Last update
4/30/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.4
USERS' SCORE
Good
Based on 9 Reviews
8.5
Supplement Facts
Serving Size: 1/2 Level Teaspoon (approx. 1.9 g)
Amount Per Serving
%DV
Vitamin C (from Sodium Ascorbate)
1.67 g (1,670 mg
1856%
Sodium (from Sodium Ascorbate)
210 mg
9%
Top Medical Research Studies
9
We explored the potential of a new ascorbic acid derivative, 6-Deoxy-2-methyl-6-(-hexadecanoyl)amino-l-ascorbic acid, as a treatment for allergies. This study involved synthesizing various palmitoyl derivatives and assessing their ability to inhibit allergic responses in a lab setting. The findings indicated that 2-Me-6-Palm-AA showed significantly more promise in reducing allergic reactions compared to earlier derivatives. However, while these results are exciting, further research is needed to fully understand its effectiveness and potential as a therapeutic solution.
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9
We investigated whether applying the antioxidant vitamin C to the skin could lessen allergic reactions to p-phenylenediamine (PPD), a common ingredient in hair dyes. In a study involving 28 volunteers with known PPD allergies, we treated skin with a vitamin C formulation for 10 minutes before exposing it to PPD.
The results were promising, showing that about 75% of the participants experienced reduced allergic reactions compared to untreated skin. This suggests that adding vitamin C to the skin before hair dyeing could effectively help manage allergic contact dermatitis.
The results were promising, showing that about 75% of the participants experienced reduced allergic reactions compared to untreated skin. This suggests that adding vitamin C to the skin before hair dyeing could effectively help manage allergic contact dermatitis.
Read More
8
We investigated the effects of sodium ascorbate, a derivative of vitamin C, on allergies. Our findings from a study using various synthesized forms of this compound indicated that certain derivatives effectively reduced allergy-related reactions in mice. The results demonstrated a clear inhibition of harmful enzymes and degranulation, particularly with one potent derivative. This suggests sodium ascorbate could become a valuable option for allergy treatment, showcasing its potential benefits in managing allergic responses.
Read More
Most Useful Reviews
9
Helps prevent illnesses
115 people found this helpful
Good vitamin C! The jar lasts a long time and does not irritate my stomach. It is well absorbed and does not cause allergies. We take a loading dose at the first signs of ARVI, which helps the whole family avoid getting ill.
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7.5
Gentle on stomach
2 people found this helpful
Excellent vitamin C for the entire family. It lasts for ages, has no taste, and does not irritate the stomach. I haven't experienced any allergies. Highly recommend.
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10
Better absorption
Sodium ascorbate is a buffered form of vitamin C that’s better absorbed and does not irritate my stomach. It does not cause allergies and preserves tooth enamel, even with high doses.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.4
- All Researches
9
Whey proteins and allergenicity reduction
We investigated how adding ascorbic acid affects whey protein's allergenicity in the context of cow's milk allergy. Our study tested various treatments, including iron-complexed protein hydrolysates. We found that the allergenic potential was significantly lowered—up to 60%—when ascorbic acid was involved. The results demonstrate a promising approach to creating hypoallergenic supplements, making it kinder for those with milk sensitivities.
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9
We explored the potential of a new ascorbic acid derivative, 6-Deoxy-2-methyl-6-(-hexadecanoyl)amino-l-ascorbic acid, as a treatment for allergies. This study involved synthesizing various palmitoyl derivatives and assessing their ability to inhibit allergic responses in a lab setting. The findings indicated that 2-Me-6-Palm-AA showed significantly more promise in reducing allergic reactions compared to earlier derivatives. However, while these results are exciting, further research is needed to fully understand its effectiveness and potential as a therapeutic solution.
Read More
9
We observed a case of scurvy in a patient who presented with sudden joint pain and purple spots on the skin due to a vitamin C deficiency. After testing low vitamin C levels, we treated the patient with vitamin C supplements, leading to significant improvement.
This condition, often seen in people with limited access to fruits and vegetables, can sometimes manifest in unusual ways, such as unexplained skin bleeding. Identifying scurvy early can have a major impact on treatment and recovery.
This condition, often seen in people with limited access to fruits and vegetables, can sometimes manifest in unusual ways, such as unexplained skin bleeding. Identifying scurvy early can have a major impact on treatment and recovery.
Read More
9
We investigated whether applying the antioxidant vitamin C to the skin could lessen allergic reactions to p-phenylenediamine (PPD), a common ingredient in hair dyes. In a study involving 28 volunteers with known PPD allergies, we treated skin with a vitamin C formulation for 10 minutes before exposing it to PPD.
The results were promising, showing that about 75% of the participants experienced reduced allergic reactions compared to untreated skin. This suggests that adding vitamin C to the skin before hair dyeing could effectively help manage allergic contact dermatitis.
The results were promising, showing that about 75% of the participants experienced reduced allergic reactions compared to untreated skin. This suggests that adding vitamin C to the skin before hair dyeing could effectively help manage allergic contact dermatitis.
