Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.5
USERS' SCORE
Medium or Average
Based on 11 Reviews
6.6
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Quercetin
800 mg
**
Bromelain (2,400 GDU/g)
165 mg
**
Top Medical Research Studies
9
This study strategically divided 48 weaned piglets into four groups to evaluate how quercetin impacts diarrhea and growth. We noticed that piglets receiving higher doses of quercetin (500 and 750 mg/kg) had significantly fewer instances of diarrhea and an improved feed-to-gain ratio.
Additionally, quercetin improved the diversity of gut bacteria and regulated key inflammatory markers, suggesting it helps balance gut health. This shows promise for using quercetin as a means to reduce diarrhea and enhance growth performance in weaned piglets.
Additionally, quercetin improved the diversity of gut bacteria and regulated key inflammatory markers, suggesting it helps balance gut health. This shows promise for using quercetin as a means to reduce diarrhea and enhance growth performance in weaned piglets.
Read More
9.5
We aimed to explore the effectiveness of quercetin, a key polyphenol found in Psidium cattleianum Sabine, for treating diarrhea. Through various tests, including both in vivo and in vitro models, we observed that a defatted aqueous methanol extract (DAME) of the plant showed significant promise. Higher doses delayed diarrhea onset and reduced gastrointestinal transit, showcasing an impressive inhibition effect.
However, while quercetin and related compounds demonstrated binding to crucial receptors, further studies and clinical trials are needed to fully confirm its potential as a reliable treatment for diarrhea.
However, while quercetin and related compounds demonstrated binding to crucial receptors, further studies and clinical trials are needed to fully confirm its potential as a reliable treatment for diarrhea.
Read More
9
Quercetin shows significant antidiarrheal effects
We evaluated the antidiarrheal effects of leaf extract from an Ethiopian plant, known for its traditional medicinal use. Through a series of tests in mice, we found that the leaf extract significantly reduced diarrhea onset, fecal weight, and the frequency of defecation. Among the components tested, quercetin, extracted and identified from the plant, showed strong antidiarrheal activity as well. This supports the idea that quercetin plays a key role in alleviating diarrhea, contributing positively to the plant's traditional use in medicinal practices.
Read More
Most Useful Reviews
0
Headache and diarrhea
7 people found this helpful
I wanted to try these for my seasonal allergies, but they caused a severe headache and diarrhea, which prevented me from taking them long enough to determine if they would have helped. I've now switched to astaxanthin, which is effective without side effects.
Read More
0
Waste of money
My stomach hurts, and I am suffering from diarrhea and gas; it's difficult to digest. My stomach burns terribly, and obviously, this doesn't work for me. It feels like a total waste of money.
Read More
0
Skin outbreaks
After eating, I faced a recurrence of diarrhea and atopic dermatitis. My skin broke out again after taking this product, which suggests the ingredients might not suit me. Even after taking 400mg twice a day, I still experience diarrhea. I'm contemplating switching products.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.5
- All Researches
9.5
We aimed to explore the effectiveness of quercetin, a key polyphenol found in Psidium cattleianum Sabine, for treating diarrhea. Through various tests, including both in vivo and in vitro models, we observed that a defatted aqueous methanol extract (DAME) of the plant showed significant promise. Higher doses delayed diarrhea onset and reduced gastrointestinal transit, showcasing an impressive inhibition effect.
However, while quercetin and related compounds demonstrated binding to crucial receptors, further studies and clinical trials are needed to fully confirm its potential as a reliable treatment for diarrhea.
However, while quercetin and related compounds demonstrated binding to crucial receptors, further studies and clinical trials are needed to fully confirm its potential as a reliable treatment for diarrhea.
Read More
9
This study strategically divided 48 weaned piglets into four groups to evaluate how quercetin impacts diarrhea and growth. We noticed that piglets receiving higher doses of quercetin (500 and 750 mg/kg) had significantly fewer instances of diarrhea and an improved feed-to-gain ratio.
Additionally, quercetin improved the diversity of gut bacteria and regulated key inflammatory markers, suggesting it helps balance gut health. This shows promise for using quercetin as a means to reduce diarrhea and enhance growth performance in weaned piglets.
Additionally, quercetin improved the diversity of gut bacteria and regulated key inflammatory markers, suggesting it helps balance gut health. This shows promise for using quercetin as a means to reduce diarrhea and enhance growth performance in weaned piglets.
