5/27/2025
Last update
5/27/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Good
Based on 75 Reviews
8.3
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Magnesium (elemental) (from Magnesium Oxide, Magnesium Citrate and Magnesium Aspartate)
400 mg
95%
Top Medical Research Studies
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
7
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More
Most Useful Reviews
9
Muscle pain relief
230 people found this helpful
Good magnesium; I take it regularly. My muscle pain has disappeared.
Read More
9
Effective for pain
201 people found this helpful
Magnesium has perfectly helped me manage muscle pain; this new brand has proven reliable.
Read More
9
Supports bone health
177 people found this helpful
Excellent! Magnesium is a vital mineral for everyone. It aids in the metabolism, calcium absorption, and is essential for bone and muscle health. This product offers magnesium in three forms, providing a convenient daily dosage with a significant number of capsules, translating into excellent value. A verified manufacturer ensures peace of mind for users.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
- All Researches
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More
7
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
User Reviews
USERS' SCORE
Good
Based on 75 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Muscle pain relief
230 people found this helpful
Good magnesium; I take it regularly. My muscle pain has disappeared.
Read More
9
Effective for pain
201 people found this helpful
Magnesium has perfectly helped me manage muscle pain; this new brand has proven reliable.
Read More
9
Supports bone health
177 people found this helpful
Excellent! Magnesium is a vital mineral for everyone. It aids in the metabolism, calcium absorption, and is essential for bone and muscle health. This product offers magnesium in three forms, providing a convenient daily dosage with a significant number of capsules, translating into excellent value. A verified manufacturer ensures peace of mind for users.
Read More
9
Quick relief
139 people found this helpful
The effects were noticeable from the first capsule! I take magnesium regularly for my neurological condition; it relaxes my spasticity and aids sleep, particularly in the evening. It also alleviated abdominal pains. I’m very pleased and plan to order more.
Read More
9
Relieves back pain
15 people found this helpful
I bought this magnesium at the request of my father, who has been enduring back pain for years. After just a week, he said he could finally sleep without pain. I’m grateful for the relief it has provided him.
Read More
Frequently Asked Questions
9
Relieves back pain
15 people found this helpful
I bought this magnesium at the request of my father, who has been enduring back pain for years. After just a week, he said he could finally sleep without pain. I’m grateful for the relief it has provided him.
9
Relieves back pain
2 people found this helpful
Until I turned 28, I never took magnesium. However, I began suffering from severe lower back pain that yoga couldn't alleviate. It was suggested by my endocrinologist, and after two weeks of magnesium, the pain disappeared. I continue to use it regularly and recommend it for those experiencing insomnia or high stress.
9
Quick relief
139 people found this helpful
The effects were noticeable from the first capsule! I take magnesium regularly for my neurological condition; it relaxes my spasticity and aids sleep, particularly in the evening. It also alleviated abdominal pains. I’m very pleased and plan to order more.
9
Muscle pain relief
230 people found this helpful
Good magnesium; I take it regularly. My muscle pain has disappeared.
9
Effective against spasms
2 people found this helpful
I started taking this on my neurologist's recommendation for muscle cramps. The effect is noticeable; the pain has subsided, and I highly recommend it!
9
Improves sleep quality
1 people found this helpful
Excellent! Magnesium has substantially helped me overcome sleep issues, muscle pain, and fatigue. After almost two weeks of taking these capsules, I finally sleep soundly, free from muscle discomfort, and feel rejuvenated overall. Good quality and affordable packaging too!
9
Calms convulsions
1 people found this helpful
I ordered this magnesium for my in-laws, who have suffered from convulsions and insomnia. After two months, they were calmer, enjoying sound sleep as cramps and muscle pains disappeared. They take one tablet at night, and it has proven to be very effective.
10
Joint pain miracle
4 people found this helpful
Magnesium is crucial for the nervous and cardiovascular systems. My aunt's osteoarthritis pain disappeared after she began taking it daily. I highly recommend this miracle supplement!
9
Relieved spinal pain
6 people found this helpful
This magnesium supplement helped immensely with the pain of my herniated disc. One capsule meets my daily requirement, and I'm grateful for Iherb's speedy delivery!
7.5
Joint improvement
4 people found this helpful
Excellent for bone health; I feel my joints have improved significantly, alongside noticeable benefits for my nerves. I used it along with zinc and vitamin D, enhancing the overall effects.
9
Supports bone health
177 people found this helpful
Excellent! Magnesium is a vital mineral for everyone. It aids in the metabolism, calcium absorption, and is essential for bone and muscle health. This product offers magnesium in three forms, providing a convenient daily dosage with a significant number of capsules, translating into excellent value. A verified manufacturer ensures peace of mind for users.
10
Back pain relief
5 people found this helpful
My low back pain has vanished! My daughter suggested adding magnesium to balance the calcium I was taking. I am now completely without low back pain. Thank you, iHerb!!!
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
References
- Alsaikhan F, Mahmoud MZ, Suliman M. Synthesis and characterization of novel denosumab/magnesium-based metal organic frameworks nanocomposite prepared by ultrasonic route as drug delivery system for the treatment of osteoporosis. Front Bioeng Biotechnol. 2023;11:1153969. 10.3389/fbioe.2023.1153969
- Jakubowska-Pietkiewicz E, Chlebna-Sokół D. New trends in the treatment of osteogenesis imperfecta type III - own experience. Ortop Traumatol Rehabil. 2008;10:593.
- Johnson JR, Miller AJ. The efficacy of choline magnesium trisalicylate (CMT) in the management of metastatic bone pain: a pilot study. Palliat Med. 1994;8:129.
