We analyzed a case involving a 74-year-old man who experienced ongoing blurred vision after cataract surgery. His condition included persistent damage to the corneal epithelium, which raised concerns over the underlying reasons for his visual impairment.
To investigate, we recorded his full-field electroretinograms (ff-ERGs) to assess both scotopic and photopic responses of the retina. We also performed optical coherence tomography (OCT) to visualize changes in his retinal structure. Laboratory tests revealed a critically low level of vitamin A in his blood.
Given these findings, we diagnosed him with vitamin A deficiency (VAD) and initiated treatment with oral vitamin A supplements. Remarkably, after three months, we noted significant improvements: his visual acuity, ff-ERGs, and OCT results returned to normal. This highlighted the potential of vitamin A in managing visual issues related to cataract surgery.
Our findings suggest that vitamin A plays an important role in recovery from eye surgeries, especially for patients like him who experience corneal damage and impaired vision. We believe this case underscores the importance of monitoring vitamin A levels in patients presenting with similar complications.
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2
No significant effect on cataracts
The Antioxidants in Prevention of Cataracts Study: effects of antioxidant supplements on cataract progression in South India.
We explored the effects of antioxidant supplements, specifically beta carotene and vitamins C and E, on cataract progression in a rural South Indian population. Using a rigorous 5-year, triple-masked, placebo-controlled trial design, we carefully monitored nearly 800 participants.
Despite high compliance and thorough examinations, we observed no significant benefits from these antioxidant supplements in slowing cataract progression. The study suggests that even in populations with low dietary antioxidants, these supplements may not offer the hoped-for protection against cataracts.
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9
Vitamin A's role in cataracts
The role of dietary vitamin A in mechanisms of cataract development in the teleost lumpfish (Cyclopterus lumpus L).
We explored the relationship between dietary vitamin A and cataract development in lumpfish, a species known for its susceptibility to this eye condition. Over 18 months, lumpfish were fed diets supplemented with varying levels of vitamin A—5000, 15,000, and 120,000 IU/kg. Throughout this period, we monitored the fish for changes in weight, cataract frequency, and severity.
Our findings revealed that lower levels of vitamin A significantly reduced the occurrence of cataracts in adult lumpfish, and led to less severe cataracts, particularly notable in male fish. However, as vitamin A intake increased, we observed a positive correlation with higher oxidative stress levels in the lenses, which are associated with cataract formation.
Additionally, tissues from fish with severe cataracts exhibited high levels of cell death, known as apoptosis. This suggests that excessive vitamin A may contribute to oxidative stress and subsequently influence the development of cataracts in lumpfish. In essence, while vitamin A plays a crucial role in these fish, its higher concentrations seem to exacerbate, rather than alleviate, eye issues.
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Most Useful Reviews
9
Recommended for eyes
9 people found this helpful
Excellent product! After using beta-carotene, I found it significantly benefits eye health by preventing vision loss and reducing the risk of cataracts. It also positively influences brain function and skin health. Higher doses are safe and do not lead to hypervitaminosis. I highly recommend it for overall wellness.
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7.5
Vision improvement
8 people found this helpful
This product works wonders for sharpening vision. I have a cataract, and it has significantly slowed its progression and enhanced the vision in my good eye.
Read More
9
Significant improvement
6 people found this helpful
After one month of taking three daily, I've noticed significant improvements in my eye health. My floaters and the beginnings of cataracts are both better.
We analyzed a case involving a 74-year-old man who experienced ongoing blurred vision after cataract surgery. His condition included persistent damage to the corneal epithelium, which raised concerns over the underlying reasons for his visual impairment.
To investigate, we recorded his full-field electroretinograms (ff-ERGs) to assess both scotopic and photopic responses of the retina. We also performed optical coherence tomography (OCT) to visualize changes in his retinal structure. Laboratory tests revealed a critically low level of vitamin A in his blood.
Given these findings, we diagnosed him with vitamin A deficiency (VAD) and initiated treatment with oral vitamin A supplements. Remarkably, after three months, we noted significant improvements: his visual acuity, ff-ERGs, and OCT results returned to normal. This highlighted the potential of vitamin A in managing visual issues related to cataract surgery.
