Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Moderately Good
Based on 24 Reviews
7.8
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
L-Lysine (from 637 mg L-Lysine Hydrochloride)
500 mg
**

Top Medical Research Studies

9
RCI001 shows promise for Sjögren syndrome
We investigated how RCI001 can help mice with primary Sjögren syndrome. Eight 12-week-old NOD.B10-H2b mice were divided into two groups, one receiving RCI001 and the other a control treatment.

After one week, we noted significant improvements in eye health and tear secretion for the RCI group. They also showed reduced levels of inflammatory markers compared to those treated with the control. Overall, RCI001 proved to effectively reduce inflammation and oxidative stress, suggesting a promising therapeutic option for this autoimmune disease.
Read More
We delved into the potential of plant-derived cyclotides, particularly focusing on a modified version of kalata B1, known as [T20K], for autoimmune disorders such as multiple sclerosis. Our investigations revealed that daily doses in mice led to reduced cytokine levels and minimal inflammation, suggesting a promising alternative to traditional immunosuppressive drugs. While the results are encouraging, further research is needed to fully assess the effectiveness of cyclotides in human applications. Overall, cyclotides appear to hold significant promise in the realm of immune modulation.
Read More

Most Useful Reviews

9
Autism support
43 people found this helpful
I’ve started giving L-lysine to my daughter, noticing improvements with her autism-related symptoms. While some herpes lesions initially appeared, as they cleared, her cognitive function seemed to improve. It appears that lysine plays an essential role here.
Read More
9
Herpes symptom relief
6 people found this helpful
I give L-lysine to my son, and it has significantly reduced his herpes outbreaks. Increasing to two tablets daily proved effective; symptoms clear up much faster now—previously, they lasted weeks.
Read More
7.5
Herpes recurrence prevention
6 people found this helpful
L-lysine is beneficial for preventing herpes recurrences and boosting immunity, especially when paired with other vitamins. After a year of intermittent use, my husband's outbreaks have considerably decreased, making it invaluable for our health.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
  • All Researches
9
RCI001 shows promise for Sjögren syndrome
We investigated how RCI001 can help mice with primary Sjögren syndrome. Eight 12-week-old NOD.B10-H2b mice were divided into two groups, one receiving RCI001 and the other a control treatment.

After one week, we noted significant improvements in eye health and tear secretion for the RCI group. They also showed reduced levels of inflammatory markers compared to those treated with the control. Overall, RCI001 proved to effectively reduce inflammation and oxidative stress, suggesting a promising therapeutic option for this autoimmune disease.
Read More
We delved into the potential of plant-derived cyclotides, particularly focusing on a modified version of kalata B1, known as [T20K], for autoimmune disorders such as multiple sclerosis. Our investigations revealed that daily doses in mice led to reduced cytokine levels and minimal inflammation, suggesting a promising alternative to traditional immunosuppressive drugs. While the results are encouraging, further research is needed to fully assess the effectiveness of cyclotides in human applications. Overall, cyclotides appear to hold significant promise in the realm of immune modulation.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 24 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Autism support
43 people found this helpful
I’ve started giving L-lysine to my daughter, noticing improvements with her autism-related symptoms. While some herpes lesions initially appeared, as they cleared, her cognitive function seemed to improve. It appears that lysine plays an essential role here.
Read More
9
Herpes symptom relief
6 people found this helpful
I give L-lysine to my son, and it has significantly reduced his herpes outbreaks. Increasing to two tablets daily proved effective; symptoms clear up much faster now—previously, they lasted weeks.
Read More
7.5
Herpes recurrence prevention
6 people found this helpful
L-lysine is beneficial for preventing herpes recurrences and boosting immunity, especially when paired with other vitamins. After a year of intermittent use, my husband's outbreaks have considerably decreased, making it invaluable for our health.
Read More
9
Cold sore prevention
5 people found this helpful
This product has significantly strengthened my immune system and is effective against the onset of colds and herpes. I recommend it for family use during preventive measures.
Read More
9
Rapid healing benefits
5 people found this helpful
After contracting COVID, I experienced herpes outbreaks. Taking 8g of lysine per day cleared the rashes very quickly. It was effective within days, contributing to my overall recovery.
Read More

