Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
USERS' SCORE
Good
Based on 17 Reviews
8
Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Vitamin D-3 (as Cholecalciferol)
25 mcg (1,000 IU)
125%
Calcium (from Aquamin® TG Seaweed Derived Minerals and Calcium Citrate)
400 mg
31%
Magnesium (from Magnesium Oxide, Magnesium Glycinate, Magnesium Taurinate, Magnesium Citrate and Aquamin® TG Seaweed Derived Minerals)
800 mg
190%
Zinc (from L-OptiZinc® Monomethionine)
15 mg
136%
Top Medical Research Studies
8
We explored how zinc might help in treating and preventing the common cold. The study focused on zinc's effects, isolating it from other treatments to understand its true impact on cold symptoms. By doing this, the researchers aimed to clarify whether zinc could genuinely shorten the duration of a cold or alleviate its symptoms.
The findings were intriguing but showed that zinc might not yield significant benefits for everyone. While some individuals reported a slight reduction in cold symptoms, the evidence did not strongly support zinc as an effective treatment overall.
This means that, for those seeking relief from a nasty cold, zinc alone might not be the go-to solution we hoped it would be. It’s essential to consider this information when deciding on a cold treatment plan and to approach zinc with realistic expectations.
The findings were intriguing but showed that zinc might not yield significant benefits for everyone. While some individuals reported a slight reduction in cold symptoms, the evidence did not strongly support zinc as an effective treatment overall.
This means that, for those seeking relief from a nasty cold, zinc alone might not be the go-to solution we hoped it would be. It’s essential to consider this information when deciding on a cold treatment plan and to approach zinc with realistic expectations.
Read More
8
We examined how incorporating fly ash into magnesium phosphate repair mortar (MPM) influences its effectiveness in cold environments. Our investigation revealed that fly ash modifies the microstructure of the MPM, enhancing its performance without affecting the setting time or fluidity significantly.
We discovered that adding 10% to 15% fly ash improves the mechanical strength, adhesion, water resistance, and stability of the mortar. Notably, we found that the curing temperature plays a critical role; as the temperature rises, compressive strength increases, while properties like flexural strength decrease.
Interestingly, even when cured in icy conditions at -20°C or 0°C, MPM with fly ash retains good early strength and strong adhesion properties. This suggests magnesium phosphate repair mortar modified with fly ash is suitable for emergency repairs in cold weather, showcasing its potential for use in challenging environments.
We discovered that adding 10% to 15% fly ash improves the mechanical strength, adhesion, water resistance, and stability of the mortar. Notably, we found that the curing temperature plays a critical role; as the temperature rises, compressive strength increases, while properties like flexural strength decrease.
Interestingly, even when cured in icy conditions at -20°C or 0°C, MPM with fly ash retains good early strength and strong adhesion properties. This suggests magnesium phosphate repair mortar modified with fly ash is suitable for emergency repairs in cold weather, showcasing its potential for use in challenging environments.
Read More
9
We examined the use of copper-magnesium (CuMg) alloys, particularly focusing on those with higher magnesium content, to understand how they perform during cold metal working processes. Our testing aimed to identify the effects of magnesium on the mechanical properties and workability of these alloys, as they’re known to provide significant solid-solution hardening.
The results revealed that CuMg alloys with 2 to 4 weight percent (wt%) magnesium displayed impressive strength characteristics, outperforming commonly used materials like pure copper and aluminum. We calculated improvements in hardness and Ultimate Tensile Strength (UTS), showing increases of up to two and a half times compared to pure copper. However, we noted that while magnesium enhances strength, it also raises friction during processing, which can complicate metal forming.
We learned that increasing magnesium content could lead to brittleness when it exceeded approximately 3.6 wt%, introducing challenges for cold working. This brittleness arises from the formation of specific phases, making it challenging to use these alloys in practical applications. Our findings suggest that while magnesium can significantly boost the mechanical properties of CuMg alloys, careful consideration is needed regarding its maximum content to maintain ductility and workability.
The results revealed that CuMg alloys with 2 to 4 weight percent (wt%) magnesium displayed impressive strength characteristics, outperforming commonly used materials like pure copper and aluminum. We calculated improvements in hardness and Ultimate Tensile Strength (UTS), showing increases of up to two and a half times compared to pure copper. However, we noted that while magnesium enhances strength, it also raises friction during processing, which can complicate metal forming.