Our findings suggest that vitamin A plays an important role in recovery from eye surgeries, especially for patients like him who experience corneal damage and impaired vision. We believe this case underscores the importance of monitoring vitamin A levels in patients presenting with similar complications.
Read More
9
Vitamin A's role in cataracts
The role of dietary vitamin A in mechanisms of cataract development in the teleost lumpfish (Cyclopterus lumpus L).
We explored the relationship between dietary vitamin A and cataract development in lumpfish, a species known for its susceptibility to this eye condition. Over 18 months, lumpfish were fed diets supplemented with varying levels of vitamin A—5000, 15,000, and 120,000 IU/kg. Throughout this period, we monitored the fish for changes in weight, cataract frequency, and severity.
Our findings revealed that lower levels of vitamin A significantly reduced the occurrence of cataracts in adult lumpfish, and led to less severe cataracts, particularly notable in male fish. However, as vitamin A intake increased, we observed a positive correlation with higher oxidative stress levels in the lenses, which are associated with cataract formation.
Additionally, tissues from fish with severe cataracts exhibited high levels of cell death, known as apoptosis. This suggests that excessive vitamin A may contribute to oxidative stress and subsequently influence the development of cataracts in lumpfish. In essence, while vitamin A plays a crucial role in these fish, its higher concentrations seem to exacerbate, rather than alleviate, eye issues.
Read More
9
Vitamin A's dietary impact
Food components and ocular pathophysiology: a critical appraisal of the role of oxidative mechanisms.
We examined the connection between vitamin A and cataracts, particularly its role in dietary sources versus supplements. Our findings indicated that vitamin A, when consumed through food, seems to offer a protective effect against cataracts. This is an encouraging note for those looking into nutritional strategies to support eye health.
On the other hand, when vitamin A is taken in supplement form, we observed a contrasting outcome—it did not provide the same benefits. In fact, it might not be as effective in preventing cataracts as previously thought. This shows us that getting nutrients from a balanced diet is crucial, while high doses of supplements could be less helpful, or even risky, for eye conditions.
Overall, our exploration suggests a focus on whole foods rich in vitamin A as a smarter move for those concerned about cataracts, rather than leaning on supplements.
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9
Investigating Luffa cylindrica in cataracts
Effect of standardized fruit extract of Luffa cylindrica on oxidative stress markers in hydrogen peroxide induced cataract.
We investigated how Luffa cylindrica (LCE) fruit extract might influence cataract formation, particularly focusing on the oxidative stress markers associated with this condition. In a laboratory setting, isolated goat lenses were exposed to hydrogen peroxide—a known cataract inducer—for 72 hours at body temperature.
We tested several concentrations of LCE, from 5 to 30 µg/ml, alongside a control group. Throughout the incubation, we examined the lenses for any changes in appearance and transparency. Notably, we measured biochemical markers, including superoxide dismutase (SOD), reduced glutathione (GSH), total protein content (TPC), and malondialdehyde (MDA)—essential indicators of oxidative stress.
Our findings revealed that SOD, GSH, and TPC levels increased with higher concentrations of LCE, suggesting the extract's potential protective effects. Conversely, MDA levels decreased, indicating reduced oxidative stress. The lenses treated with 25 µg/ml of LCE maintained clarity for a significant duration, showing that this level of extract could potentially delay or prevent cataract progression.
While our study highlights the benefits of LCE related to its antioxidant properties, the exact contributions of Vitamin A in this natural extract, while noted, were not isolated for specific effects. Overall, our research underscores the importance of exploring natural remedies like Luffa cylindrica in fighting cataract development, paving the way for future studies to fully harness its potential.
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8
Antioxidants linked to cataract risk
Blood levels of vitamin C, carotenoids and retinol are inversely associated with cataract in a North Indian population.
We explored the connection between blood antioxidants, like beta carotene and vitamin C, and cataracts in individuals aged 50 and older from various villages in North India. Our cross-sectional study involved interviews and lens photography to get a clear picture of eye health.
While we found that lower levels of antioxidants were associated with higher odds of cataract formation, the evidence primarily highlighted vitamin C, zeaxanthin, and retinol.
Notably, beta carotene specifically did not show a significant benefit. Overall, the results indicate that increasing blood antioxidant levels may help reduce cataract risk.
