Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
USERS' SCORE
Good
Based on 18 Reviews
8.1
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Calories
5
Total Carbohydrate
1 g
<1%**
Milk Thistle Extract (Silybum marianum)(Fruit/Seeds) (Standardized to 240 mg Silymarin Flavonoids - equivalent 80%)
300 mg
†
Turmeric (Curcuma longa) (Root)
700 mg
†
Top Medical Research Studies
9
Silymarin positively influences cholesterol
We conducted a triple-blinded randomized clinical trial with 40 type 2 diabetes patients to see how silymarin impacts cholesterol and blood sugar levels. Over 45 days, participants received either silymarin or a placebo.
Our findings showed that those taking silymarin experienced significant improvements. They had lower fasting blood sugar, reduced triglycerides, and improved levels of good HDL cholesterol.
However, while the results are promising, further research is necessary to confirm these benefits for managing cholesterol in diabetes patients.
Our findings showed that those taking silymarin experienced significant improvements. They had lower fasting blood sugar, reduced triglycerides, and improved levels of good HDL cholesterol.
However, while the results are promising, further research is necessary to confirm these benefits for managing cholesterol in diabetes patients.
Read More
8
Silybum marianum reduces cholesterol effectively
We explored the impacts of Silybum marianum extract on broiler chickens’ health and performance. Chicks were divided into groups, with some receiving the extract in their diet while others did not.
Interestingly, we found that the group fed with Silybum marianum showed significant benefits, including lower cholesterol levels and better weight gain. However, the method of in ovo feeding did not show any notable effects on hatchability or initial weight.
Overall, incorporating Silybum marianum in their diet appears to help improve cholesterol levels and support overall growth in chickens.
Interestingly, we found that the group fed with Silybum marianum showed significant benefits, including lower cholesterol levels and better weight gain. However, the method of in ovo feeding did not show any notable effects on hatchability or initial weight.
Overall, incorporating Silybum marianum in their diet appears to help improve cholesterol levels and support overall growth in chickens.
Read More
9
We examined the effects of a polyherbal emulsion named F6-SMONSECCE on diabetic rats induced with alloxan. This formulation, crafted from various extracts, showed promising results in reducing blood sugar and cholesterol levels significantly.
Remarkably, we found reductions in total cholesterol and triglycerides, alongside improvements in insulin and HDL levels. The herbal treatment also promoted healing in the pancreas and kidneys, suggesting potential as a supportive remedy for diabetes and related conditions. However, further research is essential to fully understand its impact on human health.
Remarkably, we found reductions in total cholesterol and triglycerides, alongside improvements in insulin and HDL levels. The herbal treatment also promoted healing in the pancreas and kidneys, suggesting potential as a supportive remedy for diabetes and related conditions. However, further research is essential to fully understand its impact on human health.
Read More
Most Useful Reviews
7.5
Decreased liver enzymes
7 people found this helpful
I bought this for my mother undergoing chemotherapy due to high ASAT and ALAT levels. After using milk thistle alongside Chlorella, her liver support improved significantly, and her ASAT and ALAT levels dropped close to normal.
Read More
10
Liver function support
4 people found this helpful
I have been using Silymarin Milk Thistle Extract for years, and it's brilliant! My liver is in excellent condition, as confirmed by recent blood tests. I've tried both 150 mg and 300 mg doses, both of which protect my liver effectively. Highly recommended!
Read More
9
Bilirubin reduction
3 people found this helpful
I took this supplement for post-cycle therapy after hormonal treatments due to elevated bilirubin levels. I previously tried Heptral, which is more costly. After two months of this product, my tests returned to normal, so I can recommend it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
- All Researches
9
We examined the effects of a polyherbal emulsion named F6-SMONSECCE on diabetic rats induced with alloxan. This formulation, crafted from various extracts, showed promising results in reducing blood sugar and cholesterol levels significantly.
