' 
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.9
USERS' SCORE
Good
Based on 1 Review
8.4
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin A (100% as Beta-Carotene)(from Blakeslea trispora and Sunflower Oil)
7,500 mcg
833%
Top Medical Research Studies
9.5
Vitamin A improves post-surgery vision
Case of persistent corneal epithelial damage after cataract surgery leading to diagnosis of vitamin A deficiency.
Directly impacts visual outcomes
We analyzed a case involving a 74-year-old man who experienced ongoing blurred vision after cataract surgery. His condition included persistent damage to the corneal epithelium, which raised concerns over the underlying reasons for his visual impairment.
To investigate, we recorded his full-field electroretinograms (ff-ERGs) to assess both scotopic and photopic responses of the retina. We also performed optical coherence tomography (OCT) to visualize changes in his retinal structure. Laboratory tests revealed a critically low level of vitamin A in his blood.
Given these findings, we diagnosed him with vitamin A deficiency (VAD) and initiated treatment with oral vitamin A supplements. Remarkably, after three months, we noted significant improvements: his visual acuity, ff-ERGs, and OCT results returned to normal. This highlighted the potential of vitamin A in managing visual issues related to cataract surgery.
Our findings suggest that vitamin A plays an important role in recovery from eye surgeries, especially for patients like him who experience corneal damage and impaired vision. We believe this case underscores the importance of monitoring vitamin A levels in patients presenting with similar complications.
To investigate, we recorded his full-field electroretinograms (ff-ERGs) to assess both scotopic and photopic responses of the retina. We also performed optical coherence tomography (OCT) to visualize changes in his retinal structure. Laboratory tests revealed a critically low level of vitamin A in his blood.
Given these findings, we diagnosed him with vitamin A deficiency (VAD) and initiated treatment with oral vitamin A supplements. Remarkably, after three months, we noted significant improvements: his visual acuity, ff-ERGs, and OCT results returned to normal. This highlighted the potential of vitamin A in managing visual issues related to cataract surgery.
Our findings suggest that vitamin A plays an important role in recovery from eye surgeries, especially for patients like him who experience corneal damage and impaired vision. We believe this case underscores the importance of monitoring vitamin A levels in patients presenting with similar complications.
Read More
9
Vitamin A's role in cataracts
The role of dietary vitamin A in mechanisms of cataract development in the teleost lumpfish (Cyclopterus lumpus L).
Study directly examines vitamin A effects
We explored the relationship between dietary vitamin A and cataract development in lumpfish, a species known for its susceptibility to this eye condition. Over 18 months, lumpfish were fed diets supplemented with varying levels of vitamin A—5000, 15,000, and 120,000 IU/kg. Throughout this period, we monitored the fish for changes in weight, cataract frequency, and severity.
Our findings revealed that lower levels of vitamin A significantly reduced the occurrence of cataracts in adult lumpfish, and led to less severe cataracts, particularly notable in male fish. However, as vitamin A intake increased, we observed a positive correlation with higher oxidative stress levels in the lenses, which are associated with cataract formation.
Additionally, tissues from fish with severe cataracts exhibited high levels of cell death, known as apoptosis. This suggests that excessive vitamin A may contribute to oxidative stress and subsequently influence the development of cataracts in lumpfish. In essence, while vitamin A plays a crucial role in these fish, its higher concentrations seem to exacerbate, rather than alleviate, eye issues.
Our findings revealed that lower levels of vitamin A significantly reduced the occurrence of cataracts in adult lumpfish, and led to less severe cataracts, particularly notable in male fish. However, as vitamin A intake increased, we observed a positive correlation with higher oxidative stress levels in the lenses, which are associated with cataract formation.
Additionally, tissues from fish with severe cataracts exhibited high levels of cell death, known as apoptosis. This suggests that excessive vitamin A may contribute to oxidative stress and subsequently influence the development of cataracts in lumpfish. In essence, while vitamin A plays a crucial role in these fish, its higher concentrations seem to exacerbate, rather than alleviate, eye issues.