Excellent product! After using beta-carotene, I found it significantly benefits eye health by preventing vision loss and reducing the risk of cataracts. It also positively influences brain function and skin health. Higher doses are safe and do not lead to hypervitaminosis. I highly recommend it for overall wellness.
Read More
7.5
Vision improvement
8 people found this helpful
This product works wonders for sharpening vision. I have a cataract, and it has significantly slowed its progression and enhanced the vision in my good eye.
Read More
9
Significant improvement
6 people found this helpful
After one month of taking three daily, I've noticed significant improvements in my eye health. My floaters and the beginnings of cataracts are both better.
Read More
9
Vision loss prevention
4 people found this helpful
Excellent product! It promotes eye health, prevents vision loss, and reduces the risk of cataracts. Beta-carotene enhances brain function, concentration, and memory. It also aids in healing wounds and protects the skin from sun damage. As a precursor to vitamin A, it should be consumed with fats for better absorption. I've developed a regimen to take it on the first 10 days of each month. The product’s quality from a well-known brand is very reassuring.
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9
Antioxidant benefits
4 people found this helpful
Beta-carotene acts as an antioxidant, safeguarding skin cells from damage and promoting eye health by preventing vision loss and diminishing cataract risk. It positively influences brain function, concentration, and memory, while also supporting skin recovery against sun damage.
A cataract is a clouding of the eye's natural lens, which is located behind the iris and pupil. This lens is responsible for focusing light onto the retina, allowing us to see clearly. With a cataract, the lens becomes opaque, leading to blurred or distorted vision, difficulty with glare, and sometimes even colors appearing faded. Cataracts typically develop slowly and can affect one or both eyes. They are most commonly associated with aging, but other factors, such as genetics, certain medical conditions, medications, and even prolonged exposure to ultraviolet light, can also contribute to their formation.
While cataracts are generally a part of the aging process, they can be treated effectively through surgical intervention. The surgery involves removing the cloudy lens and often replacing it with an artificial intraocular lens, allowing for improved vision. Most patients experience significant improvement in their sight following surgery, and it is considered one of the most common and safest procedures performed worldwide. If you're experiencing symptoms of cataracts or are concerned about your vision, it's essential to consult an eye care professional for proper evaluation and personalized treatment options.
Beta carotene is a natural pigment found in many fruits and vegetables, particularly those that are orange, yellow, and green. It is a type of carotenoid, which is a class of antioxidants that give plants their vibrant colors. The body converts beta carotene into vitamin A (retinol), which is essential for maintaining healthy vision, skin, and immune function. Foods rich in beta carotene include carrots, sweet potatoes, butternut squash, and leafy greens like spinach and kale.
In addition to its role in promoting overall health, beta carotene is attractive to those seeking to enhance their diets with antioxidant-rich foods. While supplementation can be beneficial for those with specific deficiencies, obtaining nutrients through whole foods is generally recommended. Most people can safely consume beta carotene through their diet, but it's worth noting that excessive intake from supplements can lead to skin discoloration and other health issues. Therefore, incorporating a variety of colorful fruits and vegetables into your daily meals is the best way to enjoy the benefits of beta carotene while ensuring a balanced intake of essential nutrients.
Beta-carotene is a type of antioxidant that is often associated with supporting eye health, particularly due to its conversion into vitamin A in the body. While some studies suggest that a diet rich in antioxidants, including beta-carotene, may be beneficial for maintaining overall eye health and potentially lowering the risk of various eye diseases, including cataracts, the evidence specifically linking beta-carotene to the prevention or treatment of cataracts remains inconclusive.
Researchers continue to investigate the complex relationship between diet, antioxidants, and eye health, but it’s important to note that cataracts are mainly influenced by age, genetics, and environmental factors like UV exposure. Therefore, while including beta-carotene-rich foods, such as carrots, sweet potatoes, and leafy greens, can be part of a balanced diet for eye health, it should not be relied upon solely for cataract prevention. As always, consulting a healthcare provider for personalized recommendations and a comprehensive approach to eye care is highly advised.
