Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.6
USERS' SCORE
Medium or Average
Based on 53 Reviews
6.3
Supplement Facts
Serving Size: 3 Veg Capsules
Amount Per Serving
%DV
Magnesium (elemental) (from 2,667 mg Magnesium Citrate)
400 mg
95%
Top Medical Research Studies
9.5
We explored the impact of magnesium on secretory diarrhea, particularly in the context of cholera, a significant global health issue. The focus was on understanding how magnesium, often overlooked, could serve as an effective treatment option. In our study, we found that increasing levels of magnesium can significantly inhibit chloride secretion in intestinal cells, which is crucial during episodes of diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
8
We investigated the relationship between magnesium treatment and diarrhea in patients with HNF1B syndrome, where we found that hypomagnesemia is quite common.
A notable case involved a patient with a de novo heterozygous deletion of the HNF1B gene, who suffered from severe diarrhea due to low magnesium levels. After receiving magnesium supplementation, the patient's diarrhea symptoms improved significantly.
Our findings indicate that those with HNF1B deletion are more likely to experience low magnesium levels compared to individuals with intragenic mutations. In fact, among a large group of patients with HNF1B syndrome, over half experienced hypomagnesemia.
This suggests a strong connection between magnesium deficiency and the gastrointestinal issues seen in this condition. It highlights the importance of monitoring magnesium levels in patients, as addressing this deficiency can lead to meaningful relief from diarrhea symptoms.
A notable case involved a patient with a de novo heterozygous deletion of the HNF1B gene, who suffered from severe diarrhea due to low magnesium levels. After receiving magnesium supplementation, the patient's diarrhea symptoms improved significantly.
Our findings indicate that those with HNF1B deletion are more likely to experience low magnesium levels compared to individuals with intragenic mutations. In fact, among a large group of patients with HNF1B syndrome, over half experienced hypomagnesemia.
This suggests a strong connection between magnesium deficiency and the gastrointestinal issues seen in this condition. It highlights the importance of monitoring magnesium levels in patients, as addressing this deficiency can lead to meaningful relief from diarrhea symptoms.
9
We observed a fascinating case involving a 70-day-old baby girl from Iran who was suffering from severe hypomagnesemia and secondary hypocalcemia. She exhibited signs like seizures and persistent watery diarrhea shortly after birth, leading to significant health challenges, including failure to thrive.
In her treatment, both magnesium and calcium supplementation were used. Despite an initial struggle with response to the magnesium, we noted that over time, her condition improved, and the diarrhea subsided. This suggests that magnesium might play a crucial role in managing diarrhea, especially in cases related to deficiencies.
Additionally, a genetic analysis revealed a novel alteration in her TRPM6 gene, which is notable because such variants are linked to magnesium transport issues. This connection highlights the importance of magnesium not only in treating diarrhea but also in the overall well-being of individuals with genetic predispositions affecting magnesium levels.
Our follow-up with the patient over two years showed no relapses, indicating a positive response to the treatment plan incorporating magnesium. While our findings centered on this specific instance, they contribute to a broader understanding of magnesium's therapeutic effects on diarrhea and related health problems.
In her treatment, both magnesium and calcium supplementation were used. Despite an initial struggle with response to the magnesium, we noted that over time, her condition improved, and the diarrhea subsided. This suggests that magnesium might play a crucial role in managing diarrhea, especially in cases related to deficiencies.
Additionally, a genetic analysis revealed a novel alteration in her TRPM6 gene, which is notable because such variants are linked to magnesium transport issues. This connection highlights the importance of magnesium not only in treating diarrhea but also in the overall well-being of individuals with genetic predispositions affecting magnesium levels.
Our follow-up with the patient over two years showed no relapses, indicating a positive response to the treatment plan incorporating magnesium. While our findings centered on this specific instance, they contribute to a broader understanding of magnesium's therapeutic effects on diarrhea and related health problems.
Most Useful Reviews
9
Reduced diarrhea
40 people found this helpful
Very nice mineral! I found that my legs drank in the middle of the night, and they felt lighter. My heart feels better, and I move more easily. Surprisingly, magnesium citrate is easy to absorb and doesn’t cause diarrhea.