Read More
9
Investigating Luffa cylindrica in cataracts
Effect of standardized fruit extract of Luffa cylindrica on oxidative stress markers in hydrogen peroxide induced cataract.
Moderately relevant due to vitamin context
We investigated how Luffa cylindrica (LCE) fruit extract might influence cataract formation, particularly focusing on the oxidative stress markers associated with this condition. In a laboratory setting, isolated goat lenses were exposed to hydrogen peroxide—a known cataract inducer—for 72 hours at body temperature.
We tested several concentrations of LCE, from 5 to 30 µg/ml, alongside a control group. Throughout the incubation, we examined the lenses for any changes in appearance and transparency. Notably, we measured biochemical markers, including superoxide dismutase (SOD), reduced glutathione (GSH), total protein content (TPC), and malondialdehyde (MDA)—essential indicators of oxidative stress.
Our findings revealed that SOD, GSH, and TPC levels increased with higher concentrations of LCE, suggesting the extract's potential protective effects. Conversely, MDA levels decreased, indicating reduced oxidative stress. The lenses treated with 25 µg/ml of LCE maintained clarity for a significant duration, showing that this level of extract could potentially delay or prevent cataract progression.
While our study highlights the benefits of LCE related to its antioxidant properties, the exact contributions of Vitamin A in this natural extract, while noted, were not isolated for specific effects. Overall, our research underscores the importance of exploring natural remedies like Luffa cylindrica in fighting cataract development, paving the way for future studies to fully harness its potential.
We tested several concentrations of LCE, from 5 to 30 µg/ml, alongside a control group. Throughout the incubation, we examined the lenses for any changes in appearance and transparency. Notably, we measured biochemical markers, including superoxide dismutase (SOD), reduced glutathione (GSH), total protein content (TPC), and malondialdehyde (MDA)—essential indicators of oxidative stress.
Our findings revealed that SOD, GSH, and TPC levels increased with higher concentrations of LCE, suggesting the extract's potential protective effects. Conversely, MDA levels decreased, indicating reduced oxidative stress. The lenses treated with 25 µg/ml of LCE maintained clarity for a significant duration, showing that this level of extract could potentially delay or prevent cataract progression.
While our study highlights the benefits of LCE related to its antioxidant properties, the exact contributions of Vitamin A in this natural extract, while noted, were not isolated for specific effects. Overall, our research underscores the importance of exploring natural remedies like Luffa cylindrica in fighting cataract development, paving the way for future studies to fully harness its potential.
Read More
Most Useful Reviews
7.5
Vision improvement
This product works wonders for sharpening vision. I have a cataract, and it has significantly slowed its progression and enhanced the vision in my good eye.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.9
- All Researches
9.5
Vitamin A improves post-surgery vision
Case of persistent corneal epithelial damage after cataract surgery leading to diagnosis of vitamin A deficiency.
Directly impacts visual outcomes
We analyzed a case involving a 74-year-old man who experienced ongoing blurred vision after cataract surgery. His condition included persistent damage to the corneal epithelium, which raised concerns over the underlying reasons for his visual impairment.
To investigate, we recorded his full-field electroretinograms (ff-ERGs) to assess both scotopic and photopic responses of the retina. We also performed optical coherence tomography (OCT) to visualize changes in his retinal structure. Laboratory tests revealed a critically low level of vitamin A in his blood.
Given these findings, we diagnosed him with vitamin A deficiency (VAD) and initiated treatment with oral vitamin A supplements. Remarkably, after three months, we noted significant improvements: his visual acuity, ff-ERGs, and OCT results returned to normal. This highlighted the potential of vitamin A in managing visual issues related to cataract surgery.
Our findings suggest that vitamin A plays an important role in recovery from eye surgeries, especially for patients like him who experience corneal damage and impaired vision. We believe this case underscores the importance of monitoring vitamin A levels in patients presenting with similar complications.
To investigate, we recorded his full-field electroretinograms (ff-ERGs) to assess both scotopic and photopic responses of the retina. We also performed optical coherence tomography (OCT) to visualize changes in his retinal structure. Laboratory tests revealed a critically low level of vitamin A in his blood.
