Magnesium (elemental) (from Magnesium Oxide, Magnesium Citrate and Magnesium Aspartate)
400 mg
95%
Top Medical Research Studies
9
Magnesium sulfate alleviates postoperative pain
Effects of magnesium sulfate on periarticular infiltration analgesia in total knee arthroplasty: a prospective, double-blind, randomized controlled trial.
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Postoperative Pain Relief and Decrease Opioid Consumption: A Prospective Randomized Controlled Trial.
We explored the role of magnesium in reducing knee pain following total knee arthroplasty (TKA). In a study involving 119 adults, participants received either an adductor canal block with magnesium and bupivacaine or just bupivacaine.
Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Read More
9
Magnesium reduces postoperative knee pain
Magnesium sulphate attenuates acute postoperative pain and increased pain intensity after surgical injury in staged bilateral total knee arthroplasty: a randomized, double-blinded, placebo-controlled trial.
We evaluated the impact of magnesium sulphate on pain levels for 44 patients undergoing staged bilateral total knee arthroplasty.
In this study, the magnesium group received magnesium sulphate while the control group received isotonic saline during their surgeries.
Our findings showed that those who received magnesium experienced significantly lower pain scores compared to the control group, both after their first and second surgeries.
Importantly, magnesium also helped reduce the need for additional pain relief medications in the days following surgery.
Read More
Most Useful Reviews
9
Pain relief
6 people found this helpful
It didn't run out of magnesium, and it helped alleviate my knee pain significantly. I appreciated that one capsule meets my daily needs. Excellent brand. Thank you, iHerb, for the fast delivery to Rio de Janeiro; it arrived in just 10 days.
Read More
10
No more pain
5 people found this helpful
My low back pain has vanished! After my daughter recommended magnesium to balance the calcium, I am now completely free from low back pain. Thank you, iHerb!
Read More
9
Miracle supplement
4 people found this helpful
Magnesium is essential! It supports the nervous and cardiovascular systems. For those with knee pain, it is miraculous. My aunt, suffering from osteoarthritis, found relief in her knee pain by taking magnesium every day. I highly recommend it!
Effects of magnesium sulfate on periarticular infiltration analgesia in total knee arthroplasty: a prospective, double-blind, randomized controlled trial.
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Postoperative Pain Relief and Decrease Opioid Consumption: A Prospective Randomized Controlled Trial.
We explored the role of magnesium in reducing knee pain following total knee arthroplasty (TKA). In a study involving 119 adults, participants received either an adductor canal block with magnesium and bupivacaine or just bupivacaine.
Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Read More
9
Magnesium and bupivacaine effective
Intra-Articular Magnesium Plus Bupivacaine Is the Most Effective and Safe Postoperative Analgesic Option Following Knee Arthroscopy: A Network Meta-analysis.
We evaluated how effective magnesium, especially when combined with bupivacaine, is for managing knee pain after arthroscopy. Our study looked at data from 78 randomized trials involving 4,425 participants.
It turns out that magnesium with bupivacaine is the top performer in easing pain right after surgery and at the 24-hour mark, outperforming other analgesics like morphine.
However, magnesium alone didn’t show significant pain relief. We found that using this combination does not lead to more side effects, making it a safe choice for recovery.
Read More
9
Magnesium reduces postoperative knee pain
Magnesium sulphate attenuates acute postoperative pain and increased pain intensity after surgical injury in staged bilateral total knee arthroplasty: a randomized, double-blinded, placebo-controlled trial.
We evaluated the impact of magnesium sulphate on pain levels for 44 patients undergoing staged bilateral total knee arthroplasty.
In this study, the magnesium group received magnesium sulphate while the control group received isotonic saline during their surgeries.
Our findings showed that those who received magnesium experienced significantly lower pain scores compared to the control group, both after their first and second surgeries.
Importantly, magnesium also helped reduce the need for additional pain relief medications in the days following surgery.
Read More
9
Magnesium reduces post-surgery pain
Efficacy and safety of an intra-operative intra-articular magnesium/ropivacaine injection for pain control following total knee arthroplasty.
