Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.4
USERS' SCORE
Good
Based on 13 Reviews
8.2
Supplement Facts
Serving Size: 1/2 Level Teaspoon (approx. 1.9 g)
Amount Per Serving
%DV
Vitamin C (from Sodium Ascorbate)
1.67 g (1,670 mg
1856%
Sodium (from Sodium Ascorbate)
210 mg
9%
Top Medical Research Studies
8
We aimed to discover how vitamin C supplementation affects oxidative stress in individuals diagnosed with chronic gastritis. In this study, we looked at 244 Japanese patients suffering from atrophic gastritis. They were randomly assigned to receive either 50 mg or 500 mg of vitamin C every day for five years.
After analyzing the results, we found notable differences between the two groups. The high-dose group experienced a significant decrease in reactive oxygen species (ROS), suggesting that vitamin C may help reduce oxidative stress associated with chronic gastritis. In contrast, the low-dose group reported an increase in ROS levels. These findings prompt further interest in how vitamin C can protect against oxidative stress in similar conditions.
Overall, our study supports the idea that higher doses of vitamin C could have a beneficial effect on oxidative stress, particularly in those dealing with gastritis. This insight opens avenues for considering vitamin C as a potential supportive treatment for managing oxidative stress-related issues in digestive health.
After analyzing the results, we found notable differences between the two groups. The high-dose group experienced a significant decrease in reactive oxygen species (ROS), suggesting that vitamin C may help reduce oxidative stress associated with chronic gastritis. In contrast, the low-dose group reported an increase in ROS levels. These findings prompt further interest in how vitamin C can protect against oxidative stress in similar conditions.
Overall, our study supports the idea that higher doses of vitamin C could have a beneficial effect on oxidative stress, particularly in those dealing with gastritis. This insight opens avenues for considering vitamin C as a potential supportive treatment for managing oxidative stress-related issues in digestive health.
Read More
9
We sought to understand how vitamin C affects the absorption of levothyroxine, a common medication for hypothyroidism, particularly in patients who also experience gastritis. Our study involved 31 patients, most of whom had poorly controlled hypothyroidism along with gastrointestinal issues.
Participants took levothyroxine alongside a solution that either contained or did not contain vitamin C, and we monitored their hormone levels over several months. Our findings revealed that vitamin C can actually improve levels of free T4 and T3, as well as TSH, suggesting it enhances the absorption of medication in these patients.
This is particularly significant because individuals dealing with both hypothyroidism and gastritis often struggle to maintain stable thyroid hormone levels. Our research indicates that incorporating vitamin C into their treatment regimen could serve as a beneficial strategy in managing their condition.
Participants took levothyroxine alongside a solution that either contained or did not contain vitamin C, and we monitored their hormone levels over several months. Our findings revealed that vitamin C can actually improve levels of free T4 and T3, as well as TSH, suggesting it enhances the absorption of medication in these patients.
This is particularly significant because individuals dealing with both hypothyroidism and gastritis often struggle to maintain stable thyroid hormone levels. Our research indicates that incorporating vitamin C into their treatment regimen could serve as a beneficial strategy in managing their condition.
Read More
8
We examined how sodium ascorbate, a form of Vitamin C, affects chronic atrophic gastritis (CAG). Our study revealed that patients receiving sodium ascorbate showed notable improvements in their blood parameters and overall gastric health.
Furthermore, laboratory studies indicated that sodium ascorbate enhanced cell viability and reduced inflammation markers in treated cells. While we observed promising results, the mechanism through which sodium ascorbate acts includes interactions with key proteins involved in inflammation and cell survival, suggesting its potential as a new therapeutic approach for CAG.
Furthermore, laboratory studies indicated that sodium ascorbate enhanced cell viability and reduced inflammation markers in treated cells. While we observed promising results, the mechanism through which sodium ascorbate acts includes interactions with key proteins involved in inflammation and cell survival, suggesting its potential as a new therapeutic approach for CAG.
Read More
Most Useful Reviews
7.5
No stomach issues
10 people found this helpful
Excellent product! This modern form of vitamin C aids calcium and iron absorption, removes toxins, and protects blood vessel walls from cholesterol plaques. I ordered it due to my stomach's intolerance to the usual vitamin C, as I have chronic gastritis. I’ve taken 1/3 teaspoon for two weeks, and I’ve had no adverse reactions from my stomach. This vitamin is essential at the moment. If you found this helpful, please like it. Thank you!
