Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.5
USERS' SCORE
Good
Based on 10 Reviews
8.3
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin B-6 [from 50 mg Coenzyme Pyridoxal-5-Phosphate (P-5-P) Monohydrate]
33 mg
1941%
Magnesium (from Magnesium Bisglycinate) (TRAACS®)
25 mg
6%
Top Medical Research Studies
9
We evaluated the effects of various treatments for nausea during early pregnancy, focusing on pyridoxine, or vitamin B6. Analyzing 28 trials, we found that pyridoxine showed promise in reducing nausea severity for those with milder symptoms. While anti-emetic medications overall helped reduce nausea significantly, we noted that more information is needed on their side effects and impact on fetal outcomes. Nevertheless, pyridoxine stands out as a useful option, with no evidence linking it to adverse fetal effects.
Read More
9
Vitamin B6 reduces pregnancy nausea
We assessed various methods for treating nausea and vomiting during early pregnancy, finding that vitamin B6 (pyridoxine) shows promise in easing nausea severity. Our analysis included 28 randomized trials, with many differing in quality. Among milder nausea cases, treatments like antihistamines and pyridoxine emerged as effective. Although we found consistent data supporting anti-emetic medication overall, some newer treatments like P6 acupressure were inconclusive. Importantly, no significant fetal risks were reported from these interventions.
Read More
8
B6 pyridoxine effective for nausea
We observed that high-quality research on over-the-counter medications during pregnancy, particularly for nausea, is somewhat scarce. However, vitamin B6, or pyridoxine, stands out as a safe and effective treatment for nausea and vomiting in pregnant women. Alongside this, H1 antihistamines and ginger are also recommended.
Nonpharmacologic approaches are usually advised as a first step. This is crucial since the safety of both maternal and fetal health needs to be prioritized when exploring treatment options during pregnancy.
Nonpharmacologic approaches are usually advised as a first step. This is crucial since the safety of both maternal and fetal health needs to be prioritized when exploring treatment options during pregnancy.
Read More
Most Useful Reviews
10
Helpful for nausea
1 people found this helpful
Helpful for nausea I did some research and found that pregnant women use P5P for nausea, so I tried it, because even though I’m not pregnant, I struggle with nausea, and it really works!
Read More
9
Excellent for nausea
1 people found this helpful
Excellent product for those unable to take vitamin B6 due to nausea.
Read More
10
Helps with nausea
I was feeling really nauseous, and my doctor mentioned this product. It genuinely helped me feel better.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.5
- All Researches
9
Pyridoxine alleviates pregnancy nausea
We delved into the effects of pyridoxine, or Vitamin B6, on nausea and vomiting during pregnancy, a common concern for many expectant mothers. By examining various studies, we found that out of 18 selected, eight showed clear benefits from using pyridoxine alone.
Furthermore, six additional studies indicated positive results when pyridoxine was combined with other treatments. Overall, our findings suggest that pyridoxine supplementation can significantly alleviate nausea symptoms during pregnancy.
Furthermore, six additional studies indicated positive results when pyridoxine was combined with other treatments. Overall, our findings suggest that pyridoxine supplementation can significantly alleviate nausea symptoms during pregnancy.
Read More
9
We evaluated the effects of various treatments for nausea during early pregnancy, focusing on pyridoxine, or vitamin B6. Analyzing 28 trials, we found that pyridoxine showed promise in reducing nausea severity for those with milder symptoms. While anti-emetic medications overall helped reduce nausea significantly, we noted that more information is needed on their side effects and impact on fetal outcomes. Nevertheless, pyridoxine stands out as a useful option, with no evidence linking it to adverse fetal effects.
Read More
9
Vitamin B6 reduces pregnancy nausea
We assessed various methods for treating nausea and vomiting during early pregnancy, finding that vitamin B6 (pyridoxine) shows promise in easing nausea severity. Our analysis included 28 randomized trials, with many differing in quality. Among milder nausea cases, treatments like antihistamines and pyridoxine emerged as effective. Although we found consistent data supporting anti-emetic medication overall, some newer treatments like P6 acupressure were inconclusive. Importantly, no significant fetal risks were reported from these interventions.
Read More
9
We examined how well doxylamine and pyridoxine, known as Diclectin, help reduce nausea and vomiting during pregnancy. This condition impacts around 80% of pregnant women, making effective treatment crucial. Several randomized, controlled trials have demonstrated Diclectin's effectiveness, ensuring it is safe for use in this context. Our analysis aims to correct misconceptions about its safety, confirming it is a viable option for those struggling with pregnancy-related nausea.
Read More
8
B6 pyridoxine effective for nausea
We observed that high-quality research on over-the-counter medications during pregnancy, particularly for nausea, is somewhat scarce. However, vitamin B6, or pyridoxine, stands out as a safe and effective treatment for nausea and vomiting in pregnant women. Alongside this, H1 antihistamines and ginger are also recommended.
