Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.8
USERS' SCORE
Good
Based on 38 Reviews
8.2
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Quercetin
800 mg
**
Bromelain (2,400 GDU/g)
165 mg
**
Top Medical Research Studies
9
We recently tested a quercetin-based supplement, Cysta-Q, on 22 patients with interstitial cystitis (IC) in an open-label trial. Over 4 weeks, participants took two capsules daily, and we assessed their symptoms before and after treatment.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
Read More
8
We sought to understand how quercetin could alleviate chronic pelvic pain associated with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) using a rat model. Over four weeks, rats received oral quercetin while measuring various blood and prostate health markers.
Our findings revealed that quercetin improved prostate health by reducing inflammation and enhancing antioxidant capacity. Specifically, it lowered levels of harmful inflammatory markers and suppressed certain signaling pathways known to contribute to pain. Overall, quercetin showed significant protective effects against CP/CPPS.
Our findings revealed that quercetin improved prostate health by reducing inflammation and enhancing antioxidant capacity. Specifically, it lowered levels of harmful inflammatory markers and suppressed certain signaling pathways known to contribute to pain. Overall, quercetin showed significant protective effects against CP/CPPS.
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7
We investigated how quercetin, a potential treatment for endometriosis-related pelvic pain, affects endometrial stromal cells. By using cells derived from menstrual effluent of both unaffected individuals and those with endometriosis, we observed quercetin's role in promoting decidualization, which is vital for embryo implantation.
Although the study shows promising mechanisms behind quercetin's effects, the direct benefits on reducing pelvic pain require further clinical exploration. Our findings suggest that while quercetin improves cellular responses, additional studies are needed to confirm its effectiveness as a treatment for chronic pelvic pain.
Although the study shows promising mechanisms behind quercetin's effects, the direct benefits on reducing pelvic pain require further clinical exploration. Our findings suggest that while quercetin improves cellular responses, additional studies are needed to confirm its effectiveness as a treatment for chronic pelvic pain.
Read More
Most Useful Reviews
9
Pain relief noted
262 people found this helpful
Excellent! After a week of taking it, I noticed that pain in my hands, back, and shoulders stopped during training.
Read More
9
Reduced cancer pain
25 people found this helpful
I chose this quercetin product because it was the leading seller. I’m using it along with other supplements to combat my advanced prostate cancer. Remarkably, the pain in my legs and feet is definitely decreasing, which is fantastic given my prognosis.
Read More
9
Pelvic pain resolution
9 people found this helpful
After experiencing severe pain during sexual activity for three years, which doctors could not diagnose, I decided to try this supplement for its anti-inflammatory benefits. Within a week of use, the pain vanished. I'd recommend it if you face similar issues.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.8
- All Researches
9
Quercetin shows promise for endometriosis pain
We explored the effectiveness of a combination treatment involving quercetin, curcumin, and acetylcysteine for easing pelvic pain in women with endometriosis. In this study, 33 women took the supplement daily for two months while we monitored their pain levels related to dysmenorrhea, pelvic pain, and dyspareunia.
The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
Read More
9
Quercetin alleviates pelvic pain
We explored the effects of Phyllanthus niruri extract and its isolated components, including quercetin, on hemorrhagic cystitis induced by cyclophosphamide in mice. The study involved treatment before and after inducing the condition and assessed pain, swelling, and bleeding.
We found that quercetin led to significant pain relief, while other compounds like gallic acid and rutin showed notable anti-inflammatory effects. Overall, the extract and its components proved beneficial in alleviating the treatment's side effects, suggesting potential therapeutic value.
We found that quercetin led to significant pain relief, while other compounds like gallic acid and rutin showed notable anti-inflammatory effects. Overall, the extract and its components proved beneficial in alleviating the treatment's side effects, suggesting potential therapeutic value.
Read More
9
We examined the effects of multimodal therapy on chronic pelvic pain using the UPOINT system. After 27 weeks, 100 patients receiving tailored treatments, including quercetin for organ-specific symptoms, showed notable improvement.
