Overview

SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.8
USERS' SCORE
Good
Based on 33 Reviews
8.2
Supplement Facts
Serving Size: 3 Veg Capsules
Amount Per Serving
%DV
Magnesium (elemental) (from 2,667 mg Magnesium Citrate)
400 mg
95%

Top Medical Research Studies

8
Magnesium's impact on heart health
We examined the connection between dietary magnesium and cardiovascular disease, focusing on how magnesium intake or serum levels relate to heart health. Over the last couple of decades, numerous studies have shown that low magnesium levels are associated with several heart-related issues, including high blood pressure, heart attacks, and even heart failure.

Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.

Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.
Read More
We investigated how magnesium impacts cardiovascular health, particularly its role in a condition known as arteriosclerosis. This disease can lead to serious heart complications, but recent studies revealed magnesium's potential benefits.

In a series of experiments involving human cells and animal models, we discovered that magnesium effectively reduces a process called ferroptosis, which is linked to the progression of arteriosclerosis. It appears that magnesium ions play a vital role by preventing certain proteins from breaking down. This action promotes the expression of protective proteins while reducing harmful components that contribute to the disease.

Notably, our animal tests highlighted that biodegradable magnesium stents not only hinder ferroptosis but also slow down the advancement of arteriosclerosis. This suggests that magnesium-based treatments could offer a promising avenue for combating cardiovascular diseases effectively.
Read More
8
Magnesium linked to cardiovascular health
We examined how magnesium levels in the blood could influence the risk of death from cardiovascular issues in patients with advanced chronic kidney disease (CKD). Our study tracked 1,271 individuals with CKD stages 4 and 5 over a decade, focusing on those who had not previously experienced major heart-related events.

We discovered that higher serum magnesium concentrations were linked to lower risks of dying from conditions like heart failure, coronary heart disease, and stroke. By stratifying patients based on their magnesium levels, we found that those in the highest group experienced significantly better outcomes.

This suggests that maintaining adequate magnesium levels might be important for protecting cardiovascular health in these patients. While it’s just one piece of the puzzle, our findings highlight the potential benefits of magnesium as a factor worth considering in the management of cardiovascular risks.
Read More

Most Useful Reviews

9
Essential for health
240 people found this helpful
I recommend magnesium to all my patients as it is crucial for many bodily functions including those essential for cardiovascular disease. Deficiency can lead to several issues like fatigue and heartburn. It's best to use various forms for optimal benefits.
Read More
9
Consistent quality
3 people found this helpful
I regularly purchase this magnesium for my mother and me. It's effective in managing cardiovascular disease, improves overall health, and is well-tolerated with no side effects.
Read More
7.5
Sedative effect
3 people found this helpful
Magnesium citrate is excellent for managing cardiovascular disease and has a sedative quality, helping me to relax and sleep better at night.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.8
  • All Researches
We investigated how magnesium impacts cardiovascular health, particularly its role in a condition known as arteriosclerosis. This disease can lead to serious heart complications, but recent studies revealed magnesium's potential benefits.

In a series of experiments involving human cells and animal models, we discovered that magnesium effectively reduces a process called ferroptosis, which is linked to the progression of arteriosclerosis. It appears that magnesium ions play a vital role by preventing certain proteins from breaking down. This action promotes the expression of protective proteins while reducing harmful components that contribute to the disease.

Notably, our animal tests highlighted that biodegradable magnesium stents not only hinder ferroptosis but also slow down the advancement of arteriosclerosis. This suggests that magnesium-based treatments could offer a promising avenue for combating cardiovascular diseases effectively.
Read More
8
Magnesium linked to cardiovascular health
We examined how magnesium levels in the blood could influence the risk of death from cardiovascular issues in patients with advanced chronic kidney disease (CKD). Our study tracked 1,271 individuals with CKD stages 4 and 5 over a decade, focusing on those who had not previously experienced major heart-related events.

We discovered that higher serum magnesium concentrations were linked to lower risks of dying from conditions like heart failure, coronary heart disease, and stroke. By stratifying patients based on their magnesium levels, we found that those in the highest group experienced significantly better outcomes.

This suggests that maintaining adequate magnesium levels might be important for protecting cardiovascular health in these patients. While it’s just one piece of the puzzle, our findings highlight the potential benefits of magnesium as a factor worth considering in the management of cardiovascular risks.
Read More
8
Magnesium linked to heart health
We explored the connection between dietary magnesium intake and cardiovascular disease, particularly in people living with diabetes. This study analyzed data from a large group of over 5,000 individuals who participated in the National Health and Nutrition Examination Survey over nearly two decades.