Given these findings, we diagnosed him with vitamin A deficiency (VAD) and initiated treatment with oral vitamin A supplements. Remarkably, after three months, we noted significant improvements: his visual acuity, ff-ERGs, and OCT results returned to normal. This highlighted the potential of vitamin A in managing visual issues related to cataract surgery.
Our findings suggest that vitamin A plays an important role in recovery from eye surgeries, especially for patients like him who experience corneal damage and impaired vision. We believe this case underscores the importance of monitoring vitamin A levels in patients presenting with similar complications.
Read More
9
Vitamin A's role in cataracts
The role of dietary vitamin A in mechanisms of cataract development in the teleost lumpfish (Cyclopterus lumpus L).
Study directly examines vitamin A effects
We explored the relationship between dietary vitamin A and cataract development in lumpfish, a species known for its susceptibility to this eye condition. Over 18 months, lumpfish were fed diets supplemented with varying levels of vitamin A—5000, 15,000, and 120,000 IU/kg. Throughout this period, we monitored the fish for changes in weight, cataract frequency, and severity.
Our findings revealed that lower levels of vitamin A significantly reduced the occurrence of cataracts in adult lumpfish, and led to less severe cataracts, particularly notable in male fish. However, as vitamin A intake increased, we observed a positive correlation with higher oxidative stress levels in the lenses, which are associated with cataract formation.
Additionally, tissues from fish with severe cataracts exhibited high levels of cell death, known as apoptosis. This suggests that excessive vitamin A may contribute to oxidative stress and subsequently influence the development of cataracts in lumpfish. In essence, while vitamin A plays a crucial role in these fish, its higher concentrations seem to exacerbate, rather than alleviate, eye issues.
Our findings revealed that lower levels of vitamin A significantly reduced the occurrence of cataracts in adult lumpfish, and led to less severe cataracts, particularly notable in male fish. However, as vitamin A intake increased, we observed a positive correlation with higher oxidative stress levels in the lenses, which are associated with cataract formation.
Additionally, tissues from fish with severe cataracts exhibited high levels of cell death, known as apoptosis. This suggests that excessive vitamin A may contribute to oxidative stress and subsequently influence the development of cataracts in lumpfish. In essence, while vitamin A plays a crucial role in these fish, its higher concentrations seem to exacerbate, rather than alleviate, eye issues.
Read More
9
Vitamin A's dietary impact
Food components and ocular pathophysiology: a critical appraisal of the role of oxidative mechanisms.
Relevant impact on cataract prevention
We examined the connection between vitamin A and cataracts, particularly its role in dietary sources versus supplements. Our findings indicated that vitamin A, when consumed through food, seems to offer a protective effect against cataracts. This is an encouraging note for those looking into nutritional strategies to support eye health.
On the other hand, when vitamin A is taken in supplement form, we observed a contrasting outcome—it did not provide the same benefits. In fact, it might not be as effective in preventing cataracts as previously thought. This shows us that getting nutrients from a balanced diet is crucial, while high doses of supplements could be less helpful, or even risky, for eye conditions.
Overall, our exploration suggests a focus on whole foods rich in vitamin A as a smarter move for those concerned about cataracts, rather than leaning on supplements.
On the other hand, when vitamin A is taken in supplement form, we observed a contrasting outcome—it did not provide the same benefits. In fact, it might not be as effective in preventing cataracts as previously thought. This shows us that getting nutrients from a balanced diet is crucial, while high doses of supplements could be less helpful, or even risky, for eye conditions.
Overall, our exploration suggests a focus on whole foods rich in vitamin A as a smarter move for those concerned about cataracts, rather than leaning on supplements.
Read More
9
Investigating Luffa cylindrica in cataracts
Effect of standardized fruit extract of Luffa cylindrica on oxidative stress markers in hydrogen peroxide induced cataract.
Moderately relevant due to vitamin context
We investigated how Luffa cylindrica (LCE) fruit extract might influence cataract formation, particularly focusing on the oxidative stress markers associated with this condition. In a laboratory setting, isolated goat lenses were exposed to hydrogen peroxide—a known cataract inducer—for 72 hours at body temperature.
