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SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Potassium (from 310 mg Potassium Citrate)
99 mg
2%
Top Medical Research Studies
7
Benzbromarone activates potassium channels
A Novel Role of Uricosuric Agent Benzbromarone in BK Channel Activation and Reduction of Airway Smooth Muscle Contraction.
Relevant for asthma treatment
We explored the effects of benzbromarone, a medication traditionally used for treating gout, on airway smooth muscle cells. Our investigation revealed that this drug does more than just influence uric acid levels; it also activates large conductance calcium-activated potassium channels, known as BK channels.
Through our research, we observed that benzbromarone enhances potassium currents in a dose-dependent manner. This means that as we increase the concentration of the drug, we see a more significant activation of these channels. The findings suggest that benzbromarone not only helps to hyperpolarize the membrane of airway smooth muscle cells but also might lead to relaxation of these muscles, which is crucial for those with conditions like asthma.
Importantly, we noted a potential avenue for repurposing this existing drug in asthma treatment and other related pulmonary problems. While our findings are promising regarding the role of potassium channels in managing airway contractions, we should approach the idea of potassium as a standalone treatment for asthma with caution. The effects we observed were indirect, mediated through benzbromarone, rather than from potassium treatment alone.
Overall, this study sheds light on the exciting potential for new asthma treatments derived from known medications and how they may affect potassium channel activity in managing airway smooth muscle contraction.
Through our research, we observed that benzbromarone enhances potassium currents in a dose-dependent manner. This means that as we increase the concentration of the drug, we see a more significant activation of these channels. The findings suggest that benzbromarone not only helps to hyperpolarize the membrane of airway smooth muscle cells but also might lead to relaxation of these muscles, which is crucial for those with conditions like asthma.
Importantly, we noted a potential avenue for repurposing this existing drug in asthma treatment and other related pulmonary problems. While our findings are promising regarding the role of potassium channels in managing airway contractions, we should approach the idea of potassium as a standalone treatment for asthma with caution. The effects we observed were indirect, mediated through benzbromarone, rather than from potassium treatment alone.
Overall, this study sheds light on the exciting potential for new asthma treatments derived from known medications and how they may affect potassium channel activity in managing airway smooth muscle contraction.
Read More
8
Testosterone's impact on asthma relief
Testosterone Enhances K Currents and Airway Smooth Muscle Relaxation Induced by ATP and UTP through P2Y Receptors and Adenylyl Cyclase Pathway.
Limited focus on potassium treatment
We explored how potassium channels interact with testosterone to impact asthma symptoms. In our experiments, we examined tracheal tissues from young male guinea pigs treated with testosterone, comparing them to a control group without treatment. We found that testosterone enhanced the relaxation of airway smooth muscle induced by ATP and UTP, which are essential players in easing airway constriction.
By utilizing organ baths and observing K currents in tracheal myocytes, we noticed that testosterone significantly improved the effects of ATP and UTP on potassium channels, leading to increased muscle relaxation. However, it's important to note that blocking these potassium channels with specific inhibitors diminished the effect of testosterone, highlighting their crucial role.
While our findings show that testosterone upregulates potassium channels and enhances purinergic signaling, we must recognize that the study focused specifically on the interplay of testosterone rather than isolating potassium treatment's direct effect on asthma. Overall, testosterone might contribute positively to asthma management, particularly in young men, but the distinct effects of potassium as a treatment are still unclear.
By utilizing organ baths and observing K currents in tracheal myocytes, we noticed that testosterone significantly improved the effects of ATP and UTP on potassium channels, leading to increased muscle relaxation. However, it's important to note that blocking these potassium channels with specific inhibitors diminished the effect of testosterone, highlighting their crucial role.
While our findings show that testosterone upregulates potassium channels and enhances purinergic signaling, we must recognize that the study focused specifically on the interplay of testosterone rather than isolating potassium treatment's direct effect on asthma. Overall, testosterone might contribute positively to asthma management, particularly in young men, but the distinct effects of potassium as a treatment are still unclear.
Read More
3
Potassium's minor role in asthma
Hypokalemia Measurement and Management in Patients With Status Asthmaticus on Continuous Albuterol.
