Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 19 Researches
8.4
USERS' SCORE
Good
Based on 415 Reviews
8
Supplement Facts
Serving Size:   2 Veg Capsules
Amount Per Serving
%DV
Quercetin
800 mg
**
Bromelain (2,400 GDU/g)
165 mg
**

Top Medical Research Studies

9
Quercetin may alleviate allergy symptoms
We conducted a study involving 66 Japanese adults suffering from allergy symptoms, focusing on the potential of a quercetin-containing supplement. Participants took either the supplement or a placebo daily for four weeks.

Notable results showed that those taking quercetin experienced significant improvements in allergy-related symptoms such as eye itching, sneezing, and nasal discharge. Additionally, their overall quality of life received a boost.

While there were minor side effects, the findings suggest that quercetin might be an effective option for managing certain allergy symptoms.
Read More
We explored how quercetin may help alleviate allergies by examining its impact on certain immune cells involved in allergic reactions. Using different types of mast cells, we observed that quercetin triggered the production of heme oxygenase-1 (HO-1), which plays a key role in this process.

Interestingly, when we inhibited HO-1, the protective effects of quercetin vanished, suggesting that the Nrf2-HO-1 pathway is crucial for its anti-allergic actions. Our findings strongly indicate that quercetin could be valuable in managing allergic responses.
Read More
9.5
We delved into the effects of quercetin on peanut-induced anaphylactic reactions using a rat model. The study involved sensitized Wistar rats divided into treatment and control groups. After four weeks of quercetin treatment, we observed a significant decrease in plasma histamine levels and anaphylactic responses.

Our results suggest that quercetin effectively mitigates reactions related to peanut allergies, highlighting its potential as an alternative medicine for these food sensitivities. This presents an exciting avenue for those seeking solutions beyond traditional palliative care.
Read More

Most Useful Reviews

7.5
Effective for allergies
526 people found this helpful
Excellent tool! Before ordering this drug, I read that Quercetin with Bromelain strengthens the immune system and helps with allergies. Since I started taking one capsule per day, my allergy symptoms have improved within a week. I'm looking forward to the ageing benefits too. Thank you for the excellent service!
Read More
10
Miracle for allergies
434 people found this helpful
I've tried many remedies for spring allergies over the past 10 years, but these capsules are the most effective! After a week of taking 2 capsules at night, I no longer experience tearing, dry cough, or breathing difficulties. They’ve transformed my experience.
Read More
9
Huge difference noted
281 people found this helpful
This is a miracle for my allergies! I suffer from chronic allergies year-round, yet this product has surpassed over 20 years of allergy shots and medications, all without side effects. While it’s not a complete cure, taking two capsules multiple times daily has made a significant positive impact. During peak allergy times, I can even take extra doses to alleviate symptoms throughout the day. I'd recommend it to anyone suffering from allergies, but do check with a doctor if you're on other medications.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 19 Researches
8.4
  • All Researches
9.5
We delved into the effects of quercetin on peanut-induced anaphylactic reactions using a rat model. The study involved sensitized Wistar rats divided into treatment and control groups. After four weeks of quercetin treatment, we observed a significant decrease in plasma histamine levels and anaphylactic responses.

Our results suggest that quercetin effectively mitigates reactions related to peanut allergies, highlighting its potential as an alternative medicine for these food sensitivities. This presents an exciting avenue for those seeking solutions beyond traditional palliative care.
Read More
The study looked into how plant-made influenza vaccines interact with the immune system, particularly concerning allergies. We followed 280 participants over six months, monitoring for allergic reactions and measuring specific antibodies.

While some subjects produced temporary IgG and occasionally IgE antibodies, no allergic symptoms were reported. Importantly, the study found these antibody responses were not tied to allergy worsening, indicating that these vaccines may be safe for those with known plant allergies.
Read More
9
Quercetin shows promise in allergies
We delved into the potential of quercetin as a therapeutic option for treating allergic rhinitis, a common condition affecting roughly 40% of the global population. This study utilized various in-silico approaches, such as network pharmacology and molecular docking, to identify compounds from traditional medicinal plants and assess their effectiveness.

Among the 241 compounds analyzed, quercetin stood out due to its strong binding affinities with important targets linked to inflammatory and immune pathways. Our assessments indicated that quercetin could interact effectively with key cytokines involved in allergic reactions, potentially reducing allergy symptoms.

