Can NOW Supplements Vitamin C Help with High Cholesterol?
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8
USERS' SCORE
Good
Based on 12 Reviews
8.3
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
1 g (1,000 mg)
1111%
Citrus Bioflavonoid Complex
100 mg
†
Rutin Powder (from Sophora japonica Flower Bud)
25 mg
†
Top Medical Research Studies
9
Vitamin C reduces cholesterol levels
Effect of Using Vitamin C Supplementation on Performance, Blood Parameters, Carcass Characteristics and Meat Quality of Broiler Chickens Under Heat Stress Condition: A Meta-Analysis.
We explored how vitamin C supplementation affects cholesterol levels in broiler chickens, particularly under heat stress conditions. Through a thorough meta-analysis of 35 studies conducted between 1985 and 2023, we assessed various performance metrics, including blood parameters, carcass characteristics, and overall meat quality.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Read More
9
Vitamin C's cholesterol-lowering potential
Vitamin C and E supplementation and high intensity interval training induced changes in lipid profile and haematological variables of young males.
To explore the impact of vitamin C on high cholesterol levels, we designed a study involving 106 young male athletes. They were divided into five groups, including those who did not exercise and those who underwent high-intensity interval training (HIIT), some with added vitamin C, vitamin E, or both. Over eight weeks, we assessed changes in lipid profiles and various blood variables.
Our findings were promising for those taking vitamins C and E alongside regular exercise. Participants who supplemented with these vitamins and engaged in HIIT showed significant drops in body weight, overall fat percentage, total cholesterol, and triglycerides. Remarkably, levels of high-density lipoprotein cholesterol, often dubbed "good cholesterol," increased in all four intervention groups. This suggests a potential role for vitamin C in improving cholesterol levels, especially when paired with an active lifestyle.
However, we also noted some adverse changes—specifically, reductions in certain blood cell counts among those only doing HIIT. While the vitamin-supplemented groups did experience effective elevation in beneficial vitamin levels, the overall effects of vitamin C alone on high cholesterol were less definitive, as the benefits appeared more in combination with exercise. It's safe to say that although vitamin C shows some promise in reducing cholesterol, the strongest benefits occur when it's part of a broader healthy regimen.
Read More
7
Vitamin C affects cholesterol interaction
Joint effects of paraoxonase 1 rs662 polymorphism and vitamins C/E intake on coronary artery disease severity (Gensini and SYNTAX scores) and lipid profile in patients undergoing coronary angiography.
This study aimed to explore how vitamin C intake interacts with a genetic factor known as the paraoxonase (PON) 1 rs662 polymorphism in relation to cholesterol levels. We analyzed data from 428 patients who underwent coronary angiography, focusing on their dietary habits and genetic backgrounds.
We found that individuals carrying the R allele of the polymorphism, especially those with lower vitamin C intake, were more likely to have elevated levels of low-density lipoprotein cholesterol (LDL-C). In fact, higher consumption of vitamin C was linked to a lower risk of high total cholesterol and LDL-C levels. Interestingly, those with the QQ genotype, who did not carry the R allele, did not experience the same level of cholesterol concerns associated with low vitamin C intake.
It’s important to note that while vitamin C appears beneficial in managing cholesterol for some individuals, the genetic factors need to be considered as they significantly influence the outcomes. Overall, our findings suggest that vitamin C can play a role in cholesterol management, particularly for those with specific genetic predispositions, highlighting the importance of personalized nutrition based on genetic makeup.
Read More
Most Useful Reviews
9
Eliminates herpes symptoms
6 people found this helpful
Love this! I've been taking 2g of vitamin C daily and plan to increase it this winter. I've had no colds even with stress and irregular sleep. Remarkably, it stopped a herpes outbreak overnight. I took four capsules before bed when I felt it coming on, and by morning, the symptoms were gone! This unexpected effect was incredible. I hope it works for others, too!
Read More
10
Vital for health
3 people found this helpful
The formula with Rutin is very good. I take a high dosage, as recommended by Linus Pauling. This vitamin C is crucial for my survival since I became chemically sensitive after using Roundup. I find the capsules convenient compared to the hassle of dissolving crystals. I take 18,000mg daily alongside intravenous drips. It truly keeps me functioning, and without it, I believe my health would severely decline.