We looked into how magnesium can help ease knee pain after total knee arthroplasty. In a study of 80 patients, those who received an injection of magnesium sulfate and ropivacaine experienced significantly less pain and needed less morphine compared to those who got a saline injection. This approach not only reduced morphine use in the first 48 hours but also allowed patients to regain movement quicker. Overall, our findings suggest that magnesium may be a beneficial part of pain management in knee surgery.
It didn't run out of magnesium, and it helped alleviate my knee pain significantly. I appreciated that one capsule meets my daily needs. Excellent brand. Thank you, iHerb, for the fast delivery to Rio de Janeiro; it arrived in just 10 days.
Read More
10
No more pain
5 people found this helpful
My low back pain has vanished! After my daughter recommended magnesium to balance the calcium, I am now completely free from low back pain. Thank you, iHerb!
Read More
9
Miracle supplement
4 people found this helpful
Magnesium is essential! It supports the nervous and cardiovascular systems. For those with knee pain, it is miraculous. My aunt, suffering from osteoarthritis, found relief in her knee pain by taking magnesium every day. I highly recommend it!
Read More
9
Calf pain gone
2 people found this helpful
I often woke up at night with calf muscle pain, but after starting magnesium, the discomfort disappeared, and I've continued taking it since.
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9
Knee pain relief
2 people found this helpful
I can't live without this magnesium; my family uses it too. I had knee pain that stopped me from stepping properly, especially at night. After starting Magnesium Dimalate, my pain vanished within a week. My friend had a similar issue, and it worked for her too. It's invaluable for muscle pain and knee pain.
Knee pain is a common condition that can result from various causes, including injuries, overuse, and underlying medical conditions such as arthritis. The knee joint is a complex structure composed of bones, ligaments, tendons, and cartilage, all of which work together to enable movement and support body weight. When any of these components are damaged or inflamed, it can lead to discomfort, stiffness, swelling, and reduced mobility in the affected area.
In many cases, knee pain can manifest as acute pain following an injury, such as a tear in a ligament or cartilage damage. Alternatively, it may develop gradually due to factors like repetitive strain, age-related degeneration, or conditions like osteoarthritis and rheumatoid arthritis. Treatment options vary widely and may include rest, physical therapy, medication, or, in severe cases, surgical interventions. If you're experiencing persistent knee pain, it's advisable to consult with a healthcare professional for an accurate diagnosis and tailored treatment plan.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium is an essential mineral that plays a critical role in numerous bodily functions, including muscle and nerve function, which can be beneficial in managing pain. While it is not a direct treatment for knee pain, some studies suggest that magnesium can help reduce inflammation and improve muscle function, which might alleviate discomfort associated with conditions such as arthritis or strains in the knee area. Magnesium deficiency has also been linked to increased inflammation, so ensuring adequate magnesium levels could potentially support overall joint health.
However, it's important to note that magnesium should not be considered a standalone solution for knee pain. It's best to adopt a comprehensive approach that includes other treatments such as physical therapy, proper exercise, and possibly anti-inflammatory medications recommended by healthcare providers. Always consult with a medical professional before starting any new supplementation, especially if you have existing health concerns or are taking other medications.
Based on user reviews, the time it takes to experience relief from knee pain after starting magnesium supplementation varies, but many report positive results within a week to a month. For instance, one user noted that their knee pain "vanished within a week" of taking Magnesium Dimalate, highlighting its effectiveness for immediate relief Read Review. Another user reported a noticeable improvement after a month of use, indicating that while some may experience faster results, it may take a bit longer for others to feel significant changes Read Review.
Furthermore, several reviewers emphasized the importance of consistent use, suggesting that ongoing supplementation is key to managing chronic pain, with some users noting benefits after two weeks Read Review. Overall, if you're considering magnesium for knee pain, many users recommend patience and regular intake, as individual experiences can greatly vary.
