Last update
5/14/2025
Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8
USERS' SCORE
Good
Based on 16 Reviews
8.1
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Saccharomyces boulardii (10 Billion CFU)(Saccharomyces cerevisiae var. boulardii I-3799)
1,000 mg
**

Top Medical Research Studies

We investigated the role of Saccharomyces boulardii, a helpful probiotic, in combating Candida albicans, a troublesome pathogen for those with weakened immune systems.

By examining the effects on specific human intestinal cell lines, we found that both S. boulardii and its culture extract notably reduced C. albicans' ability to adhere to these cells.

Additionally, the extract lowered the production of harmful inflammatory markers, suggesting it may help manage inflammation linked to these infections. Overall, our findings highlight the potential of S. boulardii as a supportive treatment against candidiasis.
Read More
8
Saccharomyces boulardii reduces Candida translocation
We explored how orally administered Saccharomyces boulardii affects the translocation of Candida albicans from the gastrointestinal tract in mice. In this study, antibiotic-treated mice were challenged with C. albicans to simulate intestinal overgrowth.

We found that S. boulardii reduced the likelihood of C. albicans being detected in lymph nodes for healthy mice, but it did not lower its concentration there. However, in mice subjected to immunosuppression, S. boulardii significantly decreased both the incidence and the quantities of C. albicans translocation to various organs, showcasing its potential benefits in immunocompromised situations.
Read More
9
Saccharomyces boulardii's efficacy evaluated
We aimed to understand how Saccharomyces boulardii affects Candida albicans in a mouse model with chemically-induced colitis. By administering S. boulardii alongside C. albicans, we found that the yeast significantly reduced C. albicans colonization and inflammation related to the colitis.

Mice treated with S. boulardii showed lower levels of inflammatory markers and less severe symptoms than those that did not receive the yeast. Overall, our findings suggest that S. boulardii can help combat C. albicans and alleviate inflammation in this context.
Read More

Most Useful Reviews

9
Good effectiveness
2 people found this helpful
Excellent! This is the best probiotic for those suffering from candidiasis. I personally use it and have seen great improvement.
Read More
9
Works effectively
1 people found this helpful
They work splendidly for candidiasis! I take them in courses for 2-3 months and they have significantly helped with my symptoms.
Read More
9
Effective combination
An excellent product that I regularly keep in my medicine cabinet. In combination with female probiotics, it is effective for treating candidiasis.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8
  • All Researches
We explored how introducing probiotics in a pediatric intensive care unit (PICU) affected the prevalence of candidemia and candiduria in children receiving broad-spectrum antibiotics. In a retrospective study comparing two groups, we found that candidemia rates dropped significantly from 3.7% in the control group to 1.2% among those taking probiotics. Similarly, candiduria fell from 22% to 10.7%. These results suggest that probiotics may help reduce the risk of these fungal infections in critically ill children.
Read More
9
Saccharomyces boulardii's efficacy evaluated
We aimed to understand how Saccharomyces boulardii affects Candida albicans in a mouse model with chemically-induced colitis. By administering S. boulardii alongside C. albicans, we found that the yeast significantly reduced C. albicans colonization and inflammation related to the colitis.

Mice treated with S. boulardii showed lower levels of inflammatory markers and less severe symptoms than those that did not receive the yeast. Overall, our findings suggest that S. boulardii can help combat C. albicans and alleviate inflammation in this context.
Read More
Our investigation looked at how the probiotic yeast Saccharomyces boulardii can help combat candidiasis, particularly by reducing the virulence of Candida albicans. We found that S. boulardii secretes compounds that diminish C. albicans's ability to grow filaments, adhere, and form biofilms. Specifically, capric acid was identified as the main contributor to these inhibitory effects. While capric acid had a significant impact, it was less effective than the full yeast extract, which had additional factors that help suppress C. albicans adhesion.
Read More
We investigated the role of Saccharomyces boulardii, a helpful probiotic, in combating Candida albicans, a troublesome pathogen for those with weakened immune systems.

By examining the effects on specific human intestinal cell lines, we found that both S. boulardii and its culture extract notably reduced C. albicans' ability to adhere to these cells.

Additionally, the extract lowered the production of harmful inflammatory markers, suggesting it may help manage inflammation linked to these infections. Overall, our findings highlight the potential of S. boulardii as a supportive treatment against candidiasis.
Read More
8
Saccharomyces boulardii reduces Candida translocation
We explored how orally administered Saccharomyces boulardii affects the translocation of Candida albicans from the gastrointestinal tract in mice. In this study, antibiotic-treated mice were challenged with C. albicans to simulate intestinal overgrowth.