Read More
9
Blood pressure decrease
2 people found this helpful
Well, I take 8-10 grams a day, along with 5 grams of sustained-release vitamin C. Remarkably, my high blood pressure has vanished, leaving my doctor astonished at my progress without needing medication.
Effect of Using Vitamin C Supplementation on Performance, Blood Parameters, Carcass Characteristics and Meat Quality of Broiler Chickens Under Heat Stress Condition: A Meta-Analysis.
We explored how vitamin C supplementation affects cholesterol levels in broiler chickens, particularly under heat stress conditions. Through a thorough meta-analysis of 35 studies conducted between 1985 and 2023, we assessed various performance metrics, including blood parameters, carcass characteristics, and overall meat quality.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Read More
9
Vitamin C and cholesterol benefits
Synchronizing positive effect of vitamin C and chromium on hyper lipidemia, hyperglycemia, liver enzymes and BMI of diabetes mellitus type 2 patients.
We conducted a study to explore how vitamin C, combined with chromium, affects high cholesterol levels in patients with type 2 diabetes. This interesting research involved 60 participants, evenly split between a treatment group receiving vitamin C (500mg) and chromium (200µg), and a control group taking a placebo.
Our analysis revealed notable reductions in several important lipid measurements within the treatment group. Specifically, we observed a significant drop in total cholesterol and improvements in High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL), and triglyceride levels.
The results illuminate the potential benefits of vitamin C and chromium in managing cholesterol levels for those impacted by type 2 diabetes. While this study doesn't focus solely on vitamin C, the combined effects of both supplements indicate a promising avenue for improving lipid profiles and overall health in diabetic patients.
Read More
9
Vitamin C's cholesterol-lowering potential
Vitamin C and E supplementation and high intensity interval training induced changes in lipid profile and haematological variables of young males.
To explore the impact of vitamin C on high cholesterol levels, we designed a study involving 106 young male athletes. They were divided into five groups, including those who did not exercise and those who underwent high-intensity interval training (HIIT), some with added vitamin C, vitamin E, or both. Over eight weeks, we assessed changes in lipid profiles and various blood variables.
Our findings were promising for those taking vitamins C and E alongside regular exercise. Participants who supplemented with these vitamins and engaged in HIIT showed significant drops in body weight, overall fat percentage, total cholesterol, and triglycerides. Remarkably, levels of high-density lipoprotein cholesterol, often dubbed "good cholesterol," increased in all four intervention groups. This suggests a potential role for vitamin C in improving cholesterol levels, especially when paired with an active lifestyle.
However, we also noted some adverse changes—specifically, reductions in certain blood cell counts among those only doing HIIT. While the vitamin-supplemented groups did experience effective elevation in beneficial vitamin levels, the overall effects of vitamin C alone on high cholesterol were less definitive, as the benefits appeared more in combination with exercise. It's safe to say that although vitamin C shows some promise in reducing cholesterol, the strongest benefits occur when it's part of a broader healthy regimen.
Read More
7
Vitamin C lowers cholesterol in chickens
A comparative study on feeding timing and additive types of broilers in a high-temperature environment.
We observed how the timing of vitamin C (VC) supplementation could influence cholesterol levels in broiler chickens raised in a high-temperature environment. In our study, broiler chickens were given different treatments: some received VC from day one, while others only got it starting on day 22. Our findings indicated that the addition of VC from day one significantly lowered total cholesterol levels, compared to those who did not receive the supplement.
Furthermore, we noticed additional benefits with VC, including improved intestinal health and reduced stress indicators in the chickens. This suggests that early intervention with vitamin C could play a crucial role in managing cholesterol and overall well-being in chickens under heat stress.
Overall, our research highlights the potential of vitamin C as a dietary supplement to tackle high cholesterol in stressful conditions, providing a better understanding of its timing and effectiveness in poultry nutrition.
Read More
7
Vitamin C affects cholesterol interaction
Joint effects of paraoxonase 1 rs662 polymorphism and vitamins C/E intake on coronary artery disease severity (Gensini and SYNTAX scores) and lipid profile in patients undergoing coronary angiography.
This study aimed to explore how vitamin C intake interacts with a genetic factor known as the paraoxonase (PON) 1 rs662 polymorphism in relation to cholesterol levels. We analyzed data from 428 patients who underwent coronary angiography, focusing on their dietary habits and genetic backgrounds.