9
Safe laxative
5 people found this helpful
Magnesium citrate has optimal absorption and acts as a safe laxative. It’s essential for cleansing the intestines and is effective when taken after meals to avoid irritation or diarrhoea especially for those with sensitive stomachs.
9
Relieves constipation
4 people found this helpful
Since taking magnesium, I no longer suffer from alternating constipation and diarrhoea. I had no idea how deficient I was in magnesium, but it has truly helped me feel better.
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.6
- All Researches
9.5
We explored the impact of magnesium on secretory diarrhea, particularly in the context of cholera, a significant global health issue. The focus was on understanding how magnesium, often overlooked, could serve as an effective treatment option. In our study, we found that increasing levels of magnesium can significantly inhibit chloride secretion in intestinal cells, which is crucial during episodes of diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
9
We observed a fascinating case involving a 70-day-old baby girl from Iran who was suffering from severe hypomagnesemia and secondary hypocalcemia. She exhibited signs like seizures and persistent watery diarrhea shortly after birth, leading to significant health challenges, including failure to thrive.
In her treatment, both magnesium and calcium supplementation were used. Despite an initial struggle with response to the magnesium, we noted that over time, her condition improved, and the diarrhea subsided. This suggests that magnesium might play a crucial role in managing diarrhea, especially in cases related to deficiencies.
Additionally, a genetic analysis revealed a novel alteration in her TRPM6 gene, which is notable because such variants are linked to magnesium transport issues. This connection highlights the importance of magnesium not only in treating diarrhea but also in the overall well-being of individuals with genetic predispositions affecting magnesium levels.
Our follow-up with the patient over two years showed no relapses, indicating a positive response to the treatment plan incorporating magnesium. While our findings centered on this specific instance, they contribute to a broader understanding of magnesium's therapeutic effects on diarrhea and related health problems.
In her treatment, both magnesium and calcium supplementation were used. Despite an initial struggle with response to the magnesium, we noted that over time, her condition improved, and the diarrhea subsided. This suggests that magnesium might play a crucial role in managing diarrhea, especially in cases related to deficiencies.
Additionally, a genetic analysis revealed a novel alteration in her TRPM6 gene, which is notable because such variants are linked to magnesium transport issues. This connection highlights the importance of magnesium not only in treating diarrhea but also in the overall well-being of individuals with genetic predispositions affecting magnesium levels.
Our follow-up with the patient over two years showed no relapses, indicating a positive response to the treatment plan incorporating magnesium. While our findings centered on this specific instance, they contribute to a broader understanding of magnesium's therapeutic effects on diarrhea and related health problems.
9
In our exploration of how potassium-magnesium sulfate (PMS) impacts diarrhea in weaned piglets, we set out to understand its effects on growth performance, immunity, and gut health. A total of 216 piglets were divided into six groups, with varying levels of PMS in their diets.
Our findings revealed some compelling results: the addition of PMS significantly reduced the diarrhea rate among the piglets. Notably, when we included 0.3% PMS in their diet, we observed improved antioxidant capacity, which plays a crucial role in maintaining overall gut health.
We also discovered that PMS supplementation positively influenced intestinal immunity by lowering certain inflammatory markers, further suggesting its beneficial role in digestive health. Additionally, the changes in gut bacteria composition indicated that magnesium may help foster a healthier gut environment.
Overall, our study sheds light on magnesium's potential role as a treatment option for reducing diarrhea in weaned piglets, emphasizing its effectiveness in fostering both immunity and gut health.
Our findings revealed some compelling results: the addition of PMS significantly reduced the diarrhea rate among the piglets. Notably, when we included 0.3% PMS in their diet, we observed improved antioxidant capacity, which plays a crucial role in maintaining overall gut health.
We also discovered that PMS supplementation positively influenced intestinal immunity by lowering certain inflammatory markers, further suggesting its beneficial role in digestive health. Additionally, the changes in gut bacteria composition indicated that magnesium may help foster a healthier gut environment.
Overall, our study sheds light on magnesium's potential role as a treatment option for reducing diarrhea in weaned piglets, emphasizing its effectiveness in fostering both immunity and gut health.
9
We conducted a study to assess the effectiveness of magnesium in treating diarrhea, particularly focusing on its role in extracts from (Wall.) leaves. To evaluate this, we utilized several tests that mimic diarrhea conditions. Our findings showed that while magnesium was mentioned in connection with the extracts, it was administered alongside other treatments. This means we're not entirely sure how much of the anti-diarrheal effect was due to magnesium itself.
