Overview

SCIENTIFIC SCORE
Questionable
Based on 7 Researches
5.9
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.8
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Iodine (from Potassium Iodide)
225 mcg
150%
Sodium (from Sodium Alginate)
5 mg
<1%
Potassium (from Potassium Chloride and Iodide)
99 mg
2%
Sodium Alginate
100 mg

Top Medical Research Studies

8
Potassium may moderately affect migraines
We explored the potential connection between dietary potassium intake and the occurrence of severe headaches or migraines. Utilizing data from over 10,000 US adults gathered through a national health survey from 1999 to 2004, we conducted a thorough analysis.

While we found that higher potassium intake was linked to a lower likelihood of migraines, the relationship appeared to be L-shaped, suggesting that there might be an optimal level of intake rather than a straightforward benefit. There's no strong evidence that potassium dramatically decreases headache frequency, but it does seem to play a role worth noting.
Read More
9.5
Potassium channel influence on migraines
We assessed whether levcromakalim, a potassium channel opener, influences migraine attacks in individuals already treated with erenumab. Conducted as a double-blind, placebo-controlled trial, our findings show that a significant number of participants reported migraines after receiving levcromakalim compared to placebo.

Specifically, 88% experienced migraine attacks following levcromakalim, vs. just 12% after the placebo. The study suggests that potassium channel activation may trigger migraine attacks independently of certain receptors typically associated with migraines.
Read More
We aimed to see if levcromakalim, a potassium channel opener, could trigger migraine-like headaches in individuals suffering from persistent post-traumatic headaches. In a robust, double-blind trial, participants received either levcromakalim or a placebo on different days and reported their headache experiences.

Surprisingly, over half of those receiving levcromakalim noted migraine-like headaches, marking a significant difference compared to those who received the placebo. This suggests that potassium channels are crucial in these headaches and may pave the way for new treatments using potassium channel blockers.
Read More

Most Useful Reviews

9
Essential iodine
5 people found this helpful
Far superior to Iodomarin! If you don’t live near the coast or eat fish regularly, iodine is vital. Iodine deficiency indicates symptoms like headaches and fatigue. This supplement helps improve overall health. It’s important to take it after breakfast for better absorption.
Read More
9
Reduced headaches
1 people found this helpful
The quality and ingredients are excellent, with adequate amounts. This is especially beneficial for those dealing with potassium deficiency, which triggers recurring headaches. My experience has shown that it significantly reduced my headache symptoms.
Read More
10
Life saviour
This has been a life saver! It’s the only thing that effectively helps my daughter with her headaches.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 7 Researches
5.9
  • All Researches
9.5
Potassium channel influence on migraines
We assessed whether levcromakalim, a potassium channel opener, influences migraine attacks in individuals already treated with erenumab. Conducted as a double-blind, placebo-controlled trial, our findings show that a significant number of participants reported migraines after receiving levcromakalim compared to placebo.

Specifically, 88% experienced migraine attacks following levcromakalim, vs. just 12% after the placebo. The study suggests that potassium channel activation may trigger migraine attacks independently of certain receptors typically associated with migraines.
Read More
We aimed to see if levcromakalim, a potassium channel opener, could trigger migraine-like headaches in individuals suffering from persistent post-traumatic headaches. In a robust, double-blind trial, participants received either levcromakalim or a placebo on different days and reported their headache experiences.

Surprisingly, over half of those receiving levcromakalim noted migraine-like headaches, marking a significant difference compared to those who received the placebo. This suggests that potassium channels are crucial in these headaches and may pave the way for new treatments using potassium channel blockers.
Read More
8
Potassium may moderately affect migraines
We explored the potential connection between dietary potassium intake and the occurrence of severe headaches or migraines. Utilizing data from over 10,000 US adults gathered through a national health survey from 1999 to 2004, we conducted a thorough analysis.

While we found that higher potassium intake was linked to a lower likelihood of migraines, the relationship appeared to be L-shaped, suggesting that there might be an optimal level of intake rather than a straightforward benefit. There's no strong evidence that potassium dramatically decreases headache frequency, but it does seem to play a role worth noting.
Read More
We explored how BK channels might relate to persistent post-traumatic headaches by examining the effects of MaxiPost, a BK channel opener. In a carefully designed study, participants with PPTH received either MaxiPost or a placebo during two sessions, separated by a week.

We found that MaxiPost could induce migraine-like headaches in individuals with PPTH, highlighting a potential target for new headache treatments through BK channel blockade. Further research is necessary to understand this connection and its therapeutic implications.
Read More
7
Potassium channel activation may induce headaches
We explored whether opening potassium channels could trigger cluster headache attacks. In a trial involving 41 participants divided into different headache categories, we administered levcromakalim, a potassium channel opener, or a placebo on separate days.

Our findings were intriguing; 60% of those with episodic cluster headaches experienced attacks after levcromakalim, compared to just 10% with the placebo. For chronic headache patients, 29% reported attacks post-levcromakalim, while those in remission showed no significant effects.