While the study highlighted promising implications for quercetin, it did not isolate its effects from other examined compounds. Therefore, further experimental testing is needed to affirm its benefits and effectiveness in real-world allergy treatment situations.
Read More
We investigated how a specific leaf extract affects allergic inflammation in immune cell lines.

Our study revealed that this extract notably reduced the release of allergy-related chemicals like histamine. It also decreased inflammatory responses by limiting the activity of certain enzymes involved in inflammation.

The findings suggest that the active compounds in the extract, specifically quercetin and kaempferol, could offer therapeutic benefits in managing allergies.
Read More
9
Quercetin may alleviate allergy symptoms
We conducted a study involving 66 Japanese adults suffering from allergy symptoms, focusing on the potential of a quercetin-containing supplement. Participants took either the supplement or a placebo daily for four weeks.

Notable results showed that those taking quercetin experienced significant improvements in allergy-related symptoms such as eye itching, sneezing, and nasal discharge. Additionally, their overall quality of life received a boost.

While there were minor side effects, the findings suggest that quercetin might be an effective option for managing certain allergy symptoms.
Read More

User Reviews

USERS' SCORE
Good
Based on 415 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Effective for allergies
526 people found this helpful
Excellent tool! Before ordering this drug, I read that Quercetin with Bromelain strengthens the immune system and helps with allergies. Since I started taking one capsule per day, my allergy symptoms have improved within a week. I'm looking forward to the ageing benefits too. Thank you for the excellent service!
Read More
10
Miracle for allergies
434 people found this helpful
I've tried many remedies for spring allergies over the past 10 years, but these capsules are the most effective! After a week of taking 2 capsules at night, I no longer experience tearing, dry cough, or breathing difficulties. They’ve transformed my experience.
Read More
9
Huge difference noted
281 people found this helpful
This is a miracle for my allergies! I suffer from chronic allergies year-round, yet this product has surpassed over 20 years of allergy shots and medications, all without side effects. While it’s not a complete cure, taking two capsules multiple times daily has made a significant positive impact. During peak allergy times, I can even take extra doses to alleviate symptoms throughout the day. I'd recommend it to anyone suffering from allergies, but do check with a doctor if you're on other medications.
Read More
9
Remarkable health boost
193 people found this helpful
It may just be my elixir for good health. Nothing has helped me as much as Quercetin+Bromelain. I've suffered from allergies and asthma for years, but after taking this for 3 or 4 years, I've noticed a complete change. I no longer fall sick like I used to. It’s not a magic solution, but for me, the benefits are undeniable. I don't even take allergy pills anymore as long as I'm consistently using my Quercetin+Bromelain.
Read More
9
Assists with allergies
179 people found this helpful
My family uses this for seasonal allergies, particularly for my son’s ragweed allergy. It has been very effective in alleviating his symptoms.
Read More

Frequently Asked Questions

7.5
Effective for allergies
526 people found this helpful
Excellent tool! Before ordering this drug, I read that Quercetin with Bromelain strengthens the immune system and helps with allergies. Since I started taking one capsule per day, my allergy symptoms have improved within a week. I'm looking forward to the ageing benefits too. Thank you for the excellent service!
10
Miracle for allergies
434 people found this helpful
I've tried many remedies for spring allergies over the past 10 years, but these capsules are the most effective! After a week of taking 2 capsules at night, I no longer experience tearing, dry cough, or breathing difficulties. They’ve transformed my experience.
9
Reduced irritation
84 people found this helpful
This dietary supplement has been invaluable for my chronic allergies. After taking two capsules nightly for two weeks, my symptoms significantly improved, and I no longer experience eye or nose irritation. I highly recommend Quercetin for allergy relief.
9
Significant improvement
100 people found this helpful
I have suffered from spring allergies for many years and tried various remedies without success. Then I found this supplement and experienced my first symptom-free spring! I am thrilled and thankful for this product!
9
Less pain experienced
122 people found this helpful
We took quercetin to support our immune systems and noticed my mother's leg pain reduced. We decided to try it with bromelain for allergy relief. After two weeks, we experienced positive effects, including improved sleep and reduced sweating. I will continue to purchase this product.
8.5
Allergy management tool
35 people found this helpful
I bought this for my terrible allergies to wormwood and other herbs. I managed to live an entire month without any medications, though I combine it with nettle root extract. I took 2 capsules in the morning and 1 in the evening. This has been a life-changer for my allergies.
9
Aids asthma sufferers
36 people found this helpful
I find these capsules highly effective for my chest allergies (asthma). After a few days of taking them alongside my other medication, I noticed significant improvement without side effects, apart from a slight bright yellow tint to my urine. I strongly recommend using it if you suffer from asthma.
9
Effective for asthma
52 people found this helpful
Quercetin combined with Bromelain is the strongest remedy for allergies, including bronchial asthma in both adults and children. This powerful combination quickly cleanses and heals the sinuses, boosts the immune system, and normalises respiratory function. I’m delighted with the results I've experienced.
8
Eased allergy symptoms
142 people found this helpful
I decided to take quercetin for allergies, as well as an antioxidant. The capsules are pleasant-smelling and easy to swallow. After around a week, my allergies eased, digestion improved, and constipation vanished. Quercetin strengthens blood vessels and reduces blood clot risk; I'm feeling much better now.
9
Quercetin may alleviate allergy symptoms
We conducted a study involving 66 Japanese adults suffering from allergy symptoms, focusing on the potential of a quercetin-containing supplement. Participants took either the supplement or a placebo daily for four weeks.

