We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
Read More
9
Magnesium reduces mortality in HFpEF
Propensity score matched cohort study on magnesium supplementation and mortality in critically ill patients with HFpEF.
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
8
Magnesium levels and heart disease mortality
Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5.
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
Read More
Most Useful Reviews
7.5
Stabilised heart
546 people found this helpful
I consider these capsules essential for managing my atrial fibrillation because I need magnesium. Having taken this complex for two years, I've noticed my heart works more steadily and no longer goes out of rhythm with the slightest excitement. The capsules are small and easy to take, although my wife prefers to empty the powder into her food. The packaging confirms this is acceptable. I highly recommend this product!
Read More
9
Improves sleep quality
133 people found this helpful
Magnesium is a key trace element that aids heart rate, blood pressure regulation, and improves sleep quality. I find this product offers great value with long-lasting supply. I began taking it to enhance sleep quality and reduce muscle cramps, which seems to be effective. It’s best to consult a doctor before determining needs.
Read More
0
No effect noted
48 people found this helpful
We, four people, tried it and it’s truly disappointing. I usually favour NOW Foods products, having 12 open bottles, but this one is worthless. It had no effect on my heart rate or relaxation. For an effective magnesium supplement, I recommend UltraMag from Source Naturals. This is an honest review shared by all of us in the house.
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
8
Magnesium levels and heart disease mortality
Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5.
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
Read More
8
Magnesium intake impacts heart disease risk
Association of magnesium intake with predicted atherosclerotic lesions and cardiovascular risk in young adults based on PDAY score: a cross-sectional study.
We explored the link between magnesium intake and heart disease risk in young adults, using a comprehensive study of U.S. adults aged 20 to 34. This cross-sectional research analyzed data from the National Health and Nutrition Examination Survey, examining dietary habits and various cardiovascular factors.
Our findings suggest that higher magnesium intake is associated with a lower risk of future cardiovascular issues and non-HDL cholesterol problems. This suggests that including magnesium-rich foods in our diets could promote heart health early in life.
Read More
8
Magnesium and potassium reduce BP
Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length.
We analyzed several clinical trials to examine how magnesium and potassium affect systolic blood pressure (SBP) in healthy individuals. Our findings showed that magnesium significantly reduced SBP, especially at lower doses (up to 360 mg/day) and longer treatment periods of over three months. Potassium also played a role but was effective at higher doses and shorter durations.
However, both supplements showed promise in lowering SBP but did not seem to drastically change heart disease risk directly. Further studies will help confirm our results and refine dosage recommendations for better health outcomes.
Read More
8
Calcium-Magnesium Ratio Predicts Prognosis
Serum calcium-magnesium ratio at admission predicts adverse outcomes in patients with acute coronary syndrome.
We explored how the serum calcium-magnesium ratio impacts outcomes in patients with acute coronary syndrome (ACS) by analyzing data from 1,775 individuals who underwent coronary procedures over five years.
By categorizing patients based on their calcium-magnesium levels at admission, we discovered that a higher calcium-to-magnesium ratio correlated with worse outcomes.
Our findings suggest that monitoring this ratio could help predict the prognosis for those dealing with ACS, emphasizing the importance of maintaining a balanced mineral intake for heart health.
I consider these capsules essential for managing my atrial fibrillation because I need magnesium. Having taken this complex for two years, I've noticed my heart works more steadily and no longer goes out of rhythm with the slightest excitement. The capsules are small and easy to take, although my wife prefers to empty the powder into her food. The packaging confirms this is acceptable. I highly recommend this product!
Read More
9
Improves sleep quality
133 people found this helpful
Magnesium is a key trace element that aids heart rate, blood pressure regulation, and improves sleep quality. I find this product offers great value with long-lasting supply. I began taking it to enhance sleep quality and reduce muscle cramps, which seems to be effective. It’s best to consult a doctor before determining needs.
Read More
0
No effect noted
48 people found this helpful
We, four people, tried it and it’s truly disappointing. I usually favour NOW Foods products, having 12 open bottles, but this one is worthless. It had no effect on my heart rate or relaxation. For an effective magnesium supplement, I recommend UltraMag from Source Naturals. This is an honest review shared by all of us in the house.
Read More
9
Reduces anxiety
10 people found this helpful
I found magnesium to be vital for muscle relaxation and overall well-being, which has significantly reduced my anxiety levels. After noticing improvements in my sleep and calmness over two weeks, I've decided to keep taking it. I believe it’s crucial for optimal vitamin absorption and has positively affected my digestive health.