Based on user reviews, the timeline for seeing results from beta-carotene supplementation can vary. Many users reported noticeable improvements in their eye health within a month of consistent use. For instance, one user mentioned that after taking the supplement for one month, they experienced significant improvement in their eye health and a reduction in the beginnings of cataracts Read Review. Another individual noted that after just two weeks of use, they saw diminished eye fatigue and clearer vision, especially in low light conditions Read Review.
It's important to remember that individual experiences may differ, and while some may see results sooner, others may require more prolonged usage to experience benefits. If you're considering beta-carotene for cataract support, it may be worthwhile to monitor your progress over a month or two while maintaining a consistent dosage.
The relationship between nutritional supplements and cataract prevention is a subject of ongoing research. Numerous studies point to the potential benefits of certain antioxidants, particularly beta carotene and vitamin A, in reducing cataract risk. For instance, a review of 25 studies found that higher intake of beta carotene is linked to lower cataract development probability, although not all antioxidants evaluated showed significant results [1]. Another study highlighted a significant reduction in cataract risk associated with increased dietary vitamin A, emphasizing its protective role when consumed through food rather than supplements [1]. However, randomized controlled trials often yield inconclusive results regarding these vitamins' effectiveness, indicating that more research is needed to establish a definitive link [2].
Particularly noteworthy is the evidence suggesting that while certain antioxidants show promise, like lutein and zeaxanthin, beta carotene alone may not provide significant protection against cataracts [6]. Studies also reveal that excessive levels of beta carotene can potentially increase cataract risk, complicating the narrative [5]. Overall, dietary approaches rich in antioxidants may enhance eye health, but reliance on supplements should be approached with caution. Therefore, if you're considering these supplements for cataract prevention, consulting with a healthcare professional is advisable.
Based on user reviews, many individuals have reported significant improvements in their eye health after starting beta-carotene supplementation. For example, one user noted a marked enhancement in vision clarity and a reduction in eye fatigue within just two weeks of use, particularly in low-light situations Read Review. Another reviewer mentioned that after a month of consistent intake, both their floaters and early cataract symptoms improved considerably Read Review. Several users highlighted the compound’s protective abilities against vision loss and its role in lowering the risk of cataracts, with claims that beta-carotene fosters not only eye health but also benefits brain function and memory Read Review.
Additionally, people have shared positive experiences regarding the overall improvement in well-being when incorporating beta-carotene into their regimen. Some users have noted enhancements in skin tone and protection from sun damage Read Review. It’s essential to understand that while many have reported these benefits, individual results can vary, and not everyone may experience the same outcomes.
Based on user reviews, many individuals have reported combining beta-carotene with other supplements, particularly vitamin D3, to enhance overall well-being and specifically eye health. One user noted that taking vitamin D3 in the morning and beta-carotene in the evening resulted in improvements in their complexion and significantly enhanced their visual clarity, even reducing the effects of senile cataracts Read Review. This synergistic approach seems to not only affect their complexion positively but also aid in their vision stability, suggesting that a combination of these two supplements might offer compounded benefits for eye health.
Users have generally expressed that beta-carotene can be safely used in conjunction with other dietary supplements without adverse effects. For instance, one user mentioned that higher doses of beta-carotene are safe and do not lead to hypervitaminosis, suggesting a level of tolerance when taken alongside other nutritional aids Read Review. However, while there are anecdotal reports of various combinations, individual experiences can vary widely, and it’s important to approach supplementation with personal health needs in mind.
Users report varying doses of beta-carotene for treating cataracts, with a common thread indicating that higher doses may be safe and effective. One reviewer noted taking three doses daily, experiencing significant improvements in eye health and decreased symptoms related to cataracts within a month Read Review. Additionally, another user highlighted a preference for quality natural sources, mentioning enhanced clarity and color perception after two weeks of using a specific product, emphasizing that they can read better even with existing cataracts Read Review.
Overall, beta-carotene users consistently emphasize its benefits for preventing vision loss and lowering cataract risk, along with additional advantages for skin health and cognitive function Read Review. While specific dosage recommendations vary, users seem assured that higher doses are generally safe and beneficial, as excess amounts do not lead to adverse effects due to the body's regulation of conversion to retinol Read Review. However, no specific universal dosage was defined across reviews, suggesting users may need to find their optimal amount through personal experimentation and medical guidance.
