NOW Supplements Melatonin
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Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Melatonin
10 mg
**

The product is found useful for the following medical conditions

Adhd details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 8 Reviews
8.7
9.5
Helps sleep issues
Most Useful Review
Excellent! A must-have. Melatonin 10mg is essential in our household. My teenage son with ADHD takes one tablet half an hour before bed, allowing his brain to calm down so he can fall asleep easily.

Anxiety details

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7
USERS' SCORE
Good
Based on 24 Reviews
8.6
9
Melatonin reduces pediatric anxiety, pain
The impact of oral melatonin on pain and anxiety reduction during venipuncture in pediatric patients: a double-blind randomized clinical trial.
Most Relevant Research
We focused on the effects of oral melatonin on anxiety and pain in children during the stressful process of venipuncture. In a double-blind, randomized controlled trial, we found that administering 0.5 mg/kg of melatonin 30 minutes before the procedure significantly reduced both pain and anxiety levels compared to a placebo.

The results showed that only 18.8% of the kids receiving melatonin reported pain, while 78.2% in the placebo group did. Furthermore, anxiety affected 44.6% of the melatonin group compared to 94.1% of those in the control group.

While melatonin appeared to improve experiences during venipuncture, its impact on the success rate was not statistically significant.
8.8
Improves sleep quality
Most Useful Review
Wonderful! HEALTHY SLEEP FROM ONE CAPSULE!! Excellent remedy for insomnia and anxiety. I bought it for my parents to ensure they get restful sleep. My father had become quite irritable due to sleepless nights. We bought the drug on a doctor's recommendation, taking one capsule at bedtime as directed. The capsule size is small, and the taste is neutral. The quality and rich ingredients, including excellent Melatonin, have worked wonders. After taking them for 2 months, everything returned to normal; they now experience calm sleep and are no longer irritable. I plan to order more soon to keep in the first aid kit.

Cancer details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 7 Reviews
8.6
9.5
Apoptosis enhancement
Most Useful Review
I take it for cancer purposes as numerous studies show high dosages (up to 160mg) significantly aid apoptosis. It's essential to increase the dosage gradually and consult your doctor before taking higher amounts. No side effects were reported at those levels, but it's better to be cautious.

Leg Cramps details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Improved sleep quality
Most Useful Review
My sleep is significantly better with this Melatonin brand. It alleviates my restless legs, leading to an improved quality of sleep.

Lung Cancer details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.6
9.5
Apoptosis assistance
Most Useful Review
I take it for cancer purposes, as numerous studies indicate that high dosages (up to 160mg) aid in apoptosis. I recommend increasing the dosage gradually and consulting your doctor about higher amounts, as no side effects were noted.

Bone Pain details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9.5
Helps with sleep
Most Useful Review
Excellent! I can't do without this melatonin as a sleep aid. I suffer from chronic bone pain and have found that it helps me get to sleep more easily. It's a great product.

Insomnia details

SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.8
USERS' SCORE
Moderately Good
Based on 51 Reviews
7.8
9
Melatonin delivery enhances sleep
Silk fibroin microneedles loaded with melatonin for circadian rhythm regulation.
Most Relevant Research
We developed a new way to deliver melatonin for those struggling with insomnia by creating microneedles made from silk fibroin. These tiny needles are designed to improve how the body absorbs melatonin, making it easier for people to get to sleep and stay asleep.

Our research shows that these microneedles can release melatonin steadily over a period of 11 hours. When we tested it on animals, we found that the microneedles maintained stable levels of drug in the bloodstream for up to 8 hours. This is promising news for individuals who may need help with their sleep cycles.

Additionally, the microneedles not only helped regulate sleep but also made a noticeable difference in anxiety levels in insomnia model rats. By improving the disrupted circadian rhythms, melatonin loaded into these microneedles could lead to significant therapeutic benefits.

We believe this innovative approach could enhance patient compliance and provide effective sleep aid for many in need. It’s an exciting development in the field of transdermal drug delivery for improving sleep quality and overcoming insomnia.
9.5
Improved sleep quality
Most Useful Review
Optimal dosage. After 30 years, there’s often a small deficit of melatonin, leading to insomnia in old age. Melatonin is vital not only for regulating sleep cycles but also for possibly inhibiting the ageing process. For the elderly, an optimal choice is 1 capsule (10 mg) before bedtime. I consistently purchase melatonin from this manufacturer and highly recommend it!

Headache details

SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.4
USERS' SCORE
Moderately Good
Based on 25 Reviews
7.5
9.5
Agomelatine relieves hypnic headaches
Case report: Hypnic headache responds to agomelatine-a potential prophylactic treatment option.
Most Relevant Research
We explored how melatonin-based treatments, particularly agomelatine, can affect headaches, focusing on hypnic headaches (HH). This form of headache typically occurs during sleep, disrupting the rest of those affected. A fascinating case of a 58-year-old woman who experienced these nocturnal headaches for three years demonstrated the potential benefits of agomelatine.

After being prescribed 25 mg of agomelatine at bedtime, she reported an impressive 80% reduction in headache frequency and severity within a month. Remarkably, her headaches completely resolved after three months, allowing her to discontinue the medication.

This case highlights the importance of exploring prophylactic treatments aimed at reducing nighttime awakenings caused by HH. Given the significant impact these headaches can have on sleep quality in older populations, treatments that target melatonin receptors could offer a promising avenue for relieving this condition.
10
Consistent benefits
Most Useful Review
I use it at bedtime; it offers great benefits, is an excellent brand, and causes no headaches.

Sleep Apnea details

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
USERS' SCORE
Moderately Good
Based on 38 Reviews
7.2
9.5
Melatonin improves sleep apnea outcomes
Effect of melatonin on insomnia and daytime sleepiness, in patients with obstructive sleep apnea and insomnia (COMISA): A randomized double-blinded placebo-controlled trial.
Most Relevant Research
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.

The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.

Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
9.5
Effective for insomnia
Most Useful Review
My sister recommended it for insomnia and sound sleep. I take it half an hour before bed, and the small capsule is top quality. I fall asleep faster and awaken refreshed full of energy. No side effects noted; I recommend ordering!

Back Pain details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 6 Reviews
7
7.5
Back acne improvement
Most Useful Review
It's easy to use for troublesome back acne and seems to be making a difference.

Autoimmune Disorder details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
USERS' SCORE
Medium or Average
Based on 3 Reviews
6.9
8
Melatonin improves MS-related symptoms
12-week melatonin intake attenuates cardiac autonomic dysfunction and oxidative stress in multiple sclerosis patients: a randomized controlled trial.
Most Relevant Research
We explored the impact of melatonin on patients with multiple sclerosis (MS), aiming to improve heart function and sleep. In a randomized controlled trial, participants received either melatonin or a placebo for 12 weeks.

We observed significant improvements in heart rate variability and markers of oxidative stress, suggesting that melatonin could enhance heart health and lower stress in MS patients. Additionally, sleep quality and quantity also improved with melatonin use.

This study indicates that melatonin might be a beneficial treatment option for managing cardiac issues and sleep disturbances in MS.
1.3
Negative experience
Most Useful Review
I tried it for a friend who wanted to give it a go. Unfortunately, it did not suit me at all, causing headaches and discomfort without helping my sleep. Consequently, I discarded the entire box.
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