Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8
USERS' SCORE
Questionable
Based on 16 Reviews
5.1
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Oregano Oil (Origanum vulgare) min. 55% Carvacrol)
0.2 ml / 181 mg
**
Ginger Oil (Zingiber officinale)
0.02 ml / 17.6 mg
**
Fennel Oil (Foeniculum vulgare)
0.02 ml / 19.3 mg
**

Top Medical Research Studies

9.5
Oregano shows promise against diarrhea
We explored the potential of oregano, specifically Origanum majorana, to combat Blastocystis spp. cysts that are associated with gastrointestinal issues like diarrhea. In our investigation, we applied aqueous extracts of oregano and another herb, Foeniculum vulgare, to assess their efficacy in vitro.

By measuring the viability of human Peripheral Blood Mononuclear Cells and observing the response of isolated Blastocystis cysts to various concentrations of the herbal extracts, we aimed to uncover their anti-parasitic properties. Our results revealed that oregano extract at higher doses exhibited impressive effectiveness, achieving up to 100% efficacy after 72 hours, which was comparable to a standard drug used for treatment.

In contrast, while Foeniculum vulgare also showed some benefit, its efficacy was noticeably lower, reaching just 70.7% after the same duration. Both herbs featured high levels of beneficial compounds, including phenolic and flavonoid components, known for their antioxidant properties. This discovery paints a hopeful picture for using oregano as a natural remedy for managing diarrhea caused by these specific parasites.
Read More
9
Oregano oil effective against CDI
We explored the potential of essential oils from spice herbs, particularly oregano, in managing Clostridioides difficile infections (CDI), which are known to cause severe diarrhea in hospitalized patients. This study focused on three types of essential oils—wild oregano, garlic, and black pepper—and their antibacterial properties against various C. difficile strains. Our goal was to assess how effectively these oils could combat bacterial growth and inhibit biofilm formation under laboratory conditions.

The findings revealed that oregano essential oil displayed a remarkable ability to inhibit bacterial growth across a range of concentrations, confirming its strength as a potential treatment option. In contrast, while garlic and black pepper oils also showed some effectiveness, they were not as potent as oregano, particularly in their ability to hinder biofilm production—a significant problem in CDI cases, as biofilms protect bacteria from treatment.

With these results, it’s clear that essential oils, especially wild oregano oil, are promising adjunctive therapies for treating diarrhea resulting from CDI. Oregano stands out due to its broad-spectrum effectiveness against different C. difficile strains, making it an appealing option for those seeking natural treatment alternatives.
Read More
We explored the effectiveness of daily administration of oregano essential oil in preventing or lessening neonatal diarrhea in calves under 15 days old. In this study, we divided 91 newborn calves from three dairy farms into two groups. The "Eco" group received Greek oregano essential oil daily for the first 10 days of life, while the "Conts" group was left untreated as a control.

Over the duration of the study, we monitored the calves' health, specifically looking at diarrhea incidence and severity. Our findings revealed that calves treated with oregano essential oil had significantly lower average fecal scores and experienced fewer and less severe episodes of diarrhea compared to the untreated group.

This outcome suggests that oregano essential oil can effectively reduce the impact of naturally occurring diarrhea in young calves, especially when combined with proper hygiene practices. Thus, we can conclude that incorporating oregano into calf-rearing practices may provide a beneficial preventive measure against neonatal diarrhea syndrome.
Read More

Most Useful Reviews

1
Too harsh
13 people found this helpful
Too harsh on the digestive tract. After researching oregano oil for candida and UTI, I trusted the NOW brand. However, after one capsule with a meal, I felt as if I’d consumed battery acid. I am not typically sensitive to foods, but it was overwhelmingly harsh. The next morning included cramping and diarrhea that lasted most of the day. I had to drink Aloe Vera juice and eat some plain oatmeal to calm my stomach down. I cannot go through that again.
Read More
9
Helps alleviate diarrhoea
Oregano can protect against food poisoning and inhibit the growth of harmful bacteria from poor-quality food. Its decoctions and tinctures assist in treating diarrhoea, indigestion, and flatulence. It has been immensely helpful for me.
Read More
9
Eases stomach pain
Oregano oil capsules provide great relief from stomach aches and diarrhoea, effectively eliminating bacteria from the body.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8
  • All Researches
9.5
Oregano shows promise against diarrhea
We explored the potential of oregano, specifically Origanum majorana, to combat Blastocystis spp. cysts that are associated with gastrointestinal issues like diarrhea. In our investigation, we applied aqueous extracts of oregano and another herb, Foeniculum vulgare, to assess their efficacy in vitro.