Read More
8
We investigated the effects of sodium ascorbate, a derivative of vitamin C, on allergies. Our findings from a study using various synthesized forms of this compound indicated that certain derivatives effectively reduced allergy-related reactions in mice. The results demonstrated a clear inhibition of harmful enzymes and degranulation, particularly with one potent derivative. This suggests sodium ascorbate could become a valuable option for allergy treatment, showcasing its potential benefits in managing allergic responses.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Helps prevent illnesses
115 people found this helpful
Good vitamin C! The jar lasts a long time and does not irritate my stomach. It is well absorbed and does not cause allergies. We take a loading dose at the first signs of ARVI, which helps the whole family avoid getting ill.
Read More
7.5
Gentle on stomach
2 people found this helpful
Excellent vitamin C for the entire family. It lasts for ages, has no taste, and does not irritate the stomach. I haven't experienced any allergies. Highly recommend.
Read More
10
Better absorption
Sodium ascorbate is a buffered form of vitamin C that’s better absorbed and does not irritate my stomach. It does not cause allergies and preserves tooth enamel, even with high doses.
Read More
9
Economical choice
A good form of vitamin C that lasts a long time and does not cause allergies or irritate the stomach. It’s well absorbed and suitable for children from one year old.
Read More
9
Family-friendly
This vitamin C lasts long, does not irritate our stomachs, and doesn't cause allergies. We take it as a family.
Read More
Frequently Asked Questions
7
We investigated how intravenous vitamin C, particularly sodium ascorbate, could impact allergy symptoms in a group of 71 patients. In this observational study, we noted significant reductions in both allergy-specific and general symptoms, such as fatigue and mental concentration issues, indicating potential benefits from sodium ascorbate treatment. Notably, over half of the patients relied solely on vitamin C without other allergy medications. While our findings are promising, we stress the need for a larger randomized controlled trial to confirm these initial results.
8
We investigated the effects of sodium ascorbate, a derivative of vitamin C, on allergies. Our findings from a study using various synthesized forms of this compound indicated that certain derivatives effectively reduced allergy-related reactions in mice. The results demonstrated a clear inhibition of harmful enzymes and degranulation, particularly with one potent derivative. This suggests sodium ascorbate could become a valuable option for allergy treatment, showcasing its potential benefits in managing allergic responses.
8
We conducted a thorough evaluation of how vitamin C, when combined with pleuran, impacts asthma control and respiratory issues in children suffering from perennial asthma. The study was meticulously designed as a double-blind, placebo-controlled trial involving 230 children aged 7 to 17 years. This means that neither the participants nor the researchers knew who was receiving the active treatment or the placebo, ensuring the findings were reliable.
The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.
While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.
While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
9
We investigated whether applying the antioxidant vitamin C to the skin could lessen allergic reactions to p-phenylenediamine (PPD), a common ingredient in hair dyes. In a study involving 28 volunteers with known PPD allergies, we treated skin with a vitamin C formulation for 10 minutes before exposing it to PPD.
The results were promising, showing that about 75% of the participants experienced reduced allergic reactions compared to untreated skin. This suggests that adding vitamin C to the skin before hair dyeing could effectively help manage allergic contact dermatitis.
The results were promising, showing that about 75% of the participants experienced reduced allergic reactions compared to untreated skin. This suggests that adding vitamin C to the skin before hair dyeing could effectively help manage allergic contact dermatitis.
References
- Lukose SJ, Divya MP, Beena AK, Rajakumar SN, Babu PS. Reduced allergenicity of hydrolysed whey protein concentrate complexed with iron: the effect of different enzymes, degree of hydrolysis and ascorbic acid. J Food Sci Technol. 2025;62:940. 10.1007/s13197-024-06085-y
- Miura K, Matsuno H, Iwaoka Y, Ito H, Tai A. Antiallergic Activity of 6-Deoxy-2--methyl-6-(-hexadecanoyl)amino-l-ascorbic Acid. Molecules. 2021;26. 10.3390/molecules26154684
- Vollbracht C, Raithel M, Krick B, Kraft K, Hagel AF. Intravenous vitamin C in the treatment of allergies: an interim subgroup analysis of a long-term observational study. J Int Med Res. 2018;46:3640. 10.1177/0300060518777044
- Miura K, Morishita Y, Matsuno H, Aota Y, Ito H, et al. Anti-Allergic Activity of Monoacylated Ascorbic Acid 2-Glucosides. Molecules. 2017;22. 10.3390/molecules22122202
- Mintsoulis D, Milman N, Fahim S. A Case of Scurvy-Uncommon Disease-Presenting as Panniculitis, Purpura, and Oligoarthritis. J Cutan Med Surg. 2016;20:592. PubMed
- Basketter DA, White IR, Kullavanijaya P, Tresukosol P, Wichaidit M, et al. Influence of vitamin C on the elicitation of allergic contact dermatitis to p-phenylenediamine. Contact Dermatitis. 2016;74:368. 10.1111/cod.12576
- Jesenak M, Hrubisko M, Chudek J, Bystron J, Rennerova Z, et al. Beneficial effects of pleuran on asthma control and respiratory tract-infection frequency in children with perennial asthma. Sci Rep. 2025;15:7146. 10.1038/s41598-025-91830-2