We found that individuals carrying the R allele of the polymorphism, especially those with lower vitamin C intake, were more likely to have elevated levels of low-density lipoprotein cholesterol (LDL-C). In fact, higher consumption of vitamin C was linked to a lower risk of high total cholesterol and LDL-C levels. Interestingly, those with the QQ genotype, who did not carry the R allele, did not experience the same level of cholesterol concerns associated with low vitamin C intake.
It’s important to note that while vitamin C appears beneficial in managing cholesterol for some individuals, the genetic factors need to be considered as they significantly influence the outcomes. Overall, our findings suggest that vitamin C can play a role in cholesterol management, particularly for those with specific genetic predispositions, highlighting the importance of personalized nutrition based on genetic makeup.
Love this! I've been taking 2g of vitamin C daily and plan to increase it this winter. I've had no colds even with stress and irregular sleep. Remarkably, it stopped a herpes outbreak overnight. I took four capsules before bed when I felt it coming on, and by morning, the symptoms were gone! This unexpected effect was incredible. I hope it works for others, too!
Read More
10
Vital for health
3 people found this helpful
The formula with Rutin is very good. I take a high dosage, as recommended by Linus Pauling. This vitamin C is crucial for my survival since I became chemically sensitive after using Roundup. I find the capsules convenient compared to the hassle of dissolving crystals. I take 18,000mg daily alongside intravenous drips. It truly keeps me functioning, and without it, I believe my health would severely decline.
Read More
9
Blood pressure decrease
2 people found this helpful
Well, I take 8-10 grams a day, along with 5 grams of sustained-release vitamin C. Remarkably, my high blood pressure has vanished, leaving my doctor astonished at my progress without needing medication.
Read More
9
Boosts energy and health
1 people found this helpful
NOW Foods C-1000 has been my go-to for years, providing a robust 1,000mg dose of vitamin C for immune support. The inclusion of bioflavonoids enhances absorption, giving additional antioxidant benefits. After beginning this supplement, I've experienced fewer colds and a boost in energy levels. It aids skin health and collagen production, leaving my skin looking healthier. The capsules are easy to swallow, vegan-friendly, and excellent value for quality.
Read More
9
Strengthens immune response
5 people found this helpful
This vitamin facilitates leukocyte production, essential for eliminating microbes, thus bolstering the body's defences. It is a potent antioxidant, reduces oxidative stress, and plays a pivotal role in synthesising hormones and collagen, which aids in tissue growth. Taken with water at any time of day, it significantly boosts immune cell activity and helps prevent atherosclerosis and controls high cholesterol levels.
High cholesterol, or hyperlipidemia, is a medical condition characterized by an elevated level of cholesterol in the bloodstream. Cholesterol is a waxy, fat-like substance that’s essential for building healthy cells, but too much of it can lead to serious health issues, including heart disease and stroke. Cholesterol is carried through the blood by lipoproteins, with two main types being low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL, often referred to as "bad" cholesterol, can lead to the buildup of plaque in the arteries, while HDL, known as "good" cholesterol, helps carry cholesterol away from the arteries and back to the liver.
Factors contributing to high cholesterol can include poor diet, lack of exercise, obesity, smoking, and genetic predisposition. Regular health screenings are crucial, as high cholesterol often presents no overt symptoms. Maintaining a heart-healthy diet rich in fruits, vegetables, whole grains, and healthy fats, coupled with regular physical activity and avoiding tobacco, can help manage cholesterol levels effectively. In some cases, medications may be necessary to control high cholesterol, so consulting with a healthcare provider is key for tailored advice.
Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that plays a critical role in numerous bodily functions. As an essential nutrient, it contributes to the growth and repair of tissues in the body, and it is vital for the production of collagen, an important protein that helps maintain skin, cartilage, tendons, ligaments, and blood vessels. Additionally, Vitamin C acts as a powerful antioxidant, which means it helps combat free radicals—unstable molecules that can cause oxidative stress and contribute to various chronic diseases.
Moreover, Vitamin C enhances iron absorption from plant-based foods, making it a vital component for those following vegetarian or vegan diets. While many people get sufficient Vitamin C from a well-balanced diet that includes fruits and vegetables like oranges, strawberries, kiwi, broccoli, and bell peppers, some individuals might require supplementation. It's generally recommended to stay within the daily intake guidelines, as excessive consumption can lead to gastrointestinal disturbances. Overall, Vitamin C is not just a skincare celebrity—it's a fundamental part of maintaining overall health and well-being.