In our tests, the methanol extract of (Wall.) leaves was particularly noteworthy, showing significant inhibition of diarrhea at a dose of 400 mg/kg. However, the role of magnesium in this context remains ambiguous since it wasn't given alone. In essence, while the extract worked well against diarrhea, the individual contribution of magnesium to this benefit is unclear.
Overall, we support the traditional use of (Wall.) plants in managing diarrhea and pain, but we need more focused research to isolate the effects of magnesium.
In our tests, the methanol extract of (Wall.) leaves was particularly noteworthy, showing significant inhibition of diarrhea at a dose of 400 mg/kg. However, the role of magnesium in this context remains ambiguous since it wasn't given alone. In essence, while the extract worked well against diarrhea, the individual contribution of magnesium to this benefit is unclear.
Overall, we support the traditional use of (Wall.) plants in managing diarrhea and pain, but we need more focused research to isolate the effects of magnesium.
8
We investigated the relationship between magnesium treatment and diarrhea in patients with HNF1B syndrome, where we found that hypomagnesemia is quite common.
A notable case involved a patient with a de novo heterozygous deletion of the HNF1B gene, who suffered from severe diarrhea due to low magnesium levels. After receiving magnesium supplementation, the patient's diarrhea symptoms improved significantly.
Our findings indicate that those with HNF1B deletion are more likely to experience low magnesium levels compared to individuals with intragenic mutations. In fact, among a large group of patients with HNF1B syndrome, over half experienced hypomagnesemia.
This suggests a strong connection between magnesium deficiency and the gastrointestinal issues seen in this condition. It highlights the importance of monitoring magnesium levels in patients, as addressing this deficiency can lead to meaningful relief from diarrhea symptoms.
A notable case involved a patient with a de novo heterozygous deletion of the HNF1B gene, who suffered from severe diarrhea due to low magnesium levels. After receiving magnesium supplementation, the patient's diarrhea symptoms improved significantly.
Our findings indicate that those with HNF1B deletion are more likely to experience low magnesium levels compared to individuals with intragenic mutations. In fact, among a large group of patients with HNF1B syndrome, over half experienced hypomagnesemia.
This suggests a strong connection between magnesium deficiency and the gastrointestinal issues seen in this condition. It highlights the importance of monitoring magnesium levels in patients, as addressing this deficiency can lead to meaningful relief from diarrhea symptoms.
User Reviews
USERS' SCORE
Medium or Average
Based on 53 Reviews
6.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reduced diarrhea
40 people found this helpful
Very nice mineral! I found that my legs drank in the middle of the night, and they felt lighter. My heart feels better, and I move more easily. Surprisingly, magnesium citrate is easy to absorb and doesn’t cause diarrhea.
9
Safe laxative
5 people found this helpful
Magnesium citrate has optimal absorption and acts as a safe laxative. It’s essential for cleansing the intestines and is effective when taken after meals to avoid irritation or diarrhoea especially for those with sensitive stomachs.
9
Relieves constipation
4 people found this helpful
Since taking magnesium, I no longer suffer from alternating constipation and diarrhoea. I had no idea how deficient I was in magnesium, but it has truly helped me feel better.
0
Diarrhea comparison
3 people found this helpful
Not bad, but Thorne Research Magnesium Citramate is better. The latter does not cause diarrhoea, unlike this product, although I didn’t feel much effect from either.
9
Natural laxative effect
1 people found this helpful
Very effective for constipation; it’s a natural laxative that cleans the digestive system without causing diarrhoea. I take three pills daily as instructed, and it has truly helped me.
Frequently Asked Questions
0
Severe diarrhea
1 people found this helpful
After following the recommended dosage, I had severe diarrhoea. I intend to find a suitable intake for my body.
0
Severe diarrhoea
1 people found this helpful
I had terrible diarrhoea after taking magnesium citrate for two weeks. It resulted in continuous watery diarrhoea, indicating it might not suit everyone.
9
Relieves constipation
4 people found this helpful
Since taking magnesium, I no longer suffer from alternating constipation and diarrhoea. I had no idea how deficient I was in magnesium, but it has truly helped me feel better.