Scientific research suggests that magnesium supplementation may be beneficial for managing knee pain, particularly after surgery. Multiple studies have highlighted the positive impact of magnesium sulfate in postoperative pain relief. For instance, in a controlled trial involving 61 patients who underwent unicompartmental knee arthroplasty, those receiving a modified pain relief cocktail with magnesium reported lower pain medication use and improved recovery compared to those receiving standard treatments [1]. Similarly, another trial with 148 elderly patients showed that magnesium sulfate can enhance recovery quality and decrease early postoperative pain after total knee arthroplasty [2].
In addition, the combination of magnesium with other analgesics, such as bupivacaine, has been found to outperform individual treatments effectively. Studies have shown that patients receiving this combination experienced significantly lower pain scores and reduced reliance on opioids [5]. Overall, the cumulative evidence from these clinical trials indicates that magnesium may serve as a valuable adjunct in pain management protocols for knee surgery, promoting better outcomes and smoother recoveries [3]. However, while the research supports its effectiveness, it's worth noting that individual responses can vary, and magnesium might not be the sole solution for everyone.
Based on user reviews, many individuals have reported significant improvements in their symptoms after starting magnesium supplementation. For instance, users have noted miraculous relief from knee pain, with one stating their pain "vanished within a week" of using Magnesium Dimalate Read Review. Similarly, others shared experiences of their lower back pain completely resolving after incorporating magnesium into their routine, indicating a possible link between magnesium intake and pain management Read Review.
Moreover, many reviewers have emphasized the broader benefits of magnesium beyond just knee and back pain, including reduced muscle cramps and improved sleep quality Read ReviewRead Review. Multiple users reported a noticeable decline in pain levels within a few weeks of consistent use, reinforcing the notion that regular supplementation is vital for optimal results Read Review. It's important to keep in mind that individual experiences can vary, and while many have found relief, results may differ from person to person.
According to user reviews, many individuals have discovered that combining magnesium supplements with other vitamins can enhance their effectiveness in alleviating knee pain. For instance, one user reported significant improvement in their chronic knee pain after taking magnesium alongside vitamin D3, stating they were able to reduce their reliance on painkillers as a result Read Review. Additionally, another review mentioned that taking magnesium with vitamin D and K has helped ease knee pain significantly while also addressing headaches and menstrual discomfort Read Review.
Many users have expressed the benefits of magnesium on its own for knee pain relief, but those who have combined it with other supplements often report more pronounced effects. The integration of vitamin D, in particular, appears to be beneficial as it counteracts magnesium depletion, which might contribute to knee pain. Overall, user experiences suggest that supplementing magnesium with strategic vitamins might yield more effective management of knee pain.
Users generally reported positive experiences with magnesium for treating knee pain, often mentioning dry doses around 400mg as effective. One review noted that taking 400mg daily was ideal for adults and contributed to a fading of back and knee pain Read Review. Others indicated success with a single capsule per day, remarking on significant improvements in knee pain and related symptoms with regular use Read Review.
Several reviews highlighted that users found relief within days to weeks after starting magnesium supplementation, with testimonials ranging from complete pain relief to manageable symptoms. One user reported that their knee pain "vanished within a week" of using Magnesium Dimalate, emphasizing its worth for muscle and knee pain Read Review. Moreover, the combination of magnesium with other supplements, like vitamin D, was frequently mentioned as boosting overall effectiveness in pain management Read Review. Overall, users seem to support a routine involving consistent daily doses of magnesium for optimal results against knee pain.
9
Knee pain relief
2 people found this helpful
I can't live without this magnesium; my family uses it too. I had knee pain that stopped me from stepping properly, especially at night. After starting Magnesium Dimalate, my pain vanished within a week. My friend had a similar issue, and it worked for her too. It's invaluable for muscle pain and knee pain.
7.5
Improved joint pain
2 people found this helpful
After a month of use, I felt a noticeable improvement in my knee pain. Much better now!
9
Back pain reduction
2 people found this helpful
Until I was 28, I hadn't taken magnesium, but then I had severe back pain. Despite doing yoga, it didn’t help. After my endocrinologist suggested magnesium, I was amazed—after two weeks of taking it, the pain disappeared completely! I've continued for two years now. It also aids in insomnia and stress.