Based on user reviews, the timeline for seeing results when taking vitamin C for high cholesterol can vary significantly. Some users report immediate benefits, such as improvements in overall health and immune response, within just a few days of starting their regimen. For instance, one user noticed reduced symptoms of illness, attributing their rapid recovery to their vitamin C intake after starting it just two days into their cold (Read Review). Another user shared that their cholesterol levels showed improvement after incorporating vitamin C into their diet along with regular use over a period, although specific timeframes were not detailed (Read Review).
However, it’s important to note that results can be subjective and dependent on individual health conditions and dosages taken. One user emphasized the antioxidant benefits of vitamin C in controlling cholesterol levels while noting that consistent intake was key to experiencing these health improvements (Read Review). Overall, while some users experienced quick changes, a consistent and prolonged intake of vitamin C may be necessary to achieve significant improvements in cholesterol levels.
Vitamin C has shown potential in managing cholesterol levels, particularly in specific populations or under particular conditions. A study involving patients with type 2 diabetes found that the combination of vitamin C (500 mg) and chromium led to significant reductions in total cholesterol, LDL, and triglyceride levels, highlighting a promising avenue for cholesterol management in diabetic individuals [2]. Additionally, research examining dietary strategies found that individuals with certain genetic predispositions experienced lower cholesterol levels with higher vitamin C intake, suggesting a role for personalized nutrition in cholesterol management [5].
However, the overall landscape of research presents mixed results when considering the effects of vitamin C alone. While some studies involving athletes indicated that vitamin C supplementation could contribute to better cholesterol management when coupled with regular exercise, the impacts of vitamin C by itself remain less conclusive. The effectiveness of vitamin C in reducing cholesterol levels may depend significantly on lifestyle factors, metabolic conditions, and genetic influences. Thus, while vitamin C may support cholesterol management in specific contexts, it should be considered as part of a broader health strategy rather than a standalone solution.
Based on user reviews, many individuals have reported notable improvements in their symptoms after incorporating vitamin C into their daily regimen. For instance, one user indicated that a high dosage of vitamin C effectively halted a herpes outbreak overnight, providing immediate relief from symptoms that had begun to develop (Read Review). Another user experienced a remarkable decrease in high blood pressure, which astonished their doctor, attributing this positive change to their consistent high intake of vitamin C (Read Review). Additional users have reported fewer occurrences of colds and improved energy levels, suggesting a boost in overall immunity and well-being after regular use of vitamin C supplements (Read Review).
Moreover, some users noted improvements in specific health concerns, such as skin health and even symptoms related to vitamin C deficiency, like bleeding gums and dry skin (Read Review). It's essential to highlight that while there are many positive testimonials regarding vitamin C's effects, individual results can greatly vary based on personal health conditions, dosages, and lifestyle factors. For example, one user did not experience the same positive outcomes and found that injections of vitamin C were more effective for them (Read Review). Thus, while vitamin C appears to provide significant benefits for many, individual experiences will differ, and consulting with a healthcare provider is recommended for tailored advice.
Based on user reviews, many individuals have shared their experiences with combining vitamin C supplements with other supplements to manage high cholesterol levels effectively. One user noted that their high blood pressure and cholesterol issues improved significantly after taking high doses of vitamin C alongside sustained-release versions of the nutrient, leading to astonished reactions from their doctor (Read Review). Additionally, users have reported that vitamin C plays a crucial role in controlling cholesterol levels and enhancing cardiovascular health when taken regularly. The antioxidant properties of vitamin C, particularly when combined with bioflavonoids, are also highlighted as beneficial for lowering cholesterol and supporting overall heart health (Read Review).
Moreover, reviews suggest that vitamin C pairs well with other health-focused supplements in their routines. For example, one user found that a high-fat diet supplemented with vitamin C helps improve lipid metabolism, indicating a holistic approach to dietary management (Read Review). However, it’s essential to note that a few users reported mixed results, indicating that personal health conditions and dosages can significantly influence the effectiveness of such combinations (Read Review). In summary, many users advocate for the combination of vitamin C with other supplements as a favorable strategy for addressing cholesterol levels and supporting cardiovascular health.
