Overview
Top Medical Research Studies
Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
While both groups showed some ECG changes, the magnesium group had fewer overall ischaemic episodes and lower levels of heart enzyme release. Additionally, magnesium seemed to reduce stress hormone levels. Our findings suggest that magnesium can be a valuable treatment option for unstable angina, but more research is needed to confirm its effectiveness.
After identifying 19 patients with insufficient magnesium levels—representing about 8.2% of the group—we treated them with an oral magnesium chloride supplement for five weeks. We were eager to see whether this would help alleviate symptoms, particularly chest pain.
After the treatment period, we observed that magnesium therapy provided statistically significant relief of chest pain for these patients. However, we did not find substantial improvements in other symptoms like palpitations, fatigue, and dyspnea. This finding is vital, as it indicates that while magnesium may play a role in easing chest pain, its overall benefit to other symptoms remains uncertain.
Overall, our study highlights the relatively low prevalence of magnesium deficiency in pediatric patients with mitral valve prolapse compared to adults. Nevertheless, we concluded that magnesium supplementation could be a beneficial approach to address specific symptoms like chest pain in this population.
Most Useful Reviews
Medical Researches
- All Researches
Our exploration revealed that magnesium was indeed part of the treatment plan, but it was combined with potassium and amiloride. This combination makes it challenging to determine how much magnesium alone contributed to alleviating the patient's chest pain.
While magnesium is commonly recognized for its various health benefits, in this specific case, we did not see a clear, isolated benefit from it. Instead, the overall treatment approach seemed to require multiple interventions to achieve improvements in symptoms and biochemical markers.
After identifying 19 patients with insufficient magnesium levels—representing about 8.2% of the group—we treated them with an oral magnesium chloride supplement for five weeks. We were eager to see whether this would help alleviate symptoms, particularly chest pain.
After the treatment period, we observed that magnesium therapy provided statistically significant relief of chest pain for these patients. However, we did not find substantial improvements in other symptoms like palpitations, fatigue, and dyspnea. This finding is vital, as it indicates that while magnesium may play a role in easing chest pain, its overall benefit to other symptoms remains uncertain.
Overall, our study highlights the relatively low prevalence of magnesium deficiency in pediatric patients with mitral valve prolapse compared to adults. Nevertheless, we concluded that magnesium supplementation could be a beneficial approach to address specific symptoms like chest pain in this population.
After a week of treatment, we examined various markers of oxidative stress and monitored cardiac rhythms. The results were promising: potassium magnesium aspartate significantly improved oxidative stress levels and reduced lipid oxidative damage in patients. Notably, there was a marked decrease in the frequency of premature heartbeats in those receiving potassium magnesium aspartate compared to the control group.
It appears that by enhancing oxidative stress status, potassium magnesium aspartate may also contribute to alleviating symptoms associated with arrhythmia, including chest pain. This suggests that oxidative stress could play a critical role in the development of arrhythmias, and addressing it might help treat related symptoms effectively.
Our findings revealed that those who took magnesium experienced improved exercise tolerance and better left ventricular function during both rest and exercise. Importantly, magnesium appeared to help reduce exercise-induced chest pain, which is often a concern for those with CAD.
By observing changes in maximal oxygen uptake and heart performance curves, we gained valuable insights into the potential benefits of magnesium therapy. The study highlights a promising option for those dealing with the challenges of CAD, particularly in managing discomfort during physical activity.
Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
User Reviews
- All Reviews
- Positive Reviews
- Negative Reviews
Frequently Asked Questions
Chest pain is a broad term that refers to discomfort or pain felt in the chest area, and it can arise from a variety of causes. It can range from a sharp, stabbing sensation to a dull ache or pressure. Some common causes of chest pain include heart-related issues, such as angina or heart attacks, as well as non-cardiac conditions like acid reflux, musculoskeletal problems, or anxiety. Since chest pain can represent a serious condition, especially if it is sudden and severe, it's crucial to pay attention to accompanying symptoms such as shortness of breath, sweating, or nausea, which may warrant immediate medical attention.
If you're experiencing chest pain, it's essential to consult a healthcare professional for an accurate diagnosis. They may perform tests such as an electrocardiogram (ECG), blood tests, or imaging studies to determine the underlying cause. Early identification of heart-related issues can be life-saving, while non-cardiac causes, though often less serious, still require appropriate assessment and treatment. Understanding the context and quality of the pain can help guide that conversation with your doctor, ensuring you receive the best care possible.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Based on user reviews, the time it takes to see results from magnesium supplementation can vary significantly from person to person. Users have reported experiencing relief from issues such as joint pain, headaches, and muscle cramps relatively quickly, often within days to weeks of starting the supplement. For example, one reviewer noted that after using higher doses of magnesium, the cramps and menstrual pain disappeared entirely ((Read Review)). Another user found substantial improvement in their knee pain, allowing for easier navigation of stairs after incorporating magnesium into their routine ((Read Review)).