Read More
9
Quercetin shows significant antidiarrheal effects
We evaluated the antidiarrheal effects of leaf extract from an Ethiopian plant, known for its traditional medicinal use. Through a series of tests in mice, we found that the leaf extract significantly reduced diarrhea onset, fecal weight, and the frequency of defecation. Among the components tested, quercetin, extracted and identified from the plant, showed strong antidiarrheal activity as well. This supports the idea that quercetin plays a key role in alleviating diarrhea, contributing positively to the plant's traditional use in medicinal practices.
Read More
9
We investigated how quercetin, derived from a well-known medicinal plant, may help treat diarrhea. The research involved both laboratory tests and molecular analysis to assess its effects.
We found that quercetin and other compounds significantly reduced diarrhea in tests, especially in higher doses. The results indicated that the extracts exhibited effective antidiarrheal properties.
However, the the specific benefits of quercetin, compared to other components, were not clearly distinguished. This study supports the traditional use of these natural remedies for digestive issues.
We found that quercetin and other compounds significantly reduced diarrhea in tests, especially in higher doses. The results indicated that the extracts exhibited effective antidiarrheal properties.
However, the the specific benefits of quercetin, compared to other components, were not clearly distinguished. This study supports the traditional use of these natural remedies for digestive issues.
Read More
9
We investigated the antidiarrheal properties of extracts from two plant species, focusing on their quercetin content. In a controlled study using a castor oil-induced diarrhea model, we found that both extracts significantly delayed the onset of diarrhea and reduced intestinal fluid volume compared to the control group.
While both plant extracts demonstrated effectiveness, the one with higher quercetin levels showed even stronger results. The findings suggest that quercetin, along with other compounds, may play an important role in managing diarrhea.
While both plant extracts demonstrated effectiveness, the one with higher quercetin levels showed even stronger results. The findings suggest that quercetin, along with other compounds, may play an important role in managing diarrhea.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 11 Reviews
6.6
- All Reviews
- Positive Reviews
- Negative Reviews
0
Headache and diarrhea
7 people found this helpful
I wanted to try these for my seasonal allergies, but they caused a severe headache and diarrhea, which prevented me from taking them long enough to determine if they would have helped. I've now switched to astaxanthin, which is effective without side effects.
Read More
0
Waste of money
My stomach hurts, and I am suffering from diarrhea and gas; it's difficult to digest. My stomach burns terribly, and obviously, this doesn't work for me. It feels like a total waste of money.
Read More
0
Skin outbreaks
After eating, I faced a recurrence of diarrhea and atopic dermatitis. My skin broke out again after taking this product, which suggests the ingredients might not suit me. Even after taking 400mg twice a day, I still experience diarrhea. I'm contemplating switching products.
Read More
0
Consistent diarrhea issues
I experience diarrhea each time I eat it, along with stomach pain. Perhaps my stomach is sensitive?
Read More
9
Effective treatment
23 people found this helpful
I found this a good drug for respiratory diseases, including Covid. Initially, I couldn't take anything due to significant diarrhea and vomiting. However, once I started eating a little, I began taking it along with Zinc, Vitamin C, and D3. After the first dose, my temperature dropped remarkably, and the treatment lasted a week. I felt better during the allergy season, experiencing only mild symptoms. Overall, I was satisfied and might order a larger package!
Read More
Frequently Asked Questions
6
Adjust dosage
1 people found this helpful
After taking four capsules daily, my husband experienced severe diarrhea. He switched to two capsules a day, and he was fine. I take two capsules myself and do not have diarrhea, but I do notice frequent stools and uncomfortable intestinal cramps. It appears the medication may usually regulate stool, but it could be worth noting that some users might experience a laxative effect—starting with a lower dose is advisable.
9
Effective treatment
2 people found this helpful
This drug is good for respiratory illnesses and Covid. Initially, I couldn't eat anything due to considerable diarrhea and vomiting. However, after I started taking it with other supplements, my health significantly improved. My temperature decreased after the first dose, and by the end of a week, I felt much better. I managed allergies well during the fall and might order a larger quantity in the future.