By measuring the viability of human Peripheral Blood Mononuclear Cells and observing the response of isolated Blastocystis cysts to various concentrations of the herbal extracts, we aimed to uncover their anti-parasitic properties. Our results revealed that oregano extract at higher doses exhibited impressive effectiveness, achieving up to 100% efficacy after 72 hours, which was comparable to a standard drug used for treatment.

In contrast, while Foeniculum vulgare also showed some benefit, its efficacy was noticeably lower, reaching just 70.7% after the same duration. Both herbs featured high levels of beneficial compounds, including phenolic and flavonoid components, known for their antioxidant properties. This discovery paints a hopeful picture for using oregano as a natural remedy for managing diarrhea caused by these specific parasites.
Read More
9
Oregano oil effective against CDI
We explored the potential of essential oils from spice herbs, particularly oregano, in managing Clostridioides difficile infections (CDI), which are known to cause severe diarrhea in hospitalized patients. This study focused on three types of essential oils—wild oregano, garlic, and black pepper—and their antibacterial properties against various C. difficile strains. Our goal was to assess how effectively these oils could combat bacterial growth and inhibit biofilm formation under laboratory conditions.

The findings revealed that oregano essential oil displayed a remarkable ability to inhibit bacterial growth across a range of concentrations, confirming its strength as a potential treatment option. In contrast, while garlic and black pepper oils also showed some effectiveness, they were not as potent as oregano, particularly in their ability to hinder biofilm production—a significant problem in CDI cases, as biofilms protect bacteria from treatment.

With these results, it’s clear that essential oils, especially wild oregano oil, are promising adjunctive therapies for treating diarrhea resulting from CDI. Oregano stands out due to its broad-spectrum effectiveness against different C. difficile strains, making it an appealing option for those seeking natural treatment alternatives.
Read More
9
Oregano oil aids lamb diarrhea treatment
We explored the impact of oregano oil, combined with vitamins A, D, and E, on treating bacterial enteritis in lambs, which often results in diarrhea. In our study, we worked with 60 Barki lambs, splitting them into various groups: some received antibiotics alone, while others received antibiotics alongside the vitamins or oregano oil.

Our findings revealed that oregano oil showed promising antibacterial properties, effectively combating the bacteria responsible for diarrhea. The inclusion of oregano oil and antioxidant vitamins not only helped in reducing the severity of the condition but also improved several key health indicators in the treated lambs.

Notably, treatments that combined antibiotics with either antioxidants or oregano resulted in more significant health improvements compared to those who received antibiotics alone. This suggests that using oregano oil alongside traditional treatment methods could enhance recovery from bacterial enteritis in lambs, potentially making it a valuable addition to treatment regimens.
Read More
9
Oregano extract aids diarrhea management
In our research, we set out to discover how the aqueous extract of Origanum majorana L., commonly known as oregano, could help combat the effects of acute infectious diarrhea. Our study focused on understanding the mechanisms behind diarrhea, such as imbalance in water secretion and absorption in the intestines, as well as relaxation of the intestinal smooth muscle.

We conducted experiments using sections of mouse intestines and rat smooth muscle to assess the effects of oregano extract. The results were promising: we found that the oregano extract effectively inhibited chloride secretion, which is often increased during diarrhea. This was achieved at specific concentrations, showcasing its potential to reduce fluid loss.

Moreover, we observed that oregano extract enhanced sodium absorption, which is crucial for maintaining proper fluid balance in the intestines. In addition, oregano extract demonstrated the ability to relax intestinal smooth muscles, which can help alleviate discomfort during episodes of diarrhea.