By utilizing advanced statistical methods, researchers identified key dietary factors that could predict long-term mortality risks. Notably, they found that higher intakes of dietary fiber and magnesium were associated with a decreased risk of both all-cause and cardiovascular-related deaths among people with diabetes. The analysis revealed a clear trend: as magnesium intake increased, the risk of cardiovascular mortality decreased.

The study suggests that incorporating more magnesium-rich foods could play a vital role in managing heart health for those with diabetes. By making informed dietary choices, individuals may enhance their longevity and reduce the risk of serious health complications.
Read More
8
Magnesium impacts blood sugar control
We explored the connections between magnesium (Mg), calcium (Ca), and abnormal levels of HbA1c—a key marker for blood sugar management—in adults with coronary artery disease (CAD). Our research involved a substantial group of 11,934 patients, allowing us to gain valuable insights into how these minerals impact cardiovascular health.

Our findings reveal a noteworthy association: higher serum magnesium levels appear to be linked to lower HbA1c concentrations. Specifically, patients with higher magnesium levels showed a significant decrease in the likelihood of having abnormal HbA1c readings. In contrast, calcium levels did not demonstrate a similar beneficial effect; they were not associated with abnormal HbA1c levels at all.

Interestingly, we also noted that while magnesium correlates with better fasting blood glucose outcomes, higher calcium levels were actually associated with worse results. Additionally, our analysis indicated that inflammation, as gauged by a specific blood marker, didn't mediate the relationship between magnesium and HbA1c. This suggests that magnesium might play a direct role in blood sugar regulation, separate from inflammation's influence.

Overall, our study highlights magnesium's potential importance in managing blood sugar levels among individuals with heart disease, pointing to a promising area for future research and potential dietary considerations.
Read More
8
Magnesium's impact on HFpEF mortality
We explored how magnesium supplementation affects mortality rates in patients with heart failure with preserved ejection fraction (HFpEF), a subset of heart failure where treatment options are limited. The study analyzed data from the MIMIC-IV database, focusing on patients from 2008 to 2019. Using a technique called propensity score matching, we aimed to create a balanced comparison between those who received magnesium supplements and those who did not.

Our primary focus was on the 28-day all-cause mortality rate, along with secondary analyses of ICU stays, one-year mortality, and overall hospitalization duration. In total, we evaluated 1,970 patients, splitting them evenly between the magnesium and non-magnesium groups. The outcomes were striking: magnesium intake was associated with a significant reduction in mortality within the first 28 days, particularly benefiting older adults, women, and individuals with hypertension.

While magnesium supplementation showed promise in reducing mortality and also improved longer-term outcomes, we noted that it was linked to longer stays in both ICU and hospital settings. Interestingly, we found that blood urea nitrogen levels may play a role in mediating the relationship between magnesium intake and mortality, suggesting a more complex interaction at play.

This research highlights the potential of magnesium as a valuable treatment for those grappling with HFpEF, especially certain at-risk groups. As we consider these findings, further research is needed to explore magnesium's effects more thoroughly and understand its full implications for patient care.
Read More

User Reviews

USERS' SCORE
Good
Based on 33 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Essential for health
240 people found this helpful
I recommend magnesium to all my patients as it is crucial for many bodily functions including those essential for cardiovascular disease. Deficiency can lead to several issues like fatigue and heartburn. It's best to use various forms for optimal benefits.
Read More
9
Consistent quality
3 people found this helpful
I regularly purchase this magnesium for my mother and me. It's effective in managing cardiovascular disease, improves overall health, and is well-tolerated with no side effects.
Read More
7.5
Sedative effect
3 people found this helpful
Magnesium citrate is excellent for managing cardiovascular disease and has a sedative quality, helping me to relax and sleep better at night.
Read More
9
Supports cardiovascular health
2 people found this helpful
Magnesium citrate is readily absorbed and beneficial for overall health. It significantly aids in reducing muscle cramps, promoting digestion, and supporting cardiovascular disease health. For anyone seeking an effective and bioavailable magnesium supplement, this is an excellent option.
Read More
9
Eases anxiety symptoms
2 people found this helpful
I repeatedly order this magnesium as it effectively supports my nervous system and alleviates anxiety. It helps me recover in the gym, notably reducing muscle pain, and also contributes to my cardiovascular health.
Read More

