Last update
4/18/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
USERS' SCORE
Good
Based on 3 Reviews
8.6
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Calories
5
Total Carbohydrate
1 g
<1%**
Milk Thistle Extract (Silybum marianum)(Fruit/Seeds) (Standardized to 240 mg Silymarin Flavonoids - equivalent 80%)
300 mg
†
Turmeric (Curcuma longa) (Root)
700 mg
†
Top Medical Research Studies
9
We investigated the use of silybin nanoparticles in treating ulcerative colitis (UC). These nanoparticles were carefully prepared and tested in a rat model, where UC was induced with acetic acid.
Over five days, we compared the effects of silybin nanoparticles with other treatments. The results showed significant improvements in both macroscopic and histopathological evaluations.
Notably, levels of harmful markers such as TNF-α and IL-6 were reduced, highlighting the potential benefit of silybin nanoparticles in ulcer treatment.
Over five days, we compared the effects of silybin nanoparticles with other treatments. The results showed significant improvements in both macroscopic and histopathological evaluations.
Notably, levels of harmful markers such as TNF-α and IL-6 were reduced, highlighting the potential benefit of silybin nanoparticles in ulcer treatment.
Read More
8
We explored the protective effects of an aqueous leaf extract from a tropical tree against stomach damage caused by diclofenac, a common pain reliever known to harm the gastric lining with excessive use. In our study with 30 rats, we compared groups that received different treatments—including the leaf extract and a well-known standard, silymarin.
Ultimately, we observed that the leaf extract showed significant gastroprotective activity, improving antioxidant levels and reducing harmful symptoms typically seen with diclofenac treatment. This suggests that the leaf extract could be beneficial in managing gastric toxicity.
Ultimately, we observed that the leaf extract showed significant gastroprotective activity, improving antioxidant levels and reducing harmful symptoms typically seen with diclofenac treatment. This suggests that the leaf extract could be beneficial in managing gastric toxicity.
Read More
8
Effective gastro-protective treatment observed
We explored the effects of silymarin (SM) on gastric ulcers induced by NSAIDs in rats. By using a controlled study design, we found that pretreatment with SM significantly reduced gastric mucosal damage and inflammation.
It decreased ulcer severity and improved tissue structure. Additionally, SM effectively lowered inflammation markers and oxidative stress levels, enhancing the stomach's protective mechanisms.
Our findings suggest that silymarin offers important gastro-protective benefits, making it a promising option for those facing gastric ulcers.
It decreased ulcer severity and improved tissue structure. Additionally, SM effectively lowered inflammation markers and oxidative stress levels, enhancing the stomach's protective mechanisms.
Our findings suggest that silymarin offers important gastro-protective benefits, making it a promising option for those facing gastric ulcers.
Read More
Most Useful Reviews
10
Cured ulcer quickly
This product worked remarkably well as my mouth ulcer was cured almost instantly.
Read More
9
Strengthens resistance
This product possesses an antiulcer effect and promotes the healing of ulcers. It defends the body against harmful chemical and physical influences that can lead to tumour formation, offering significant antioxidant and antimutagenic benefits. It boosts the body's resilience and fortifies the immune system.
Read More
7.5
Relieves inflammation
Milk thistle seeds are effective in reducing inflammation when used externally, making them valuable in the comprehensive treatment of ulcers, wounds, bedsores, and inflammatory skin conditions.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
- All Researches
9
We investigated the use of silybin nanoparticles in treating ulcerative colitis (UC). These nanoparticles were carefully prepared and tested in a rat model, where UC was induced with acetic acid.
Over five days, we compared the effects of silybin nanoparticles with other treatments. The results showed significant improvements in both macroscopic and histopathological evaluations.
Notably, levels of harmful markers such as TNF-α and IL-6 were reduced, highlighting the potential benefit of silybin nanoparticles in ulcer treatment.
Over five days, we compared the effects of silybin nanoparticles with other treatments. The results showed significant improvements in both macroscopic and histopathological evaluations.
Notably, levels of harmful markers such as TNF-α and IL-6 were reduced, highlighting the potential benefit of silybin nanoparticles in ulcer treatment.
Read More
8
We explored the protective effects of an aqueous leaf extract from a tropical tree against stomach damage caused by diclofenac, a common pain reliever known to harm the gastric lining with excessive use. In our study with 30 rats, we compared groups that received different treatments—including the leaf extract and a well-known standard, silymarin.
Ultimately, we observed that the leaf extract showed significant gastroprotective activity, improving antioxidant levels and reducing harmful symptoms typically seen with diclofenac treatment. This suggests that the leaf extract could be beneficial in managing gastric toxicity.