About 84% experienced significant symptom reduction, highlighting a median drop in pain scores from 11.5 to 6.1. While quercetin appeared beneficial, there was no guarantee that the number of symptoms predicted the outcome. Overall, this approach signifies a step forward in managing chronic pelvic pain effectively.
About 84% experienced significant symptom reduction, highlighting a median drop in pain scores from 11.5 to 6.1. While quercetin appeared beneficial, there was no guarantee that the number of symptoms predicted the outcome. Overall, this approach signifies a step forward in managing chronic pelvic pain effectively.
Read More
9
We recently tested a quercetin-based supplement, Cysta-Q, on 22 patients with interstitial cystitis (IC) in an open-label trial. Over 4 weeks, participants took two capsules daily, and we assessed their symptoms before and after treatment.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
Read More
9
We examined the potential of quercetin, a bioflavonoid, in alleviating pelvic pain in men with chronic prostatitis syndromes. In a randomized, double-blind trial involving 30 men, those taking quercetin experienced a notable reduction in symptoms compared to those on a placebo.
Specifically, 67% of men on quercetin showed a 25% improvement in symptoms, compared to just 20% in the placebo group. Even more encouraging, a follow-up with additional participants using a quercetin combination showed an impressive 82% improvement. Overall, quercetin is well tolerated and may significantly help for many facing chronic pelvic pain.
Specifically, 67% of men on quercetin showed a 25% improvement in symptoms, compared to just 20% in the placebo group. Even more encouraging, a follow-up with additional participants using a quercetin combination showed an impressive 82% improvement. Overall, quercetin is well tolerated and may significantly help for many facing chronic pelvic pain.
Read More
User Reviews
USERS' SCORE
Good
Based on 38 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Pain relief noted
262 people found this helpful
Excellent! After a week of taking it, I noticed that pain in my hands, back, and shoulders stopped during training.
Read More
9
Reduced cancer pain
25 people found this helpful
I chose this quercetin product because it was the leading seller. I’m using it along with other supplements to combat my advanced prostate cancer. Remarkably, the pain in my legs and feet is definitely decreasing, which is fantastic given my prognosis.
Read More
9
Pelvic pain resolution
9 people found this helpful
After experiencing severe pain during sexual activity for three years, which doctors could not diagnose, I decided to try this supplement for its anti-inflammatory benefits. Within a week of use, the pain vanished. I'd recommend it if you face similar issues.
Read More
9
Calms inflammation
3 people found this helpful
I have Mast Cell Activation Syndrome (MCAS), leading to constant allergy symptoms and pain. I ensure I take adequate quercetin alongside OTC antihistamines to manage histamine flares. This brand, with its high quercetin content, is perfect. I find when I take a dose during a histamine reaction, it drastically calms inflammation and alleviates symptoms. It is a powerful antioxidant that everyone can benefit from!
Read More
9
Pain from sinus relief
3 people found this helpful
I recently started taking this brand of Quercetin, having previously used another. It remarkably relieved my sinus pain within 30 minutes. I also combined it with D Mannose for UTI pain, and again, the relief was swift. Quercetin's anti-inflammatory benefits are impressive.
Read More
Frequently Asked Questions
9
Relieved pelvic pain
2 people found this helpful
Excellent for male pelvic floor pain! I had read about quercetin's benefits for male pelvic pain due to my hypertonic pelvic floor. After four days of use, my symptoms mostly disappeared. However, when I stopped taking it for a few days, the symptoms returned. I would regard this as a high-quality product, though I'm uncertain about Bromelain's effects on me. I initially bought this for the quercetin content.
9
Pelvic pain resolution
9 people found this helpful
After experiencing severe pain during sexual activity for three years, which doctors could not diagnose, I decided to try this supplement for its anti-inflammatory benefits. Within a week of use, the pain vanished. I'd recommend it if you face similar issues.
9
Pain relief noted
262 people found this helpful
Excellent! After a week of taking it, I noticed that pain in my hands, back, and shoulders stopped during training.
10
No bladder pain
2 people found this helpful
Awesome! This dietary supplement has changed my life. The combination of quercetin and bromelain is perfect for absorption. I use it for painful bladder syndrome, experiencing repeated cystitis without bacteria. Quercetin acts as an anti-inflammatory in the urinary system and prostate. Since using it for three weeks, I am no longer in pain. I am very pleased with the results.