However, it's important to note that individual results may depend on various factors, including the severity of symptoms and the specific magnesium formulation used. While some users reported noticing improvements very quickly, others might require a longer duration for noticeable effects. Listening to your body and consulting with a healthcare professional for personalized advice is recommended for the best outcomes.
Magnesium supplementation has been the focus of several studies examining its potential to relieve chest pain associated with various conditions, particularly coronary artery disease and angina. For instance, one study involving patients with stable coronary artery disease found that magnesium intake helped decrease exercise-induced chest pain and improve overall exercise tolerance, suggesting that magnesium could be beneficial for those grappling with chest discomfort during physical activity [5]. However, it's worth noting that magnesium's effectiveness can vary by population and health condition.
Despite some promising findings, the overall conclusion across multiple studies indicates that while magnesium may help in specific cases—such as its role in pediatric patients with mitral valve prolapse, where significant relief from chest pain was observed [3]—its effectiveness as a panacea for chest pain remains doubtful. For example, research evaluating magnesium's effect on patients with acute myocardial infarction showed no substantial improvements in chest pain or mortality rates [18]. Thus, while there is some evidence supporting the beneficial role of magnesium in certain contexts, the overall consensus suggests that it may not be a comprehensive solution for chest pain relief.
Based on user reviews, many individuals report a significant improvement in various symptoms after incorporating magnesium into their daily routines. Users highlighted changes such as a considerable reduction in knee pain, which allowed one reviewer to navigate stairs without discomfort ((Read Review)). Additionally, magnesium was noted to alleviate headaches and menstrual discomfort, with one user experiencing total relief from these issues after increasing their magnesium intake ((Read Review)). Similarly, another reviewer mentioned that magnesium citrate effectively mitigated muscle tension after intense workouts, leading to a pain-free experience the following day ((Read Review)).
Moreover, users with a history of magnesium deficiency reported positive transformations, with one individual witnessing a drastic reduction in joint pain and improved sleep quality after starting supplementation ((Read Review)). It's worth noting that while some have experienced quick relief from symptoms, the degree of improvement can vary greatly among individuals. Overall, magnesium appears to be a valuable ally for those seeking relief from pain and discomfort, but personal results may differ. Users are encouraged to seek tailored guidance from healthcare professionals for an optimal approach to their symptoms.
Users have reported various experiences when combining magnesium supplements with other products in their regimen. One reviewer noted significant improvements in knee pain after using magnesium alongside omega-3 and collagen supplements, indicating a synergistic effect that contributed to their recovery and ongoing mobility improvements ((Read Review)). This suggests that users may find enhanced relief from symptoms when integrating magnesium with other dietary aids.
Additionally, another user highlighted the effectiveness of magnesium citrate for alleviating headaches and muscle tension primarily after workouts, implying that it works effectively on its own but can be part of a broader supplement routine ((Read Review)). While the specific combinations with other supplements weren't extensively detailed in user reviews, the overall sentiment leans towards magnesium being a versatile and beneficial addition to various health routines. Overall, users are encouraged to explore different combinations to find what works best for their unique needs.
Our findings revealed that those who took magnesium experienced improved exercise tolerance and better left ventricular function during both rest and exercise. Importantly, magnesium appeared to help reduce exercise-induced chest pain, which is often a concern for those with CAD.
By observing changes in maximal oxygen uptake and heart performance curves, we gained valuable insights into the potential benefits of magnesium therapy. The study highlights a promising option for those dealing with the challenges of CAD, particularly in managing discomfort during physical activity.
After identifying 19 patients with insufficient magnesium levels—representing about 8.2% of the group—we treated them with an oral magnesium chloride supplement for five weeks. We were eager to see whether this would help alleviate symptoms, particularly chest pain.
After the treatment period, we observed that magnesium therapy provided statistically significant relief of chest pain for these patients. However, we did not find substantial improvements in other symptoms like palpitations, fatigue, and dyspnea. This finding is vital, as it indicates that while magnesium may play a role in easing chest pain, its overall benefit to other symptoms remains uncertain.
Overall, our study highlights the relatively low prevalence of magnesium deficiency in pediatric patients with mitral valve prolapse compared to adults. Nevertheless, we concluded that magnesium supplementation could be a beneficial approach to address specific symptoms like chest pain in this population.
