We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
Most Useful Reviews
9
Better sleep
23 people found this helpful
I struggled with chronic fatigue syndrome, often waking multiple times at night. However, after starting magnesium on my doctor’s advice, I now fall asleep quickly and wake refreshed. It also positively affects my cardiovascular system and helps with muscle cramps. Highly recommend it!
Read More
9
Calmer feelings
14 people found this helpful
I've realised I'm magnesium deficient, impacting my chronic fatigue syndrome. The symptoms of irritability, poor sleep and chronic fatigue have improved significantly with its use. I've chosen a soluble form, which works best for me, lifting my mood and improving my calmness and sleep quality.
Read More
9
Constipation relief
12 people found this helpful
I sought magnesium for my mother's constipation, which persistent laxatives failed to resolve. After switching to a better-absorbed magnesium, her chronic fatigue syndrome improved significantly, leading to relief from years of suffering. It truly does wonders for those experiencing such issues!
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.
Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
Read More
4
Limited magnesium effectiveness in CFS
Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review.
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).
Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.
While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.
Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 76 Reviews
7.9
All Reviews
Positive Reviews
Negative Reviews
9
Better sleep
23 people found this helpful
I struggled with chronic fatigue syndrome, often waking multiple times at night. However, after starting magnesium on my doctor’s advice, I now fall asleep quickly and wake refreshed. It also positively affects my cardiovascular system and helps with muscle cramps. Highly recommend it!
Read More
9
Calmer feelings
14 people found this helpful
I've realised I'm magnesium deficient, impacting my chronic fatigue syndrome. The symptoms of irritability, poor sleep and chronic fatigue have improved significantly with its use. I've chosen a soluble form, which works best for me, lifting my mood and improving my calmness and sleep quality.
Read More
9
Constipation relief
12 people found this helpful
I sought magnesium for my mother's constipation, which persistent laxatives failed to resolve. After switching to a better-absorbed magnesium, her chronic fatigue syndrome improved significantly, leading to relief from years of suffering. It truly does wonders for those experiencing such issues!
Read More
9
Symptoms alleviated
12 people found this helpful
Best magnesium! I started taking it due to muscle cramps in my calves and experiencing heart palpitations, increased irritability, mood swings, and chronic fatigue syndrome. After taking one tablet in the morning, I experienced significant relief and no side effects. I recommend it to everyone!
Read More
9
Calmness achieved
7 people found this helpful
I was prescribed magnesium after recovering from Covid. After two months of taking this citrate form, I noticed significant improvements. Previously, I had chronic fatigue syndrome and irritability, but I now feel calmer and suffer fewer night cramps. Highly recommend!
Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a complex and debilitating condition characterized by profound fatigue that doesn’t improve with rest and worsens with physical or mental activity. This crippling fatigue is often accompanied by a variety of symptoms, including sleep disturbances, cognitive difficulties, muscle pain, and joint pain. Unlike typical tiredness, the fatigue experienced in CFS is long-lasting, and it can significantly hinder everyday activities and overall quality of life.
The precise cause of CFS remains unknown, but it is believed to be influenced by a combination of genetic, environmental, immunological, and psychological factors. Diagnosis primarily relies on a careful assessment of symptoms, as there are no definitive laboratory tests available. Treatment options focus on symptom management and may include lifestyle changes, physical therapy, medication for pain management, and cognitive behavioral therapy. Given the complexity and variability of the condition, individuals with CFS should consult healthcare professionals who specialize in this area to develop personalized management strategies.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
While there is ongoing research into the potential benefits of magnesium for various health conditions, including Chronic Fatigue Syndrome (CFS), definitive conclusions remain elusive. Magnesium plays a critical role in energy production, muscle function, and overall metabolism, which suggests it may provide some support for those suffering from CFS. Some anecdotal evidence and small-scale studies suggest that magnesium supplementation could help alleviate certain symptoms associated with fatigue, particularly if a deficiency is present. However, further extensive clinical studies are needed to establish a clear link between magnesium supplementation and improvement in CFS symptoms.