9
Effective treatment
23 people found this helpful
I found this a good drug for respiratory diseases, including Covid. Initially, I couldn't take anything due to significant diarrhea and vomiting. However, once I started eating a little, I began taking it along with Zinc, Vitamin C, and D3. After the first dose, my temperature dropped remarkably, and the treatment lasted a week. I felt better during the allergy season, experiencing only mild symptoms. Overall, I was satisfied and might order a larger package!
7.5
Reduced dosage
8 people found this helpful
I took it for three days, and it caused severe diarrhea. I have since reduced my intake from four to two pills daily, and the diarrhea has cleared up, although I have yet to notice any difference with my sinuses. I will keep you posted on my progress.
0
Headache and diarrhea
7 people found this helpful
I wanted to try these for my seasonal allergies, but they caused a severe headache and diarrhea, which prevented me from taking them long enough to determine if they would have helped. I've now switched to astaxanthin, which is effective without side effects.
0
Negative intestinal reaction
I always trust the quality of this brand and decided to try quercetin as an antioxidant due to its popularity. While I can't articulate its positive effects on me, I experienced negative outcomes, notably that it did not suit my intestines and I developed diarrhea. Perhaps I have a sensitive gastrointestinal tract, and I must acknowledge that. Unfortunately, I can no longer continue taking this medication.
9
This study strategically divided 48 weaned piglets into four groups to evaluate how quercetin impacts diarrhea and growth. We noticed that piglets receiving higher doses of quercetin (500 and 750 mg/kg) had significantly fewer instances of diarrhea and an improved feed-to-gain ratio.
Additionally, quercetin improved the diversity of gut bacteria and regulated key inflammatory markers, suggesting it helps balance gut health. This shows promise for using quercetin as a means to reduce diarrhea and enhance growth performance in weaned piglets.
Additionally, quercetin improved the diversity of gut bacteria and regulated key inflammatory markers, suggesting it helps balance gut health. This shows promise for using quercetin as a means to reduce diarrhea and enhance growth performance in weaned piglets.
9
We looked into how quercetin, a natural antioxidant, could help combat rotavirus, a leading cause of watery diarrhea in young children. Our findings showed that quercetin reduced the production of rotavirus particles in infected cells and mice, confirming its potential as an antiviral agent. Its effectiveness was consistent across different rotavirus strains. Quercetin appears to work by inhibiting a specific viral activation pathway, suggesting that it could be a promising candidate for treating rotavirus-induced diarrhea.
8
We observed the effectiveness of quercetin in treating diarrhea caused by the porcine acute diarrhea syndrome coronavirus (SADS-CoV). Through carefully designed in vitro and in vivo experiments, quercetin was found to inhibit the virus and ease clinical symptoms in infected piglets.
This natural compound not only disrupted viral replication but also lessened inflammation in the intestines. Our findings suggest that quercetin could be a promising avenue for managing SADS-CoV-related diarrhea in pigs, which is crucial for reducing economic losses in the farming industry.
This natural compound not only disrupted viral replication but also lessened inflammation in the intestines. Our findings suggest that quercetin could be a promising avenue for managing SADS-CoV-related diarrhea in pigs, which is crucial for reducing economic losses in the farming industry.
9
We investigated how quercetin, derived from a well-known medicinal plant, may help treat diarrhea. The research involved both laboratory tests and molecular analysis to assess its effects.
We found that quercetin and other compounds significantly reduced diarrhea in tests, especially in higher doses. The results indicated that the extracts exhibited effective antidiarrheal properties.
However, the the specific benefits of quercetin, compared to other components, were not clearly distinguished. This study supports the traditional use of these natural remedies for digestive issues.
We found that quercetin and other compounds significantly reduced diarrhea in tests, especially in higher doses. The results indicated that the extracts exhibited effective antidiarrheal properties.
However, the the specific benefits of quercetin, compared to other components, were not clearly distinguished. This study supports the traditional use of these natural remedies for digestive issues.
9
We investigated the antidiarrheal properties of extracts from two plant species, focusing on their quercetin content. In a controlled study using a castor oil-induced diarrhea model, we found that both extracts significantly delayed the onset of diarrhea and reduced intestinal fluid volume compared to the control group.
While both plant extracts demonstrated effectiveness, the one with higher quercetin levels showed even stronger results. The findings suggest that quercetin, along with other compounds, may play an important role in managing diarrhea.
While both plant extracts demonstrated effectiveness, the one with higher quercetin levels showed even stronger results. The findings suggest that quercetin, along with other compounds, may play an important role in managing diarrhea.