Despite increased serum magnesium levels, we found no significant impact on in-hospital or long-term mortality rates between the two groups. Notably, the magnesium group experienced a higher incidence of heart rhythm issues. Overall, our findings indicate that magnesium does not provide meaningful benefits for treating acute ischemic heart syndromes.
References
- Ola O, Gharacholou SM, Del-Carpio Munoz F. Massive Discordant T-Wave Alternans and Imminent Torsades de Pointes: The "Elephant in the Room". JAMA Intern Med. 2021;181:1393. doi:10.1001/jamainternmed.2021.4021
- Poudel A. An adolescent with tingling and numbness of hand: gitelman syndrome. N Am J Med Sci. 2015;7:27. doi:10.4103/1947-2714.150086
- Amoozgar H, Rafizadeh H, Ajami G, Borzoee M. The prevalence of hypomagnesaemia in pediatric patients with mitral valve prolapse syndrome and the effect of mg therapy. Int Cardiovasc Res J. 2012;6:92.
- Zhi YF, Huang YS, Xu BS, Wang SR. [Clinical investigation of the protective effects of potassium magnesium aspartate against arrhythmia and its possible anti-oxidative mechanism]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2007;19:662.
- Pokan R, Hofmann P, von Duvillard SP, Smekal G, Wonisch M, et al. Oral magnesium therapy, exercise heart rate, exercise tolerance, and myocardial function in coronary artery disease patients. Br J Sports Med. 2006;40:773.
- Sovová E, Skvarilová M, Bartousek J, Doupal V, Lukl J, et al. [Latent tetany in patients with a negative coronarographic finding]. Vnitr Lek. 1999;45:291.
- Guo H, Cheng J, Lee JD, Ueda T, Shan J, et al. Relationship between the degree of intracellular magnesium deficiency and the frequency of chest pain in women with variant angina. Herz. 2004;29:299.
- Shechter M, Bairey Merz CN, Stuehlinger HG, Slany J, Pachinger O, et al. Effects of oral magnesium therapy on exercise tolerance, exercise-induced chest pain, and quality of life in patients with coronary artery disease. Am J Cardiol. 2003;91:517.
- Ezhov AV, Pimenov LT. [Effect of adjuvant magnesium therapy on the quality of life and emotional status of elderly patients with stable angina]. Adv Gerontol. 2002;10:95.
- Teragawa H, Kato M, Yamagata T, Matsuura H, Kajiyama G. The preventive effect of magnesium on coronary spasm in patients with vasospastic angina. Chest. 2000;118:1690.
- Sueda S, Saeki H, Otani T, Mineoi K, Kondo T, et al. Limited efficacy of magnesium for the treatment of variant angina. J Cardiol. 1999;34:139.
- Shibata M, Ueshima K, Harada M, Nakamura M, Hiramori K, et al. Effect of magnesium sulfate pretreatment and significance of matrix metalloproteinase-1 and interleukin-6 levels in coronary reperfusion therapy for patients with acute myocardial infarction. Angiology. 1999;50:573.
- Redwood SR, Bashir Y, Huang J, Leatham EW, Kaski JC, et al. Effect of magnesium sulphate in patients with unstable angina. A double blind, randomized, placebo-controlled study. Eur Heart J. 1997;18:1269.
- Satake K, Lee JD, Shimizu H, Ueda T, Nakamura T. Relation between severity of magnesium deficiency and frequency of anginal attacks in men with variant angina. J Am Coll Cardiol. 1996;28:897.
- Gawaz M, Reininger A, Neumann FJ. Platelet function and platelet-leukocyte adhesion in symptomatic coronary heart disease. Effects of intravenous magnesium. Thromb Res. 1996;83:341.
- Otani H, Kawasaki H, Ninomiya H, Kido M, Kawaguchi H. [Significance of hot shot in patients with unstable angina undergoing emergency coronary artery bypass graft surgery]. Nihon Kyobu Geka Gakkai Zasshi. 1996;44:123.
- Caspi J, Rudis E, Bar I, Safadi T, Saute M. Effects of magnesium on myocardial function after coronary artery bypass grafting. Ann Thorac Surg. 1995;59:942.
- Feldstedt M, Boesgaard S, Bouchelouche P, Svenningsen A, Brooks L, et al. Magnesium substitution in acute ischaemic heart syndromes. Eur Heart J. 1991;12:1215.
- Tanabe K, Noda K, Mikawa T, Murayama M, Sugai J. Magnesium content of erythrocytes in patients with vasospastic angina. Cardiovasc Drugs Ther. 1991;5:677.