Notable results showed that those taking quercetin experienced significant improvements in allergy-related symptoms such as eye itching, sneezing, and nasal discharge. Additionally, their overall quality of life received a boost.

While there were minor side effects, the findings suggest that quercetin might be an effective option for managing certain allergy symptoms.
9
Quercetin shows promise in allergies
We delved into the potential of quercetin as a therapeutic option for treating allergic rhinitis, a common condition affecting roughly 40% of the global population. This study utilized various in-silico approaches, such as network pharmacology and molecular docking, to identify compounds from traditional medicinal plants and assess their effectiveness.

Among the 241 compounds analyzed, quercetin stood out due to its strong binding affinities with important targets linked to inflammatory and immune pathways. Our assessments indicated that quercetin could interact effectively with key cytokines involved in allergic reactions, potentially reducing allergy symptoms.

While the study highlighted promising implications for quercetin, it did not isolate its effects from other examined compounds. Therefore, further experimental testing is needed to affirm its benefits and effectiveness in real-world allergy treatment situations.
We investigated how quercetin works alongside fucoidan to help manage allergies, particularly type I hypersensitivity like hay fever. Our findings showed that when quercetin was taken together with fucoidan, even lower amounts could still provide significant anti-allergic effects.

Interestingly, taking just 50 μg of quercetin in combination with fucoidan produced similar benefits as higher doses alone. This suggests that the combination of these ingredients could lessen the need for larger fucoidan servings while still being effective.

It seems we’ve found a promising food combination that enhances allergy relief!
7
Quercetin shows potential for allergies
We explored the potential benefits of quercetin and other dietary components in managing allergic reactions. Research indicates that quercetin may play a role in reducing symptoms of allergic rhinitis by suppressing inflammatory mediators from mast cells, essential players in allergic responses.

Our analysis highlighted that while quercetin shows promise, it’s one of several dietary factors needing further investigation, especially due to concerns about how well our bodies can use these nutrients. Continued research on improving their bioavailability is crucial for maximizing their effects on allergies.