We learned that increasing magnesium content could lead to brittleness when it exceeded approximately 3.6 wt%, introducing challenges for cold working. This brittleness arises from the formation of specific phases, making it challenging to use these alloys in practical applications. Our findings suggest that while magnesium can significantly boost the mechanical properties of CuMg alloys, careful consideration is needed regarding its maximum content to maintain ductility and workability.
Read More
Most Useful Reviews
9
Cold sensitivity reduced
9 people found this helpful
Initially, I was troubled by tooth sensitivity, particularly to cold food. However, after commencing this vitamin course, I saw a marked reduction in sensitivity after about 10 days. I'm pleased to report that it has now completely resolved.
Read More
7.5
Cold symptom alleviation
3 people found this helpful
Magnesium and Calcium are essential for good health. This product, which includes Zinc, is perfect as it allows the body's proper metabolism of calcium. It has minimal side effects, and I’ve noticed it helps lessen symptoms associated with the common cold.
Read More
9
Cramps disappeared
A good product that I use for leg cramps and as a preventive measure against colds during winter. My calf muscles were cramping intensely, but after using this supplement, that issue has completely disappeared.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
- All Researches
9
Magnesium enhances vascular preservation
We examined the effectiveness of modified Krebs-Henseleit (KH) solutions with low calcium and high magnesium levels on preserving vascular function during cold storage. Our focus was on whether adding adenosine and lidocaine could further improve the preservation of rat aortic rings after six days of cold preservation.
In our study, we found that traditional preservation solutions often fail to maintain proper vascular function after just three days of cold storage. However, when we tested a modified KH solution with lower calcium and higher magnesium, we observed significant recovery of contraction and relaxation functions in the aortic rings. This suggests that magnesium plays a vital role in preserving these functions.
Interestingly, while adding adenosine and lidocaine did not enhance contraction, it did improve the aortic rings' ability to relax in response to a chemical called acetylcholine. Furthermore, a histological examination showed that the addition of adenosine positively affected the endothelial lining and structural integrity of the vessels, highlighting its importance in cold preservation.
Overall, our findings suggest that magnesium in combination with adenosine significantly enhances the preservation of vascular structures and functionalities during extended cold storage, making it an important consideration for vascular grafts.
In our study, we found that traditional preservation solutions often fail to maintain proper vascular function after just three days of cold storage. However, when we tested a modified KH solution with lower calcium and higher magnesium, we observed significant recovery of contraction and relaxation functions in the aortic rings. This suggests that magnesium plays a vital role in preserving these functions.
Interestingly, while adding adenosine and lidocaine did not enhance contraction, it did improve the aortic rings' ability to relax in response to a chemical called acetylcholine. Furthermore, a histological examination showed that the addition of adenosine positively affected the endothelial lining and structural integrity of the vessels, highlighting its importance in cold preservation.
Overall, our findings suggest that magnesium in combination with adenosine significantly enhances the preservation of vascular structures and functionalities during extended cold storage, making it an important consideration for vascular grafts.
Read More
9
Magnesium improves beef storage safety
We explored the effects of incorporating hydrogen-producing magnesium into minced beef meat (MBM) to see how it affects quality and safety during cold storage. The study involved vacuum packaging the MBMs and storing them at 4°C for 12 days while comparing them with other treatments, such as gassing with hydrogen or nitrogen.
What we found was quite promising. The samples with magnesium showed the lowest browning index values, which indicates less color change and better visual quality. Additionally, these samples exhibited reduced bacterial counts, including mesophilic and psychrotrophic bacteria, as well as yeast and molds. This suggests that magnesium can help in maintaining the freshness and safety of the meat.
Interestingly, the magnesium treatment also limited the formation of potentially harmful compounds, such as thiobarbituric acid reactive substances and biogenic amines, which can negatively impact meat quality. By the end of the storage period, the control samples had the highest levels of volatile compounds, hinting at spoilage, while magnesium-enhanced and vacuum-packaged samples fared better.
Overall, we observed that using hydrogen-producing magnesium while handling minced beef could be an effective way to protect important quality attributes and safety during cold storage.
What we found was quite promising. The samples with magnesium showed the lowest browning index values, which indicates less color change and better visual quality. Additionally, these samples exhibited reduced bacterial counts, including mesophilic and psychrotrophic bacteria, as well as yeast and molds. This suggests that magnesium can help in maintaining the freshness and safety of the meat.
