Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.8
USERS' SCORE
Good
Based on 11 Reviews
8
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Calories
5
Total Carbohydrate
1 g
<1%**
Milk Thistle Extract (Silybum marianum)(Fruit/Seeds) (Standardized to 240 mg Silymarin Flavonoids - equivalent 80%)
300 mg
†
Turmeric (Curcuma longa) (Root)
700 mg
†
Top Medical Research Studies
9
We examined how silibinin, a compound found in milk thistle, affects allergic asthma in a mouse model. Our findings showed that silibinin significantly helped reduce airway inflammation and hyperresponsiveness, mainly by targeting the NF-κB pathway. This suggests that silibinin might offer protective benefits against allergic airway conditions by moderating inflammatory responses. While our research found promising results in mice, further studies are necessary to confirm its effectiveness in human asthma treatment.
Read More
9
We explored the effects of silibinin on allergies by studying its impact on antibody production and T-cell responses in mice sensitized to ovalbumin. The mice received either no treatment or different doses of silibinin before being exposed to the allergen.
Our findings revealed that silibinin significantly reduced the levels of IgE antibodies, which are responsible for allergic reactions. Conversely, it boosted levels of IgG(2a), an antibody that can help fight off allergens.
Silibinin also shifted the immune response towards a balance that favors Th1 cells, which may provide a beneficial effect against allergies.
Our findings revealed that silibinin significantly reduced the levels of IgE antibodies, which are responsible for allergic reactions. Conversely, it boosted levels of IgG(2a), an antibody that can help fight off allergens.
Silibinin also shifted the immune response towards a balance that favors Th1 cells, which may provide a beneficial effect against allergies.
Read More
8
Silybine shows potential against allergies
We observed the effects of silybine, a key component derived from Silybum marianum seeds, on allergic reactions in rats. The study revealed that silybine can lower blood pressure and inhibit the severe responses associated with anaphylactic shock.
Notably, it appears to stabilize mast cell membranes, preventing the release of histamine—a major player in allergic reactions. However, while these findings are promising, it remains unclear how these effects translate to humans suffering from allergies.
Notably, it appears to stabilize mast cell membranes, preventing the release of histamine—a major player in allergic reactions. However, while these findings are promising, it remains unclear how these effects translate to humans suffering from allergies.
Read More
Most Useful Reviews
9
Allergies disappeared
18 people found this helpful
Random allergies vanished after taking Silymarin alongside multivitamins. I had suffered from fatigue and skin rashes for years, but felt more energised and noticed my skin had returned to normal. I was surprised as dermatologists had said my issues were due to allergies from my sensitive skin. I'm pleased with the results and plan to continue with a second bottle.
Read More
9
Digestive aid
1 people found this helpful
This product helps with various allergies and aids digestion. It's now a staple in my purchases, and I recommend it.
Read More
9
No allergic reaction
I purchased Silymarin based on reviews. It did not cause allergies, and I noticed no adverse effects during use alongside another liver medication.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.8
- All Researches
9
We examined how silibinin, a compound found in milk thistle, affects allergic asthma in a mouse model. Our findings showed that silibinin significantly helped reduce airway inflammation and hyperresponsiveness, mainly by targeting the NF-κB pathway. This suggests that silibinin might offer protective benefits against allergic airway conditions by moderating inflammatory responses. While our research found promising results in mice, further studies are necessary to confirm its effectiveness in human asthma treatment.
Read More
9
We explored the effects of silibinin on allergies by studying its impact on antibody production and T-cell responses in mice sensitized to ovalbumin. The mice received either no treatment or different doses of silibinin before being exposed to the allergen.
Our findings revealed that silibinin significantly reduced the levels of IgE antibodies, which are responsible for allergic reactions. Conversely, it boosted levels of IgG(2a), an antibody that can help fight off allergens.
Silibinin also shifted the immune response towards a balance that favors Th1 cells, which may provide a beneficial effect against allergies.
Our findings revealed that silibinin significantly reduced the levels of IgE antibodies, which are responsible for allergic reactions. Conversely, it boosted levels of IgG(2a), an antibody that can help fight off allergens.
Silibinin also shifted the immune response towards a balance that favors Th1 cells, which may provide a beneficial effect against allergies.
Read More
9
We explored how silymarin, a natural compound from milk thistle, impacts UV light-induced immune suppression and oxidative stress. Testing on mice showed that silymarin treatment significantly enhanced the skin's immune response, reducing harmful leukocyte infiltration and lowering levels of immunosuppressive cytokines.
Notably, silymarin also decreased the production of reactive oxygen species and nitric oxide linked to skin damage. Our findings suggest that silymarin could be a promising candidate for developing skincare products or sunscreens aimed at preventing skin cancer.
Notably, silymarin also decreased the production of reactive oxygen species and nitric oxide linked to skin damage. Our findings suggest that silymarin could be a promising candidate for developing skincare products or sunscreens aimed at preventing skin cancer.
Read More
8
Silybine shows potential against allergies
We observed the effects of silybine, a key component derived from Silybum marianum seeds, on allergic reactions in rats. The study revealed that silybine can lower blood pressure and inhibit the severe responses associated with anaphylactic shock.
Notably, it appears to stabilize mast cell membranes, preventing the release of histamine—a major player in allergic reactions. However, while these findings are promising, it remains unclear how these effects translate to humans suffering from allergies.
Notably, it appears to stabilize mast cell membranes, preventing the release of histamine—a major player in allergic reactions. However, while these findings are promising, it remains unclear how these effects translate to humans suffering from allergies.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Allergies disappeared
18 people found this helpful
Random allergies vanished after taking Silymarin alongside multivitamins. I had suffered from fatigue and skin rashes for years, but felt more energised and noticed my skin had returned to normal. I was surprised as dermatologists had said my issues were due to allergies from my sensitive skin. I'm pleased with the results and plan to continue with a second bottle.