10
No more pain
5 people found this helpful
My low back pain has vanished! After my daughter recommended magnesium to balance the calcium, I am now completely free from low back pain. Thank you, iHerb!
7.5
Convenient and effective
5 people found this helpful
I always take this type of magnesium; it is of excellent quality and suits my husband perfectly. It significantly reduces his knee pain, and taking it is easy as the capsules are tasteless—good sleep follows!
4
Reduced leg cramps
I used to wake with leg cramps at night, but since beginning magnesium supplements, their frequency has decreased significantly. I'm grateful I started taking it.
7.5
Chronic pain relief
3 people found this helpful
Taking magnesium with vitamin D3 has improved my chronic knee pain significantly. I’ve reduced the number of painkillers I need. I will continue taking it.
7.5
Joint pain relief
5 people found this helpful
Good magnesium. I take it with vitamin D and K, as D depletes magnesium, leading to knee pain. This magnesium significantly eases my knee pain and headaches and helps with menstrual discomfort. I would highly recommend it.
9
Effective for aches
1 people found this helpful
This product and brand are excellent. After starting magnesium, my back and knee pain faded away. 400mg daily is ideal for adults. Thank you, Us Foods!
9
Eased knee pain
5 people found this helpful
The quality is excellent, and the ingredients are safe. If I take one pill daily, I have no issues sleeping, and my knee pain is manageable. About a week after starting, I felt much better. I recommend taking one pill daily for better results.
8
Magnesium aids post-surgery pain relief
Magnesium sulphate and sodium bicarbonate as additives for periarticular local infiltration analgesia improve pain management after unicompartmental knee arthroplasty: a prospective, double-blind, randomized controlled trial.
We investigated the impact of magnesium sulphate in pain management for patients after unicompartmental knee arthroplasty (UKA). In a controlled trial, 61 patients received either a modified pain relief cocktail with magnesium or a traditional one.
Results showed that the modified cocktail led to less pain medication use and improved early joint recovery. In other words, magnesium seemed to enhance pain control and recovery without the use of additional drugs.
7
Magnesium aids knee surgery recovery
Effect of Magnesium Sulfate Infusion on Postoperative Quality of Recovery in Patients Undergoing Total Knee Arthroplasty: A Prospective, Double-Blind, Randomized Controlled Trial.
We investigated how magnesium sulfate influences recovery after knee surgery. In our study, 148 elderly patients undergoing total knee arthroplasty were divided into two groups: one received magnesium sulfate, while the other received a saline solution.
This double-blind setup allowed us to see if magnesium sulfate could enhance recovery quality after surgery. Our findings indicate that magnesium sulfate does help reduce early postoperative pain and improves overall recovery in these patients.
Overall, magnesium sulfate appears beneficial in managing pain during the recovery process.
9
Magnesium aids postoperative pain relief
Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Postoperative Pain Relief and Decrease Opioid Consumption: A Prospective Randomized Controlled Trial.
We explored the role of magnesium in reducing knee pain following total knee arthroplasty (TKA). In a study involving 119 adults, participants received either an adductor canal block with magnesium and bupivacaine or just bupivacaine.
Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
9
Magnesium sulfate alleviates postoperative pain
Effects of magnesium sulfate on periarticular infiltration analgesia in total knee arthroplasty: a prospective, double-blind, randomized controlled trial.