Remarkably, we found reductions in total cholesterol and triglycerides, alongside improvements in insulin and HDL levels. The herbal treatment also promoted healing in the pancreas and kidneys, suggesting potential as a supportive remedy for diabetes and related conditions. However, further research is essential to fully understand its impact on human health.
Remarkably, we found reductions in total cholesterol and triglycerides, alongside improvements in insulin and HDL levels. The herbal treatment also promoted healing in the pancreas and kidneys, suggesting potential as a supportive remedy for diabetes and related conditions. However, further research is essential to fully understand its impact on human health.
Read More
9
Silymarin positively influences cholesterol
We conducted a triple-blinded randomized clinical trial with 40 type 2 diabetes patients to see how silymarin impacts cholesterol and blood sugar levels. Over 45 days, participants received either silymarin or a placebo.
Our findings showed that those taking silymarin experienced significant improvements. They had lower fasting blood sugar, reduced triglycerides, and improved levels of good HDL cholesterol.
However, while the results are promising, further research is necessary to confirm these benefits for managing cholesterol in diabetes patients.
Our findings showed that those taking silymarin experienced significant improvements. They had lower fasting blood sugar, reduced triglycerides, and improved levels of good HDL cholesterol.
However, while the results are promising, further research is necessary to confirm these benefits for managing cholesterol in diabetes patients.
Read More
9
Milk thistle reduces cholesterol levels
We evaluated the impact of milk thistle meal on cholesterol levels and overall health in laying hens. In an engaging trial with 200 hens, we explored four different levels of milk thistle (0%, 15%, 30%, and 60%) combined with varying energy levels over 80 days.
Our findings revealed that incorporating milk thistle significantly lowered serum cholesterol and triglycerides while boosting beneficial high-density lipoprotein (HDL) levels. The hens also showed improved feed conversion efficiency and reduced harmful bacterial counts, highlighting the potential health benefits of milk thistle in poultry diets.
Our findings revealed that incorporating milk thistle significantly lowered serum cholesterol and triglycerides while boosting beneficial high-density lipoprotein (HDL) levels. The hens also showed improved feed conversion efficiency and reduced harmful bacterial counts, highlighting the potential health benefits of milk thistle in poultry diets.
Read More
9
Combination treatment reduces cholesterol
We explored the effects of a nutraceutical blend containing silybum marianum, along with Berberis aristata and monacolin K, on cholesterol levels in patients with low cardiovascular risk.
In our study, 143 participants were involved in a randomized, double-blind, placebo-controlled trial over three months. The results revealed a significant decrease in total cholesterol, triglycerides, and LDL cholesterol with the combination treatment.
While there were positive changes, the study suggests that this blend of ingredients is not only effective for reducing cholesterol but also safe.
In our study, 143 participants were involved in a randomized, double-blind, placebo-controlled trial over three months. The results revealed a significant decrease in total cholesterol, triglycerides, and LDL cholesterol with the combination treatment.
While there were positive changes, the study suggests that this blend of ingredients is not only effective for reducing cholesterol but also safe.
Read More
9
We evaluated the effectiveness of a combination of Berberis aristata and Silybum marianum (called Berberol®) in lowering cholesterol levels among dyslipidemic patients, involving 102 participants. After a six-month preparation with diet and exercise, participants were divided into groups receiving either the supplement or a placebo for three months.
Our findings showed that the natural extract improved total cholesterol and triglyceride levels while boosting the good HDL cholesterol. When treatment paused, cholesterol worsened, but improved again with resumption. Overall, this treatment was safe and effective for managing cholesterol levels and enhancing insulin secretion.
Our findings showed that the natural extract improved total cholesterol and triglyceride levels while boosting the good HDL cholesterol. When treatment paused, cholesterol worsened, but improved again with resumption. Overall, this treatment was safe and effective for managing cholesterol levels and enhancing insulin secretion.