Read More
0
Negative reaction experienced
8 people found this helpful
After taking this blend, I developed pericarditis. I suspect the magnesium aspartate is the cause, as it’s known to be an excitatory neurotransmitter. I’ve had a bad reaction, raising my concern about its connection to heart disease. This isn't an isolated issue, and I hope this review aids others affected.
Heart disease refers to a range of conditions that affect the heart's function and overall health. This umbrella term includes various cardiovascular issues such as coronary artery disease, which is caused by the buildup of plaque in the arteries; heart rhythm problems (arrhythmias); and heart defects present at birth (congenital heart defects). Additionally, heart disease encompasses conditions related to the heart muscle, such as cardiomyopathy, and the heart's valves, which might not open or close properly. The effects of heart disease can be significant, impacting not only physical health but also quality of life, making prevention and timely medical intervention crucial.
Several risk factors contribute to the development of heart disease, including high blood pressure, high cholesterol levels, diabetes, obesity, poor diet, physical inactivity, and smoking. Genetics also play a role, as heart disease can run in families. To mitigate the risks, healthcare professionals typically recommend lifestyle changes such as adopting a heart-healthy diet, engaging in regular physical activity, and avoiding tobacco use. For those already diagnosed with heart disease, treatment options can vary widely, ranging from lifestyle modifications to medications and, in severe cases, surgical interventions. Understanding the nature of heart disease and its risk factors is an essential step toward prevention and effective management.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium is an essential mineral that plays a critical role in cardiovascular health. Research suggests that adequate magnesium intake may help reduce the risk of heart disease by maintaining normal heart rhythm, regulating blood pressure, and supporting overall vascular health. Some studies have shown that higher magnesium levels are associated with lower rates of heart attack and stroke, indicating that this mineral might have a protective effect on the heart. Additionally, magnesium helps with the transport of potassium and calcium, both of which are vital for proper heart function.
However, while magnesium supplementation may benefit those who are deficient, it is important to note that it should not be seen as a standalone treatment for heart disease. Individuals with existing heart conditions should consult their healthcare providers before making any changes to their diet or supplementation regimen. Overall, maintaining a balanced diet rich in magnesium through food sources like leafy greens, nuts, seeds, and whole grains, combined with regular physical activity, may contribute to better heart health.
Based on user reviews, the timeline for experiencing results from magnesium supplements can vary significantly. Some users report noticing improvements in their heart health and overall well-being within a couple of weeks. For instance, one user mentioned seeing enhancements in sleep quality and reductions in anxiety after two weeks of consistent use Read Review. Another user, who has been taking magnesium for two years, claims it has stabilized their heart rhythm considerably Read Review.
On the other hand, some users have had negative experiences, reporting adverse effects almost immediately Read Review. Therefore, while many users see benefits relatively quickly, the results can vary widely, with some experiencing no positive effects at all. It's essential to consult with a healthcare professional to determine the right approach for your specific needs.
The scientific evidence increasingly supports the idea that magnesium supplements may have a beneficial role in heart health, particularly concerning heart disease. For instance, a study involving over 94,000 veterans indicated that those taking magnesium supplements had a lower risk of developing heart failure compared to nonusers, with 8.0% of the supplement users versus 9.7% of nonusers experiencing heart failure [1]. Similarly, another study showed that higher serum magnesium levels were associated with reduced mortality from heart-related conditions among patients with chronic kidney disease, suggesting a potential protective effect of magnesium on cardiovascular health [2].
Furthermore, various studies indicate that magnesium may help improve blood sugar management in individuals with coronary artery disease, which is crucial for heart health [3]. Even in heart failure patients, magnesium supplementation was linked to a significant reduction in early mortality rates [4]. However, it is essential to note that while these findings are promising, there is a call for further research to thoroughly understand the implications and establish optimal usage [1]. Overall, incorporating magnesium through dietary sources or supplements appears to be a worthwhile consideration for those looking to support their heart health.
Based on user reviews, many individuals report significant improvements in various symptoms after incorporating magnesium supplements into their daily routine. For example, several users have noticed enhanced heart stability and rhythm, with one user stating that after two years of use, their heart works more steadily and does not go out of rhythm during excitement Read Review. Others have highlighted improvements in sleep quality and reductions in muscle cramps and anxiety, with one user experiencing a notable decrease in anxiety levels both in terms of sleep and overall calmness Read Review.
However, it is essential to note that individual experiences vary widely. While many users report benefits such as decreased heart palpitations and improved relaxation and overall well-being, a few have had negative reactions, including digestive issues and arrhythmia Read Review. This divergence underscores the importance of consulting healthcare professionals before beginning supplementation, as the effectiveness and side effects may differ greatly from person to person.