Nonpharmacologic approaches are usually advised as a first step. This is crucial since the safety of both maternal and fetal health needs to be prioritized when exploring treatment options during pregnancy.
Nonpharmacologic approaches are usually advised as a first step. This is crucial since the safety of both maternal and fetal health needs to be prioritized when exploring treatment options during pregnancy.
Read More
User Reviews
USERS' SCORE
Good
Based on 10 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
10
Helpful for nausea
1 people found this helpful
Helpful for nausea I did some research and found that pregnant women use P5P for nausea, so I tried it, because even though I’m not pregnant, I struggle with nausea, and it really works!
Read More
9
Excellent for nausea
1 people found this helpful
Excellent product for those unable to take vitamin B6 due to nausea.
Read More
10
Helps with nausea
I was feeling really nauseous, and my doctor mentioned this product. It genuinely helped me feel better.
Read More
9
Nausea reduced
Excellent! My nausea was reduced, and I felt various other health benefits.
Read More
7.5
Improves nausea
Good composition, fast delivery, and convenient packaging. After 10 days of taking it, I noticed benefits in energy and reduction of fatigue and nausea.
Read More
Frequently Asked Questions
7.5
Improves nausea
Good composition, fast delivery, and convenient packaging. After 10 days of taking it, I noticed benefits in energy and reduction of fatigue and nausea.
10
Helps with nausea
I was feeling really nauseous, and my doctor mentioned this product. It genuinely helped me feel better.
6
Alleviates nausea
I used this during pregnancy, as B6 can help alleviate nausea. It helped a little, but wasn’t a complete solution.
10
Helpful for nausea
1 people found this helpful
Helpful for nausea I did some research and found that pregnant women use P5P for nausea, so I tried it, because even though I’m not pregnant, I struggle with nausea, and it really works!
9
Excellent for nausea
1 people found this helpful
Excellent product for those unable to take vitamin B6 due to nausea.
9
Nausea reduced
Excellent! My nausea was reduced, and I felt various other health benefits.
6
Induces nausea
Not bad; I take it at night; it gives me slight drowsiness at 200mg and nausea at 300mg.
7
We explored the effectiveness of pyridoxine, or Vitamin B6, as a preventive measure against postoperative nausea and vomiting (PONV) in patients undergoing gynecological laparoscopic surgery. In this randomized controlled trial, participants received either pyridoxine or a placebo along with standard anti-nausea medications.
Our findings indicated that those in the pyridoxine group experienced a lower incidence of PONV. However, further research across multiple centers is essential to confirm these promising results and establish broader applicability for diverse patient populations.
Our findings indicated that those in the pyridoxine group experienced a lower incidence of PONV. However, further research across multiple centers is essential to confirm these promising results and establish broader applicability for diverse patient populations.
9
Vitamin B6 reduces pregnancy nausea
We assessed various methods for treating nausea and vomiting during early pregnancy, finding that vitamin B6 (pyridoxine) shows promise in easing nausea severity. Our analysis included 28 randomized trials, with many differing in quality. Among milder nausea cases, treatments like antihistamines and pyridoxine emerged as effective. Although we found consistent data supporting anti-emetic medication overall, some newer treatments like P6 acupressure were inconclusive. Importantly, no significant fetal risks were reported from these interventions.
8
We conducted a study assessing whether ginger can effectively treat nausea in pregnancy, similar to vitamin B6. In our research, we involved 291 women who were less than 16 weeks pregnant, comparing the effects of 1.05 g of ginger daily to 75 mg of vitamin B6 over three weeks.
The results showed that ginger and vitamin B6 were equally effective in reducing nausea, retching, and vomiting symptoms. This demonstrates that for those seeking relief during early pregnancy, both remedies can offer comparable benefits.
The results showed that ginger and vitamin B6 were equally effective in reducing nausea, retching, and vomiting symptoms. This demonstrates that for those seeking relief during early pregnancy, both remedies can offer comparable benefits.
9
We examined how well doxylamine and pyridoxine, known as Diclectin, help reduce nausea and vomiting during pregnancy. This condition impacts around 80% of pregnant women, making effective treatment crucial. Several randomized, controlled trials have demonstrated Diclectin's effectiveness, ensuring it is safe for use in this context. Our analysis aims to correct misconceptions about its safety, confirming it is a viable option for those struggling with pregnancy-related nausea.
4
We investigated the use of vitamin B6 as a common treatment for nausea and vomiting during pregnancy. There has been an ongoing discussion about how effective high doses of this vitamin actually are, and we wanted to shed light on this issue.
Through a systematic review of literature, we examined various studies, focusing on reports that highlighted the effects of high doses of vitamin B6 on pregnant women experiencing nausea. While we found that many women do turn to vitamin B6 to alleviate their symptoms, particularly during the challenging first trimester, the data also raised serious concerns about potential side effects.