Limited relevance in potassium effects
We explored how potassium impacts asthma treatment in pediatric patients undergoing continuous albuterol therapy during episodes of status asthmaticus. This particular therapy is common in hospitals but can lead to low potassium levels, known as hypokalemia. Our study aimed to determine whether repeated potassium monitoring is necessary by examining how often treatment for hypokalemia actually occurred.
In our analysis of 185 children treated with continuous albuterol from 2017 to 2019, we paid attention to potassium levels and treatments. Each child received intravenous fluids that contained potassium to help maintain adequate levels. Despite conducting 420 laboratory tests on potassium — an average of about 2.7 tests per patient — we found that very few patients required additional treatment for hypokalemia aside from the potassium included in their fluids.
Our findings indicated that the duration of albuterol therapy or its initial dosage did not significantly correlate with the occurrence of low potassium levels. We treated potassium deficiencies only 13 times across the cohort. Thus, we suggest that the frequency of potassium testing may be excessive, and reducing these tests could alleviate unnecessary discomfort and healthcare costs for families without jeopardizing patient safety.
In our analysis of 185 children treated with continuous albuterol from 2017 to 2019, we paid attention to potassium levels and treatments. Each child received intravenous fluids that contained potassium to help maintain adequate levels. Despite conducting 420 laboratory tests on potassium — an average of about 2.7 tests per patient — we found that very few patients required additional treatment for hypokalemia aside from the potassium included in their fluids.
Our findings indicated that the duration of albuterol therapy or its initial dosage did not significantly correlate with the occurrence of low potassium levels. We treated potassium deficiencies only 13 times across the cohort. Thus, we suggest that the frequency of potassium testing may be excessive, and reducing these tests could alleviate unnecessary discomfort and healthcare costs for families without jeopardizing patient safety.
Read More
Most Useful Reviews
8.8
Improved comfort
I’ve been managing my asthma solely with homeopathy, but I've had persistent symptoms, particularly stronger discomfort the day before rain. Since I began drinking this, my symptoms have almost vanished. Eliminating some throat discomfort has made me feel much more at ease. As I have a severe swelling constitution, I intend to continue taking it.
Read More
9.5
Reduced swelling
There are no more delays. Previously, I was prone to swelling which exacerbated my asthma before my period. Since taking this daily, that issue has resolved, and I feel very comfortable.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6
8
Testosterone's impact on asthma relief
Testosterone Enhances K Currents and Airway Smooth Muscle Relaxation Induced by ATP and UTP through P2Y Receptors and Adenylyl Cyclase Pathway.
Limited focus on potassium treatment
We explored how potassium channels interact with testosterone to impact asthma symptoms. In our experiments, we examined tracheal tissues from young male guinea pigs treated with testosterone, comparing them to a control group without treatment. We found that testosterone enhanced the relaxation of airway smooth muscle induced by ATP and UTP, which are essential players in easing airway constriction.
By utilizing organ baths and observing K currents in tracheal myocytes, we noticed that testosterone significantly improved the effects of ATP and UTP on potassium channels, leading to increased muscle relaxation. However, it's important to note that blocking these potassium channels with specific inhibitors diminished the effect of testosterone, highlighting their crucial role.
While our findings show that testosterone upregulates potassium channels and enhances purinergic signaling, we must recognize that the study focused specifically on the interplay of testosterone rather than isolating potassium treatment's direct effect on asthma. Overall, testosterone might contribute positively to asthma management, particularly in young men, but the distinct effects of potassium as a treatment are still unclear.
By utilizing organ baths and observing K currents in tracheal myocytes, we noticed that testosterone significantly improved the effects of ATP and UTP on potassium channels, leading to increased muscle relaxation. However, it's important to note that blocking these potassium channels with specific inhibitors diminished the effect of testosterone, highlighting their crucial role.
While our findings show that testosterone upregulates potassium channels and enhances purinergic signaling, we must recognize that the study focused specifically on the interplay of testosterone rather than isolating potassium treatment's direct effect on asthma. Overall, testosterone might contribute positively to asthma management, particularly in young men, but the distinct effects of potassium as a treatment are still unclear.
Read More
7
Benzbromarone activates potassium channels
A Novel Role of Uricosuric Agent Benzbromarone in BK Channel Activation and Reduction of Airway Smooth Muscle Contraction.