9
Significant improvement
6 people found this helpful
After one month of taking three daily, I've noticed significant improvements in my eye health. My floaters and the beginnings of cataracts are both better.
9
Improved vision clarity
1 people found this helpful
I often experience eye strain due to prolonged computer use, and an ophthalmologist recommended quality 100% natural oceanic beta-carotene. After two weeks, my eye fatigue diminished, and I noticed improvements in my vision clarity, especially in low light conditions, alongside restored brightness and colour perception. This powerful antioxidant seems to nourish the eyes and may help prevent age-related changes that could lead to cataracts. I appreciate the product’s quality from a reliable manufacturer. I hope this review aids your decision!
9
Brain function improvement
1 people found this helpful
Beta-carotene is great for eye health; it prevents vision loss and reduces cataract development risk. It enhances brain function, improving concentration and memory. Unlike vitamin A, it’s safe in higher doses, as only necessary amounts are converted into retinol, while excess accumulates safely.
9
Improved eyesight
I noted in my reviews that if you take vitamin D3 in the morning and beta-carotene in the evening, it positively affects your complexion. My son used to tan evenly until he turned twelve, after which he became pale and could only burn his nose. Recently, we learned about beta-carotene, and since taking it in autumn and winter, his complexion has improved from pale to a more even tone, which I’m very pleased about. I have poor eyesight and had difficulty reading, even with glasses and a magnifying glass. However, after taking beta-carotene, I can read with my glasses and occasionally without them. Though I have senile cataracts, my eyesight has improved significantly, and the foggy effect is gone. I definitely recommend it as it has helped me greatly.
9
Recommended for eyes
9 people found this helpful
Excellent product! After using beta-carotene, I found it significantly benefits eye health by preventing vision loss and reducing the risk of cataracts. It also positively influences brain function and skin health. Higher doses are safe and do not lead to hypervitaminosis. I highly recommend it for overall wellness.
9
Protects eye health
3 people found this helpful
Beneficial for eye health, beta-carotene prevents vision impairment and cataract development. It positively influences brain function and helps heal wounds while protecting the skin from harsh conditions.
7
Beta carotene linked to cataract protection
The potential role of nutrition on lens pathology: a systematic review and meta-analysis.
We explored the impact of nutritional antioxidants on the prevention of cataracts, focusing on various micronutrients such as vitamins A, C, E, and carotenoids. After examining 25 studies involving nearly 300,000 participants, we found that beta carotene showed some protective effects against cataract development, with statistical significance. However, it's important to note that not all antioxidants evaluated, including vitamin E and A, demonstrated significant benefits. More research, particularly interventional studies, is necessary to better understand these relationships.
4
Beta carotene and cataract risk
Dietary vitamin and carotenoid intake and risk of age-related cataract.
We explored the relationship between dietary vitamins and carotenoids, like beta carotene, and the risk of age-related cataract (ARC) through a review of various studies. While cohort studies indicated that higher intake of these nutrients can significantly reduce ARC risk, the results from randomized controlled trials were not as conclusive for beta carotene specifically.
In these trials, beta carotene did not demonstrate a significant effect compared to placebo. However, the evidence from cohort studies suggests that increasing beta carotene intake may still benefit overall eye health.
2
Beta-carotene shows no cataract benefit
Association of blood antioxidants and vitamins with risk of age-related cataract: a meta-analysis of observational studies.
We aimed to see if there's a link between blood antioxidants and vitamin levels and age-related cataract risk through a thorough review of 13 studies involving nearly 19,000 participants. Our findings indicated that some antioxidants like vitamin E, α-carotene, lutein, and zeaxanthin were indeed linked with a lower risk of cataracts.
Notably, beta-carotene did not show significant benefits in preventing cataracts, with an odds ratio indicating no strong association. This suggests a need for more targeted studies to further explore the potential of these nutrients in cataract prevention.
4
No significant benefit found
Nutrition effects on ocular diseases in the aging eye.
We reviewed various clinical trials that examined the role of nutritional supplements, including beta carotene, in treating age-related cataracts and macular degeneration. Our findings indicate that beta carotene didn't show a significant benefit for cataracts and, in fact, was linked to a higher risk of certain cataract types.
