Last update
4/18/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6
USERS' SCORE
Medium or Average
Based on 3 Reviews
6.7
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Calories
5
Total Carbohydrate
1 g
<1%**
Milk Thistle Extract (Silybum marianum)(Fruit/Seeds) (Standardized to 240 mg Silymarin Flavonoids - equivalent 80%)
300 mg
†
Turmeric (Curcuma longa) (Root)
700 mg
†
Top Medical Research Studies
8
Silybum marianum may reduce diarrhea
We analyzed how the food supplement Berberol®K, which includes silybin and berberine, affects diarrhea in diabetic patients struggling with dyslipidemia. In our study of 59 patients dealing with irritable bowel syndrome or diarrhea caused by metformin, we found that those taking Berberol®K experienced a notable reduction in diarrhea symptoms.
After six months, only five participants on the supplement reported diarrhea compared to 22 in the untreated group. This suggests that Silybum marianum may help alleviate diarrhea, making it a promising option for patients who are statin intolerant or struggling with gastrointestinal discomfort.
After six months, only five participants on the supplement reported diarrhea compared to 22 in the untreated group. This suggests that Silybum marianum may help alleviate diarrhea, making it a promising option for patients who are statin intolerant or struggling with gastrointestinal discomfort.
Read More
4
Silymarin shows limited effect on diarrhea
We examined the potential of silymarin in reducing chemotherapy-related diarrhea among other adverse reactions. Our review included 64 studies, which indicated that silymarin is generally safe and well-tolerated. While it demonstrates benefits for several conditions related to cancer treatment, its specific effect on diarrhea was less prominent, with only one study addressing this issue. Overall, we found that silymarin holds promise as a supportive treatment option, but more research is necessary to identify the best usage guidelines.
Read More
Most Useful Reviews
0
Not recommended IBD
5 people found this helpful
Neatly, after two weeks, I began experiencing violent abdominal pain, followed by severe diarrhoea. Once I stopped taking the capsules (two in the morning and two in the evening), everything calmed down. I strongly do not recommend this product to those with IBD!
Read More
2
Caused stomach pain
1 people found this helpful
Avoid if you have a weak stomach, as it contains turmeric. While NOW SILMARIN products are known to be beneficial for the liver, I noticed it upset someone's already bad bowel, causing diarrhoea. While I’m not sure it helps with fatigue, silymarin is recognised for its efficacy, though I haven't felt the benefits myself.
Read More
0
Severe diarrhoea
Excellent! I recognise this is a valuable product, but I had severe diarrhoea afterward. I believe the issue lies with my body and digestive system rather than the drug itself, its composition, or the manufacturer.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6
- All Researches
8
Silybum marianum may reduce diarrhea
We analyzed how the food supplement Berberol®K, which includes silybin and berberine, affects diarrhea in diabetic patients struggling with dyslipidemia. In our study of 59 patients dealing with irritable bowel syndrome or diarrhea caused by metformin, we found that those taking Berberol®K experienced a notable reduction in diarrhea symptoms.
After six months, only five participants on the supplement reported diarrhea compared to 22 in the untreated group. This suggests that Silybum marianum may help alleviate diarrhea, making it a promising option for patients who are statin intolerant or struggling with gastrointestinal discomfort.
After six months, only five participants on the supplement reported diarrhea compared to 22 in the untreated group. This suggests that Silybum marianum may help alleviate diarrhea, making it a promising option for patients who are statin intolerant or struggling with gastrointestinal discomfort.
Read More
4
Silymarin shows limited effect on diarrhea
We examined the potential of silymarin in reducing chemotherapy-related diarrhea among other adverse reactions. Our review included 64 studies, which indicated that silymarin is generally safe and well-tolerated. While it demonstrates benefits for several conditions related to cancer treatment, its specific effect on diarrhea was less prominent, with only one study addressing this issue. Overall, we found that silymarin holds promise as a supportive treatment option, but more research is necessary to identify the best usage guidelines.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 3 Reviews
6.7
- All Reviews
- Positive Reviews
- Negative Reviews
0
Not recommended IBD
5 people found this helpful
Neatly, after two weeks, I began experiencing violent abdominal pain, followed by severe diarrhoea. Once I stopped taking the capsules (two in the morning and two in the evening), everything calmed down. I strongly do not recommend this product to those with IBD!
Read More
2
Caused stomach pain
1 people found this helpful
Avoid if you have a weak stomach, as it contains turmeric. While NOW SILMARIN products are known to be beneficial for the liver, I noticed it upset someone's already bad bowel, causing diarrhoea. While I’m not sure it helps with fatigue, silymarin is recognised for its efficacy, though I haven't felt the benefits myself.
Read More
0
Severe diarrhoea
Excellent! I recognise this is a valuable product, but I had severe diarrhoea afterward. I believe the issue lies with my body and digestive system rather than the drug itself, its composition, or the manufacturer.
Read More
Frequently Asked Questions
0
Not recommended IBD
5 people found this helpful
Neatly, after two weeks, I began experiencing violent abdominal pain, followed by severe diarrhoea. Once I stopped taking the capsules (two in the morning and two in the evening), everything calmed down. I strongly do not recommend this product to those with IBD!
2
Caused stomach pain
1 people found this helpful
Avoid if you have a weak stomach, as it contains turmeric. While NOW SILMARIN products are known to be beneficial for the liver, I noticed it upset someone's already bad bowel, causing diarrhoea. While I’m not sure it helps with fatigue, silymarin is recognised for its efficacy, though I haven't felt the benefits myself.
4
Silymarin shows limited effect on diarrhea
We examined the potential of silymarin in reducing chemotherapy-related diarrhea among other adverse reactions. Our review included 64 studies, which indicated that silymarin is generally safe and well-tolerated. While it demonstrates benefits for several conditions related to cancer treatment, its specific effect on diarrhea was less prominent, with only one study addressing this issue. Overall, we found that silymarin holds promise as a supportive treatment option, but more research is necessary to identify the best usage guidelines.
8
Silybum marianum may reduce diarrhea
We analyzed how the food supplement Berberol®K, which includes silybin and berberine, affects diarrhea in diabetic patients struggling with dyslipidemia. In our study of 59 patients dealing with irritable bowel syndrome or diarrhea caused by metformin, we found that those taking Berberol®K experienced a notable reduction in diarrhea symptoms.
After six months, only five participants on the supplement reported diarrhea compared to 22 in the untreated group. This suggests that Silybum marianum may help alleviate diarrhea, making it a promising option for patients who are statin intolerant or struggling with gastrointestinal discomfort.
After six months, only five participants on the supplement reported diarrhea compared to 22 in the untreated group. This suggests that Silybum marianum may help alleviate diarrhea, making it a promising option for patients who are statin intolerant or struggling with gastrointestinal discomfort.
References
- Ghodousi M, Karbasforooshan H, Arabi L, Elyasi S. Silymarin as a preventive or therapeutic measure for chemotherapy and radiotherapy-induced adverse reactions: a comprehensive review of preclinical and clinical data. Eur J Clin Pharmacol. 2023;79:15. 10.1007/s00228-022-03434-8
- Di Pierro F, Putignano P, Villanova N. Retrospective analysis of the effects of a highly standardized mixture of Berberis aristata, Silybum marianum, and monacolins K and KA in diabetic patients with dyslipidemia. Acta Biomed. 2018;88:462. 10.23750/abm.v88i4.5851