Read More
9
Avoids heartburn
3 people found this helpful
A real find for gastritis patients! The benefits of this vitamin C are undeniable for me. With my gastritis and acidity issues, I can take this non-acidic form of vitamin C without provoking heartburn. I prefer powder to pills as I can adjust the daily dosage. Stay healthy!
Read More
9
No discomfort experienced
1 people found this helpful
I got it for my wife who has stomach issues (gastritis). This non-acidic vitamin C doesn’t irritate her stomach or cause discomfort. It has a taste reminiscent of water with soda, making it easy to drink. If my review was useful, please give it a thumbs up. Thank you!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.4
- All Researches
9.5
We conducted a one-year double-blind placebo-controlled trial to explore the effects of daily supplementation on patients with gastric premalignant lesions known as intestinal metaplasia (IM). Our focus was on a specific supplement consisting of Ester-C, which includes 2100 mg of Ca-ascorbate and 340 mg of bioflavonoids, alongside other antioxidants.
The results were promising, showing a significant decrease in the activity of ornithine decarboxylase, an enzyme that can indicate abnormal cell growth. Remarkably, we observed that 11 out of 18 patients showed nearly total regression of their IM, which translates to a success rate of 61%.
While this study highlights the potential benefits of antioxidant supplementation, including vitamin C, it's essential to note that multiple components were present in the treatment. This complexity makes it challenging to pinpoint the specific effect of vitamin C alone on gastritis treatment.
The results were promising, showing a significant decrease in the activity of ornithine decarboxylase, an enzyme that can indicate abnormal cell growth. Remarkably, we observed that 11 out of 18 patients showed nearly total regression of their IM, which translates to a success rate of 61%.
While this study highlights the potential benefits of antioxidant supplementation, including vitamin C, it's essential to note that multiple components were present in the treatment. This complexity makes it challenging to pinpoint the specific effect of vitamin C alone on gastritis treatment.
Read More
9
We examined how sodium ascorbate impacts gastritis by analyzing its effects on rats treated with a harmful substance that causes stomach lesions. After administering sodium ascorbate following the treatment, we observed a significant reduction in the progression of gastric mucosal lesions. Our findings indicate that sodium ascorbate helps maintain healthy mucosal conditions and supports recovery after gastric injury. However, it's important to note that the observed effects were specific to the experimental conditions set in our study, and more research is needed to fully understand the implications for human health.
Read More
9
We sought to understand how vitamin C affects the absorption of levothyroxine, a common medication for hypothyroidism, particularly in patients who also experience gastritis. Our study involved 31 patients, most of whom had poorly controlled hypothyroidism along with gastrointestinal issues.
Participants took levothyroxine alongside a solution that either contained or did not contain vitamin C, and we monitored their hormone levels over several months. Our findings revealed that vitamin C can actually improve levels of free T4 and T3, as well as TSH, suggesting it enhances the absorption of medication in these patients.
This is particularly significant because individuals dealing with both hypothyroidism and gastritis often struggle to maintain stable thyroid hormone levels. Our research indicates that incorporating vitamin C into their treatment regimen could serve as a beneficial strategy in managing their condition.
Participants took levothyroxine alongside a solution that either contained or did not contain vitamin C, and we monitored their hormone levels over several months. Our findings revealed that vitamin C can actually improve levels of free T4 and T3, as well as TSH, suggesting it enhances the absorption of medication in these patients.
This is particularly significant because individuals dealing with both hypothyroidism and gastritis often struggle to maintain stable thyroid hormone levels. Our research indicates that incorporating vitamin C into their treatment regimen could serve as a beneficial strategy in managing their condition.
Read More
8
We examined how sodium ascorbate, a form of Vitamin C, affects chronic atrophic gastritis (CAG). Our study revealed that patients receiving sodium ascorbate showed notable improvements in their blood parameters and overall gastric health.
Furthermore, laboratory studies indicated that sodium ascorbate enhanced cell viability and reduced inflammation markers in treated cells. While we observed promising results, the mechanism through which sodium ascorbate acts includes interactions with key proteins involved in inflammation and cell survival, suggesting its potential as a new therapeutic approach for CAG.