We tested several concentrations of LCE, from 5 to 30 µg/ml, alongside a control group. Throughout the incubation, we examined the lenses for any changes in appearance and transparency. Notably, we measured biochemical markers, including superoxide dismutase (SOD), reduced glutathione (GSH), total protein content (TPC), and malondialdehyde (MDA)—essential indicators of oxidative stress.
Our findings revealed that SOD, GSH, and TPC levels increased with higher concentrations of LCE, suggesting the extract's potential protective effects. Conversely, MDA levels decreased, indicating reduced oxidative stress. The lenses treated with 25 µg/ml of LCE maintained clarity for a significant duration, showing that this level of extract could potentially delay or prevent cataract progression.
While our study highlights the benefits of LCE related to its antioxidant properties, the exact contributions of Vitamin A in this natural extract, while noted, were not isolated for specific effects. Overall, our research underscores the importance of exploring natural remedies like Luffa cylindrica in fighting cataract development, paving the way for future studies to fully harness its potential.
We tested several concentrations of LCE, from 5 to 30 µg/ml, alongside a control group. Throughout the incubation, we examined the lenses for any changes in appearance and transparency. Notably, we measured biochemical markers, including superoxide dismutase (SOD), reduced glutathione (GSH), total protein content (TPC), and malondialdehyde (MDA)—essential indicators of oxidative stress.
Our findings revealed that SOD, GSH, and TPC levels increased with higher concentrations of LCE, suggesting the extract's potential protective effects. Conversely, MDA levels decreased, indicating reduced oxidative stress. The lenses treated with 25 µg/ml of LCE maintained clarity for a significant duration, showing that this level of extract could potentially delay or prevent cataract progression.
While our study highlights the benefits of LCE related to its antioxidant properties, the exact contributions of Vitamin A in this natural extract, while noted, were not isolated for specific effects. Overall, our research underscores the importance of exploring natural remedies like Luffa cylindrica in fighting cataract development, paving the way for future studies to fully harness its potential.
Read More
8
Vitamin A linked to cataract reduction
Dietary vitamin and carotenoid intake and risk of age-related cataract.
Moderate relevance due to context
We delved into how dietary vitamin A might influence the risk of developing age-related cataracts. By examining data from eight randomized controlled trials and twelve cohort studies, we found that higher intake of vitamin A is associated with a lower risk of cataracts according to cohort studies.
The results showed a significant reduction in risk, with an estimated risk ratio of 0.81, indicating that for every increase in vitamin A intake, the likelihood of developing cataracts decreased. This is encouraging, as it suggests that boosting our vitamin A intake could play a role in promoting eye health.
However, when we looked at randomized controlled trials specifically, the evidence was less conclusive. These studies did not demonstrate a significant reduction in cataract risk when participants received vitamin A or related supplements compared to a placebo.
While it appears that vitamin A may indeed be beneficial for reducing cataract risk based on cohort studies, the randomized controlled trials suggest we need more research to clarify its effectiveness. Understanding how nutrition, specifically vitamin A, impacts eye health is essential as we continue to explore potential preventative strategies for age-related cataracts.
The results showed a significant reduction in risk, with an estimated risk ratio of 0.81, indicating that for every increase in vitamin A intake, the likelihood of developing cataracts decreased. This is encouraging, as it suggests that boosting our vitamin A intake could play a role in promoting eye health.
However, when we looked at randomized controlled trials specifically, the evidence was less conclusive. These studies did not demonstrate a significant reduction in cataract risk when participants received vitamin A or related supplements compared to a placebo.
While it appears that vitamin A may indeed be beneficial for reducing cataract risk based on cohort studies, the randomized controlled trials suggest we need more research to clarify its effectiveness. Understanding how nutrition, specifically vitamin A, impacts eye health is essential as we continue to explore potential preventative strategies for age-related cataracts.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Vision improvement
This product works wonders for sharpening vision. I have a cataract, and it has significantly slowed its progression and enhanced the vision in my good eye.