While some trials showed multivitamins might reduce cataract progression, the benefits of beta carotene were overshadowed by concerns about lung cancer risk for former smokers. Therefore, alternatives like lutein and zeaxanthin are suggested for future studies.
References
Sideri O, Tsaousis KT, Li HJ, Viskadouraki M, Tsinopoulos IT. The potential role of nutrition on lens pathology: a systematic review and meta-analysis. Surv Ophthalmol. 2019;64:668. 10.1016/j.survophthal.2019.03.003
Jiang H, Yin Y, Wu CR, Liu Y, Guo F, et al. Dietary vitamin and carotenoid intake and risk of age-related cataract. Am J Clin Nutr. 2019;109:43. 10.1093/ajcn/nqy270
Mamatha BS, Nidhi B, Padmaprabhu CA, Pallavi P, Vallikannan B. Risk Factors for Nuclear and Cortical Cataracts: A Hospital Based Study. J Ophthalmic Vis Res. 2015;10:243. 10.4103/2008-322X.170356
Wang A, Han J, Jiang Y, Zhang D. Association of vitamin A and β-carotene with risk for age-related cataract: a meta-analysis. Nutrition. 2014;30:1113. 10.1016/j.nut.2014.02.025
Chew EY. Nutrition effects on ocular diseases in the aging eye. Invest Ophthalmol Vis Sci. 2013;54:ORSF42. 10.1167/iovs13-12914
Cui YH, Jing CX, Pan HW. Association of blood antioxidants and vitamins with risk of age-related cataract: a meta-analysis of observational studies. Am J Clin Nutr. 2013;98:778. 10.3945/ajcn.112.053835
Agte V, Tarwadi K. The importance of nutrition in the prevention of ocular disease with special reference to cataract. Ophthalmic Res. 2010;44:166. 10.1159/000316477
Tan AG, Mitchell P, Flood VM, Burlutsky G, Rochtchina E, et al. Antioxidant nutrient intake and the long-term incidence of age-related cataract: the Blue Mountains Eye Study. Am J Clin Nutr. 2008;87:1899.
Dherani M, Murthy GV, Gupta SK, Young IS, Maraini G, et al. Blood levels of vitamin C, carotenoids and retinol are inversely associated with cataract in a North Indian population. Invest Ophthalmol Vis Sci. 2008;49:3328. 10.1167/iovs.07-1202
Delcourt C, Carrière I, Delage M, Barberger-Gateau P, Schalch W. Plasma lutein and zeaxanthin and other carotenoids as modifiable risk factors for age-related maculopathy and cataract: the POLA Study. Invest Ophthalmol Vis Sci. 2006;47:2329.
Gritz DC, Srinivasan M, Smith SD, Kim U, Lietman TM, et al. The Antioxidants in Prevention of Cataracts Study: effects of antioxidant supplements on cataract progression in South India. Br J Ophthalmol. 2006;90:847.
Kutlu M, Naziroğlu M, Simşek H, Yilmaz T, Sahap Kükner A. Moderate exercise combined with dietary vitamins C and E counteracts oxidative stress in the kidney and lens of streptozotocin-induced diabetic-rat. Int J Vitam Nutr Res. 2005;75:71.
Yamada F, Kato K, Nagashima R, Yonekawa Y, Kashima Y, et al. Case of persistent corneal epithelial damage after cataract surgery leading to diagnosis of vitamin A deficiency. Doc Ophthalmol. 2024;148:121. 10.1007/s10633-023-09963-6
Deering MJ, Paradis H, Ahmad R, Al-Mehiawi AS, Gendron RL. The role of dietary vitamin A in mechanisms of cataract development in the teleost lumpfish (Cyclopterus lumpus L). J Fish Dis. 2024;47:e13899. 10.1111/jfd.13899
Raman R, Vaghefi E, Braakhuis AJ. Food components and ocular pathophysiology: a critical appraisal of the role of oxidative mechanisms. Asia Pac J Clin Nutr. 2017;26:572. 10.6133/apjcn.082016.01
Dubey S, Saha S, Kaithwas G, Saraf SA. Effect of standardized fruit extract of Luffa cylindrica on oxidative stress markers in hydrogen peroxide induced cataract. Indian J Pharmacol. 2015;47:644. 10.4103/0253-7613.169586