Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8
USERS' SCORE
Good
Based on 20 Reviews
8.4
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Magnesium (elemental) (from Magnesium Oxide, Magnesium Citrate and Magnesium Aspartate)
400 mg
95%

Top Medical Research Studies

9
Magnesium sulfate alleviates postoperative pain
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.

Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.

Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Read More
9
Magnesium aids postoperative pain relief
We explored the role of magnesium in reducing knee pain following total knee arthroplasty (TKA). In a study involving 119 adults, participants received either an adductor canal block with magnesium and bupivacaine or just bupivacaine.

Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Read More
9
Magnesium reduces postoperative knee pain
We evaluated the impact of magnesium sulphate on pain levels for 44 patients undergoing staged bilateral total knee arthroplasty.

In this study, the magnesium group received magnesium sulphate while the control group received isotonic saline during their surgeries.

Our findings showed that those who received magnesium experienced significantly lower pain scores compared to the control group, both after their first and second surgeries.

Importantly, magnesium also helped reduce the need for additional pain relief medications in the days following surgery.
Read More

Most Useful Reviews

9
Pain relief
6 people found this helpful
It didn't run out of magnesium, and it helped alleviate my knee pain significantly. I appreciated that one capsule meets my daily needs. Excellent brand. Thank you, iHerb, for the fast delivery to Rio de Janeiro; it arrived in just 10 days.
Read More
10
No more pain
5 people found this helpful
My low back pain has vanished! After my daughter recommended magnesium to balance the calcium, I am now completely free from low back pain. Thank you, iHerb!
Read More
9
Miracle supplement
4 people found this helpful
Magnesium is essential! It supports the nervous and cardiovascular systems. For those with knee pain, it is miraculous. My aunt, suffering from osteoarthritis, found relief in her knee pain by taking magnesium every day. I highly recommend it!
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8
  • All Researches
9
Magnesium sulfate alleviates postoperative pain
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.

Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.

Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Read More
9
Magnesium aids postoperative pain relief
We explored the role of magnesium in reducing knee pain following total knee arthroplasty (TKA). In a study involving 119 adults, participants received either an adductor canal block with magnesium and bupivacaine or just bupivacaine.

Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Read More
9
Magnesium and bupivacaine effective
We evaluated how effective magnesium, especially when combined with bupivacaine, is for managing knee pain after arthroscopy. Our study looked at data from 78 randomized trials involving 4,425 participants.

It turns out that magnesium with bupivacaine is the top performer in easing pain right after surgery and at the 24-hour mark, outperforming other analgesics like morphine.

However, magnesium alone didn’t show significant pain relief. We found that using this combination does not lead to more side effects, making it a safe choice for recovery.
Read More
9
Magnesium reduces postoperative knee pain
We evaluated the impact of magnesium sulphate on pain levels for 44 patients undergoing staged bilateral total knee arthroplasty.

In this study, the magnesium group received magnesium sulphate while the control group received isotonic saline during their surgeries.

Our findings showed that those who received magnesium experienced significantly lower pain scores compared to the control group, both after their first and second surgeries.

Importantly, magnesium also helped reduce the need for additional pain relief medications in the days following surgery.
Read More
9
Magnesium reduces post-surgery pain
We looked into how magnesium can help ease knee pain after total knee arthroplasty. In a study of 80 patients, those who received an injection of magnesium sulfate and ropivacaine experienced significantly less pain and needed less morphine compared to those who got a saline injection. This approach not only reduced morphine use in the first 48 hours but also allowed patients to regain movement quicker. Overall, our findings suggest that magnesium may be a beneficial part of pain management in knee surgery.
Read More

User Reviews

USERS' SCORE
Good
Based on 20 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Pain relief
6 people found this helpful
It didn't run out of magnesium, and it helped alleviate my knee pain significantly. I appreciated that one capsule meets my daily needs. Excellent brand. Thank you, iHerb, for the fast delivery to Rio de Janeiro; it arrived in just 10 days.
Read More
10
No more pain
5 people found this helpful
My low back pain has vanished! After my daughter recommended magnesium to balance the calcium, I am now completely free from low back pain. Thank you, iHerb!
Read More
9
Miracle supplement
4 people found this helpful
Magnesium is essential! It supports the nervous and cardiovascular systems. For those with knee pain, it is miraculous. My aunt, suffering from osteoarthritis, found relief in her knee pain by taking magnesium every day. I highly recommend it!
Read More
9
Calf pain gone
2 people found this helpful
I often woke up at night with calf muscle pain, but after starting magnesium, the discomfort disappeared, and I've continued taking it since.
Read More
9
Knee pain relief
2 people found this helpful
I can't live without this magnesium; my family uses it too. I had knee pain that stopped me from stepping properly, especially at night. After starting Magnesium Dimalate, my pain vanished within a week. My friend had a similar issue, and it worked for her too. It's invaluable for muscle pain and knee pain.
Read More