Interestingly, the magnesium treatment also limited the formation of potentially harmful compounds, such as thiobarbituric acid reactive substances and biogenic amines, which can negatively impact meat quality. By the end of the storage period, the control samples had the highest levels of volatile compounds, hinting at spoilage, while magnesium-enhanced and vacuum-packaged samples fared better.
Overall, we observed that using hydrogen-producing magnesium while handling minced beef could be an effective way to protect important quality attributes and safety during cold storage.
Read More
9
We examined the use of copper-magnesium (CuMg) alloys, particularly focusing on those with higher magnesium content, to understand how they perform during cold metal working processes. Our testing aimed to identify the effects of magnesium on the mechanical properties and workability of these alloys, as they’re known to provide significant solid-solution hardening.
The results revealed that CuMg alloys with 2 to 4 weight percent (wt%) magnesium displayed impressive strength characteristics, outperforming commonly used materials like pure copper and aluminum. We calculated improvements in hardness and Ultimate Tensile Strength (UTS), showing increases of up to two and a half times compared to pure copper. However, we noted that while magnesium enhances strength, it also raises friction during processing, which can complicate metal forming.
We learned that increasing magnesium content could lead to brittleness when it exceeded approximately 3.6 wt%, introducing challenges for cold working. This brittleness arises from the formation of specific phases, making it challenging to use these alloys in practical applications. Our findings suggest that while magnesium can significantly boost the mechanical properties of CuMg alloys, careful consideration is needed regarding its maximum content to maintain ductility and workability.
The results revealed that CuMg alloys with 2 to 4 weight percent (wt%) magnesium displayed impressive strength characteristics, outperforming commonly used materials like pure copper and aluminum. We calculated improvements in hardness and Ultimate Tensile Strength (UTS), showing increases of up to two and a half times compared to pure copper. However, we noted that while magnesium enhances strength, it also raises friction during processing, which can complicate metal forming.
We learned that increasing magnesium content could lead to brittleness when it exceeded approximately 3.6 wt%, introducing challenges for cold working. This brittleness arises from the formation of specific phases, making it challenging to use these alloys in practical applications. Our findings suggest that while magnesium can significantly boost the mechanical properties of CuMg alloys, careful consideration is needed regarding its maximum content to maintain ductility and workability.
Read More
9
We explored the impact of zinc-amino acids chelate on cold stress resistance in machine-transplanted early rice. Our investigation included other cold-resistant agents like uniconazole and abscisic acid, but we found zinc to be particularly effective. When applied during the regreening stage, zinc notably enhanced rice growth by promoting tillering and increasing the leaf area, which led to better yields.
We noted that zinc-amino acids chelate improved antioxidant enzyme activities, which are crucial for helping rice withstand cold temperatures. The yield of rice treated with zinc was approximately 9.22% higher than with uniconazole and 7.14% higher than with abscisic acid.
Additionally, we observed that using 750 g/ha of zinc-amino acids chelate during the transplanting and regreening stages yielded the best results. The timing of the application played a critical role, as spraying during these specific phases maximized both yield and cold resistance.
Overall, zinc treatments stand out as a promising option for improving cold stress resilience in early rice, making it a key consideration for farmers dealing with cold climate conditions.
We noted that zinc-amino acids chelate improved antioxidant enzyme activities, which are crucial for helping rice withstand cold temperatures. The yield of rice treated with zinc was approximately 9.22% higher than with uniconazole and 7.14% higher than with abscisic acid.
Additionally, we observed that using 750 g/ha of zinc-amino acids chelate during the transplanting and regreening stages yielded the best results. The timing of the application played a critical role, as spraying during these specific phases maximized both yield and cold resistance.
Overall, zinc treatments stand out as a promising option for improving cold stress resilience in early rice, making it a key consideration for farmers dealing with cold climate conditions.
Read More
8
We examined how incorporating fly ash into magnesium phosphate repair mortar (MPM) influences its effectiveness in cold environments. Our investigation revealed that fly ash modifies the microstructure of the MPM, enhancing its performance without affecting the setting time or fluidity significantly.
We discovered that adding 10% to 15% fly ash improves the mechanical strength, adhesion, water resistance, and stability of the mortar. Notably, we found that the curing temperature plays a critical role; as the temperature rises, compressive strength increases, while properties like flexural strength decrease.