Overall, our study indicates that oregano does indeed have positive effects on the mechanisms involved in managing acute infectious diarrhea. It shows promise as a natural treatment option worth considering for those seeking relief.
Read More
We explored the effectiveness of daily administration of oregano essential oil in preventing or lessening neonatal diarrhea in calves under 15 days old. In this study, we divided 91 newborn calves from three dairy farms into two groups. The "Eco" group received Greek oregano essential oil daily for the first 10 days of life, while the "Conts" group was left untreated as a control.

Over the duration of the study, we monitored the calves' health, specifically looking at diarrhea incidence and severity. Our findings revealed that calves treated with oregano essential oil had significantly lower average fecal scores and experienced fewer and less severe episodes of diarrhea compared to the untreated group.

This outcome suggests that oregano essential oil can effectively reduce the impact of naturally occurring diarrhea in young calves, especially when combined with proper hygiene practices. Thus, we can conclude that incorporating oregano into calf-rearing practices may provide a beneficial preventive measure against neonatal diarrhea syndrome.
Read More

User Reviews

USERS' SCORE
Questionable
Based on 16 Reviews
5.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
1
Too harsh
13 people found this helpful
Too harsh on the digestive tract. After researching oregano oil for candida and UTI, I trusted the NOW brand. However, after one capsule with a meal, I felt as if I’d consumed battery acid. I am not typically sensitive to foods, but it was overwhelmingly harsh. The next morning included cramping and diarrhea that lasted most of the day. I had to drink Aloe Vera juice and eat some plain oatmeal to calm my stomach down. I cannot go through that again.
Read More
9
Helps alleviate diarrhoea
Oregano can protect against food poisoning and inhibit the growth of harmful bacteria from poor-quality food. Its decoctions and tinctures assist in treating diarrhoea, indigestion, and flatulence. It has been immensely helpful for me.
Read More
9
Eases stomach pain
Oregano oil capsules provide great relief from stomach aches and diarrhoea, effectively eliminating bacteria from the body.
Read More
0
Intense pain
33 people found this helpful
Diarrhea with severe anal burning. I usually have excellent results with other NOW supplements, but this one didn't agree with me. I suspect the added oils, particularly ginger, did not sit well. After taking it with a smoothie, I experienced bad diarrhea and excruciating anal burning. The pain was so intense it felt unbearable. As much as I love the brand, I'm hesitant to try this product again.
Read More
0
Caused sickness
2 people found this helpful
I do not recommend this product. It made me feel increasingly weak every day after consumption. I experienced diarrhoea almost daily as a result. I plan to throw it away.
Read More

Frequently Asked Questions

9
Immediate diarrhoea relief
Very good gel that has a strong smell, which I don't mind. When suffering from diarrhoea, I take one after a meal, and the effect is immediate. It possesses a good bactericidal effect.
7.5
SIBO improvement noted
12 people found this helpful
My SIBO returned after gastroenteritis, resulting in gas buildup. However, after consuming this before meals, I noticed significant improvement within about 4.5 days. I was mindful of low FODMAP foods. I will continue with additional herbal remedies as I still deal with diarrhoea.
0
Not suitable
This product caused me to have diarrhoea whenever I consumed it, so it was unsuitable for me.
9
Eases stomach pain
Oregano oil capsules provide great relief from stomach aches and diarrhoea, effectively eliminating bacteria from the body.
9
Helps alleviate diarrhoea
Oregano can protect against food poisoning and inhibit the growth of harmful bacteria from poor-quality food. Its decoctions and tinctures assist in treating diarrhoea, indigestion, and flatulence. It has been immensely helpful for me.
0
Severe side effects
Unfortunately, this did not help me at all. Immediately after taking the capsule, I experienced severe diarrhoea and felt quite unwell.
0
No benefits seen
1 people found this helpful
I stopped using oregano capsules due to experiencing heartburn and diarrhoea. Although marjoram oil is recognised for its advantages, it did not provide any benefit for me and may work better for others.
9
Potent for diarrhoea
It’s very potent and effective for treating diarrhoea on an empty stomach.
We explored the effectiveness of daily administration of oregano essential oil in preventing or lessening neonatal diarrhea in calves under 15 days old. In this study, we divided 91 newborn calves from three dairy farms into two groups. The "Eco" group received Greek oregano essential oil daily for the first 10 days of life, while the "Conts" group was left untreated as a control.