Frequently Asked Questions

9
Knee pain relief
2 people found this helpful
I can't live without this magnesium; my family uses it too. I had knee pain that stopped me from stepping properly, especially at night. After starting Magnesium Dimalate, my pain vanished within a week. My friend had a similar issue, and it worked for her too. It's invaluable for muscle pain and knee pain.
7.5
Improved joint pain
2 people found this helpful
After a month of use, I felt a noticeable improvement in my knee pain. Much better now!
9
Back pain reduction
2 people found this helpful
Until I was 28, I hadn't taken magnesium, but then I had severe back pain. Despite doing yoga, it didn’t help. After my endocrinologist suggested magnesium, I was amazed—after two weeks of taking it, the pain disappeared completely! I've continued for two years now. It also aids in insomnia and stress.
10
No more pain
5 people found this helpful
My low back pain has vanished! After my daughter recommended magnesium to balance the calcium, I am now completely free from low back pain. Thank you, iHerb!
7.5
Convenient and effective
5 people found this helpful
I always take this type of magnesium; it is of excellent quality and suits my husband perfectly. It significantly reduces his knee pain, and taking it is easy as the capsules are tasteless—good sleep follows!
4
Reduced leg cramps
I used to wake with leg cramps at night, but since beginning magnesium supplements, their frequency has decreased significantly. I'm grateful I started taking it.
7.5
Chronic pain relief
3 people found this helpful
Taking magnesium with vitamin D3 has improved my chronic knee pain significantly. I’ve reduced the number of painkillers I need. I will continue taking it.
7.5
Joint pain relief
5 people found this helpful
Good magnesium. I take it with vitamin D and K, as D depletes magnesium, leading to knee pain. This magnesium significantly eases my knee pain and headaches and helps with menstrual discomfort. I would highly recommend it.
9
Effective for aches
1 people found this helpful
This product and brand are excellent. After starting magnesium, my back and knee pain faded away. 400mg daily is ideal for adults. Thank you, Us Foods!
9
Eased knee pain
5 people found this helpful
The quality is excellent, and the ingredients are safe. If I take one pill daily, I have no issues sleeping, and my knee pain is manageable. About a week after starting, I felt much better. I recommend taking one pill daily for better results.
8
Magnesium aids post-surgery pain relief
We investigated the impact of magnesium sulphate in pain management for patients after unicompartmental knee arthroplasty (UKA). In a controlled trial, 61 patients received either a modified pain relief cocktail with magnesium or a traditional one.

Results showed that the modified cocktail led to less pain medication use and improved early joint recovery. In other words, magnesium seemed to enhance pain control and recovery without the use of additional drugs.
7
Magnesium aids knee surgery recovery
We investigated how magnesium sulfate influences recovery after knee surgery. In our study, 148 elderly patients undergoing total knee arthroplasty were divided into two groups: one received magnesium sulfate, while the other received a saline solution.

This double-blind setup allowed us to see if magnesium sulfate could enhance recovery quality after surgery. Our findings indicate that magnesium sulfate does help reduce early postoperative pain and improves overall recovery in these patients.

Overall, magnesium sulfate appears beneficial in managing pain during the recovery process.
9
Magnesium aids postoperative pain relief
We explored the role of magnesium in reducing knee pain following total knee arthroplasty (TKA). In a study involving 119 adults, participants received either an adductor canal block with magnesium and bupivacaine or just bupivacaine.

Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
9
Magnesium sulfate alleviates postoperative pain
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.

Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.

Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.