Frequently Asked Questions

7.5
Strengthens nerves
Magnesium plays a vital role in various bodily processes. Insufficient levels can heighten the risk of cardiovascular disease. After a two-month course, I've found my nerves are stronger, which has significantly reduced my stress.
9
Improves sleep quality
1 people found this helpful
I bought this magnesium for both my wife and myself. It greatly benefits my nervous system and enhances sleep quality. I've experienced relief from leg cramps after just one capsule. The magnesium citrate also has a mild laxative effect, which I find helpful, as I occasionally suffer from constipation. The only downside is the large capsules, but I managed to adjust. Overall, this magnesium is excellent for cardiovascular disease and other related conditions.
9
Supports immune health
Magnesium Citrate, 400 mg, is superb for maintaining health. It aids the cardiovascular system, promotes normal functioning of muscles and the nervous system, and improves sleep. The capsules are easy to take, providing rapid benefits.
7.5
Normalises blood pressure
2 people found this helpful
Magnesium citrate helps normalise blood pressure and offers a calming effect beneficial for sleep disturbances and nervousness. I recommend it for its positive effects on cardiovascular disease and muscle spasms.
9
Soothes nervous system
2 people found this helpful
Magnesium is vital for cardiovascular disease health, bone strength, and nervous system function. After taking two capsules before bed, I noticed improvements in sleep quality and a calming effect overall.
7.5
Improved sleep
23 people found this helpful
After taking magnesium, my sleep improved remarkably, as well as my support for cardiovascular disease. It helps alleviate muscle cramps too.
7.5
Cardiovascular support
250 people found this helpful
I appreciate this magnesium as it effectively aids my cardiovascular disease and provides a gentle laxative effect, which benefits my digestion.
7.5
Stress resistance
1 people found this helpful
I chose magnesium citrate for its absorption benefits. It supports muscle, cardiovascular disease, and nervous system health without a laxative effect. Pairing it with B6 enhances its efficacy, which is crucial in today’s dynamic world.
7.5
Energy production aid
1 people found this helpful
After recovering from COVID, I took magnesium to restore my health. It aids in energy production, regulates cardiovascular disease health, fights cramps, and induces relaxation. It's crucial as dietary intake can be insufficient, especially post-medication.
9
Family benefits
51 people found this helpful
My family uses magnesium for various needs; I take it for sleep, my husband for cardiovascular disease, and my son for stress. Magnesium citrate is a staple in our household and its effects are beneficial.
7.5
Calming effect
1 people found this helpful
Magnesium citrate normalises blood pressure and has a calming influence on the muscles and blood vessels, positively impacting cardiovascular disease and sleep disorders.
9
Supports cardiovascular health
2 people found this helpful
Magnesium citrate is readily absorbed and beneficial for overall health. It significantly aids in reducing muscle cramps, promoting digestion, and supporting cardiovascular disease health. For anyone seeking an effective and bioavailable magnesium supplement, this is an excellent option.
7.5
Essential mineral benefits
1 people found this helpful
Magnesium is essential for cellular energy production and regulates blood pressure, with a deficiency raising the risk of cardiovascular disease. I take it in cycles, preferably in the evening, often alongside vitamin B6 for optimal effects.
8
Magnesium linked to cardiovascular health
We examined how magnesium levels in the blood could influence the risk of death from cardiovascular issues in patients with advanced chronic kidney disease (CKD). Our study tracked 1,271 individuals with CKD stages 4 and 5 over a decade, focusing on those who had not previously experienced major heart-related events.

We discovered that higher serum magnesium concentrations were linked to lower risks of dying from conditions like heart failure, coronary heart disease, and stroke. By stratifying patients based on their magnesium levels, we found that those in the highest group experienced significantly better outcomes.

This suggests that maintaining adequate magnesium levels might be important for protecting cardiovascular health in these patients. While it’s just one piece of the puzzle, our findings highlight the potential benefits of magnesium as a factor worth considering in the management of cardiovascular risks.
8
Magnesium's impact on HFpEF mortality
We explored how magnesium supplementation affects mortality rates in patients with heart failure with preserved ejection fraction (HFpEF), a subset of heart failure where treatment options are limited. The study analyzed data from the MIMIC-IV database, focusing on patients from 2008 to 2019. Using a technique called propensity score matching, we aimed to create a balanced comparison between those who received magnesium supplements and those who did not.

Our primary focus was on the 28-day all-cause mortality rate, along with secondary analyses of ICU stays, one-year mortality, and overall hospitalization duration. In total, we evaluated 1,970 patients, splitting them evenly between the magnesium and non-magnesium groups. The outcomes were striking: magnesium intake was associated with a significant reduction in mortality within the first 28 days, particularly benefiting older adults, women, and individuals with hypertension.

While magnesium supplementation showed promise in reducing mortality and also improved longer-term outcomes, we noted that it was linked to longer stays in both ICU and hospital settings. Interestingly, we found that blood urea nitrogen levels may play a role in mediating the relationship between magnesium intake and mortality, suggesting a more complex interaction at play.