Based on user reviews, the right dose of Vitamin C for treating high cholesterol seems to vary significantly among individuals. Users report taking high doses, with some reaching up to 18,000 mg daily as part of a broader regimen, including intravenous treatments, claiming it is crucial for their health and contributes to overall well-being Read Review. Other users confirm benefits from doses ranging between 8 to 10 grams daily, also noting improvements in blood pressure and cholesterol levels Read Review.
Several reviews suggest that Vitamin C aids in lowering cholesterol and supporting heart health, with users attesting to noticeable improvements in their overall health after adopting high doses Read ReviewRead Review. However, it’s important to note that high intake of Vitamin C can also lead to side effects, such as gastrointestinal discomfort Read Review. As always, it's wise for individuals to consult a healthcare professional before making significant changes to their vitamin intake, especially at such high levels.
7.5
Faster cold recovery
2 people found this helpful
Recently, I got sick with a cold. Remembering my high-dose vitamin C, I started taking three capsules daily on the second day of illness. Although I feared an allergic reaction to the high dosage, I experienced none. The next day, I felt almost well, despite initially thinking I would be ill for a while. My temperature had risen, and I sought relief for throat pain, but I genuinely believe the vitamin C played a significant role in my rapid recovery.
9
Supports lipid metabolism
1 people found this helpful
For the purpose of dieting, a high-fat diet with no sugar, it arrived five days after I ordered it! The size of the container and the grains surprised me. I bought it to supplement my lipid metabolism due to a high-fat diet without sugar. It is expected to have antioxidant effects. Vitamin C helps promote collagen synthesis, lowers blood cholesterol, and has stress relief benefits. However, excess intake might cause side effects like diarrhoea and abdominal pain.
9
Strengthens immune response
5 people found this helpful
This vitamin facilitates leukocyte production, essential for eliminating microbes, thus bolstering the body's defences. It is a potent antioxidant, reduces oxidative stress, and plays a pivotal role in synthesising hormones and collagen, which aids in tissue growth. Taken with water at any time of day, it significantly boosts immune cell activity and helps prevent atherosclerosis and controls high cholesterol levels.
9
Eliminates herpes symptoms
6 people found this helpful
Love this! I've been taking 2g of vitamin C daily and plan to increase it this winter. I've had no colds even with stress and irregular sleep. Remarkably, it stopped a herpes outbreak overnight. I took four capsules before bed when I felt it coming on, and by morning, the symptoms were gone! This unexpected effect was incredible. I hope it works for others, too!
9
Blood pressure decrease
2 people found this helpful
Well, I take 8-10 grams a day, along with 5 grams of sustained-release vitamin C. Remarkably, my high blood pressure has vanished, leaving my doctor astonished at my progress without needing medication.
9
Boosts energy and health
1 people found this helpful
NOW Foods C-1000 has been my go-to for years, providing a robust 1,000mg dose of vitamin C for immune support. The inclusion of bioflavonoids enhances absorption, giving additional antioxidant benefits. After beginning this supplement, I've experienced fewer colds and a boost in energy levels. It aids skin health and collagen production, leaving my skin looking healthier. The capsules are easy to swallow, vegan-friendly, and excellent value for quality.
7.5
Boosts immunity effectively
4 people found this helpful
BAA Now Foods C-1000 with Rose Hips & Bioflavonoids is a highly effective supplement. Vitamin C is known for boosting immunity and its antioxidant effects while aiding collagen synthesis. The capsules, which are large and oval, cause no discomfort when taken with plenty of water. I previously exhibited symptoms of vitamin C deficiency like bleeding gums and dry skin, but after starting this supplement, I've noticed significant improvements in my overall well-being and energy levels.
2
Not effective as pills
Despite the advertised high dosage, I found this product lacking in effectiveness. After catching a cold with my boyfriend and using it for three days, we realised that injections of ascorbic acid provided better results. This pill format did not meet our needs for elevating vitamin C levels sufficiently.
10
Vital for health
3 people found this helpful
The formula with Rutin is very good. I take a high dosage, as recommended by Linus Pauling. This vitamin C is crucial for my survival since I became chemically sensitive after using Roundup. I find the capsules convenient compared to the hassle of dissolving crystals. I take 18,000mg daily alongside intravenous drips. It truly keeps me functioning, and without it, I believe my health would severely decline.