Interestingly, even when cured in icy conditions at -20°C or 0°C, MPM with fly ash retains good early strength and strong adhesion properties. This suggests magnesium phosphate repair mortar modified with fly ash is suitable for emergency repairs in cold weather, showcasing its potential for use in challenging environments.
We discovered that adding 10% to 15% fly ash improves the mechanical strength, adhesion, water resistance, and stability of the mortar. Notably, we found that the curing temperature plays a critical role; as the temperature rises, compressive strength increases, while properties like flexural strength decrease.
Interestingly, even when cured in icy conditions at -20°C or 0°C, MPM with fly ash retains good early strength and strong adhesion properties. This suggests magnesium phosphate repair mortar modified with fly ash is suitable for emergency repairs in cold weather, showcasing its potential for use in challenging environments.
Read More
User Reviews
USERS' SCORE
Good
Based on 17 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Cold sensitivity reduced
9 people found this helpful
Initially, I was troubled by tooth sensitivity, particularly to cold food. However, after commencing this vitamin course, I saw a marked reduction in sensitivity after about 10 days. I'm pleased to report that it has now completely resolved.
Read More
7.5
Cold symptom alleviation
3 people found this helpful
Magnesium and Calcium are essential for good health. This product, which includes Zinc, is perfect as it allows the body's proper metabolism of calcium. It has minimal side effects, and I’ve noticed it helps lessen symptoms associated with the common cold.
Read More
9
Cramps disappeared
A good product that I use for leg cramps and as a preventive measure against colds during winter. My calf muscles were cramping intensely, but after using this supplement, that issue has completely disappeared.
Read More
9
Eases cold symptoms
For colds, I give it to my niece, who is 4 years old, at the first sign of a cold, we dribble it under her tongue every half hour, an hour, before bedtime. Colds are easier to manage; sometimes they recede! We have been using this for the second year now; it’s essential for our first-aid kit during the cold season.
Read More
9
Effective cold remedy
Excellent! This remedy for colds surpassed my expectations; I really like it.
Read More
Frequently Asked Questions
9
Cold sensitivity reduced
9 people found this helpful
Initially, I was troubled by tooth sensitivity, particularly to cold food. However, after commencing this vitamin course, I saw a marked reduction in sensitivity after about 10 days. I'm pleased to report that it has now completely resolved.
9
Eases cold symptoms
For colds, I give it to my niece, who is 4 years old, at the first sign of a cold, we dribble it under her tongue every half hour, an hour, before bedtime. Colds are easier to manage; sometimes they recede! We have been using this for the second year now; it’s essential for our first-aid kit during the cold season.
6
Colds quickly recede
This product has a beneficial composition for recovery from illness; however, I believe the vitamin D3 dosage is too low. Still, I have noticed positive effects. I even give it to my parents and grandmother, and colds or acute respiratory infections seem to recede quickly, or they don't get sick at all after contact.
9
Teeth sensitivity vanished
An excellent complex for supporting teeth, bones, and the nervous system! I had severe sensitivity to cold and bitter, but after just one week of taking these, all symptoms disappeared, including the sensitivity of my teeth. Magnesium also contributed to better sleep.
8
Easier cold recovery
An excellent complex! We take 2 capsules each with Omega. We tolerate colds more easily, and my husband’s fluctuating blood pressure has normalised. My hair is no longer falling out, and my nails are stronger. It’s a must-have for everyone!
7.5
Prevents cold illness
I recommend this during the cold season and widespread epidemics. Many around me are ill, but I am not; minor cold symptoms passed quickly. Its composition includes zinc, crucial for immunity. Calcium and magnesium have positively impacted my general health; I usually experience issues during this off-season.
7.5
Heart health improved
I bought this for my mother as she has heart issues and arteriosclerosis. She reported feeling much better after taking it, with more energy and a notable decrease in colds during cold weather, including the recent coronavirus. I am very pleased with this product and will continue purchasing it.
7.5
Energy and cold resistance
90 people found this helpful
I've been taking this vitamin for a month and already notice a difference. It’s an excellent family supplement that has significantly boosted my energy levels and mood. Moreover, it has enhanced my resistance to colds and seems to benefit my skin.
8
We explored the impact of regular gargling with an antimicrobial mouthwash that contains both cetylpyridinium chloride and zinc on upper respiratory symptoms. A total of 150 participants were split into two groups; one group just brushed their teeth, while the other group brushed and gargled with the mouthwash twice a day over three months.
