acute Exacerbation of Oral Dermatitis Herpetiformis in a Geriatric Patient. Int Med Case Rep J. 2023;16:129. doi:10.2147/IMCRJ.S401775
  3. Polacco MA, Singleton AE, Luu T, Maas CS. A Randomized, Blinded, Prospective Clinical Study Comparing Small-Particle Versus Cohesive Polydensified Matrix Hyaluronic Acid Fillers for the Treatment of Perioral Rhytids. Aesthet Surg J. 2021;41:NP493. doi:10.1093/asj/sjaa161
  4. Morali G, Polatti F, Metelitsa EN, Mascarucci P, Magnani P, et al. Open, non-controlled clinical studies to assess the efficacy and safety of a medical device in form of gel topically and intravaginally used in postmenopausal women with genital atrophy. Arzneimittelforschung. 2006;56:230.
  5. Abramovits W, Boguniewicz M. A multicenter, randomized, vehicle-controlled clinical study to examine the efficacy and safety of MAS063DP (Atopiclair) in the management of mild to moderate atopic dermatitis in adults. J Drugs Dermatol. 2006;5:236.
image