It's important for individuals considering magnesium supplementation to consult with a healthcare professional. They can determine individual needs and whether magnesium may be beneficial based on personal health profiles and existing conditions. Additionally, magnesium should not be viewed as a standalone solution for Chronic Fatigue Syndrome; a comprehensive approach that includes lifestyle changes, a balanced diet, and other treatments may be necessary for managing symptoms effectively.
Based on user reviews, individuals taking magnesium supplements for Chronic Fatigue Syndrome (CFS) typically report experiencing improvements in their symptoms within a timeframe that varies from a few days to a couple of months. For instance, one user noted significant relief from fatigue after just a few days of use, feeling less lethargic and more energetic (Read Review). Another user indicated improvements within two months after starting a particular magnesium citrate form, leading to enhanced mood and better sleep quality (Read Review).
The effectiveness of magnesium seems to depend on the form of the supplement and individual response times. Some users have reported significant symptom relief from chronic fatigue syndrome after a relatively short duration, such as one week, while others required a longer process of consistent use to achieve desired results (Read Review). This variability highlights the importance of patience and consistency when incorporating magnesium as part of a regimen for combating the symptoms of CFS.
While the potential benefits of magnesium supplementation for Chronic Fatigue Syndrome (CFS) are garnering attention, the scientific research is still mixed. A systematic review of multiple studies on complementary and alternative medicine for CFS indicated limited overall effectiveness, although magnesium was noted to have some potential (see [1]). Another research piece highlighted that a significant number of patients exhibited magnesium deficiency, but magnesium supplementation did not lead to remarkable improvements in fatigue or oxidative stress parameters (see [2]).
However, some individual studies have reported positive outcomes, such as a notable case study where magnesium sulfate treatment led to substantial improvements in fatigue and daily functioning in a patient with severe CFS (see [3]). Furthermore, a randomized controlled trial showed that patients treated with magnesium sulfate experienced significant enhancements in energy and overall wellbeing compared to those receiving a placebo (see [5]). Despite these promising results, it is clear that more rigorous and larger-scale studies are necessary to validate the effectiveness of magnesium as a treatment for CFS definitively.
Based on user reviews, many individuals report significant improvements in their Chronic Fatigue Syndrome (CFS) symptoms after incorporating magnesium into their routines. Users have mentioned experiencing enhanced sleep quality, with one reviewer noting they now fall asleep quickly and wake up refreshed (Read Review). Another shared that after two months of taking magnesium citrate, they felt calmer and more energetic, also highlighting not waking up with night cramps (Read Review). The lifting of irritability and muscle tension was another commonly reported benefit, with one user stating improvements in mood and reduced fatigue within just one week of use (Read Review).
It’s clear that users experience varying levels of relief, and while some notice changes within a few days, others report more gradual improvements over weeks or months. For instance, one reviewer detailed a three-year journey using magnesium, with significant reduction in symptoms over that time frame (Read Review). This highlights that while magnesium may be beneficial for many, individual results can certainly vary based on factors such as dosage, form of magnesium used, and personal health conditions.
Based on user reviews, many individuals managing Chronic Fatigue Syndrome (CFS) have reported positive experiences when combining magnesium supplements with other supplements. For example, one user noted that taking magnesium alongside calcium enhanced their muscle relaxation and improved sleep quality, allowing them to wake up feeling refreshed and in a better mood (Read Review). This suggests that pairing magnesium with calcium may create a synergistic effect that benefits sleep and overall well-being, which is crucial for those struggling with the symptoms of CFS.
Moreover, users have expressed that magnesium, particularly in forms like citrate and chelate, plays a significant role in alleviating fatigue and other related symptoms. One review indicated the transformation in fatigue levels after a consistent intake of such magnesium forms, further emphasizing its effectiveness when integrated into a broader supplement regimen (Read Review, Read Review). The combination of magnesium with other supportive supplements appears to enhance the overall management of CFS, leading to improved sleep, reduced anxiety, and increased energy levels, highlighting the importance of a comprehensive approach to treatment for this condition.