Relevant for asthma treatment
We explored the effects of benzbromarone, a medication traditionally used for treating gout, on airway smooth muscle cells. Our investigation revealed that this drug does more than just influence uric acid levels; it also activates large conductance calcium-activated potassium channels, known as BK channels.
Through our research, we observed that benzbromarone enhances potassium currents in a dose-dependent manner. This means that as we increase the concentration of the drug, we see a more significant activation of these channels. The findings suggest that benzbromarone not only helps to hyperpolarize the membrane of airway smooth muscle cells but also might lead to relaxation of these muscles, which is crucial for those with conditions like asthma.
Importantly, we noted a potential avenue for repurposing this existing drug in asthma treatment and other related pulmonary problems. While our findings are promising regarding the role of potassium channels in managing airway contractions, we should approach the idea of potassium as a standalone treatment for asthma with caution. The effects we observed were indirect, mediated through benzbromarone, rather than from potassium treatment alone.
Overall, this study sheds light on the exciting potential for new asthma treatments derived from known medications and how they may affect potassium channel activity in managing airway smooth muscle contraction.
Through our research, we observed that benzbromarone enhances potassium currents in a dose-dependent manner. This means that as we increase the concentration of the drug, we see a more significant activation of these channels. The findings suggest that benzbromarone not only helps to hyperpolarize the membrane of airway smooth muscle cells but also might lead to relaxation of these muscles, which is crucial for those with conditions like asthma.
Importantly, we noted a potential avenue for repurposing this existing drug in asthma treatment and other related pulmonary problems. While our findings are promising regarding the role of potassium channels in managing airway contractions, we should approach the idea of potassium as a standalone treatment for asthma with caution. The effects we observed were indirect, mediated through benzbromarone, rather than from potassium treatment alone.
Overall, this study sheds light on the exciting potential for new asthma treatments derived from known medications and how they may affect potassium channel activity in managing airway smooth muscle contraction.
Read More
3
Potassium's minor role in asthma
Hypokalemia Measurement and Management in Patients With Status Asthmaticus on Continuous Albuterol.
Limited relevance in potassium effects
We explored how potassium impacts asthma treatment in pediatric patients undergoing continuous albuterol therapy during episodes of status asthmaticus. This particular therapy is common in hospitals but can lead to low potassium levels, known as hypokalemia. Our study aimed to determine whether repeated potassium monitoring is necessary by examining how often treatment for hypokalemia actually occurred.
In our analysis of 185 children treated with continuous albuterol from 2017 to 2019, we paid attention to potassium levels and treatments. Each child received intravenous fluids that contained potassium to help maintain adequate levels. Despite conducting 420 laboratory tests on potassium — an average of about 2.7 tests per patient — we found that very few patients required additional treatment for hypokalemia aside from the potassium included in their fluids.
Our findings indicated that the duration of albuterol therapy or its initial dosage did not significantly correlate with the occurrence of low potassium levels. We treated potassium deficiencies only 13 times across the cohort. Thus, we suggest that the frequency of potassium testing may be excessive, and reducing these tests could alleviate unnecessary discomfort and healthcare costs for families without jeopardizing patient safety.
In our analysis of 185 children treated with continuous albuterol from 2017 to 2019, we paid attention to potassium levels and treatments. Each child received intravenous fluids that contained potassium to help maintain adequate levels. Despite conducting 420 laboratory tests on potassium — an average of about 2.7 tests per patient — we found that very few patients required additional treatment for hypokalemia aside from the potassium included in their fluids.
Our findings indicated that the duration of albuterol therapy or its initial dosage did not significantly correlate with the occurrence of low potassium levels. We treated potassium deficiencies only 13 times across the cohort. Thus, we suggest that the frequency of potassium testing may be excessive, and reducing these tests could alleviate unnecessary discomfort and healthcare costs for families without jeopardizing patient safety.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Reduced swelling
There are no more delays. Previously, I was prone to swelling which exacerbated my asthma before my period. Since taking this daily, that issue has resolved, and I feel very comfortable.
8.8
Improved comfort
I’ve been managing my asthma solely with homeopathy, but I've had persistent symptoms, particularly stronger discomfort the day before rain. Since I began drinking this, my symptoms have almost vanished. Eliminating some throat discomfort has made me feel much more at ease. As I have a severe swelling constitution, I intend to continue taking it.
Read More