References
- El-Deeb EM, Elsayed HE, Khazaal MT, El-Sayed EK, Ahmed AA, et al. Comprehensive assessment of the antidiarrheal properties of polyphenols from Psidium cattleianum Sabine's aerial parts. J Ethnopharmacol. 2025;346:119670. doi:10.1016/j.jep.2025.119670
- Mao Y, Yang Q, Liu J, Fu Y, Zhou S, et al. Quercetin Increases Growth Performance and Decreases Incidence of Diarrhea and Mechanism of Action in Weaned Piglets. Oxid Med Cell Longev. 2024;2024:5632260. doi:10.1155/2024/5632260
- Mogose B, Bisrat D, Asres K. Antidiarrheal Potential of the Leaf Extract of (Loes.) Sebsebe and Its Major Compound. J Trop Med. 2024;2024:5922487. doi:10.1155/2024/5922487
- Feng Y, Yi H, Zheng X, Liu X, Gong T, et al. Quercetin inhibition of porcine intestinal alpha coronavirus in vitro and in vivo. BMC Vet Res. 2024;20:134. doi:10.1186/s12917-024-03984-2
- Gong T, Wu D, Feng Y, Liu X, Gao Q, et al. Inhibitory effects of quercetin on porcine epidemic diarrhea virus in vitro and in vivo. Virology. 2024;589:109923. doi:10.1016/j.virol.2023.109923
- Ahmad I, Alotaibi BS, Malak N, Asad F, Ullah B, et al. Antidiarrheal Potential of : In Vivo and In Silico Approaches. Pharmaceuticals (Basel). 2023;16. doi:10.3390/ph16040489
- Mady MS, Ibrahim RR, El-Sayed EK, El-Shazly M, Chen LY, et al. UHPLC-MS profiles and antidiarrheal activity of münchh. and L. employing technique. Front Pharmacol. 2023;14:1120146. doi:10.3389/fphar.2023.1120146
- Wahid M, Saqib F, Akhtar S, Ali A, Tallei TE, et al. Mechanistic insights of Cucumis melo L. seeds for gastrointestinal muscle spasms through calcium signaling pathway-related gene regulation networks in WGCNA and in vitro, in vivo studies. Comput Biol Med. 2023;155:106596. doi:10.1016/j.compbiomed.2023.106596
- Banerjee S, Sarkar R, Mukherjee A, Miyoshi SI, Kitahara K, et al. Quercetin, a flavonoid, combats rotavirus infection by deactivating rotavirus-induced pro-survival NF-κB pathway. Front Microbiol. 2022;13:951716. doi:10.3389/fmicb.2022.951716
- Saqib F, Al-Huqail AA, Asma M, Chicea L, Hogea M, et al. Dose-dependent Spasmolytic, Bronchodilator, and Hypotensive Activities of L. Dose Response. 2022;20:15593258221079592. doi:10.1177/15593258221079592
- Xu B, Qin W, Xu Y, Yang W, Chen Y, et al. Dietary Quercetin Supplementation Attenuates Diarrhea and Intestinal Damage by Regulating Gut Microbiota in Weanling Piglets. Oxid Med Cell Longev. 2021;2021:6221012. doi:10.1155/2021/6221012
- Zhang Y, Yu F, Hao J, Nsabimana E, Wei Y, et al. Study on the Effective Material Basis and Mechanism of Traditional Chinese Medicine Prescription (QJC) Against Stress Diarrhea in Mice. Front Vet Sci. 2021;8:724491. doi:10.3389/fvets.2021.724491
- Mady MS, Elsayed HE, El-Sayed EK, Hussein AA, Ebrahim HY, et al. Polyphenolic profile and ethno pharmacological activities of Callistemonsubulatus (Cheel) Craven leaves cultivated in Egypt. J Ethnopharmacol. 2022;284:114698. doi:10.1016/j.jep.2021.114698
- Alam MM, Emon NU, Alam S, Rudra S, Akhter N, et al. Assessment of pharmacological activities of Lygodium microphyllum Cav. leaves in the management of pain, inflammation, pyrexia, diarrhea, and helminths: In vivo, in vitro and in silico approaches. Biomed Pharmacother. 2021;139:111644. doi:10.1016/j.biopha.2021.111644
