Last update
3/8/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 6 Reviews
8.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
5-HTP (5-hydroxytryptophan) (from Griffonia simplicifolia Extract) (seed)
50 mg
*
Top Medical Research Studies
9
We delved into the effects of 5-hydroxytryptophan (5-HTP) on the thyroid's response to cold exposure. Our observations indicated that 5-HTP markedly inhibited the thyroid's reaction to cold, highlighting its potential impact. The study showed that other substances influenced this response in various ways, but 5-HTP stood out in its effectiveness. Despite the promising results, it’s important to note that alterations in the thyroid’s responses were closely linked to changes in brain chemistry, rather than direct hormonal influences.
Read More
Most Useful Reviews
9
Cold protection
96 people found this helpful
I have been using vitamins for the past month, and I can confirm they work! My back and neck aches are gone. I felt a cold wind, but after taking vitamins, I didn't even notice it. Recently, my knees were throbbing so badly I had to go to hospital! My friends also said they noticed a difference.
Read More
9
Immune support
Hello everyone! I trust the supplements from this brand! I've tried various ones, and they are of excellent quality at a nice price. I purchased this product for immune support during colds, and it performs this task perfectly. The packaging is convenient, with a tightly closing lid. The capsules are standard size and easy to use.
Read More
9
Immune activation
Previously, I relied on complex vitamins, but now I prefer mono-drugs that are better absorbed. I recommend a fantastic product that boosts the immune system and prevents viruses. These vitamins are affordable, and taking one capsule as disease prevention means a pack lasts ages. They work well; last spring, I didn’t have a cold, and I’ve been taking them regularly for the second week now.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
We delved into the effects of 5-hydroxytryptophan (5-HTP) on the thyroid's response to cold exposure. Our observations indicated that 5-HTP markedly inhibited the thyroid's reaction to cold, highlighting its potential impact. The study showed that other substances influenced this response in various ways, but 5-HTP stood out in its effectiveness. Despite the promising results, it’s important to note that alterations in the thyroid’s responses were closely linked to changes in brain chemistry, rather than direct hormonal influences.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Cold protection
96 people found this helpful
I have been using vitamins for the past month, and I can confirm they work! My back and neck aches are gone. I felt a cold wind, but after taking vitamins, I didn't even notice it. Recently, my knees were throbbing so badly I had to go to hospital! My friends also said they noticed a difference.
Read More
9
Immune support
Hello everyone! I trust the supplements from this brand! I've tried various ones, and they are of excellent quality at a nice price. I purchased this product for immune support during colds, and it performs this task perfectly. The packaging is convenient, with a tightly closing lid. The capsules are standard size and easy to use.
Read More
9
Immune activation
Previously, I relied on complex vitamins, but now I prefer mono-drugs that are better absorbed. I recommend a fantastic product that boosts the immune system and prevents viruses. These vitamins are affordable, and taking one capsule as disease prevention means a pack lasts ages. They work well; last spring, I didn’t have a cold, and I’ve been taking them regularly for the second week now.
Read More
7.5
Mood stabilisation
2 people found this helpful
I absolutely love this supplement. Especially during cold periods and the pandemic, when everything feels overwhelming, 5-HTP gently calms me, preventing despair and aiding sleep with deep phases. For sleep or mood issues, I highly recommend it, alongside melatonin (which I alternate with Swiss melatonin) and GABA. Use it as advised by a doctor or health coach for a maximum of 1-1.5 months, then take a break.
Read More
8
Vitamin C synergy
It's beneficial to use with vitamin C for colds to achieve maximum effect.
Read More
Frequently Asked Questions
9
Immune activation
Previously, I relied on complex vitamins, but now I prefer mono-drugs that are better absorbed. I recommend a fantastic product that boosts the immune system and prevents viruses. These vitamins are affordable, and taking one capsule as disease prevention means a pack lasts ages. They work well; last spring, I didn’t have a cold, and I’ve been taking them regularly for the second week now.
7.5
Cheerfulness boost
I take this drug with the onset of cold weather, and I feel more cheerful. My sleep has improved, and I experience less anxiety.
9
Cold protection
96 people found this helpful
I have been using vitamins for the past month, and I can confirm they work! My back and neck aches are gone. I felt a cold wind, but after taking vitamins, I didn't even notice it. Recently, my knees were throbbing so badly I had to go to hospital! My friends also said they noticed a difference.
9
Immune support
Hello everyone! I trust the supplements from this brand! I've tried various ones, and they are of excellent quality at a nice price. I purchased this product for immune support during colds, and it performs this task perfectly. The packaging is convenient, with a tightly closing lid. The capsules are standard size and easy to use.
7.5
Mood stabilisation
2 people found this helpful
I absolutely love this supplement. Especially during cold periods and the pandemic, when everything feels overwhelming, 5-HTP gently calms me, preventing despair and aiding sleep with deep phases. For sleep or mood issues, I highly recommend it, alongside melatonin (which I alternate with Swiss melatonin) and GABA. Use it as advised by a doctor or health coach for a maximum of 1-1.5 months, then take a break.
8
Vitamin C synergy
It's beneficial to use with vitamin C for colds to achieve maximum effect.
9
We delved into the effects of 5-hydroxytryptophan (5-HTP) on the thyroid's response to cold exposure. Our observations indicated that 5-HTP markedly inhibited the thyroid's reaction to cold, highlighting its potential impact. The study showed that other substances influenced this response in various ways, but 5-HTP stood out in its effectiveness. Despite the promising results, it’s important to note that alterations in the thyroid’s responses were closely linked to changes in brain chemistry, rather than direct hormonal influences.
References
- Hashizume K. Effects of drugs that modify brain biogenic amine concentrations on thyroid activation induced by exposure to cold. Neuroendocrinology. 1976;20:47. PubMed
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