Based on user reviews, many individuals have reported positive experiences when combining magnesium supplements with their routines for managing heart disease. Users emphasized that magnesium aids in regulating heart rate and improving overall heart stability, like one reviewer who mentioned their heart no longer goes out of rhythm after taking it for two years Read Review. Additionally, another user highlighted that magnesium is essential for muscle relaxation, which has brought about significant reductions in anxiety levels and improved sleep quality Read Review.
However, experiences were not uniformly positive. Some users reported adverse effects, including stomachaches and arrhythmia, suggesting that not all individuals may react well to magnesium supplementation Read Review. In fact, one user expressed disappointment, claiming the product was counterproductive for their heart disease symptoms Read Review. This variability reinforces the necessity of consulting a healthcare professional before integrating any supplement into a heart disease management plan, to tailor the approach according to individual health needs.
Based on user reviews, magnesium is often reported as a crucial mineral for managing heart disease, with many users highlighting effective dosages ranging between 200 to 400 mg daily. One user specifically noted that a 400 mg capsule supports heart health while also being a good value Read Review. Another mentioned consistency in taking one capsule at night for heart rhythm maintenance and overall well-being Read Review. Moreover, users seem to agree on consulting healthcare professionals before adjusting dosages, suggesting that individual needs may vary Read Review.
However, it’s important to note that experiences are mixed. Some users reported adverse reactions, including increased heart palpitations and gastrointestinal issues, signaling the necessity of careful monitoring and possibly avoiding certain types of magnesium supplements Read Review. Thus, while many find magnesium to be significantly beneficial for heart health, the right dosage should be tailored to individual health conditions and ideally discussed with a healthcare provider for safety and efficacy Read Review.
9
Reduces anxiety
10 people found this helpful
I found magnesium to be vital for muscle relaxation and overall well-being, which has significantly reduced my anxiety levels. After noticing improvements in my sleep and calmness over two weeks, I've decided to keep taking it. I believe it’s crucial for optimal vitamin absorption and has positively affected my digestive health.
7.5
Stable heart rhythm
256 people found this helpful
I've been using this magnesium complex for two years and found my heart to be more stable, without rhythm issues during excitement. The capsules are small and convenient, though my wife prefers to mix the powder with food. The price on this site is great compared to pharmacies, and the dosage works well for me — just one capsule at night.
0
Adverse effects noted
After taking just one capsule, I experienced arrhythmia despite having a healthy heart. My intracranial pressure increased as well. This product is dreadful and has had adverse effects.
7.5
Stabilised heart
546 people found this helpful
I consider these capsules essential for managing my atrial fibrillation because I need magnesium. Having taken this complex for two years, I've noticed my heart works more steadily and no longer goes out of rhythm with the slightest excitement. The capsules are small and easy to take, although my wife prefers to empty the powder into her food. The packaging confirms this is acceptable. I highly recommend this product!
0
Worsened condition observed
This magnesium product is a waste of money; it has caused stomachaches, heart palpitations, and disrupted my sleep. Other magnesium supplements have been effective in relaxing my muscles and aiding sleep, unlike this one. I’m very disappointed with the results, as it seems counterproductive for anyone dealing with heart disease.
9
Supports heart health
1 people found this helpful
NOW Foods Magnesium Capsules are my go-to for heart, muscle, and nervous system health. Each capsule contains 400 mg of magnesium, which is vital for numerous biological processes, including heart health. The packaging has 180 capsules, sufficient for regular use to maintain health.
9
Improves sleep quality
133 people found this helpful
Magnesium is a key trace element that aids heart rate, blood pressure regulation, and improves sleep quality. I find this product offers great value with long-lasting supply. I began taking it to enhance sleep quality and reduce muscle cramps, which seems to be effective. It’s best to consult a doctor before determining needs.
9
Supports overall health
1 people found this helpful
Magnesium activates and supports the heart muscle and regulates various bodily functions. It's essential for protein assimilation, skeletal formation, muscle function, cell regeneration, and blood clotting. When dieting, a magnesium deficiency can occur, but this supplement has worked perfectly for me. I've noticed reduced irritation since I started taking magnesium.
7
Magnesium supplements lower heart failure risk
Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation.
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
8
Magnesium levels and heart disease mortality
Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5.
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
7
Magnesium improves blood sugar control
Serum magnesium, not calcium, is inversely associated with abnormal HbA1c concentrations in adults with coronary artery disease.