9
Pain from sinus relief
3 people found this helpful
I recently started taking this brand of Quercetin, having previously used another. It remarkably relieved my sinus pain within 30 minutes. I also combined it with D Mannose for UTI pain, and again, the relief was swift. Quercetin's anti-inflammatory benefits are impressive.
9
Arthritis pain reduction
2 people found this helpful
I initially added quercetin due to Covid but plan to keep it as a staple because of its anti-inflammatory properties. Combined with other supplements, it has significantly alleviated my arthritis, leading to no pain in my hands. Consistent use has effectively contributed to the disappearance of pain.
9
Eased respiratory issues
5 people found this helpful
This product effectively alleviated respiratory conditions associated with flu and covid cough or chest pain from severe coughing. It truly works and reduces inflammation.
9
Neck pain relief
1 people found this helpful
I purchased this product based on reviews. I wasn't suffering from sinus issues but thought it might help if I developed any. What truly amazed me was the complete absence of neck pain that had plagued me for at least a year. After a few days on this product, the pain vanished. I couldn't be happier with this outcome.
9
Calms inflammation
3 people found this helpful
I have Mast Cell Activation Syndrome (MCAS), leading to constant allergy symptoms and pain. I ensure I take adequate quercetin alongside OTC antihistamines to manage histamine flares. This brand, with its high quercetin content, is perfect. I find when I take a dose during a histamine reaction, it drastically calms inflammation and alleviates symptoms. It is a powerful antioxidant that everyone can benefit from!
9
Reduced inflammation
5 people found this helpful
I can feel the inflammation subside. I took this for gastroesophageal reflux disease and my bronchi were in pain. As someone sensitive to physical sensations, I often notice various effects, but when I took this, I could clearly see the pain of the inflammation gradually diminishing within minutes. Until now, I thought medicine was the only way to suppress inflammation; I never realised a supplement could be so effective. I am now inclined to rely on supplements first rather than medication.
9
Quercetin shows promise for endometriosis pain
We explored the effectiveness of a combination treatment involving quercetin, curcumin, and acetylcysteine for easing pelvic pain in women with endometriosis. In this study, 33 women took the supplement daily for two months while we monitored their pain levels related to dysmenorrhea, pelvic pain, and dyspareunia.
The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
7
Ningmitai improves CP/CPPS symptoms
We investigated how Ningmitai capsules, which contain quercetin, could help with chronic pelvic pain and inflammation in a specific mouse model.
Our research showed that quercetin can lower pain-related signals and decrease inflammation by affecting immune cell activity.
Overall, treating with Ningmitai resulted in reduced pelvic pain and improved inflammation responses in these mice. Although this study shows promise, the effects may vary in real patients due to the complexity of the condition.
Our research showed that quercetin can lower pain-related signals and decrease inflammation by affecting immune cell activity.
Overall, treating with Ningmitai resulted in reduced pelvic pain and improved inflammation responses in these mice. Although this study shows promise, the effects may vary in real patients due to the complexity of the condition.
4
We investigated whether genetic variations could influence treatment success for chronic pelvic pain syndrome. Our research involved analyzing the DNA of 36 men with this condition and comparing their genetic markers to 252 control participants.
We found that those with a specific low IL-10 producing genotype were more common among patients experiencing chronic pelvic pain. Specifically, quercetin, an anti-inflammatory treatment, was less effective in patients with low TNF-alpha genotypes. This suggests the importance of genetic factors in determining how well quercetin works for relieving pelvic pain.
We found that those with a specific low IL-10 producing genotype were more common among patients experiencing chronic pelvic pain. Specifically, quercetin, an anti-inflammatory treatment, was less effective in patients with low TNF-alpha genotypes. This suggests the importance of genetic factors in determining how well quercetin works for relieving pelvic pain.