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Zhu Y, Shen S, Cui L, Wu L, Zhang B. Magnesium sulphate and sodium bicarbonate as additives for periarticular local infiltration analgesia improve pain management after unicompartmental knee arthroplasty: a prospective, double-blind, randomized controlled trial. J Orthop Surg Res. 2024;19:764. 10.1186/s13018-024-05233-6
Xu H, Hao C, Wang X, Du J, Zhang T, et al. Effect of Magnesium Sulfate Infusion on Postoperative Quality of Recovery in Patients Undergoing Total Knee Arthroplasty: A Prospective, Double-Blind, Randomized Controlled Trial. Drug Des Devel Ther. 2024;18:919. 10.2147/DDDT.S444896
Zhao C, Wang L, Chen L, Wang Q, Kang P. Effects of magnesium sulfate on periarticular infiltration analgesia in total knee arthroplasty: a prospective, double-blind, randomized controlled trial. J Orthop Surg Res. 2023;18:301. 10.1186/s13018-023-03790-w
Wang Q, Zhao C, Hu J, Ma T, Yang J, et al. Efficacy of a Modified Cocktail for Periarticular Local Infiltration Analgesia in Total Knee Arthroplasty: A Prospective, Double-Blinded, Randomized Controlled Trial. J Bone Joint Surg Am. 2023;105:354. 10.2106/JBJS.22.00614
Choi JW, Lahori A, Merlo JA, Gill O, Ghoddoussi F, et al. Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Postoperative Pain Relief and Decrease Opioid Consumption: A Prospective Randomized Controlled Trial. Clin J Pain. 2022;38:388. 10.1097/AJP.0000000000001036
He Y, He H, Li X, Lei G, Xie D, et al. Intra-Articular Magnesium Plus Bupivacaine Is the Most Effective and Safe Postoperative Analgesic Option Following Knee Arthroscopy: A Network Meta-analysis. Arthroscopy. 2022;38:2897. 10.1016/j.arthro.2022.03.013
Shi L, Zhu H, Ma J, Shi LL, Gao F, et al. Intra-articular magnesium to alleviate postoperative pain after arthroscopic knee surgery: a meta-analysis of randomized controlled trials. J Orthop Surg Res. 2021;16:111. 10.1186/s13018-021-02264-1
Zhao Z, Zhang X, Peng H, Li W, Liu H, et al. Magnesium Sulfate Combined with a Levobupivacaine Periarticular Cocktail for Analgesia in the Early Postoperative Period after Total Knee Arthroplasty. J Knee Surg. 2021;34:1463. 10.1055/s-0040-1710364
Condello V, Filardo G, Madonna V, Andriolo L, Screpis D, et al. Use of a Biomimetic Scaffold for the Treatment of Osteochondral Lesions in Early Osteoarthritis. Biomed Res Int. 2018;2018:7937089. 10.1155/2018/7937089
Shmagel A, Onizuka N, Langsetmo L, Vo T, Foley R, et al. Low magnesium intake is associated with increased knee pain in subjects with radiographic knee osteoarthritis: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2018;26:651. 10.1016/j.joca.2018.02.002
Shin HJ, Kim EY, Na HS, Kim TK, Kim MH, et al. Magnesium sulphate attenuates acute postoperative pain and increased pain intensity after surgical injury in staged bilateral total knee arthroplasty: a randomized, double-blinded, placebo-controlled trial. Br J Anaesth. 2016;117:497. 10.1093/bja/aew227
Chen Y, Zhang Y, Zhu YL, Fu PL. Efficacy and safety of an intra-operative intra-articular magnesium/ropivacaine injection for pain control following total knee arthroplasty. J Int Med Res. 2012;40:2032.
Ekmekci P, Bengisun ZK, Akan B, Kazbek BK, Ozkan KS, et al. The effect of magnesium added to levobupivacaine for femoral nerve block on postoperative analgesia in patients undergoing ACL reconstruction. Knee Surg Sports Traumatol Arthrosc. 2013;21:1119. 10.1007/s00167-012-2093-4
Koltka K, Koknel-Talu G, Asik M, Ozyalcin S. Comparison of efficacy of intraarticular application of magnesium, levobupivacaine and lornoxicam with placebo in arthroscopic surgery. Knee Surg Sports Traumatol Arthrosc. 2011;19:1884. 10.1007/s00167-011-1497-x
Chen Y, Zhang Y, Zhu YL, Fu PL. Efficacy and safety of an intra-operative intra-articular magnesium/ropivacaine injection for pain control following total knee arthroplasty. J Int Med Res. 2009;37:1733.
Farouk S, Aly A. A comparison of intra-articular magnesium and/or morphine with bupivacaine for postoperative analgesia after arthroscopic knee surgery. J Anesth. 2009;23:508. 10.1007/s00540-009-0822-8