Furthermore, laboratory studies indicated that sodium ascorbate enhanced cell viability and reduced inflammation markers in treated cells. While we observed promising results, the mechanism through which sodium ascorbate acts includes interactions with key proteins involved in inflammation and cell survival, suggesting its potential as a new therapeutic approach for CAG.
Read More
8
We explored whether sodium ascorbate, along with alpha tocopherol, could impact gastritis caused by Helicobacter pylori in patients. Those with H. pylori-positive nonulcer dyspepsia received vitamin C and E supplements over four weeks.
After treatment, we observed a significant reduction in H. pylori intensity and neutrophilic activity, suggesting that boosting vitamin C and E levels may enhance antibiotic effectiveness. Interestingly, while the antioxidant capacity remained unchanged, vitamin concentrations in the gastric tissue increased, indicating a potential role for these vitamins in managing gastritis.
After treatment, we observed a significant reduction in H. pylori intensity and neutrophilic activity, suggesting that boosting vitamin C and E levels may enhance antibiotic effectiveness. Interestingly, while the antioxidant capacity remained unchanged, vitamin concentrations in the gastric tissue increased, indicating a potential role for these vitamins in managing gastritis.
Read More
User Reviews
USERS' SCORE
Good
Based on 13 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
No stomach issues
10 people found this helpful
Excellent product! This modern form of vitamin C aids calcium and iron absorption, removes toxins, and protects blood vessel walls from cholesterol plaques. I ordered it due to my stomach's intolerance to the usual vitamin C, as I have chronic gastritis. I’ve taken 1/3 teaspoon for two weeks, and I’ve had no adverse reactions from my stomach. This vitamin is essential at the moment. If you found this helpful, please like it. Thank you!
Read More
9
Avoids heartburn
3 people found this helpful
A real find for gastritis patients! The benefits of this vitamin C are undeniable for me. With my gastritis and acidity issues, I can take this non-acidic form of vitamin C without provoking heartburn. I prefer powder to pills as I can adjust the daily dosage. Stay healthy!
Read More
9
No discomfort experienced
1 people found this helpful
I got it for my wife who has stomach issues (gastritis). This non-acidic vitamin C doesn’t irritate her stomach or cause discomfort. It has a taste reminiscent of water with soda, making it easy to drink. If my review was useful, please give it a thumbs up. Thank you!
Read More
7.5
Convenient powder form
1 people found this helpful
Can be added to food! This powder form of vitamin C is very user-friendly and works well for absorption, especially with my gastritis! I often take this particular version, and it’s very economical in terms of price and duration. The powder's form allows easy dosage adjustment. I wish to share my experiences without giving medical advice, as reviews should serve as personal insights.
Read More
9
Essential for gastritis
Sodium ascorbate is essential for gastritis. That’s why I bought it.
Read More
Frequently Asked Questions
7.5
No stomach issues
10 people found this helpful
Excellent product! This modern form of vitamin C aids calcium and iron absorption, removes toxins, and protects blood vessel walls from cholesterol plaques. I ordered it due to my stomach's intolerance to the usual vitamin C, as I have chronic gastritis. I’ve taken 1/3 teaspoon for two weeks, and I’ve had no adverse reactions from my stomach. This vitamin is essential at the moment. If you found this helpful, please like it. Thank you!
9
Avoids heartburn
3 people found this helpful
A real find for gastritis patients! The benefits of this vitamin C are undeniable for me. With my gastritis and acidity issues, I can take this non-acidic form of vitamin C without provoking heartburn. I prefer powder to pills as I can adjust the daily dosage. Stay healthy!
9
Family-friendly
This excellent vitamin C in sodium ascorbate form does not irritate the gastric mucosa, vital for individuals with gastritis. It can be taken in large doses, and it's suitable for my young daughter.
9
Stomach-friendly
For those whose stomach struggles with ascorbic acid, this is a brilliant alternative. It’s a lifesaver for anyone suffering from gastritis.
7.5
Convenient powder form
1 people found this helpful
Can be added to food! This powder form of vitamin C is very user-friendly and works well for absorption, especially with my gastritis! I often take this particular version, and it’s very economical in terms of price and duration. The powder's form allows easy dosage adjustment. I wish to share my experiences without giving medical advice, as reviews should serve as personal insights.