Based on user reviews, many individuals have found magnesium to be beneficial for managing symptoms of Chronic Fatigue Syndrome (CFS), though specific dosing recommendations vary. Some users report significant improvements in their fatigue and sleep quality after regularly taking magnesium in different forms, notably magnesium citrate. For instance, one reviewer mentioned taking 400 mg daily, which notably reduced their fatigue symptoms and helped ease stress and insomnia issues Read Review. Others have highlighted that taking magnesium before bed has enhanced their sleep and relaxation, suggesting timing may play a role in its efficacy Read Review.
Users also noted improvements in overall mood and irritability, with one individual reporting relief from symptoms after a couple of weeks on a magnesium citrate supplement Read Review. The general consensus among reviewers is that magnesium, especially in well-absorbed forms like citrate, can provide relief for CFS symptoms, but the ideal dose may depend on individual needs and responses, as reflected in various experiences shared by users.
9
Fatigue relief noted
2 people found this helpful
I can genuinely feel the difference in fatigue relief while using magnesium. After just a few days, I realised I wasn't dragging through the days as I had been before.
9
Calmness achieved
7 people found this helpful
I was prescribed magnesium after recovering from Covid. After two months of taking this citrate form, I noticed significant improvements. Previously, I had chronic fatigue syndrome and irritability, but I now feel calmer and suffer fewer night cramps. Highly recommend!
9
Supports sleep quality
This magnesium is excellent for replenishing minerals. It has improved my sleep, alleviated fatigue and depression, and helped with muscle cramps. I've noticed results within a week!
9
Better sleep
23 people found this helpful
I struggled with chronic fatigue syndrome, often waking multiple times at night. However, after starting magnesium on my doctor’s advice, I now fall asleep quickly and wake refreshed. It also positively affects my cardiovascular system and helps with muscle cramps. Highly recommend it!
10
Coping with fatigue
This magnesium supplement helps relieve anxiety and muscle tension. It’s difficult to obtain enough magnesium from food alone. After two years, my chronic fatigue syndrome has improved significantly, and I feel more balanced.
9
Improved morning mood
2 people found this helpful
I take magnesium before bed, which has improved both my muscle relaxation and sleep quality. I used to wake up completely drained, but since I started taking magnesium and calcium nightly, I wake up refreshed and in a good mood. My mother also benefits from this routine for her sleep issues.
9
Improves life quality
1 people found this helpful
This performance supplement has transformed my life. It alleviated my chronic fatigue syndrome, headaches, and anxiety. I've discovered that magnesium deficiency can cause many symptoms. I've found that magnesium chelates and citrate are well-absorbed, unlike poorer forms. After two years of use, I’ve become more balanced and energetic.
9
Improved mood
I have been consistently using this magnesium citrate. It’s well absorbed, enhances energy, alleviates fatigue, and improves sleep and mood. It has helped manage symptoms of chronic fatigue syndrome effectively.
7.5
Improved calmness
718 people found this helpful
Calm, just calm. After taking 400 mg of magnesium daily for a few weeks, my symptoms of chronic fatigue syndrome improved significantly. Magnesium helped ease my stress and enhance my sleep. While insomnia persists occasionally, twitches that once woke me have diminished. I believe magnesium has enabled me to manage stress better and attain a sense of calm.
4
Limited magnesium effectiveness in CFS
Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review.
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).
Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.
While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.
Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
8
Magnesium potentially benefits CFS patients
Red blood cell magnesium and chronic fatigue syndrome.
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
References
Alraek T, Lee MS, Choi TY, Cao H, Liu J. Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review. BMC Complement Altern Med. 2011;11:87. doi:10.1186/1472-6882-11-87
Manuel y Keenoy B, Moorkens G, Vertommen J, Noe M, Nève J, et al. Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium. J Am Coll Nutr. 2000;19:374.
Takahashi H, Imai K, Katanuma A, Sugaya T, Hisano K, et al. [A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate]. Arerugi. 1992;41:1605.
Uchida A. [Therapy of chronic fatigue syndrome]. Nihon Rinsho. 1992;50:2679.
Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991;337:757.