Our findings revealed that those using the mouthwash experienced a 21.5% reduction in the frequency and an 11% decrease in the severity of respiratory symptoms. This strongly suggests that incorporating zinc, alongside cetylpyridinium chloride, can provide benefits for those suffering from cold-related symptoms.
However, it’s important to note that this study’s design involved multiple components, and we can’t isolate zinc’s effectiveness from the impact of the other ingredients. Still, the results encourage us to view mouthwash with these ingredients as a helpful addition to our daily hygiene routines, especially during cold and flu season.
Ultimately, this research indicates that gargling with a mouthwash containing zinc and cetylpyridinium chloride can indeed help alleviate some unpleasant cold symptoms, but we should be mindful of the combination's effects when interpreting these outcomes.
Our findings revealed that those using the mouthwash experienced a 21.5% reduction in the frequency and an 11% decrease in the severity of respiratory symptoms. This strongly suggests that incorporating zinc, alongside cetylpyridinium chloride, can provide benefits for those suffering from cold-related symptoms.
However, it’s important to note that this study’s design involved multiple components, and we can’t isolate zinc’s effectiveness from the impact of the other ingredients. Still, the results encourage us to view mouthwash with these ingredients as a helpful addition to our daily hygiene routines, especially during cold and flu season.
Ultimately, this research indicates that gargling with a mouthwash containing zinc and cetylpyridinium chloride can indeed help alleviate some unpleasant cold symptoms, but we should be mindful of the combination's effects when interpreting these outcomes.
8
We explored how zinc might help in treating and preventing the common cold. The study focused on zinc's effects, isolating it from other treatments to understand its true impact on cold symptoms. By doing this, the researchers aimed to clarify whether zinc could genuinely shorten the duration of a cold or alleviate its symptoms.
The findings were intriguing but showed that zinc might not yield significant benefits for everyone. While some individuals reported a slight reduction in cold symptoms, the evidence did not strongly support zinc as an effective treatment overall.
This means that, for those seeking relief from a nasty cold, zinc alone might not be the go-to solution we hoped it would be. It’s essential to consider this information when deciding on a cold treatment plan and to approach zinc with realistic expectations.
The findings were intriguing but showed that zinc might not yield significant benefits for everyone. While some individuals reported a slight reduction in cold symptoms, the evidence did not strongly support zinc as an effective treatment overall.
This means that, for those seeking relief from a nasty cold, zinc alone might not be the go-to solution we hoped it would be. It’s essential to consider this information when deciding on a cold treatment plan and to approach zinc with realistic expectations.
References
- Arsyad A, Lembang GKR, Linda SL, Djabir YY, Dobson GP. Low Calcium-High Magnesium Krebs-Henseleit Solution Combined with Adenosine and Lidocaine Improved Rat Aortic Function and Structure Following Cold Preservation. Medicina (Kaunas). 2024;60. 10.3390/medicina60081284
- Liu J, Zhang J, Li A, Xia X, Chen J. Effect of fly ash and curing temperature on the properties of magnesium phosphate repair mortar. Sci Rep. 2024;14:15512. 10.1038/s41598-024-66581-1
- Çelebi Y, Kavrut E, Bulut M, Çetintaş Y, Tekin A, et al. Incorporation of hydrogen-producing magnesium into minced beef meat protects the quality attributes and safety of the product during cold storage. Food Chem. 2024;448:139185. 10.1016/j.foodchem.2024.139185
- Strzępek P, Zasadzińska M. Prospective cold metal working and analysis of deformation susceptibility of CuMg alloys with high magnesium content. Sci Rep. 2024;14:6447. 10.1038/s41598-024-57083-1
- Muniz FWMG, Casarin M, Pola NM, Rösing CK, Silveira TMD, et al. Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms. PLoS One. 2025;20:e0316807. 10.1371/journal.pone.0316807
- Wieland LS. Zinc for prevention and treatment of the common cold: Summary of a Cochrane review. Explore (NY). 2025;21:103111. 10.1016/j.explore.2025.103111
- Yuan S, Qin S, Shi Q, Chen P, Tu N, et al. Effects of different cold-resistant agents and application methods on yield and cold-resistance of machine-transplanted early rice. Front Plant Sci. 2024;15:1422374. 10.3389/fpls.2024.1422374