We investigated the effect of magnesium and calcium on blood sugar levels in 11,934 patients with coronary artery disease. Our findings indicated that higher serum magnesium levels and a favorable magnesium to calcium ratio were associated with lower abnormal HbA1c levels, which reflect better blood sugar management. In contrast, calcium showed no significant association with HbA1c levels. Importantly, we found no evidence that inflammation played a role in this relationship. Overall, magnesium might be beneficial for maintaining healthy blood sugar levels in those with heart disease.
9
Magnesium reduces mortality in HFpEF
Propensity score matched cohort study on magnesium supplementation and mortality in critically ill patients with HFpEF.
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
References
Cheng Y, Zullo AR, Yin Y, Shao Y, Liu S, et al. Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation. J Am Heart Assoc. 2025;14:e038870. 10.1161/JAHA.124.038870
Moyano-Peregrin C, Rodelo-Haad C, Martín-Malo A, Muñoz-Castañeda JR, Ojeda R, et al. Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5. Clin Kidney J. 2025;18:sfae390. 10.1093/ckj/sfae390
Dong H, Lu N, Wang J, Hu P. Serum magnesium, not calcium, is inversely associated with abnormal HbA1c concentrations in adults with coronary artery disease. Asia Pac J Clin Nutr. 2025;34:104. 10.6133/apjcn.202502_34(1).0010
Song L, Ying J, Li M, Ying L, Zhao C. Propensity score matched cohort study on magnesium supplementation and mortality in critically ill patients with HFpEF. Sci Rep. 2025;15:1944. 10.1038/s41598-025-85931-1
Sun L, Du J. Magnesium status, serum vitamin D concentration and mortality among congestive heart failure patients: a cohort study from NHANES 2007-2018. Magnes Res. 2024;37:61. 10.1684/mrh.2024.0528
Song Q, Song L, Liu H, Tan H, Yang B, et al. Association of magnesium intake with predicted atherosclerotic lesions and cardiovascular risk in young adults based on PDAY score: a cross-sectional study. BMC Public Health. 2024;24:3232. 10.1186/s12889-024-20785-2
Behers BJ, Behers BM, Stephenson-Moe CA, Vargas IA, Meng Z, et al. Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length. Nutrients. 2024;16. 10.3390/nu16213617
Jiang Y, Luo B, Chen Y, Lu W, Peng Y, et al. Serum calcium-magnesium ratio at admission predicts adverse outcomes in patients with acute coronary syndrome. PLoS One. 2024;19:e0313352. 10.1371/journal.pone.0313352
Wyss C, Gündling PW, Kostev K. Real world effectiveness of Hawthorn special extract WS 1442 in a retrospective cohort study from Germany. Sci Rep. 2024;14:22986. 10.1038/s41598-024-74325-4
Seguchi M, Aytekin A, Xhepa E, Haude M, Wlodarczak A, et al. Vascular response following implantation of the third-generation drug-eluting resorbable coronary magnesium scaffold: an intravascular imaging analysis of the BIOMAG-I first-in-human study. EuroIntervention. 2024;20:e1173. 10.4244/EIJ-D-24-00055
Zhang J, Chen Z, Rao L, He Y. Coronary bioresorbable metallic stents: Advancements and future perspectives. J Cardiol. 2025;85:69. 10.1016/j.jjcc.2024.08.003
Copp KL, Steffen LM, Yi SY, Lutsey PL, Rebholz CM, et al. Magnesium-rich diet score is inversely associated with incident cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study. Eur J Prev Cardiol. 2025;32:386. 10.1093/eurjpc/zwae251
Zhuang J, Zhang Q, Wang H, Su PH, Chen PY. Association between short-term changes in serum magnesium and in-hospital mortality following acute myocardial infarction: a cohort study based on the MIMIC database. Magnes Res. 2024;37:45. 10.1684/mrh.2024.0517
Fruh V, Babalola T, Sears C, Wellenius GA, Webster TF, et al. Dietary Minerals and Incident Cardiovascular Outcomes among Never-Smokers in a Danish Case-Cohort Study. Int J Environ Res Public Health. 2024;21. 10.3390/ijerph21070932
Tao J, Wang J, Peng H, Yuan Y, Lai H, et al. Association between serum phosphate, magnesium, calcium and aortic valve sclerosis: a propensity score-matched case-control study. Acta Cardiol. 2024;79:522. 10.1080/00015385.2024.2379682
Zhang J, Sun D, Guo Y, Tong J, Liu Q, et al. Targeted delivery of black phosphorus nanosheets by ROS responsive complex hydrogel based on angiogenesis and antioxidant promotes myocardial infarction repair. J Nanobiotechnology. 2024;22:433. 10.1186/s12951-024-02685-0