This research highlights the potential of magnesium as a valuable treatment for those grappling with HFpEF, especially certain at-risk groups. As we consider these findings, further research is needed to explore magnesium's effects more thoroughly and understand its full implications for patient care.
8
Magnesium impacts blood sugar control
We explored the connections between magnesium (Mg), calcium (Ca), and abnormal levels of HbA1c—a key marker for blood sugar management—in adults with coronary artery disease (CAD). Our research involved a substantial group of 11,934 patients, allowing us to gain valuable insights into how these minerals impact cardiovascular health.

Our findings reveal a noteworthy association: higher serum magnesium levels appear to be linked to lower HbA1c concentrations. Specifically, patients with higher magnesium levels showed a significant decrease in the likelihood of having abnormal HbA1c readings. In contrast, calcium levels did not demonstrate a similar beneficial effect; they were not associated with abnormal HbA1c levels at all.

Interestingly, we also noted that while magnesium correlates with better fasting blood glucose outcomes, higher calcium levels were actually associated with worse results. Additionally, our analysis indicated that inflammation, as gauged by a specific blood marker, didn't mediate the relationship between magnesium and HbA1c. This suggests that magnesium might play a direct role in blood sugar regulation, separate from inflammation's influence.

Overall, our study highlights magnesium's potential importance in managing blood sugar levels among individuals with heart disease, pointing to a promising area for future research and potential dietary considerations.
8
Magnesium's impact on heart health
We examined the connection between dietary magnesium and cardiovascular disease, focusing on how magnesium intake or serum levels relate to heart health. Over the last couple of decades, numerous studies have shown that low magnesium levels are associated with several heart-related issues, including high blood pressure, heart attacks, and even heart failure.

Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.

Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.

References

  1. Yu H, Zhou C, Yang S, Yu J, Zhang X, et al. Mitigation of arteriosclerosis through transcriptional regulation of ferroptosis and lipid metabolism by magnesium. Biomaterials. 2025;319:123135. doi:10.1016/j.biomaterials.2025.123135
  2. Moyano-Peregrin C, Rodelo-Haad C, Martín-Malo A, Muñoz-Castañeda JR, Ojeda R, et al. Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5. Clin Kidney J. 2025;18:sfae390. doi:10.1093/ckj/sfae390
  3. Wang F, Mao Y, Sun J, Yang J, Xiao L, et al. Models based on dietary nutrients predicting all-cause and cardiovascular mortality in people with diabetes. Sci Rep. 2025;15:4600. doi:10.1038/s41598-025-88480-9
  4. Dong H, Lu N, Wang J, Hu P. Serum magnesium, not calcium, is inversely associated with abnormal HbA1c concentrations in adults with coronary artery disease. Asia Pac J Clin Nutr. 2025;34:104. doi:10.6133/apjcn.202502_34(1).0010
  5. Song L, Ying J, Li M, Ying L, Zhao C. Propensity score matched cohort study on magnesium supplementation and mortality in critically ill patients with HFpEF. Sci Rep. 2025;15:1944. doi:10.1038/s41598-025-85931-1
  6. Nielsen FH. The Role of Dietary Magnesium in Cardiovascular Disease. Nutrients. 2024;16. doi:10.3390/nu16234223
  7. Sun L, Du J. Magnesium status, serum vitamin D concentration and mortality among congestive heart failure patients: a cohort study from NHANES 2007-2018. Magnes Res. 2024;37:61. doi:10.1684/mrh.2024.0528
  8. Urbanowicz T, Hanć A, Frąckowiak J, Piecek J, Spasenenko I, et al. The Hypothesis of Trace Elements Involvement in the Coronary Arteries Atherosclerotic Plaques' Location. J Clin Med. 2024;13. doi:10.3390/jcm13226933
  9. Cheng Y, Zullo AR, Yin Y, Shao Y, Liu S, et al. Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation. J Am Heart Assoc. 2025;14:e038870. doi:10.1161/JAHA.124.038870
  10. Shahsavani Z, Masoumi SJ, Barati-Boldaji R, Shamshirgardi E, Kafipour R, et al. Dietary Calcium to Magnesium Ratio and Risk of Cardiovascular Diseases. Biol Trace Elem Res. 2025. doi:10.1007/s12011-025-04587-0
  11. Pariona-Vargas F, Mun KT, Lo EH, Starkman S, Sanossian N, et al. Is there diurnal variation in neuroprotective and thrombolytic therapy effect upon acute cerebral ischemia outcome?. J Stroke Cerebrovasc Dis. 2025;34:108278. doi:10.1016/j.jstrokecerebrovasdis.2025.108278
  12. Amer SA, Abo-Elnour DE, Abbas A, Abdelrahman AS, Hamdy HM, et al. Calcium, magnesium, and vitamin D supplementations as complementary therapy for hypertensive patients: a systematic review and meta-analysis. BMC Complement Med Ther. 2025;25:89. doi:10.1186/s12906-025-04809-x
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