9
Improves health significantly
1 people found this helpful
My sister had stomach complaints, so we sought out this vitamin C, which my doctor endorsed. It protects heart and blood vessels, lowers blood pressure, cholesterol, and uric acid. My sister and I have long used this antioxidant, and noticeable health improvements followed her regimen. The capsules were initially large but easy to swallow, and her restored immune system is evident.
9
Vitamin C and cholesterol benefits
Synchronizing positive effect of vitamin C and chromium on hyper lipidemia, hyperglycemia, liver enzymes and BMI of diabetes mellitus type 2 patients.
We conducted a study to explore how vitamin C, combined with chromium, affects high cholesterol levels in patients with type 2 diabetes. This interesting research involved 60 participants, evenly split between a treatment group receiving vitamin C (500mg) and chromium (200µg), and a control group taking a placebo.
Our analysis revealed notable reductions in several important lipid measurements within the treatment group. Specifically, we observed a significant drop in total cholesterol and improvements in High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL), and triglyceride levels.
The results illuminate the potential benefits of vitamin C and chromium in managing cholesterol levels for those impacted by type 2 diabetes. While this study doesn't focus solely on vitamin C, the combined effects of both supplements indicate a promising avenue for improving lipid profiles and overall health in diabetic patients.
7
Vitamin C affects cholesterol interaction
Joint effects of paraoxonase 1 rs662 polymorphism and vitamins C/E intake on coronary artery disease severity (Gensini and SYNTAX scores) and lipid profile in patients undergoing coronary angiography.
This study aimed to explore how vitamin C intake interacts with a genetic factor known as the paraoxonase (PON) 1 rs662 polymorphism in relation to cholesterol levels. We analyzed data from 428 patients who underwent coronary angiography, focusing on their dietary habits and genetic backgrounds.
We found that individuals carrying the R allele of the polymorphism, especially those with lower vitamin C intake, were more likely to have elevated levels of low-density lipoprotein cholesterol (LDL-C). In fact, higher consumption of vitamin C was linked to a lower risk of high total cholesterol and LDL-C levels. Interestingly, those with the QQ genotype, who did not carry the R allele, did not experience the same level of cholesterol concerns associated with low vitamin C intake.
It’s important to note that while vitamin C appears beneficial in managing cholesterol for some individuals, the genetic factors need to be considered as they significantly influence the outcomes. Overall, our findings suggest that vitamin C can play a role in cholesterol management, particularly for those with specific genetic predispositions, highlighting the importance of personalized nutrition based on genetic makeup.
References
Tavakolinasab F, Hashemi M. Effect of Using Vitamin C Supplementation on Performance, Blood Parameters, Carcass Characteristics and Meat Quality of Broiler Chickens Under Heat Stress Condition: A Meta-Analysis. J Anim Physiol Anim Nutr (Berl). 2025. doi:10.1111/jpn.14091
Sabar N, Hussain MI, Saleem H, Khan MA, Khalid H, et al. Synchronizing positive effect of vitamin C and chromium on hyper lipidemia, hyperglycemia, liver enzymes and BMI of diabetes mellitus type 2 patients. Pak J Pharm Sci. 2024;37:199.
Son J, Lee WD, Kim H, Hong EC, Kim HJ, et al. A comparative study on feeding timing and additive types of broilers in a high-temperature environment. J Anim Sci. 2023;101. doi:10.1093/jas/skad290
Sarkar S, Dey SK, Datta G, Bandyopadhyay A. Vitamin C and E supplementation and high intensity interval training induced changes in lipid profile and haematological variables of young males. Sports Med Health Sci. 2023;5:137. doi:10.1016/j.smhs.2023.03.006
Darand M, Salehi-Abargouei A, Vahidi Mehrjardi MY, Feizi A, Seyedhossaini SM, et al. Joint effects of paraoxonase 1 rs662 polymorphism and vitamins C/E intake on coronary artery disease severity (Gensini and SYNTAX scores) and lipid profile in patients undergoing coronary angiography. Front Nutr. 2022;9:1097411. doi:10.3389/fnut.2022.1097411
Omidi S, Bouyeh M, Seidavi A. The effect of vitamin C and aspirin supplementation on the performance of turkeys under normal conditions. Anim Biotechnol. 2023;34:3395. doi:10.1080/10495398.2022.2152037