Over the duration of the study, we monitored the calves' health, specifically looking at diarrhea incidence and severity. Our findings revealed that calves treated with oregano essential oil had significantly lower average fecal scores and experienced fewer and less severe episodes of diarrhea compared to the untreated group.

This outcome suggests that oregano essential oil can effectively reduce the impact of naturally occurring diarrhea in young calves, especially when combined with proper hygiene practices. Thus, we can conclude that incorporating oregano into calf-rearing practices may provide a beneficial preventive measure against neonatal diarrhea syndrome.
9
Oregano oil effective against CDI
We explored the potential of essential oils from spice herbs, particularly oregano, in managing Clostridioides difficile infections (CDI), which are known to cause severe diarrhea in hospitalized patients. This study focused on three types of essential oils—wild oregano, garlic, and black pepper—and their antibacterial properties against various C. difficile strains. Our goal was to assess how effectively these oils could combat bacterial growth and inhibit biofilm formation under laboratory conditions.

The findings revealed that oregano essential oil displayed a remarkable ability to inhibit bacterial growth across a range of concentrations, confirming its strength as a potential treatment option. In contrast, while garlic and black pepper oils also showed some effectiveness, they were not as potent as oregano, particularly in their ability to hinder biofilm production—a significant problem in CDI cases, as biofilms protect bacteria from treatment.

With these results, it’s clear that essential oils, especially wild oregano oil, are promising adjunctive therapies for treating diarrhea resulting from CDI. Oregano stands out due to its broad-spectrum effectiveness against different C. difficile strains, making it an appealing option for those seeking natural treatment alternatives.
9
Oregano extract aids diarrhea management
In our research, we set out to discover how the aqueous extract of Origanum majorana L., commonly known as oregano, could help combat the effects of acute infectious diarrhea. Our study focused on understanding the mechanisms behind diarrhea, such as imbalance in water secretion and absorption in the intestines, as well as relaxation of the intestinal smooth muscle.

We conducted experiments using sections of mouse intestines and rat smooth muscle to assess the effects of oregano extract. The results were promising: we found that the oregano extract effectively inhibited chloride secretion, which is often increased during diarrhea. This was achieved at specific concentrations, showcasing its potential to reduce fluid loss.

Moreover, we observed that oregano extract enhanced sodium absorption, which is crucial for maintaining proper fluid balance in the intestines. In addition, oregano extract demonstrated the ability to relax intestinal smooth muscles, which can help alleviate discomfort during episodes of diarrhea.

Overall, our study indicates that oregano does indeed have positive effects on the mechanisms involved in managing acute infectious diarrhea. It shows promise as a natural treatment option worth considering for those seeking relief.
9.5
Oregano shows promise against diarrhea
We explored the potential of oregano, specifically Origanum majorana, to combat Blastocystis spp. cysts that are associated with gastrointestinal issues like diarrhea. In our investigation, we applied aqueous extracts of oregano and another herb, Foeniculum vulgare, to assess their efficacy in vitro.

By measuring the viability of human Peripheral Blood Mononuclear Cells and observing the response of isolated Blastocystis cysts to various concentrations of the herbal extracts, we aimed to uncover their anti-parasitic properties. Our results revealed that oregano extract at higher doses exhibited impressive effectiveness, achieving up to 100% efficacy after 72 hours, which was comparable to a standard drug used for treatment.

In contrast, while Foeniculum vulgare also showed some benefit, its efficacy was noticeably lower, reaching just 70.7% after the same duration. Both herbs featured high levels of beneficial compounds, including phenolic and flavonoid components, known for their antioxidant properties. This discovery paints a hopeful picture for using oregano as a natural remedy for managing diarrhea caused by these specific parasites.