A significant portion of the studies reviewed documented adverse reactions in women taking excessive amounts of vitamin B6. These included neurological symptoms such as burning sensations, tingling, and coordination problems. Alarmingly, we also noted a few cases of miscarriage and intrauterine demise among those studied.
Overall, while vitamin B6 is a widely used treatment for nausea during pregnancy, we must exercise caution. The risks associated with high doses cannot be overlooked, particularly when it comes to the health of both the mother and the developing fetus.
Through a systematic review of literature, we examined various studies, focusing on reports that highlighted the effects of high doses of vitamin B6 on pregnant women experiencing nausea. While we found that many women do turn to vitamin B6 to alleviate their symptoms, particularly during the challenging first trimester, the data also raised serious concerns about potential side effects.
A significant portion of the studies reviewed documented adverse reactions in women taking excessive amounts of vitamin B6. These included neurological symptoms such as burning sensations, tingling, and coordination problems. Alarmingly, we also noted a few cases of miscarriage and intrauterine demise among those studied.
Overall, while vitamin B6 is a widely used treatment for nausea during pregnancy, we must exercise caution. The risks associated with high doses cannot be overlooked, particularly when it comes to the health of both the mother and the developing fetus.
References
- Zhang Q, Ye X, Shi S, Zhou S, Ma D, et al. Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecological Laparoscopic Surgery: A Double-blind Randomized Controlled Trial. Anesthesiology. 2024. 10.1097/ALN.0000000000005354
- Powers EA, Tewell R, Bayard M. Over-the-Counter Medications in Pregnancy. Am Fam Physician. 2023;108:360.
- Jayawardena R, Majeed S, Sooriyaarachchi P, Abeywarne U, Ranaweera P. The effects of pyridoxine (vitamin B6) supplementation in nausea and vomiting during pregnancy: a systematic review and meta-analysis. Arch Gynecol Obstet. 2023;308:1075. 10.1007/s00404-023-06925-w
- Ostby SA, Smith HJ, Leath CA. Pyridoxine for prevention and treatment of PARP inhibitor induced nausea and vomiting. Gynecol Oncol Rep. 2019;29:123. 10.1016/j.gore.2019.07.005
- Khorasani F, Aryan H, Sobhi A, Aryan R, Abavi-Sani A, et al. A systematic review of the efficacy of alternative medicine in the treatment of nausea and vomiting of pregnancy. J Obstet Gynaecol. 2020;40:10. 10.1080/01443615.2019.1587392
- Sharifzadeh F, Kashanian M, Koohpayehzadeh J, Rezaian F, Sheikhansari N, et al. A comparison between the effects of ginger, pyridoxine (vitamin B6) and placebo for the treatment of the first trimester nausea and vomiting of pregnancy (NVP). J Matern Fetal Neonatal Med. 2018;31:2509. 10.1080/14767058.2017.1344965
- McParlin C, O'Donnell A, Robson SC, Beyer F, Moloney E, et al. Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review. JAMA. 2016;316:1392. 10.1001/jama.2016.14337
- Boelig RC, Barton SJ, Saccone G, Kelly AJ, Edwards SJ, et al. Interventions for treating hyperemesis gravidarum. Cochrane Database Syst Rev. 2016;2016:CD010607. 10.1002/14651858.CD010607.pub2
- Jewell D, Young G. WITHDRAWN: Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev. 2010;2010:CD000145. 10.1002/14651858.CD000145.pub2
- Smith C, Crowther C, Willson K, Hotham N, McMillian V. A randomized controlled trial of ginger to treat nausea and vomiting in pregnancy. Obstet Gynecol. 2004;103:639.
- Jewell D, Young G. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev. 2003.
- Boskovic R, Einarson A, Maltepe C, Wolpin J, Koren G. Diclectin therapy for nausea and vomiting of pregnancy: effects of optimal dosing. J Obstet Gynaecol Can. 2003;25:830.
- Jewell D, Young G. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev. 2002.
- Bishai R, Mazzotta P, Atanackovic G, Levichek Z, Pole M, et al. Critical appraisal of drug therapy for nausea and vomiting of pregnancy: II. Efficacy and safety of diclectin (doxylamine-B6). Can J Clin Pharmacol. 2000;7:138.
- Jewell D, Young G. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev. 2000.
- Boneva RS, Moore CA, Botto L, Wong LY, Erickson JD. Nausea during pregnancy and congenital heart defects: a population-based case-control study. Am J Epidemiol. 1999;149:717.
- He L, Fan Y, Hu Y, Tian C, Tian Y, et al. The potential hazards of high doses of vitamin B6 in treating nausea and vomiting in pregnancy: A systematic review. Int J Gynaecol Obstet. 2024. 10.1002/ijgo.16032