Ultimately, we observed that the leaf extract showed significant gastroprotective activity, improving antioxidant levels and reducing harmful symptoms typically seen with diclofenac treatment. This suggests that the leaf extract could be beneficial in managing gastric toxicity.
Read More
8
Effective gastro-protective treatment observed
We explored the effects of silymarin (SM) on gastric ulcers induced by NSAIDs in rats. By using a controlled study design, we found that pretreatment with SM significantly reduced gastric mucosal damage and inflammation.
It decreased ulcer severity and improved tissue structure. Additionally, SM effectively lowered inflammation markers and oxidative stress levels, enhancing the stomach's protective mechanisms.
Our findings suggest that silymarin offers important gastro-protective benefits, making it a promising option for those facing gastric ulcers.
It decreased ulcer severity and improved tissue structure. Additionally, SM effectively lowered inflammation markers and oxidative stress levels, enhancing the stomach's protective mechanisms.
Our findings suggest that silymarin offers important gastro-protective benefits, making it a promising option for those facing gastric ulcers.
Read More
8
Natursil effective for ulcer treatment
We examined the effectiveness of Natursil, a biologically active component, in treating stomach and duodenal ulcers. Our findings demonstrated that Natursil works better than traditional treatments, particularly in enhancing healing time and adhesion.
Additionally, we observed that Natursil showed a stronger antiulcer effect compared to hippophae oil. We found no advantages to using transendoscopic spraying over oral administration of the drug for ulcer treatment. The unique structure of Natursil may play a crucial role in its effectiveness through its impact on metabolic processes.
Additionally, we observed that Natursil showed a stronger antiulcer effect compared to hippophae oil. We found no advantages to using transendoscopic spraying over oral administration of the drug for ulcer treatment. The unique structure of Natursil may play a crucial role in its effectiveness through its impact on metabolic processes.
Read More
8
We investigated the effects of silymarin, a compound from the Silybum marianum plant, on ulcers caused by blood flow issues in rats. By comparing silymarin to the treatment allopurinol, we observed that silymarin significantly reduced ulcer severity.
Specifically, higher doses of silymarin led to lower ulcer indexes, although allopurinol proved more effective. The research highlighted that silymarin's gastroprotective properties might come from its ability to inhibit neutrophil activity, which plays a role in gastric injury.
Specifically, higher doses of silymarin led to lower ulcer indexes, although allopurinol proved more effective. The research highlighted that silymarin's gastroprotective properties might come from its ability to inhibit neutrophil activity, which plays a role in gastric injury.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
10
Cured ulcer quickly
This product worked remarkably well as my mouth ulcer was cured almost instantly.
Read More
9
Strengthens resistance
This product possesses an antiulcer effect and promotes the healing of ulcers. It defends the body against harmful chemical and physical influences that can lead to tumour formation, offering significant antioxidant and antimutagenic benefits. It boosts the body's resilience and fortifies the immune system.
Read More
7.5
Relieves inflammation
Milk thistle seeds are effective in reducing inflammation when used externally, making them valuable in the comprehensive treatment of ulcers, wounds, bedsores, and inflammatory skin conditions.
Read More
Frequently Asked Questions
10
Cured ulcer quickly
This product worked remarkably well as my mouth ulcer was cured almost instantly.
9
Strengthens resistance
This product possesses an antiulcer effect and promotes the healing of ulcers. It defends the body against harmful chemical and physical influences that can lead to tumour formation, offering significant antioxidant and antimutagenic benefits. It boosts the body's resilience and fortifies the immune system.
7.5
Relieves inflammation
Milk thistle seeds are effective in reducing inflammation when used externally, making them valuable in the comprehensive treatment of ulcers, wounds, bedsores, and inflammatory skin conditions.
8
Effective gastro-protective treatment observed
We explored the effects of silymarin (SM) on gastric ulcers induced by NSAIDs in rats. By using a controlled study design, we found that pretreatment with SM significantly reduced gastric mucosal damage and inflammation.
It decreased ulcer severity and improved tissue structure. Additionally, SM effectively lowered inflammation markers and oxidative stress levels, enhancing the stomach's protective mechanisms.
Our findings suggest that silymarin offers important gastro-protective benefits, making it a promising option for those facing gastric ulcers.
It decreased ulcer severity and improved tissue structure. Additionally, SM effectively lowered inflammation markers and oxidative stress levels, enhancing the stomach's protective mechanisms.