References

  1. Islam KMT, Mahmud S. In-silico exploring pathway and mechanism-based therapeutics for allergic rhinitis: Network pharmacology, molecular docking, ADMET, quantum chemistry and machine learning based QSAR approaches. Comput Biol Med. 2025;187:109754. doi:10.1016/j.compbiomed.2025.109754
  2. Bunddulam P, Nakamura M, Zorig A, Hinata Y, Takasugi M, et al. Effects of Leaf Extract on Allergic Inflammation in Immune Cell Lines. Prev Nutr Food Sci. 2025;30:68. doi:10.3746/pnf.2025.30.1.68
  3. Kaag S, Lorentz A. Effects of Dietary Components on Mast Cells: Possible Use as Nutraceuticals for Allergies?. Cells. 2023;12. doi:10.3390/cells12222602
  4. Mizuno M, Fujioka A, Bitani S, Minato KI, Sakakibara H. Anti-Allergic Activity of Fucoidan Can Be Enhanced by Coexistence with Quercetin. Int J Mol Sci. 2022;23. doi:10.3390/ijms232012163
  5. Yamada S, Shirai M, Inaba Y, Takara T. Effects of repeated oral intake of a quercetin-containing supplement on allergic reaction: a randomized, placebo-controlled, double-blind parallel-group study. Eur Rev Med Pharmacol Sci. 2022;26:4331. doi:10.26355/eurrev_202206_29072
  6. Afify SM, Pali-Schöll I, Hufnagl K, Hofstetter G, El-Bassuoni MA, et al. Bovine Holo-Beta-Lactoglobulin Cross-Protects Against Pollen Allergies in an Innate Manner in BALB/c Mice: Potential Model for the Farm Effect. Front Immunol. 2021;12:611474. doi:10.3389/fimmu.2021.611474
  7. Ding Y, Che D, Li C, Cao J, Wang J, et al. Quercetin inhibits Mrgprx2-induced pseudo-allergic reaction via PLCγ-IP3R related Ca fluctuations. Int Immunopharmacol. 2019;66:185. doi:10.1016/j.intimp.2018.11.025
  8. Carbone ML, Lulli D, Passarelli F, Pastore S. Topical Plant Polyphenols Prevent Type I Interferon Signaling in the Skin and Suppress Contact Hypersensitivity. Int J Mol Sci. 2018;19. doi:10.3390/ijms19092652
  9. Takasugi M, Muta E, Yamada K, Arai H. A new method to evaluate anti-allergic effect of food component by measuring leukotriene B from a mouse mast cell line. Cytotechnology. 2018;70:177. doi:10.1007/s10616-017-0129-9
  10. Kim M, Lim SJ, Kang SW, Um BH, Nho CW. Aceriphyllum rossii extract and its active compounds, quercetin and kaempferol inhibit IgE-mediated mast cell activation and passive cutaneous anaphylaxis. J Agric Food Chem. 2014;62:3750. doi:10.1021/jf405486c
  11. Shishehbor F, Behroo L, Ghafouriyan Broujerdnia M, Namjoyan F, Latifi SM. Quercetin effectively quells peanut-induced anaphylactic reactions in the peanut sensitized rats. Iran J Allergy Asthma Immunol. 2010;9:27.
  12. Matsushima M, Takagi K, Ogawa M, Hirose E, Ota Y, et al. Heme oxygenase-1 mediates the anti-allergic actions of quercetin in rodent mast cells. Inflamm Res. 2009;58:705. doi:10.1007/s00011-009-0039-1
  13. Cruz EA, Da-Silva SA, Muzitano MF, Silva PM, Costa SS, et al. Immunomodulatory pretreatment with Kalanchoe pinnata extract and its quercitrin flavonoid effectively protects mice against fatal anaphylactic shock. Int Immunopharmacol. 2008;8:1616. doi:10.1016/j.intimp.2008.07.006
  14. Shaik YB, Castellani ML, Perrella A, Conti F, Salini V, et al. Role of quercetin (a natural herbal compound) in allergy and inflammation. J Biol Regul Homeost Agents. 2006;20:47.
  15. Rogerio AP, Kanashiro A, Fontanari C, da Silva EV, Lucisano-Valim YM, et al. Anti-inflammatory activity of quercetin and isoquercitrin in experimental murine allergic asthma. Inflamm Res. 2007;56:402.
  16. Abram DM, Fernandes LGR, Perez-Riverol A, Regina Brochetto-Braga M, Zollner RL. Cross-Reactive Carbohydrate Determinant in , and Venoms: Identification of Allergic Sensitization and Cross-Reactivity. Toxins (Basel). 2020;12. doi:10.3390/toxins12100649
  17. Ward BJ, Landry N, Trépanier S, Mercier G, Dargis M, et al. Human antibody response to N-glycans present on plant-made influenza virus-like particle (VLP) vaccines. Vaccine. 2014;32:6098. doi:10.1016/j.vaccine.2014.08.079
  18. Secor ER, Carson WF, Cloutier MM, Guernsey LA, Schramm CM, et al. Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease. Cell Immunol. 2005;237:68.
  19. Braun JM, Schneider B, Beuth HJ. Therapeutic use, efficiency and safety of the proteolytic pineapple enzyme Bromelain-POS in children with acute sinusitis in Germany. In Vivo. 2005;19:417.
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