Read More
User Reviews
USERS' SCORE
Good
Based on 18 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Decreased liver enzymes
7 people found this helpful
I bought this for my mother undergoing chemotherapy due to high ASAT and ALAT levels. After using milk thistle alongside Chlorella, her liver support improved significantly, and her ASAT and ALAT levels dropped close to normal.
Read More
10
Liver function support
4 people found this helpful
I have been using Silymarin Milk Thistle Extract for years, and it's brilliant! My liver is in excellent condition, as confirmed by recent blood tests. I've tried both 150 mg and 300 mg doses, both of which protect my liver effectively. Highly recommended!
Read More
9
Bilirubin reduction
3 people found this helpful
I took this supplement for post-cycle therapy after hormonal treatments due to elevated bilirubin levels. I previously tried Heptral, which is more costly. After two months of this product, my tests returned to normal, so I can recommend it.
Read More
9
Pain relief achieved
3 people found this helpful
This supplement is excellent for liver health and bile flow. The milk thistle is well-known for gastrointestinal support. After using it, my right side pain, bitterness in my mouth, and nausea have all vanished. My overall condition has improved significantly; my skin also looks better. I highly recommend it.
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9
Toxin removal
2 people found this helpful
An excellent dietary supplement featuring milk thistle and turmeric. It effectively supports liver health and aids in detoxifying the liver, with guaranteed quality.
Read More
Frequently Asked Questions
7.5
Improved health condition
1 people found this helpful
Very good! I recommend it! The milk thistle plus turmeric products in Taiwan are expensive, but this one is both healthy and affordable. After about a week, my health has improved. My migraines due to high cholesterol have already shown improvement. I just need to continue taking it and manage my diet, rather than purchasing costly products with low content. This is sufficient.
7.5
Detox treatment
2 people found this helpful
My liver function has deteriorated recently, with high cholesterol and poor bile secretion. I decided to detox, and my doctor recommended milk thistle for three months. It has alleviated nausea, and I’m very pleased with the fast delivery of this supplement, which is sufficient for my needs. I plan to reorder.
2
No effect experienced
I used this supplement aiming to lower my high cholesterol, but unfortunately, it did not work for me.
7.5
Decreased liver enzymes
7 people found this helpful
I bought this for my mother undergoing chemotherapy due to high ASAT and ALAT levels. After using milk thistle alongside Chlorella, her liver support improved significantly, and her ASAT and ALAT levels dropped close to normal.
9
Bilirubin reduction
3 people found this helpful
I took this supplement for post-cycle therapy after hormonal treatments due to elevated bilirubin levels. I previously tried Heptral, which is more costly. After two months of this product, my tests returned to normal, so I can recommend it.
9
Liver health restoration
5 people found this helpful
Excellent natural herbal preparation. It helped after three weeks of use. My ALT and AST levels were consistently three times higher than normal, but now they've normalised ideally at 18 each. I continue to take it to normalise liver indicators and have noticed an overall improvement in my health. I even ordered two more jars at a discount.
9
Gallbladder relief
2 people found this helpful
I have gallbladder issues, including dyskinesia and small cholesterol stones, and have taken milk thistle continuously for six months. My gallbladder discomfort has ceased, and there's no heaviness after meals. I take one capsule after breakfast and am very happy with the results.
2
No benefits observed
Unfortunately, I didn’t notice any benefits. While the brand boasts quality, I wish I had opted for a higher dosage with fewer ingredients, purely just milk thistle, as this did not address my concerns related to high cholesterol.
9
Toxin removal
2 people found this helpful
An excellent dietary supplement featuring milk thistle and turmeric. It effectively supports liver health and aids in detoxifying the liver, with guaranteed quality.
10
Liver function support
4 people found this helpful
I have been using Silymarin Milk Thistle Extract for years, and it's brilliant! My liver is in excellent condition, as confirmed by recent blood tests. I've tried both 150 mg and 300 mg doses, both of which protect my liver effectively. Highly recommended!