References

  1. Ansari M, Kargar S, Eslami MA, Falahati R, Albenzio M, et al. Potential benefits of early-life supplementation of liquid feed with fennel (Foeniculum vulgare) seeds or oregano (Origanum vulgare) leaves on growth, health, and blood metabolites in Holstein dairy calves. J Dairy Sci. 2022;105:6639. doi:10.3168/jds.2022-21776
  2. Aleksić A, Stojanović-Radić Z, Harmanus C, Kuijper EJ, Stojanović P. In vitro anti-clostridial action and potential of the spice herbs essential oils to prevent biofilm formation of hypervirulent Clostridioides difficile strains isolated from hospitalized patients with CDI. Anaerobe. 2022;76:102604. doi:10.1016/j.anaerobe.2022.102604
  3. Cremonesi P, Biscarini F, Castiglioni B, Sgoifo CA, Compiani R, et al. Gut microbiome modifications over time when removing in-feed antibiotics from the prophylaxis of post-weaning diarrhea in piglets. PLoS One. 2022;17:e0262199. doi:10.1371/journal.pone.0262199
  4. Darwish AA, Fawzy M, Osman WA, El Ebissy EA. Clinicopathological and bacteriological studies on lamb bacterial enteritis and monitoring the oregano oil and vitamins A,D,E effect on its treatment. J Adv Vet Anim Res. 2021;8:291. doi:10.5455/javar.2021.h514
  5. Sioutas G, Evangelou K, Vlachavas A, Papadopoulos E. Deaths Due to Mixed Infections with , spp. and in an Industrial Rabbit Farm in Greece. Pathogens. 2021;10. doi:10.3390/pathogens10060756
  6. Makrane H, Aziz M, Mekhfi H, Ziyyat A, Legssyer A, et al. Origanum majorana L. extract exhibit positive cooperative effects on the main mechanisms involved in acute infectious diarrhea. J Ethnopharmacol. 2019;239:111503. doi:10.1016/j.jep.2018.09.005
  7. Méabed EMH, El-Sayed NM, Abou-Sreea AIB, Roby MHH. Chemical analysis of aqueous extracts of Origanum majorana and Foeniculum vulgare and their efficacy on Blastocystis spp. cysts. Phytomedicine. 2018;43:158. doi:10.1016/j.phymed.2018.04.017
  8. Gaur S, Kuhlenschmidt TB, Kuhlenschmidt MS, Andrade JE. Effect of oregano essential oil and carvacrol on Cryptosporidium parvum infectivity in HCT-8 cells. Parasitol Int. 2018;67:170. doi:10.1016/j.parint.2017.11.001
  9. Katsoulos PD, Karatzia MA, Dovas CI, Filioussis G, Papadopoulos E, et al. Evaluation of the in-field efficacy of oregano essential oil administration on the control of neonatal diarrhea syndrome in calves. Res Vet Sci. 2017;115:478. doi:10.1016/j.rvsc.2017.07.029
  10. Rufino-González Y, Ponce-Macotela M, González-Maciel A, Reynoso-Robles R, Jiménez-Estrada M, et al. In vitro activity of the F-6 fraction of oregano against Giardia intestinalis. Parasitology. 2012;139:434. doi:10.1017/S0031182011002162
  11. Papatsiros VG, Tzika ED, Papaioannou DS, Kyriakis SC, Tassis PD, et al. Effect of Origanum vulgaris and Allium sativum extracts for the control of proliferative enteropathy in weaning pigs. Pol J Vet Sci. 2009;12:407.
  12. Bampidis VA, Christodoulou V, Florou-Paneri P, Christaki E. Effect of dried oregano leaves versus neomycin in treating newborn calves with colibacillosis. J Vet Med A Physiol Pathol Clin Med. 2006;53:154.
  13. Manzanilla EG, Perez JF, Martin M, Kamel C, Baucells F, et al. Effect of plant extracts and formic acid on the intestinal equilibrium of early-weaned pigs. J Anim Sci. 2004;82:3210.
  14. Giannenas I, Florou-Paneri P, Papazahariadou M, Christaki E, Botsoglou NA, et al. Effect of dietary supplementation with oregano essential oil on performance of broilers after experimental infection with Eimeria tenella. Arch Tierernahr. 2003;57:99.
image