These results suggest that activating potassium channels can induce headaches in certain groups, highlighting a possible new avenue for treatment strategies.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 11 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Essential iodine
5 people found this helpful
Far superior to Iodomarin! If you don’t live near the coast or eat fish regularly, iodine is vital. Iodine deficiency indicates symptoms like headaches and fatigue. This supplement helps improve overall health. It’s important to take it after breakfast for better absorption.
Read More
9
Reduced headaches
1 people found this helpful
The quality and ingredients are excellent, with adequate amounts. This is especially beneficial for those dealing with potassium deficiency, which triggers recurring headaches. My experience has shown that it significantly reduced my headache symptoms.
Read More
10
Life saviour
This has been a life saver! It’s the only thing that effectively helps my daughter with her headaches.
Read More
10
Headaches resolved
I feel fantastic; the headaches have disappeared, and my skin has improved significantly!
Read More
10
Headaches eliminated
I have been taking this potassium supplement alongside magnesium, and they work wonders: I feel less fatigued, my headaches have vanished, there are no muscle cramps at night, and my energy and mood have improved. I highly recommend it.
Read More

Frequently Asked Questions

9
Headaches gone
I purchased this for a relative who had been hospitalised due to potassium deficiency. The doctor recommended this supplement, and it seems to have had significant benefits; after a month of use, they no longer report headaches.
6
Consistent use
It’s a good idea to take this product consistently for a few months to improve headaches.
10
Headaches eliminated
I have been taking this potassium supplement alongside magnesium, and they work wonders: I feel less fatigued, my headaches have vanished, there are no muscle cramps at night, and my energy and mood have improved. I highly recommend it.
10
Life saviour
This has been a life saver! It’s the only thing that effectively helps my daughter with her headaches.
10
Headaches resolved
I feel fantastic; the headaches have disappeared, and my skin has improved significantly!
1
Strong headache
I experience a strong headache after using the supplement, even though I suffer from potassium deficiency.
9
Reduced headaches
1 people found this helpful
The quality and ingredients are excellent, with adequate amounts. This is especially beneficial for those dealing with potassium deficiency, which triggers recurring headaches. My experience has shown that it significantly reduced my headache symptoms.
1
Not recommended
3 people found this helpful
Don't purchase this product. I tried it several times, but it made me feel unwell with stomach pain, sweating, and a headache. Consequently, I decided to stop taking it. I wouldn't recommend it.
9.5
Potassium channel influence on migraines
We assessed whether levcromakalim, a potassium channel opener, influences migraine attacks in individuals already treated with erenumab. Conducted as a double-blind, placebo-controlled trial, our findings show that a significant number of participants reported migraines after receiving levcromakalim compared to placebo.

Specifically, 88% experienced migraine attacks following levcromakalim, vs. just 12% after the placebo. The study suggests that potassium channel activation may trigger migraine attacks independently of certain receptors typically associated with migraines.
7
Potassium channel activation may induce headaches
We explored whether opening potassium channels could trigger cluster headache attacks. In a trial involving 41 participants divided into different headache categories, we administered levcromakalim, a potassium channel opener, or a placebo on separate days.

Our findings were intriguing; 60% of those with episodic cluster headaches experienced attacks after levcromakalim, compared to just 10% with the placebo. For chronic headache patients, 29% reported attacks post-levcromakalim, while those in remission showed no significant effects.

These results suggest that activating potassium channels can induce headaches in certain groups, highlighting a possible new avenue for treatment strategies.
0
Potasium salt showed no headache relief
This large trial looked at whether swapping regular salt for a potassium-enriched version could help reduce headaches in people at risk for strokes or high blood pressure.

After monitoring nearly 21,000 participants over an average of 4.7 years, we found that those who used potassium salt did not experience fewer or less severe headaches compared to those who continued with regular salt.

In fact, headache reports were similar across both groups, indicating that potassium salt substitution might not be the solution for headache relief.

References

  1. Al-Khazali HM, Christensen RH, Dodick DW, Chaudhry BA, Melchior AG, et al. Hypersensitivity to BK channel opening in persistent post-traumatic headache. J Headache Pain. 2024;25:102. doi:10.1186/s10194-024-01808-0
  2. Kokoti L, Al-Karagholi MA, Zhuang ZA, Amirguliyev S, Amin FM, et al. Non-vascular ATP-sensitive potassium channel activation does not trigger migraine attacks: A randomized clinical trial. Cephalalgia. 2024;44:3331024241248211. doi:10.1177/03331024241248211
  3. Haghdoost F, Gnanenthiran SR, Shan S, Kaistha P, Huang L, et al. The effect of salt substitution on frequency and severity of headache: results from the SSaSS cluster-randomised controlled trial of 20,995 participants. Eur J Clin Nutr. 2024;78:401. doi:10.1038/s41430-024-01419-7
  4. Raffaelli B, Do TP, Chaudhry BA, Amin FM, Ashina H, et al. Activation of ATP-sensitive potassium channels triggers migraine attacks independent of calcitonin gene-related peptide receptors: a randomized placebo-controlled trial. Cephalalgia. 2024;44:3331024231222916. doi:10.1177/03331024231222916
  5. Al-Khazali HM, Deligianni CI, Pellesi L, Al-Karagholi MA, Ashina H, et al. Induction of cluster headache after opening of adenosine triphosphate-sensitive potassium channels: a randomized clinical trial. Pain. 2024;165:1289. doi:10.1097/j.pain.0000000000003130
  6. Al-Khazali HM, Christensen RH, Dodick DW, Chaudhry BA, Burstein R, et al. Hypersensitivity to opening of ATP-sensitive potassium channels in post-traumatic headache. Cephalalgia. 2023;43:3331024231210930. doi:10.1177/03331024231210930
  7. Xu L, Zhang C, Liu Y, Shang X, Huang D. Association between dietary potassium intake and severe headache or migraine in US adults: a population-based analysis. Front Nutr. 2023;10:1255468. doi:10.3389/fnut.2023.1255468
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