8
Liver detox effectiveness
4 people found this helpful
An excellent product. Delivery was prompt and the capsules are of a reasonable size. The quality is superb. I take two capsules each morning for liver detox with milk thistle extract. This supplement aids bile cleansing, and I've noticed changes in absorption within just a week. I’ll definitely order a second pack.
7
We examined how a combination of Berberis aristata and Silybum marianum, referred to as Berberol, impacts cholesterol levels in patients with dyslipidaemia. Through a meta-analysis of four randomised controlled trials, we found that Berberol significantly reduced low-density lipoprotein and total cholesterol levels.
However, it did not show a significant impact on high-density lipoprotein, triglycerides, or body mass index. While Berberol appears safe, indicating no adverse liver enzyme changes, the evidence base is limited, requiring more extensive studies to clarify its long-term effectiveness and optimal usage.
However, it did not show a significant impact on high-density lipoprotein, triglycerides, or body mass index. While Berberol appears safe, indicating no adverse liver enzyme changes, the evidence base is limited, requiring more extensive studies to clarify its long-term effectiveness and optimal usage.
9
Silymarin positively influences cholesterol
We conducted a triple-blinded randomized clinical trial with 40 type 2 diabetes patients to see how silymarin impacts cholesterol and blood sugar levels. Over 45 days, participants received either silymarin or a placebo.
Our findings showed that those taking silymarin experienced significant improvements. They had lower fasting blood sugar, reduced triglycerides, and improved levels of good HDL cholesterol.
However, while the results are promising, further research is necessary to confirm these benefits for managing cholesterol in diabetes patients.
Our findings showed that those taking silymarin experienced significant improvements. They had lower fasting blood sugar, reduced triglycerides, and improved levels of good HDL cholesterol.
However, while the results are promising, further research is necessary to confirm these benefits for managing cholesterol in diabetes patients.
8
We examined the effects of silymarin, derived from the milk thistle plant, on liver health in a mouse model with non-alcoholic fatty liver disease (NAFLD).
The study showed that silymarin effectively reduced fat accumulation in the liver while preserving beneficial high-density lipoprotein (HDL) cholesterol levels.
It also decreased harmful low-density lipoprotein (LDL) cholesterol, positively impacting the circulatory system. However, we found no changes in body weight or food intake with silymarin treatment, suggesting a targeted benefit for liver health without broader metabolic effects.
The study showed that silymarin effectively reduced fat accumulation in the liver while preserving beneficial high-density lipoprotein (HDL) cholesterol levels.
It also decreased harmful low-density lipoprotein (LDL) cholesterol, positively impacting the circulatory system. However, we found no changes in body weight or food intake with silymarin treatment, suggesting a targeted benefit for liver health without broader metabolic effects.