Frequently Asked Questions

7.5
Positive changes noted
5 people found this helpful
I purchased L-lysine for my husband as part of his autoimmune disorder treatment. After three weeks, we observed positive changes, such as reduced joint inflammation and clearer skin. While the autoimmune disorder cannot be cured, it can enter remission with proper nutrition and dietary supplements. I appreciate the quality and ingredients from this company.
7.5
Effective supplement
5 people found this helpful
I find this company's lysine exceptional, enjoying its forms and dosages. Drinking 1 gram in two tablets before meals is more comfortable than swallowing large pills. Lysine truly works for me and my loved ones, serving as an excellent preventative measure and helping accelerate remission during autoimmune disorder flare-ups. If I could only recommend one product from iHerb, it would be lysine. The tablets are a perfect size with no taste, and the benefits are clear. The packaging is standard for dietary supplements.
6
Herpes management
148 people found this helpful
A fantastic product for an amazing price! After trying various medications for herpes with no success, I opted for Lysine. It has significantly improved my condition, and I'm advised to continue for six months for the best results.
9
Herpes occurrences reduced
3 people found this helpful
After two years, I'm finally writing a review. Previously, herpes plagued me, showing up almost daily. A course of acyclovir failed to help, so I decided to try lysine. Since taking it, I've experienced far fewer outbreaks. This supplement has truly made a difference in managing my herpes symptoms.
7.5
Rapid recovery observed
1 people found this helpful
My husband suffers from herpes on his lips, and I ordered this product for him during an outbreak. His symptoms passed much quicker than usual, with discomfort like bloating and tingling disappearing within 24 hours. It's an excellent tool for managing his condition!
9
Supports immune system
I ordered L-Lysine after learning its role in tissue healing and the immune system. After several months, I noticed my wounds heal much faster and it supports me during seasonal colds. I highly recommend it for anyone wanting to enhance their immune system.
7.5
Herpes recurrence prevention
6 people found this helpful
L-lysine is beneficial for preventing herpes recurrences and boosting immunity, especially when paired with other vitamins. After a year of intermittent use, my husband's outbreaks have considerably decreased, making it invaluable for our health.
9
Faster healing noted
2 people found this helpful
I ordered this amino acid for my son, who frequently suffers from herpes. During flare-ups, he took one capsule three times daily, which significantly sped up his recovery. If you're hesitant about trying it, I wholeheartedly recommend it; it's a working supplement!
9
Rapid healing benefits
5 people found this helpful
After contracting COVID, I experienced herpes outbreaks. Taking 8g of lysine per day cleared the rashes very quickly. It was effective within days, contributing to my overall recovery.
9
Consistent effectiveness
1 people found this helpful
Herpes outbreaks were a frequent issue for me, but I've noticed a significant decrease since I began taking lysine. I typically take one tablet on an empty stomach each morning, and when I feel an outbreak approaching, I take two. The 500mg pills are easy to swallow, and I find them effective. I'll continue to use lysine as long as herpes is a concern for me.
9
Miraculous recovery
5 people found this helpful
I recovered quickly from COVID symptoms after taking lysine, and when a herpes outbreak appeared, doubling my dosage led to astonishing results—almost immediate healing. I'll be keeping this on hand continuously from now on.
We delved into the potential of plant-derived cyclotides, particularly focusing on a modified version of kalata B1, known as [T20K], for autoimmune disorders such as multiple sclerosis. Our investigations revealed that daily doses in mice led to reduced cytokine levels and minimal inflammation, suggesting a promising alternative to traditional immunosuppressive drugs. While the results are encouraging, further research is needed to fully assess the effectiveness of cyclotides in human applications. Overall, cyclotides appear to hold significant promise in the realm of immune modulation.
9
RCI001 shows promise for Sjögren syndrome
We investigated how RCI001 can help mice with primary Sjögren syndrome. Eight 12-week-old NOD.B10-H2b mice were divided into two groups, one receiving RCI001 and the other a control treatment.

After one week, we noted significant improvements in eye health and tear secretion for the RCI group. They also showed reduced levels of inflammatory markers compared to those treated with the control. Overall, RCI001 proved to effectively reduce inflammation and oxidative stress, suggesting a promising therapeutic option for this autoimmune disease.

References

  1. Mishra R, Agarwal P, Sharma A, Mittal M, Gulati P, et al. Plant-derived Cyclotides in Immunomodulation and their Therapeutic Potential. Protein Pept Lett. 2025. doi:10.2174/0109298665364479250214101422
  2. Kang H, Jung YH, Moon J, Ryu JS, Yoon CH, et al. Efficacy of RCI001 as a Therapeutic Candidate in a Primary Sjögren Syndrome Mouse Model. Cornea. 2025;44:226. doi:10.1097/ICO.0000000000003696
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