Our findings suggest that silymarin offers important gastro-protective benefits, making it a promising option for those facing gastric ulcers.
8
We investigated the effects of silymarin, a compound from the Silybum marianum plant, on ulcers caused by blood flow issues in rats. By comparing silymarin to the treatment allopurinol, we observed that silymarin significantly reduced ulcer severity.
Specifically, higher doses of silymarin led to lower ulcer indexes, although allopurinol proved more effective. The research highlighted that silymarin's gastroprotective properties might come from its ability to inhibit neutrophil activity, which plays a role in gastric injury.
Specifically, higher doses of silymarin led to lower ulcer indexes, although allopurinol proved more effective. The research highlighted that silymarin's gastroprotective properties might come from its ability to inhibit neutrophil activity, which plays a role in gastric injury.
9
We investigated the use of silybin nanoparticles in treating ulcerative colitis (UC). These nanoparticles were carefully prepared and tested in a rat model, where UC was induced with acetic acid.
Over five days, we compared the effects of silybin nanoparticles with other treatments. The results showed significant improvements in both macroscopic and histopathological evaluations.
Notably, levels of harmful markers such as TNF-α and IL-6 were reduced, highlighting the potential benefit of silybin nanoparticles in ulcer treatment.
Over five days, we compared the effects of silybin nanoparticles with other treatments. The results showed significant improvements in both macroscopic and histopathological evaluations.
Notably, levels of harmful markers such as TNF-α and IL-6 were reduced, highlighting the potential benefit of silybin nanoparticles in ulcer treatment.
8
Natursil effective for ulcer treatment
We examined the effectiveness of Natursil, a biologically active component, in treating stomach and duodenal ulcers. Our findings demonstrated that Natursil works better than traditional treatments, particularly in enhancing healing time and adhesion.
Additionally, we observed that Natursil showed a stronger antiulcer effect compared to hippophae oil. We found no advantages to using transendoscopic spraying over oral administration of the drug for ulcer treatment. The unique structure of Natursil may play a crucial role in its effectiveness through its impact on metabolic processes.
Additionally, we observed that Natursil showed a stronger antiulcer effect compared to hippophae oil. We found no advantages to using transendoscopic spraying over oral administration of the drug for ulcer treatment. The unique structure of Natursil may play a crucial role in its effectiveness through its impact on metabolic processes.
8
We explored the protective effects of an aqueous leaf extract from a tropical tree against stomach damage caused by diclofenac, a common pain reliever known to harm the gastric lining with excessive use. In our study with 30 rats, we compared groups that received different treatments—including the leaf extract and a well-known standard, silymarin.
Ultimately, we observed that the leaf extract showed significant gastroprotective activity, improving antioxidant levels and reducing harmful symptoms typically seen with diclofenac treatment. This suggests that the leaf extract could be beneficial in managing gastric toxicity.
Ultimately, we observed that the leaf extract showed significant gastroprotective activity, improving antioxidant levels and reducing harmful symptoms typically seen with diclofenac treatment. This suggests that the leaf extract could be beneficial in managing gastric toxicity.
References
- Simon JP, Evan Prince S. Ameliorative activity of aqueous leaf extract from against diclofenac-administered toxicity on rat stomach and intestine. J Histotechnol. 2021;44:114. 10.1080/01478885.2020.1861917
- Arafa Keshk W, Zahran SM, Katary MA, Abd-Elaziz Ali D. Modulatory effect of silymarin on nuclear factor-erythroid-2-related factor 2 regulated redox status, nuclear factor-κB mediated inflammation and apoptosis in experimental gastric ulcer. Chem Biol Interact. 2017;273:266. 10.1016/j.cbi.2017.06.022
- Varshosaz J, Minaiyan M, Khaleghi N. Eudragit nanoparticles loaded with silybin: a detailed study of preparation, freeze-drying condition and in vitro/in vivo evaluation. J Microencapsul. 2015;32:211. 10.3109/02652048.2014.995728
- Gil'miiarova FN, Tutel'ian VA, Radomskaia VM, Gapparov MM, Kuznetsova OIu, et al. [Effect of biologically active components of natursil on the course of reparative processes in the gastrointestinal mucosa in experiments and in patients with stomach and duodenal ulcers]. Vopr Pitan. 2001;70:29. PubMed
- Alarcón de la Lastra AC, Martín MJ, Motilva V, Jiménez M, La Casa C, et al. Gastroprotection induced by silymarin, the hepatoprotective principle of Silybum marianum in ischemia-reperfusion mucosal injury: role of neutrophils. Planta Med. 1995;61:116. PubMed