References

  1. Zhu Y, Shen S, Cui L, Wu L, Zhang B. Magnesium sulphate and sodium bicarbonate as additives for periarticular local infiltration analgesia improve pain management after unicompartmental knee arthroplasty: a prospective, double-blind, randomized controlled trial. J Orthop Surg Res. 2024;19:764. 10.1186/s13018-024-05233-6
  2. Xu H, Hao C, Wang X, Du J, Zhang T, et al. Effect of Magnesium Sulfate Infusion on Postoperative Quality of Recovery in Patients Undergoing Total Knee Arthroplasty: A Prospective, Double-Blind, Randomized Controlled Trial. Drug Des Devel Ther. 2024;18:919. 10.2147/DDDT.S444896
  3. Zhao C, Wang L, Chen L, Wang Q, Kang P. Effects of magnesium sulfate on periarticular infiltration analgesia in total knee arthroplasty: a prospective, double-blind, randomized controlled trial. J Orthop Surg Res. 2023;18:301. 10.1186/s13018-023-03790-w
  4. Wang Q, Zhao C, Hu J, Ma T, Yang J, et al. Efficacy of a Modified Cocktail for Periarticular Local Infiltration Analgesia in Total Knee Arthroplasty: A Prospective, Double-Blinded, Randomized Controlled Trial. J Bone Joint Surg Am. 2023;105:354. 10.2106/JBJS.22.00614
  5. Choi JW, Lahori A, Merlo JA, Gill O, Ghoddoussi F, et al. Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Postoperative Pain Relief and Decrease Opioid Consumption: A Prospective Randomized Controlled Trial. Clin J Pain. 2022;38:388. 10.1097/AJP.0000000000001036
  6. He Y, He H, Li X, Lei G, Xie D, et al. Intra-Articular Magnesium Plus Bupivacaine Is the Most Effective and Safe Postoperative Analgesic Option Following Knee Arthroscopy: A Network Meta-analysis. Arthroscopy. 2022;38:2897. 10.1016/j.arthro.2022.03.013
  7. Shi L, Zhu H, Ma J, Shi LL, Gao F, et al. Intra-articular magnesium to alleviate postoperative pain after arthroscopic knee surgery: a meta-analysis of randomized controlled trials. J Orthop Surg Res. 2021;16:111. 10.1186/s13018-021-02264-1
  8. Zhao Z, Zhang X, Peng H, Li W, Liu H, et al. Magnesium Sulfate Combined with a Levobupivacaine Periarticular Cocktail for Analgesia in the Early Postoperative Period after Total Knee Arthroplasty. J Knee Surg. 2021;34:1463. 10.1055/s-0040-1710364
  9. Condello V, Filardo G, Madonna V, Andriolo L, Screpis D, et al. Use of a Biomimetic Scaffold for the Treatment of Osteochondral Lesions in Early Osteoarthritis. Biomed Res Int. 2018;2018:7937089. 10.1155/2018/7937089
  10. Shmagel A, Onizuka N, Langsetmo L, Vo T, Foley R, et al. Low magnesium intake is associated with increased knee pain in subjects with radiographic knee osteoarthritis: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2018;26:651. 10.1016/j.joca.2018.02.002
  11. Shin HJ, Kim EY, Na HS, Kim TK, Kim MH, et al. Magnesium sulphate attenuates acute postoperative pain and increased pain intensity after surgical injury in staged bilateral total knee arthroplasty: a randomized, double-blinded, placebo-controlled trial. Br J Anaesth. 2016;117:497. 10.1093/bja/aew227
  12. Chen Y, Zhang Y, Zhu YL, Fu PL. Efficacy and safety of an intra-operative intra-articular magnesium/ropivacaine injection for pain control following total knee arthroplasty. J Int Med Res. 2012;40:2032.
  13. Ekmekci P, Bengisun ZK, Akan B, Kazbek BK, Ozkan KS, et al. The effect of magnesium added to levobupivacaine for femoral nerve block on postoperative analgesia in patients undergoing ACL reconstruction. Knee Surg Sports Traumatol Arthrosc. 2013;21:1119. 10.1007/s00167-012-2093-4
  14. Koltka K, Koknel-Talu G, Asik M, Ozyalcin S. Comparison of efficacy of intraarticular application of magnesium, levobupivacaine and lornoxicam with placebo in arthroscopic surgery. Knee Surg Sports Traumatol Arthrosc. 2011;19:1884. 10.1007/s00167-011-1497-x
  15. Chen Y, Zhang Y, Zhu YL, Fu PL. Efficacy and safety of an intra-operative intra-articular magnesium/ropivacaine injection for pain control following total knee arthroplasty. J Int Med Res. 2009;37:1733.
  16. Farouk S, Aly A. A comparison of intra-articular magnesium and/or morphine with bupivacaine for postoperative analgesia after arthroscopic knee surgery. J Anesth. 2009;23:508. 10.1007/s00540-009-0822-8
image