4
Supports health
Gorgeous vitamin C! I have gastritis, and it didn’t upset my stomach at all. It helped me stay well, and I took it with iron, plus other supplements and bioflavonoids.
7.5
Great for gastritis
An excellent choice of vitamin C for people like me who have gastritis. I take it alongside collagen for added beauty benefits.
8
We examined how sodium ascorbate, a form of Vitamin C, affects chronic atrophic gastritis (CAG). Our study revealed that patients receiving sodium ascorbate showed notable improvements in their blood parameters and overall gastric health.
Furthermore, laboratory studies indicated that sodium ascorbate enhanced cell viability and reduced inflammation markers in treated cells. While we observed promising results, the mechanism through which sodium ascorbate acts includes interactions with key proteins involved in inflammation and cell survival, suggesting its potential as a new therapeutic approach for CAG.
Furthermore, laboratory studies indicated that sodium ascorbate enhanced cell viability and reduced inflammation markers in treated cells. While we observed promising results, the mechanism through which sodium ascorbate acts includes interactions with key proteins involved in inflammation and cell survival, suggesting its potential as a new therapeutic approach for CAG.
2
We conducted a rigorous study to explore the impact of sodium ascorbate, or vitamin C, on individuals suffering from atrophic gastritis. Taking place in Japan, our population-based double-blind trial involved two groups receiving either low or high daily doses of vitamin C over five years.
Despite higher serum ascorbic acid levels in those on the higher dosage, the results showed no significant differences in inflammation markers—C-reactive protein and serum amyloid A—between both groups. Ultimately, our findings suggest that sodium ascorbate does not significantly aid in reducing gastritis-related infections.
Despite higher serum ascorbic acid levels in those on the higher dosage, the results showed no significant differences in inflammation markers—C-reactive protein and serum amyloid A—between both groups. Ultimately, our findings suggest that sodium ascorbate does not significantly aid in reducing gastritis-related infections.
8
We explored the effects of Ascorbic Acid 2-Glucoside (AA2G), a stable form of Vitamin C, on human gastric epithelial cells infected with Helicobacter pylori, a common cause of gastritis and related stomach issues. In our research, we focused on understanding how AA2G could mitigate the damage caused by this bacterium on stomach cells.
Our findings revealed that AA2G significantly reduced oxidative stress—a harmful condition triggered by H. pylori that can damage cells. We observed that treatment with AA2G led to lower levels of harmful substances, such as reactive oxygen species, known to contribute to cell damage.
Notably, AA2G also helped restore the cells' mitochondrial function, which is often impaired during H. pylori infection. This improvement included an increase in ATP levels and enhanced mitochondrial membrane potential, both essential for cell energy production and health.
Ultimately, we found that AA2G effectively reduces the apoptosis (or programmed cell death) that results from H. pylori infection, suggesting that it provides a protective effect on gastric epithelial cells. Our research supports the potential use of AA2G as a beneficial intervention for combatting the adverse effects of H. pylori infection on gastritis.
Our findings revealed that AA2G significantly reduced oxidative stress—a harmful condition triggered by H. pylori that can damage cells. We observed that treatment with AA2G led to lower levels of harmful substances, such as reactive oxygen species, known to contribute to cell damage.
Notably, AA2G also helped restore the cells' mitochondrial function, which is often impaired during H. pylori infection. This improvement included an increase in ATP levels and enhanced mitochondrial membrane potential, both essential for cell energy production and health.
Ultimately, we found that AA2G effectively reduces the apoptosis (or programmed cell death) that results from H. pylori infection, suggesting that it provides a protective effect on gastric epithelial cells. Our research supports the potential use of AA2G as a beneficial intervention for combatting the adverse effects of H. pylori infection on gastritis.
8
We aimed to discover how vitamin C supplementation affects oxidative stress in individuals diagnosed with chronic gastritis. In this study, we looked at 244 Japanese patients suffering from atrophic gastritis. They were randomly assigned to receive either 50 mg or 500 mg of vitamin C every day for five years.
After analyzing the results, we found notable differences between the two groups. The high-dose group experienced a significant decrease in reactive oxygen species (ROS), suggesting that vitamin C may help reduce oxidative stress associated with chronic gastritis. In contrast, the low-dose group reported an increase in ROS levels. These findings prompt further interest in how vitamin C can protect against oxidative stress in similar conditions.
