Flavonoids reduce cold incidenceEffect of Flavonoids on Upper Respiratory Tract Infections and Immune Function: A Systematic Review and Meta-Analysis.
Review highlights flavonoid effectiveness
We explored the role of flavonoid compounds, like quercetin, in reducing the frequency and severity of upper respiratory tract infections (URTIs) in healthy adults. An in-depth review of 14 studies showed that flavonoid supplementation notably reduced the incidence of URTIs by 33% and sick days by 40%.
However, we noted that changes in immune markers were minimal, indicating that while there are advantages in reducing infections, the immune response may not be significantly affected.
Read More
We investigated whether quercetin, a natural plant compound, could help combat common cold caused by rhinovirus (RV). In our study, quercetin reduced RV replication and inflammation in airway cells both in laboratory settings and in mice. When given before or after infection, quercetin limited the virus's ability to replicate and decreased harmful immune responses.
While our findings are promising, indicating that quercetin acts at various points in the virus's lifecycle, we recognize the need for further research to solidify its effectiveness in treating or preventing common colds.
Read More
Quercetin's antiviral potential confirmedQuercetin-3-Methyl Ether Induces Early Apoptosis to Overcome HRV1B Immune Evasion, Suppress Viral Replication, and Mitigate Inflammatory Pathogenesis.
Promising antiviral treatment explored
We explored the effects of quercetin-3-methyl ether, a natural flavonoid, on the common cold virus, specifically human rhinovirus 1B (HRV1B).
In our study, we found that this compound not only inhibited the virus's replication in human cells but also targeted the early stages of infection.
Additionally, quercetin enhanced early cell death to help combat the virus's immune evasion tactics.
While our findings highlight its potential as a new antiviral agent, further research is necessary to confirm its effectiveness in broader treatments.
Read More
Quercetin shows promise against virusesEffectiveness of supplementation with quercetin-type flavonols for treatment of viral lower respiratory tract infections: Systematic review and meta-analysis of preclinical studies.
High relevance for respiratory infections
We explored the effectiveness of quercetin-type flavonols in combating viral lower respiratory infections through a systematic review of 11 preclinical studies.
Our findings highlighted quercetin's impressive antiviral activity, showing lower mortality rates and reduced viral loads in infected animals.
Moreover, quercetin appeared to alleviate inflammation and mucus production, suggesting a multifaceted benefit for respiratory health. Overall, quercetin could be a promising option for those facing respiratory viral challenges.
Read More
We investigated how quercetin 7-glucoside (Q7G), sourced from Lagerstroemia speciosa, affects human rhinovirus 2 (HRV2), a leading cause of the common cold. Utilizing a method to reduce cytopathic effects, we found that Q7G significantly reduced HRV2 replication by blocking the virus's early infection stage.
Interestingly, compared to ribavirin, a known antiviral, Q7G showed stronger efficacy, suggesting its potential as a treatment for HRV2. While these results are promising, further research is needed to assess the practicality of using Q7G in common cold therapies.
Read More