We found that S. boulardii reduced the likelihood of C. albicans being detected in lymph nodes for healthy mice, but it did not lower its concentration there. However, in mice subjected to immunosuppression, S. boulardii significantly decreased both the incidence and the quantities of C. albicans translocation to various organs, showcasing its potential benefits in immunocompromised situations.
Read More

User Reviews

USERS' SCORE
Good
Based on 16 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Good effectiveness
2 people found this helpful
Excellent! This is the best probiotic for those suffering from candidiasis. I personally use it and have seen great improvement.
Read More
9
Works effectively
1 people found this helpful
They work splendidly for candidiasis! I take them in courses for 2-3 months and they have significantly helped with my symptoms.
Read More
9
Effective combination
An excellent product that I regularly keep in my medicine cabinet. In combination with female probiotics, it is effective for treating candidiasis.
Read More
9
Improves condition
The drug significantly improves my condition regarding candidiasis. Its composition is excellent, devoid of fillers like magnesium stearate and silicon dioxide, which hinder absorption.
Read More
7.5
Helpful for candidiasis
4 people found this helpful
Good supplement for chronic candidiasis. This is quite potent. Maybe I overdid it by taking two capsules, one with lunch and one with dinner on the first day. Saccharomyces Boulardii is a yeast that eliminates candida, making it beneficial for candida overgrowth. Next time, I plan to start with one capsule daily and gradually increase the dose. I believe this supplement aids in alleviating chronic candidiasis.
Read More

Frequently Asked Questions

9
Works effectively
1 people found this helpful
They work splendidly for candidiasis! I take them in courses for 2-3 months and they have significantly helped with my symptoms.
9
Good effectiveness
2 people found this helpful
Excellent! This is the best probiotic for those suffering from candidiasis. I personally use it and have seen great improvement.
7.5
Helpful for candidiasis
4 people found this helpful
Good supplement for chronic candidiasis. This is quite potent. Maybe I overdid it by taking two capsules, one with lunch and one with dinner on the first day. Saccharomyces Boulardii is a yeast that eliminates candida, making it beneficial for candida overgrowth. Next time, I plan to start with one capsule daily and gradually increase the dose. I believe this supplement aids in alleviating chronic candidiasis.
9
Effective combination
An excellent product that I regularly keep in my medicine cabinet. In combination with female probiotics, it is effective for treating candidiasis.
9
Excellent quality supplement
This is an excellent, high-quality supplement that I highly recommend everyone should have in their first aid kit. It's beneficial when taken with antibiotics for treating candidiasis, scabies, and ringworm. The quality is simply top-notch.
7.5
Helped with candidiasis
I believe it has aided me in treating my candidiasis. I will continue using it, as this product appears to have a noticeable effect, particularly when taken in higher dosages, up to six daily.
9
Saccharomyces boulardii's efficacy evaluated
We aimed to understand how Saccharomyces boulardii affects Candida albicans in a mouse model with chemically-induced colitis. By administering S. boulardii alongside C. albicans, we found that the yeast significantly reduced C. albicans colonization and inflammation related to the colitis.

Mice treated with S. boulardii showed lower levels of inflammatory markers and less severe symptoms than those that did not receive the yeast. Overall, our findings suggest that S. boulardii can help combat C. albicans and alleviate inflammation in this context.
We investigated the role of Saccharomyces boulardii, a helpful probiotic, in combating Candida albicans, a troublesome pathogen for those with weakened immune systems.

By examining the effects on specific human intestinal cell lines, we found that both S. boulardii and its culture extract notably reduced C. albicans' ability to adhere to these cells.

Additionally, the extract lowered the production of harmful inflammatory markers, suggesting it may help manage inflammation linked to these infections. Overall, our findings highlight the potential of S. boulardii as a supportive treatment against candidiasis.
7
Biotherapeutic agents show potential
We reviewed placebo-controlled studies to see how biotherapeutic agents, like Saccharomyces boulardii, can help treat infections, including candidiasis. While many studies showed promising results in preventing antibiotic-related diarrhea and treating other infections, evidence specifically supporting the effectiveness of S. boulardii for vaginal candidiasis is limited. We found few adverse effects, but the sample sizes in studies were often small. Overall, it's a call to further research these microorganisms to potentially reduce our reliance on conventional antibiotics.

References

  1. Kumar S, Singhi S, Chakrabarti A, Bansal A, Jayashree M. Probiotic use and prevalence of candidemia and candiduria in a PICU. Pediatr Crit Care Med. 2013;14:e409. 10.1097/PCC.0b013e31829f5d88
  2. Murzyn A, Krasowska A, Stefanowicz P, Dziadkowiec D, Łukaszewicz M. Capric acid secreted by S. boulardii inhibits C. albicans filamentous growth, adhesion and biofilm formation. PLoS One. 2010;5:e12050. 10.1371/journal.pone.0012050
  3. Murzyn A, Krasowska A, Augustyniak D, Majkowska-Skrobek G, Łukaszewicz M, et al. The effect of Saccharomyces boulardii on Candida albicans-infected human intestinal cell lines Caco-2 and Intestin 407. FEMS Microbiol Lett. 2010;310:17. 10.1111/j.1574-6968.2010.02037.x
  4. Jawhara S, Poulain D. Saccharomyces boulardii decreases inflammation and intestinal colonization by Candida albicans in a mouse model of chemically-induced colitis. Med Mycol. 2007;45:691.
  5. Algin C, Sahin A, Kiraz N, Sahintürk V, Ihtiyar E. Effectiveness of bombesin and Saccharomyces boulardii against the translocation of Candida albicans in the digestive tract in immunosuppressed rats. Surg Today. 2005;35:869.
  6. Elmer GW, Surawicz CM, McFarland LV. Biotherapeutic agents. A neglected modality for the treatment and prevention of selected intestinal and vaginal infections. JAMA. 1996;275:870.
  7. Berg R, Bernasconi P, Fowler D, Gautreaux M. Inhibition of Candida albicans translocation from the gastrointestinal tract of mice by oral administration of Saccharomyces boulardii. J Infect Dis. 1993;168:1314.
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