References
- Zare Mehrjerdi P, Asadi S, Ehsani E, Askari VR, Baradaran Rahimi V. Silibinin as a major component of milk thistle seed provides promising influences against diabetes and its complications: a systematic review. Naunyn Schmiedebergs Arch Pharmacol. 2024;397:7531. 10.1007/s00210-024-03172-x
- Akhtar MT, Almas T, Safdar S, Saadia M, Qadir R, et al. Antioxidant, Hypoglycemic, Antilipidemic, and Protective Effect of Polyherbal Emulsion (F6-SMONSECCE) on Alloxan-Induced Diabetic Rats. ACS Omega. 2023;8:21642. 10.1021/acsomega.3c01027
- Zhu Y, Zhang X, Du P, Wang Z, Luo P, et al. Dietary herbaceous mixture supplementation reduced hepatic lipid deposition and improved hepatic health status in post-peak laying hens. Poult Sci. 2022;101:101870. 10.1016/j.psj.2022.101870
- Çeribaşı S, Türk G, Özçelik M, Doğan G, Çeribaşı AO, et al. Negative effect of feeding with high energy diets on testes and metabolic blood parameters of male Japanese quails, and positive role of milk thistle seed. Theriogenology. 2020;144:74. 10.1016/j.theriogenology.2019.12.021
- Tóth B, Németh D, Soós A, Hegyi P, Pham-Dobor G, et al. The Effects of a Fixed Combination of Berberis aristata and Silybum marianum on Dyslipidaemia - A Meta-analysis and Systematic Review. Planta Med. 2020;86:132. 10.1055/a-1063-1649
- Ebrahimpour-Koujan S, Gargari BP, Mobasseri M, Valizadeh H, Asghari-Jafarabadi M. Lower glycemic indices and lipid profile among type 2 diabetes mellitus patients who received novel dose of Silybum marianum (L.) Gaertn. (silymarin) extract supplement: A Triple-blinded randomized controlled clinical trial. Phytomedicine. 2018;44:39. 10.1016/j.phymed.2018.03.050
- Hashemi Jabali NS, Mahdavi AH, Ansari Mahyari S, Sedghi M, Akbari Moghaddam Kakhki R. Effects of milk thistle meal on performance, ileal bacterial enumeration, jejunal morphology and blood lipid peroxidation in laying hens fed diets with different levels of metabolizable energy. J Anim Physiol Anim Nutr (Berl). 2018;102:410. 10.1111/jpn.12747
- Derosa G, D'Angelo A, Romano D, Maffioli P. Effects of a Combination of Berberis aristata, Silybum marianum and Monacolin on Lipid Profile in Subjects at Low Cardiovascular Risk; A Double-Blind, Randomized, Placebo-Controlled Trial. Int J Mol Sci. 2017;18. 10.3390/ijms18020343
- Ni X, Wang H. Silymarin attenuated hepatic steatosis through regulation of lipid metabolism and oxidative stress in a mouse model of nonalcoholic fatty liver disease (NAFLD). Am J Transl Res. 2016;8:1073.
- Morovat M, Chamani M, Zarei A, Sadeghi AA. Dietary but not in ovo feeding of Silybum marianum extract resulted in an improvement in performance, immunity and carcass characteristics and decreased the adverse effects of high temperatures in broilers. Br Poult Sci. 2016;57:105. 10.1080/00071668.2015.1121537
- Di Pierro F, Bellone I, Rapacioli G, Putignano P. Clinical role of a fixed combination of standardized Berberis aristata and Silybum marianum extracts in diabetic and hypercholesterolemic patients intolerant to statins. Diabetes Metab Syndr Obes. 2015;8:89. 10.2147/DMSO.S78877
- Derosa G, Romano D, D'Angelo A, Maffioli P. Berberis aristata combined with Silybum marianum on lipid profile in patients not tolerating statins at high doses. Atherosclerosis. 2015;239:87. 10.1016/j.atherosclerosis.2014.12.043
- Derosa G, Bonaventura A, Bianchi L, Romano D, D'Angelo A, et al. Berberis aristata/Silybum marianum fixed combination on lipid profile and insulin secretion in dyslipidemic patients. Expert Opin Biol Ther. 2013;13:1495. 10.1517/14712598.2013.832751
- Cacciapuoti F, Scognamiglio A, Palumbo R, Forte R, Cacciapuoti F. Silymarin in non alcoholic fatty liver disease. World J Hepatol. 2013;5:109. 10.4254/wjh.v5.i3.109
- Skottová N, Kazdová L, Oliyarnyk O, Vecera R, Sobolová L, et al. Phenolics-rich extracts from Silybum marianum and Prunella vulgaris reduce a high-sucrose diet induced oxidative stress in hereditary hypertriglyceridemic rats. Pharmacol Res. 2004;50:123.
- Skottová N, Krecman V, Walterová D, Ulrichová J, Kosina P, et al. Effect of silymarin on serum cholesterol levels in rats. Acta Univ Palacki Olomuc Fac Med. 1998;141:87.