References
- Delenko J, Xue X, Chatterjee PK, Hyman N, Shih AJ, et al. Quercetin enhances decidualization through AKT-ERK-p53 signaling and supports a role for senescence in endometriosis. Reprod Biol Endocrinol. 2024;22:100. doi:10.1186/s12958-024-01265-z
- Liu H, Wang Z, Xie Q, Chi A, Li Y, et al. Ningmitai capsules have anti-inflammatory and pain-relieving effects in the chronic prostatitis/chronic pelvic pain syndrome mouse model through systemic immunity. Front Pharmacol. 2022;13:949316. doi:10.3389/fphar.2022.949316
- Fadin M, Nicoletti MC, Pellizzato M, Accardi M, Baietti MG, et al. Effectiveness of the integration of quercetin, turmeric, and N-acetylcysteine in reducing inflammation and pain associated with endometriosis. In-vitro and in-vivo studies. Minerva Ginecol. 2020;72:285. doi:10.23736/S0026-4784.20.04615-8
- Krakhotkin DV, Chernylovskyi VA, Bakurov EE, Sperl J. Evaluation of influence of the UPOINT-guided multimodal therapy in men with chronic prostatitis/chronic pelvic pain syndrome on dynamic values NIH-CPSI: a prospective, controlled, comparative study. Ther Adv Urol. 2019;11:1756287219857271. doi:10.1177/1756287219857271
- Maurizi A, De Luca F, Zanghi A, Manzi E, Leonardo C, et al. The role of nutraceutical medications in men with non bacterial chronic prostatitis and chronic pelvic pain syndrome: A prospective non blinded study utilizing flower pollen extracts versus bioflavonoids. Arch Ital Urol Androl. 2019;90:260. doi:10.4081/aiua.2018.4.260
- Park S, Lim W, Bazer FW, Whang KY, Song G. Quercetin inhibits proliferation of endometriosis regulating cyclin D1 and its target microRNAs in vitro and in vivo. J Nutr Biochem. 2019;63:87. doi:10.1016/j.jnutbio.2018.09.024
- Meng LQ, Yang FY, Wang MS, Shi BK, Chen DX, et al. Quercetin protects against chronic prostatitis in rat model through NF-κB and MAPK signaling pathways. Prostate. 2018;78:790. doi:10.1002/pros.23536
- Schiavi MC, Porpora MG, Vena F, Prata G, Sciuga V, et al. Orally Administered Combination of Hyaluronic Acid, Chondroitin Sulfate, Curcumin, and Quercetin in the Prevention of Postcoital Recurrent Urinary Tract Infections: Analysis of 98 Women in Reproductive Age After 6 Months of Treatment. Female Pelvic Med Reconstr Surg. 2019;25:309. doi:10.1097/SPV.0000000000000560
- Güney G, Kaya C, Oto G, Yıldırım S, Özdemir H, et al. Effects of quercetin and surgicel for preventing adhesions after gynecological surgery: A rat uterine horn model. J Obstet Gynaecol Res. 2017;43:179. doi:10.1111/jog.13185
- Boeira VT, Leite CE, Santos AA, Edelweiss MI, Calixto JB, et al. Effects of the hydroalcoholic extract of Phyllanthus niruri and its isolated compounds on cyclophosphamide-induced hemorrhagic cystitis in mouse. Naunyn Schmiedebergs Arch Pharmacol. 2011;384:265. doi:10.1007/s00210-011-0668-0
- Shoskes DA, Nickel JC, Kattan MW. Phenotypically directed multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome: a prospective study using UPOINT. Urology. 2010;75:1249. doi:10.1016/j.urology.2010.01.021
- Shoskes DA, Hakim L, Ghoniem G, Jackson CL. Long-term results of multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome. J Urol. 2003;169:1406.
- Shoskes DA, Albakri Q, Thomas K, Cook D. Cytokine polymorphisms in men with chronic prostatitis/chronic pelvic pain syndrome: association with diagnosis and treatment response. J Urol. 2002;168:331.
- Katske F, Shoskes DA, Sender M, Poliakin R, Gagliano K, et al. Treatment of interstitial cystitis with a quercetin supplement. Tech Urol. 2001;7:44.
- Shoskes DA, Zeitlin SI, Shahed A, Rajfer J. Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial. Urology. 1999;54:960.