0
Strong diarrhoea
This form was very strong and even with half the dosage, it caused severe stomach aches and diarrhoea. I would not recommend it.
0
Diarrhea occurrence
It didn't fit, and it caused me diarrhoea. It simply did not suit me, which is unfortunate.
2
Eases constipation
16 people found this helpful
This magnesium form has minor effects but is essential as many people are deficient. I appreciate its easy absorption and its benefits in relieving ailments like constipation and heartburn. However, large doses can lead to diarrhoea.
9
Natural laxative effect
1 people found this helpful
Very effective for constipation; it’s a natural laxative that cleans the digestive system without causing diarrhoea. I take three pills daily as instructed, and it has truly helped me.
0
Cramps and diarrhea
1 people found this helpful
I experienced severe cramps and diarrhoea, though it seems to work for my husband.
0
Combining forms
1 people found this helpful
I have been using it for a while but combine it with other forms of magnesium because it causes diarrhoea.
9
Safe laxative
5 people found this helpful
Magnesium citrate has optimal absorption and acts as a safe laxative. It’s essential for cleansing the intestines and is effective when taken after meals to avoid irritation or diarrhoea especially for those with sensitive stomachs.
0
Diarrhoea side effect
This magnesium form is good, but unfortunately it caused me diarrhoea. I decided to switch to a milder form, glycinate, to avoid this issue.
0
Dose caution
Good magnesium in citrate form, but one must remember that it can cause diarrhoea. It’s important to calculate the dose correctly.
9.5
We explored the impact of magnesium on secretory diarrhea, particularly in the context of cholera, a significant global health issue. The focus was on understanding how magnesium, often overlooked, could serve as an effective treatment option. In our study, we found that increasing levels of magnesium can significantly inhibit chloride secretion in intestinal cells, which is crucial during episodes of diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
8
We investigated the relationship between magnesium treatment and diarrhea in patients with HNF1B syndrome, where we found that hypomagnesemia is quite common.
A notable case involved a patient with a de novo heterozygous deletion of the HNF1B gene, who suffered from severe diarrhea due to low magnesium levels. After receiving magnesium supplementation, the patient's diarrhea symptoms improved significantly.
Our findings indicate that those with HNF1B deletion are more likely to experience low magnesium levels compared to individuals with intragenic mutations. In fact, among a large group of patients with HNF1B syndrome, over half experienced hypomagnesemia.
This suggests a strong connection between magnesium deficiency and the gastrointestinal issues seen in this condition. It highlights the importance of monitoring magnesium levels in patients, as addressing this deficiency can lead to meaningful relief from diarrhea symptoms.
A notable case involved a patient with a de novo heterozygous deletion of the HNF1B gene, who suffered from severe diarrhea due to low magnesium levels. After receiving magnesium supplementation, the patient's diarrhea symptoms improved significantly.
Our findings indicate that those with HNF1B deletion are more likely to experience low magnesium levels compared to individuals with intragenic mutations. In fact, among a large group of patients with HNF1B syndrome, over half experienced hypomagnesemia.
This suggests a strong connection between magnesium deficiency and the gastrointestinal issues seen in this condition. It highlights the importance of monitoring magnesium levels in patients, as addressing this deficiency can lead to meaningful relief from diarrhea symptoms.
5
We investigated the effects of naldemedine, a medication often used to treat opioid-induced constipation, in combination with magnesium oxide (MgO) and other laxatives during hospital stays. Our study focused on how these treatments affected daily bowel movements and the occurrence of diarrhea.
Analysis of 93 inpatients who received at least four doses of naldemedine revealed that the addition of magnesium or other laxatives significantly increased the average daily defecation counts when compared to naldemedine alone.
However, we also noted that the combination treatments were associated with higher rates of diarrhea. This suggests that while magnesium might enhance bowel movement frequency, it could also lead to more diarrhea, which is an important consideration for treatment.
Therefore, we concluded that introducing naldemedine either alone or with magnesium could be beneficial, but healthcare providers should carefully monitor for signs of diarrhea and adjust treatments as needed.
Analysis of 93 inpatients who received at least four doses of naldemedine revealed that the addition of magnesium or other laxatives significantly increased the average daily defecation counts when compared to naldemedine alone.