Overall, our study supports the idea that higher doses of vitamin C could have a beneficial effect on oxidative stress, particularly in those dealing with gastritis. This insight opens avenues for considering vitamin C as a potential supportive treatment for managing oxidative stress-related issues in digestive health.
After analyzing the results, we found notable differences between the two groups. The high-dose group experienced a significant decrease in reactive oxygen species (ROS), suggesting that vitamin C may help reduce oxidative stress associated with chronic gastritis. In contrast, the low-dose group reported an increase in ROS levels. These findings prompt further interest in how vitamin C can protect against oxidative stress in similar conditions.
Overall, our study supports the idea that higher doses of vitamin C could have a beneficial effect on oxidative stress, particularly in those dealing with gastritis. This insight opens avenues for considering vitamin C as a potential supportive treatment for managing oxidative stress-related issues in digestive health.
References
- Cheng X, Gu H, Chong Y, Li F, Bei S, et al. Vitamin C Mediates IGFBP7 to Alleviate Chronic Atrophic Gastritis via the HIF-1α/VEGF Pathway. J Cell Mol Med. 2025;29:e70392. doi:10.1111/jcmm.70392
- Ma E, Sasazuki S, Sasaki S, Tsubono Y, Okubo S, et al. Vitamin C supplementation in relation to inflammation in individuals with atrophic gastritis: a randomised controlled trial in Japan. Br J Nutr. 2013;109:1089. doi:10.1017/S0007114512002954
- Sezikli M, Çetinkaya ZA, Güzelbulut F, Çimen B, Özcan Ö, et al. Effects of alpha tocopherol and ascorbic acid on Helicobacter pylori colonization and the severity of gastric inflammation. Helicobacter. 2012;17:127. doi:10.1111/j.1523-5378.2011.00925.x
- Rembiasz K, Budzynski A, Karcz D, Konturek PC, Konturek SJ, et al. Multifocal atrophic gastritis: pathogenesis and therapeutic implications. Eur J Gastroenterol Hepatol. 2005;17:857.
- Kamiya Y, Ohta Y, Imai Y, Arisawa T, Nakano H. A critical role of gastric mucosal ascorbic acid in the progression of acute gastric mucosal lesions induced by compound 48/80 in rats. World J Gastroenterol. 2005;11:1324.
- Sun YQ, Girgensone I, Leanderson P, Petersson F, Borch K. Effects of antioxidant vitamin supplements on Helicobacter pylori-induced gastritis in Mongolian gerbils. Helicobacter. 2005;10:33.
- Mei H, Tu H. Vitamin C and Infection: Current Knowledge and Future Prospects. Front Physiol. 2018;9:1103. doi:10.3389/fphys.2018.01103
- Chen X, Liu R, Liu X, Xu C, Wang X. L-ascorbic Acid-2-Glucoside inhibits Helicobacter pylori-induced apoptosis through mitochondrial pathway in Gastric Epithelial cells. Biomed Pharmacother. 2018;97:75. doi:10.1016/j.biopha.2017.10.030
- Jubiz W, Ramirez M. Effect of vitamin C on the absorption of levothyroxine in patients with hypothyroidism and gastritis. J Clin Endocrinol Metab. 2014;99:E1031. doi:10.1210/jc.2013-4360
- Aditi A, Graham DY. Vitamin C, gastritis, and gastric disease: a historical review and update. Dig Dis Sci. 2012;57:2504. doi:10.1007/s10620-012-2203-7
- Kohler JE, Blass AL, Liu J, Tai K, Soybel DI. Antioxidant pre-treatment prevents omeprazole-induced toxicity in an in vitro model of infectious gastritis. Free Radic Biol Med. 2010;49:786. doi:10.1016/j.freeradbiomed.2010.05.034
- Sasazuki S, Hayashi T, Nakachi K, Sasaki S, Tsubono Y, et al. Protective effect of vitamin C on oxidative stress: a randomized controlled trial. Int J Vitam Nutr Res. 2008;78:121. doi:10.1024/0300-9831.78.3.121
- Draudin-Krylenko VA, Petukhov AB, Kuvshinov IuP, Levchuk AA, Bukin IuV. [Effect of antioxidant use in dietary therapy in patients with chronic athrofic hastritis]. Vopr Pitan. 2006;75:53.