Read More
9
Digestive aid
1 people found this helpful
This product helps with various allergies and aids digestion. It's now a staple in my purchases, and I recommend it.
Read More
9
No allergic reaction
I purchased Silymarin based on reviews. It did not cause allergies, and I noticed no adverse effects during use alongside another liver medication.
Read More
7.5
Family health benefit
8 people found this helpful
I selected this product for the family due to its benefits for liver health and potential to alleviate allergies. Although I experienced an allergy from the turmeric, my spouse has seen positive improvements in his liver condition, feeling calmer and healthier after long-term use.
Read More
2
Diarrhoea relief
5 people found this helpful
I advise caution if you have allergies, are pregnant, or nursing. Those on insulin medication should consult their doctor, as milk thistle can lower glucose levels. After taking one capsule for the first time, I experienced diarrhoea for two days. Now, I use half a capsule mixed with family meals for a smaller dosage. Additionally, while I tested positive for COVID-19 with mild symptoms, I've noticed that my sore throat improved thanks to these capsules' anti-inflammatory properties.
Read More
Frequently Asked Questions
9
Allergies disappeared
18 people found this helpful
Random allergies vanished after taking Silymarin alongside multivitamins. I had suffered from fatigue and skin rashes for years, but felt more energised and noticed my skin had returned to normal. I was surprised as dermatologists had said my issues were due to allergies from my sensitive skin. I'm pleased with the results and plan to continue with a second bottle.
7.5
Skin rash relief
Excellent product for alleviating liver heaviness, food allergies, and skin rashes. However, if you have no gastrointestinal issues, you may not witness a significant effect.
9
Digestive aid
1 people found this helpful
This product helps with various allergies and aids digestion. It's now a staple in my purchases, and I recommend it.
7.5
Family health benefit
8 people found this helpful
I selected this product for the family due to its benefits for liver health and potential to alleviate allergies. Although I experienced an allergy from the turmeric, my spouse has seen positive improvements in his liver condition, feeling calmer and healthier after long-term use.
9
Allergy support
2 people found this helpful
This effective supplement contains natural ingredients. A friend struggling with food allergies found relief after using it, as it supports liver and gallbladder functions. It’s beneficial when taken in cycles and has greatly improved her wellbeing. Worth every penny!
7.5
Seasonal relief
1 people found this helpful
This product helps ease seasonal allergies, and I also incorporate quercetin and bee pollen for enhanced effects.
2
Diarrhoea relief
5 people found this helpful
I advise caution if you have allergies, are pregnant, or nursing. Those on insulin medication should consult their doctor, as milk thistle can lower glucose levels. After taking one capsule for the first time, I experienced diarrhoea for two days. Now, I use half a capsule mixed with family meals for a smaller dosage. Additionally, while I tested positive for COVID-19 with mild symptoms, I've noticed that my sore throat improved thanks to these capsules' anti-inflammatory properties.
9
We examined how silibinin, a compound found in milk thistle, affects allergic asthma in a mouse model. Our findings showed that silibinin significantly helped reduce airway inflammation and hyperresponsiveness, mainly by targeting the NF-κB pathway. This suggests that silibinin might offer protective benefits against allergic airway conditions by moderating inflammatory responses. While our research found promising results in mice, further studies are necessary to confirm its effectiveness in human asthma treatment.
9
We explored the effects of silibinin on allergies by studying its impact on antibody production and T-cell responses in mice sensitized to ovalbumin. The mice received either no treatment or different doses of silibinin before being exposed to the allergen.
Our findings revealed that silibinin significantly reduced the levels of IgE antibodies, which are responsible for allergic reactions. Conversely, it boosted levels of IgG(2a), an antibody that can help fight off allergens.
Silibinin also shifted the immune response towards a balance that favors Th1 cells, which may provide a beneficial effect against allergies.
Our findings revealed that silibinin significantly reduced the levels of IgE antibodies, which are responsible for allergic reactions. Conversely, it boosted levels of IgG(2a), an antibody that can help fight off allergens.
Silibinin also shifted the immune response towards a balance that favors Th1 cells, which may provide a beneficial effect against allergies.
8
Silybine shows potential against allergies
We observed the effects of silybine, a key component derived from Silybum marianum seeds, on allergic reactions in rats. The study revealed that silybine can lower blood pressure and inhibit the severe responses associated with anaphylactic shock.
Notably, it appears to stabilize mast cell membranes, preventing the release of histamine—a major player in allergic reactions. However, while these findings are promising, it remains unclear how these effects translate to humans suffering from allergies.
Notably, it appears to stabilize mast cell membranes, preventing the release of histamine—a major player in allergic reactions. However, while these findings are promising, it remains unclear how these effects translate to humans suffering from allergies.
References
- Choi YH, Jin GY, Guo HS, Piao HM, Li Lc, et al. Silibinin attenuates allergic airway inflammation in mice. Biochem Biophys Res Commun. 2012;427:450. doi:10.1016/j.bbrc.2012.07.112
- Kuo FH, Jan TR. Silibinin attenuates antigen-specific IgE production through the modulation of Th1/Th2 balance in ovalbumin-sensitized BALB/c mice. Phytomedicine. 2009;16:271. doi:10.1016/j.phymed.2008.07.006
- Katiyar SK. Treatment of silymarin, a plant flavonoid, prevents ultraviolet light-induced immune suppression and oxidative stress in mouse skin. Int J Oncol. 2002;21:1213.
- Lecomte J. [General pharmacologic properties of silybine and silymarine in the rat]. Arch Int Pharmacodyn Ther. 1975;214:165.