However, we also noted that the combination treatments were associated with higher rates of diarrhea. This suggests that while magnesium might enhance bowel movement frequency, it could also lead to more diarrhea, which is an important consideration for treatment.
Therefore, we concluded that introducing naldemedine either alone or with magnesium could be beneficial, but healthcare providers should carefully monitor for signs of diarrhea and adjust treatments as needed.
4
We explored how magnesium supplementation affects diarrhea, particularly in adults. In recent research, we carefully reviewed data from intervention studies conducted between 1997 and 2022, focusing mainly on single-ingredient magnesium products. Our goal was to determine whether higher doses of magnesium cause significant gastrointestinal issues, especially diarrhea, which had previously shaped the established upper intake limit.
The findings were enlightening. Out of ten studies we analyzed, including five meta-analyses and five randomized controlled trials, seven indicated no significant difference in diarrhea incidents between those receiving magnesium and those given a placebo. It was interesting to note that even at doses as high as 1200 mg per day, participants generally did not report diarrhea.
When reviewing adverse event data reported to the FDA, we found just 40 cases of gastrointestinal issues linked to magnesium supplementation. Quite tellingly, only one-third of these involved complaints about diarrhea. This suggests that the concern regarding magnesium causing significant gastrointestinal problems may be overstated.
Overall, our evaluation indicates that adults can often consume magnesium supplements above the current upper intake level without significant adverse effects related to diarrhea. This opens up opportunities for increasing magnesium intake, which could help address inadequacies in this essential nutrient for many individuals.
The findings were enlightening. Out of ten studies we analyzed, including five meta-analyses and five randomized controlled trials, seven indicated no significant difference in diarrhea incidents between those receiving magnesium and those given a placebo. It was interesting to note that even at doses as high as 1200 mg per day, participants generally did not report diarrhea.
When reviewing adverse event data reported to the FDA, we found just 40 cases of gastrointestinal issues linked to magnesium supplementation. Quite tellingly, only one-third of these involved complaints about diarrhea. This suggests that the concern regarding magnesium causing significant gastrointestinal problems may be overstated.
Overall, our evaluation indicates that adults can often consume magnesium supplements above the current upper intake level without significant adverse effects related to diarrhea. This opens up opportunities for increasing magnesium intake, which could help address inadequacies in this essential nutrient for many individuals.
References
- de Souza Goncalves L, Chu T, Master R, Chhetri PD, Gao Q, et al. Mg2+ supplementation treats secretory diarrhea in mice by activating calcium-sensing receptor in intestinal epithelial cells. J Clin Invest. 2024;134. doi:10.1172/JCI171249
- Wang Y, Xiao X, Lin Q, Song R, Wang X, et al. Hepatocyte nuclear factor 1B deletion, but not intragenic mutation, might be more susceptible to hypomagnesemia. J Diabetes Investig. 2024;15:121. doi:10.1111/jdi.14084
- Costello R, Rosanoff A, Nielsen F, West C. Perspective: Call for Re-evaluation of the Tolerable Upper Intake Level for Magnesium Supplementation in Adults. Adv Nutr. 2023;14:973. doi:10.1016/j.advnut.2023.06.008
- Kamali F, Jamee M, Sayer JA, Sadeghi-Bojd S, Golchehre Z, et al. Intestinal hypomagnesemia in an Iranian patient with a novel TRPM6 variant: a case report and review of the literature. CEN Case Rep. 2023;12:413. doi:10.1007/s13730-023-00785-8
- Cao S, Huang K, Wen X, Gao J, Cui B, et al. Dietary supplementation with potassium-magnesium sulfate modulates the antioxidant capacity, immunity, and gut microbiota in weaned piglets. Front Microbiol. 2022;13:961989. doi:10.3389/fmicb.2022.961989
- Takemura M, Niki K, Miyaguchi S, Ueda M. Naldemedine-laxative combination: retrospective inpatient study. BMJ Support Palliat Care. 2024;13:e816. doi:10.1136/spcare-2022-003685
- Sarkar KK, Mitra T, Rahman MA, Raja IM, Aktaruzzaman M, et al. Bioactivities of (Wall.) and Study against Cyclooxygenase Enzymes. Biomed Res Int. 2022;2022:1331758. doi:10.1155/2022/1331758
